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Lei Duan

Concepts (286)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
91
3.570
Why?
Drug Resistance, Neoplasm
9
2024
79
3.490
Why?
Proto-Oncogene Proteins c-akt
8
2022
54
2.740
Why?
Imidazoles
7
2019
73
2.630
Why?
Piperazines
7
2019
91
2.580
Why?
Receptors, Estrogen
6
2022
70
2.530
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
356
2.470
Why?
Autophagy
8
2022
31
2.340
Why?
Antineoplastic Agents
9
2024
260
2.210
Why?
Breast Neoplasms
9
2022
376
1.960
Why?
Cell Line, Tumor
19
2024
272
1.870
Why?
Tamoxifen
4
2022
30
1.810
Why?
Lung Neoplasms
4
2023
691
1.690
Why?
Cisplatin
5
2022
95
1.450
Why?
Triple Negative Breast Neoplasms
3
2024
16
1.240
Why?
Apoptosis
9
2019
260
1.220
Why?
Gene Expression Regulation, Neoplastic
3
2024
112
1.100
Why?
Carboxypeptidases
3
2022
6
1.060
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
6
1.040
Why?
Neoplasms
2
2018
261
1.010
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.940
Why?
Glycolysis
3
2018
21
0.830
Why?
Retinoblastoma-Like Protein p130
1
2022
2
0.800
Why?
Fatty Acids
1
2021
41
0.770
Why?
Signal Transduction
8
2022
498
0.770
Why?
Neoplasm Recurrence, Local
1
2022
230
0.760
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.730
Why?
Humans
37
2024
30997
0.680
Why?
Phosphatidylinositol 3-Kinases
2
2021
47
0.650
Why?
Insulin Receptor Substrate Proteins
2
2020
14
0.650
Why?
Ketoglutaric Acids
1
2018
2
0.640
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.640
Why?
ErbB Receptors
3
2010
81
0.630
Why?
Sp1 Transcription Factor
1
2018
8
0.630
Why?
Proto-Oncogene Proteins c-cbl
5
2010
15
0.630
Why?
Ubiquitin-Protein Ligases
4
2007
39
0.580
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
31
0.580
Why?
Cell Lineage
1
2015
31
0.510
Why?
Protein Kinase Inhibitors
2
2017
57
0.480
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
28
0.470
Why?
Serine Endopeptidases
1
2014
16
0.470
Why?
Sirolimus
1
2014
17
0.470
Why?
Protein Kinases
1
2014
15
0.460
Why?
Nitric Oxide
1
2014
103
0.460
Why?
Enzyme Activation
6
2014
113
0.450
Why?
Proto-Oncogene Proteins
2
2004
33
0.450
Why?
Mice
12
2022
1683
0.450
Why?
MCF-7 Cells
3
2021
17
0.440
Why?
cdc42 GTP-Binding Protein
2
2010
6
0.440
Why?
rac1 GTP-Binding Protein
2
2010
13
0.430
Why?
rhoA GTP-Binding Protein
2
2009
8
0.430
Why?
Mammary Glands, Human
2
2009
7
0.420
Why?
Receptors, Glycine
2
2009
2
0.420
Why?
Paclitaxel
2
2022
76
0.410
Why?
RNA, Small Interfering
3
2019
66
0.400
Why?
Animals
16
2022
4723
0.390
Why?
Cytotoxins
1
2010
5
0.370
Why?
Epithelial Cells
2
2010
91
0.370
Why?
Adherens Junctions
1
2010
5
0.370
Why?
Neoplasm Proteins
1
2010
55
0.360
Why?
Cell Movement
1
2010
105
0.350
Why?
Cell Proliferation
1
2010
204
0.350
Why?
Morphogenesis
1
2009
8
0.340
Why?
Methylation
2
2019
7
0.330
Why?
Osteosarcoma
3
2018
35
0.330
Why?
Histones
2
2019
28
0.330
Why?
Caffeine
1
2009
66
0.330
Why?
Ubiquitin
5
2007
26
0.330
Why?
Cell Survival
4
2019
164
0.320
Why?
Cell Cycle Checkpoints
2
2022
6
0.320
Why?
Bone Neoplasms
3
2018
120
0.300
Why?
Kidney
1
2009
181
0.300
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
10
0.290
Why?
Antineoplastic Agents, Hormonal
2
2021
18
0.280
Why?
Checkpoint Kinase 1
2
2019
5
0.280
Why?
RNA Interference
2
2019
34
0.280
Why?
Phosphorylation
6
2016
164
0.280
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.280
Why?
Mycobacterium tuberculosis
2
2005
19
0.270
Why?
Gene Knockdown Techniques
2
2018
43
0.270
Why?
Cell Line
6
2013
305
0.270
Why?
Female
11
2024
16983
0.270
Why?
Mitochondria
2
2005
87
0.260
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
7
0.250
Why?
Nitrogen
1
2004
4
0.240
Why?
Soil
1
2004
6
0.240
Why?
Receptors, Antigen
1
2004
1
0.240
Why?
Oxygen
2
2015
87
0.240
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.240
Why?
Biomarkers, Tumor
2
2024
217
0.240
Why?
Trastuzumab
2
2022
26
0.230
Why?
Histone Deacetylase 1
1
2023
2
0.230
Why?
Retinoblastoma Protein
1
2023
10
0.230
Why?
Interleukin-6
1
2024
112
0.230
Why?
Benzamides
1
2023
21
0.220
Why?
Lysosomes
1
2003
26
0.220
Why?
Histone Demethylases
1
2022
2
0.220
Why?
Lysine
1
2022
13
0.210
Why?
Mitochondrial Swelling
1
2002
1
0.210
Why?
Cadherins
1
2022
37
0.210
Why?
Estrogen Receptor alpha
1
2022
15
0.210
Why?
CD27 Ligand
1
2022
2
0.210
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.210
Why?
Nanoparticles
1
2022
14
0.210
Why?
Antigens, CD
1
2022
101
0.210
Why?
Antineoplastic Agents, Immunological
1
2022
19
0.200
Why?
Aurora Kinase A
1
2022
2
0.200
Why?
Aurora Kinase B
1
2022
2
0.200
Why?
Glioblastoma
1
2022
14
0.200
Why?
Macrophages
1
2002
137
0.200
Why?
Oxidation-Reduction
1
2021
72
0.190
Why?
Brain Neoplasms
1
2022
133
0.180
Why?
Receptor, ErbB-2
3
2022
49
0.180
Why?
Receptor, IGF Type 1
2
2017
21
0.170
Why?
Autophagy-Related Proteins
1
2019
2
0.170
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
3
0.170
Why?
A549 Cells
1
2018
9
0.160
Why?
Pentose Phosphate Pathway
1
2018
3
0.160
Why?
Adenosine
1
2018
11
0.150
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
30
0.150
Why?
Heterocyclic Compounds, 3-Ring
2
2017
14
0.150
Why?
Mutation
4
2010
409
0.150
Why?
Cell Transformation, Neoplastic
2
2009
41
0.150
Why?
Receptors, Somatomedin
1
2017
4
0.150
Why?
Phospholipase C gamma
2
2007
10
0.150
Why?
Epidermal Growth Factor
2
2010
33
0.140
Why?
Loss of Heterozygosity
1
2016
4
0.130
Why?
DNA Mismatch Repair
1
2016
7
0.130
Why?
Biological Assay
1
2016
9
0.130
Why?
Protein-Tyrosine Kinases
2
2007
21
0.130
Why?
Macrolides
1
2015
5
0.130
Why?
Caspase 8
1
2015
11
0.130
Why?
Superoxides
1
2015
26
0.130
Why?
Chloroquine
1
2015
12
0.130
Why?
Microscopy, Electron, Transmission
1
2015
28
0.130
Why?
Cellular Senescence
1
2015
19
0.130
Why?
Microscopy, Electron
1
2015
75
0.130
Why?
Microscopy, Confocal
1
2015
118
0.130
Why?
Flow Cytometry
1
2015
204
0.120
Why?
Colorectal Neoplasms
1
2016
91
0.120
Why?
DNA Methylation
1
2016
134
0.120
Why?
Phagosomes
1
2014
3
0.120
Why?
Microtubule-Associated Proteins
1
2014
21
0.120
Why?
Nitric Oxide Synthase Type III
1
2014
17
0.120
Why?
Protein Processing, Post-Translational
1
2014
36
0.120
Why?
DNA Primers
1
2014
53
0.120
Why?
MAP Kinase Signaling System
1
2014
38
0.120
Why?
Nitric Oxide Synthase Type II
1
2014
65
0.120
Why?
Base Sequence
1
2014
134
0.120
Why?
Models, Biological
1
2016
346
0.110
Why?
DNA Damage
1
2014
31
0.110
Why?
Transfection
3
2020
126
0.110
Why?
Gene Expression Regulation
2
2007
287
0.110
Why?
Cell Adhesion
2
2010
46
0.110
Why?
Membrane Potentials
2
2005
191
0.110
Why?
Aniline Compounds
1
2013
46
0.110
Why?
Triazoles
1
2013
34
0.110
Why?
Dose-Response Relationship, Drug
2
2011
442
0.100
Why?
Triterpenes
1
2011
2
0.090
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
8
0.090
Why?
Ubiquitination
1
2010
12
0.090
Why?
Protein Transport
1
2010
40
0.090
Why?
Actins
1
2010
46
0.090
Why?
Cytoskeleton
1
2010
52
0.090
Why?
Amino Acid Sequence
1
2010
195
0.090
Why?
Molecular Sequence Data
1
2010
247
0.090
Why?
Cell Line, Transformed
1
2009
18
0.090
Why?
Mice, Nude
3
2020
36
0.080
Why?
Precancerous Conditions
1
2009
21
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
337
0.080
Why?
Urodela
1
2008
1
0.080
Why?
Retinal Ganglion Cells
1
2008
3
0.080
Why?
Neural Inhibition
1
2008
11
0.080
Why?
Glycine
1
2008
12
0.080
Why?
Synaptic Transmission
1
2008
45
0.080
Why?
RNA, Messenger
2
2013
329
0.080
Why?
Xenograft Model Antitumor Assays
2
2022
25
0.080
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
4
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
8
0.070
Why?
Neovascularization, Physiologic
1
2007
23
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.070
Why?
Necrosis
2
2005
32
0.070
Why?
Cells, Cultured
2
2008
686
0.060
Why?
Macrophages, Alveolar
1
2005
4
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
66
0.060
Why?
Immune Tolerance
1
2004
21
0.060
Why?
China
1
2004
57
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
33
0.060
Why?
Hydrogen-Ion Concentration
1
2004
150
0.060
Why?
Oncogene Proteins
1
2003
5
0.060
Why?
CHO Cells
1
2003
11
0.060
Why?
Mice, Knockout
1
2004
323
0.050
Why?
Cricetinae
1
2003
37
0.050
Why?
Embryo, Mammalian
1
2003
30
0.050
Why?
Endosomes
1
2003
8
0.050
Why?
Endocytosis
1
2003
17
0.050
Why?
Temperature
1
2003
74
0.050
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Ionophores
1
2002
3
0.050
Why?
Calcimycin
1
2002
5
0.050
Why?
Ruthenium Red
1
2002
8
0.050
Why?
Cytochrome c Group
1
2002
7
0.050
Why?
Blotting, Western
1
2003
178
0.050
Why?
Blood Bactericidal Activity
1
2002
6
0.050
Why?
Fibroblasts
1
2003
93
0.050
Why?
Down-Regulation
1
2003
113
0.050
Why?
Caspases
1
2002
33
0.050
Why?
Intracellular Membranes
1
2002
32
0.050
Why?
Caspase 9
1
2022
12
0.050
Why?
Calcium-Binding Proteins
1
2002
24
0.050
Why?
Caspase 3
1
2022
30
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Permeability
1
2002
139
0.050
Why?
Gene Expression
1
2003
239
0.050
Why?
Molecular Docking Simulation
1
2022
1
0.050
Why?
Genistein
1
2022
3
0.050
Why?
Calcium Channels
1
2002
125
0.050
Why?
Protein Binding
3
2007
124
0.050
Why?
Structure-Activity Relationship
2
2013
43
0.040
Why?
Luciferases
2
2013
24
0.040
Why?
Pyrazines
1
2017
13
0.040
Why?
Reproductive History
1
2017
1
0.040
Why?
Disease Models, Animal
1
2020
782
0.040
Why?
Receptors, Progesterone
1
2017
33
0.040
Why?
Receptor Cross-Talk
1
2016
7
0.030
Why?
Population Surveillance
1
2017
123
0.030
Why?
Odds Ratio
1
2017
291
0.030
Why?
Tyrosine
2
2007
26
0.030
Why?
Protein Structure, Tertiary
2
2007
63
0.030
Why?
Case-Control Studies
1
2017
662
0.030
Why?
Computer Simulation
1
2016
222
0.030
Why?
Risk Assessment
1
2017
718
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
14
0.030
Why?
Biological Availability
1
2013
25
0.030
Why?
Genes, Reporter
1
2013
29
0.030
Why?
Transcription, Genetic
1
2013
107
0.030
Why?
Administration, Oral
1
2013
139
0.030
Why?
Rats, Sprague-Dawley
1
2013
468
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
8
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
6
0.020
Why?
Drug Evaluation, Preclinical
1
2011
34
0.020
Why?
Tumor Burden
1
2011
33
0.020
Why?
Rats
1
2013
873
0.020
Why?
Mice, SCID
1
2011
58
0.020
Why?
Quinazolines
1
2011
27
0.020
Why?
Young Adult
1
2017
2063
0.020
Why?
Male
2
2020
16445
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
115
0.020
Why?
Risk Factors
1
2017
2588
0.020
Why?
Antibodies, Monoclonal
1
2011
271
0.020
Why?
rho-Associated Kinases
1
2009
6
0.020
Why?
Telomerase
1
2009
10
0.020
Why?
Protein Kinase C
1
2009
47
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
80
0.020
Why?
Retina
1
2008
12
0.020
Why?
Ligands
1
2007
57
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Binding Sites
1
2007
75
0.020
Why?
Laminin
1
2007
8
0.020
Why?
Mutagenesis, Site-Directed
1
2007
19
0.020
Why?
Drug Combinations
1
2007
68
0.020
Why?
Gene Silencing
1
2007
24
0.020
Why?
Tumor Cells, Cultured
1
2007
149
0.020
Why?
Collagen
1
2007
103
0.020
Why?
Enzyme Inhibitors
1
2007
144
0.020
Why?
Wound Healing
1
2007
174
0.020
Why?
Proteoglycans
1
2007
345
0.020
Why?
Receptors, Purinergic P2
1
2005
1
0.020
Why?
Cytochromes c
1
2005
15
0.020
Why?
Adenosine Triphosphate
1
2005
43
0.020
Why?
Cyclosporine
1
2005
17
0.020
Why?
Molecular Conformation
1
2004
15
0.010
Why?
Adult
1
2017
8931
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
13
0.010
Why?
Precipitin Tests
1
2003
13
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
36
0.010
Why?
Immunoblotting
1
2003
52
0.010
Why?
Plasmids
1
2003
45
0.010
Why?
Models, Genetic
1
2003
38
0.010
Why?
Middle Aged
1
2017
10195
0.010
Why?
Mice, Transgenic
1
2003
261
0.010
Why?
Time Factors
1
2003
1672
0.010
Why?
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