Structure-Activity Relationship
"Structure-Activity Relationship" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The relationship between the chemical structure of a compound and its biological or pharmacological activity. Compounds are often classed together because they have structural characteristics in common including shape, size, stereochemical arrangement, and distribution of functional groups.
| Descriptor ID |
D013329
|
| MeSH Number(s) |
G02.111.830 G07.690.773.997
|
| Concept/Terms |
Structure-Activity Relationship- Structure-Activity Relationship
- Relationship, Structure-Activity
- Relationships, Structure-Activity
- Structure Activity Relationship
- Structure-Activity Relationships
|
Below are MeSH descriptors whose meaning is more general than "Structure-Activity Relationship".
Below are MeSH descriptors whose meaning is more specific than "Structure-Activity Relationship".
This graph shows the total number of publications written about "Structure-Activity Relationship" by people in this website by year, and whether "Structure-Activity Relationship" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 3 | 3 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 4 | 4 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2021 | 0 | 2 | 2 |
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Below are the most recent publications written about "Structure-Activity Relationship" by people in Profiles.
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Taking Advantage of the Morpheein Behavior of Peroxiredoxin in Bionanotechnology. Bioconjug Chem. 2021 01 20; 32(1):43-62.
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Characterization of Dopamine Receptor Associated Drugs on the Proliferation and Apoptosis of Prostate Cancer Cell Lines. Anticancer Agents Med Chem. 2021; 21(9):1160-1171.
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Two novel camptothecin derivatives inhibit colorectal cancer proliferation via induction of cell cycle arrest and apoptosis in vitro and in vivo. Eur J Pharm Sci. 2018 Oct 15; 123:546-559.
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CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor. Nat Commun. 2017 02 23; 8(1):7.
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Convallatoxin-Induced Reduction of Methionine Import Effectively Inhibits Human Cytomegalovirus Infection and Replication. J Virol. 2016 Dec 01; 90(23):10715-10727.
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Identification and characterization of PPARa ligands in the hippocampus. Nat Chem Biol. 2016 Dec; 12(12):1075-1083.
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The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004279.
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Synthesis and evaluation of 1,4-naphthoquinone ether derivatives as SmTGR inhibitors and new anti-schistosomal drugs. FEBS J. 2015 Aug; 282(16):3199-217.
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Discovery of oxathiapiprolin, a new oomycete fungicide that targets an oxysterol binding protein. Bioorg Med Chem. 2016 Feb 01; 24(3):354-61.
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Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers. Chem Res Toxicol. 2015 Jun 15; 28(6):1265-74.