"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
| Descriptor ID |
D015854
|
| MeSH Number(s) |
G02.111.905 G05.308.850 G07.690.773.998
|
| Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
|
Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 3 | 4 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 5 | 6 |
| 2004 | 0 | 2 | 2 |
| 2005 | 1 | 2 | 3 |
| 2006 | 1 | 7 | 8 |
| 2007 | 0 | 9 | 9 |
| 2008 | 1 | 6 | 7 |
| 2009 | 0 | 4 | 4 |
| 2010 | 0 | 3 | 3 |
| 2011 | 3 | 2 | 5 |
| 2012 | 3 | 2 | 5 |
| 2013 | 3 | 4 | 7 |
| 2014 | 2 | 2 | 4 |
| 2015 | 1 | 5 | 6 |
| 2016 | 1 | 2 | 3 |
| 2017 | 0 | 2 | 2 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 5 | 7 |
| 2020 | 2 | 2 | 4 |
| 2021 | 3 | 3 | 6 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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Regression of Triple-Negative Breast Cancer in a Patient-Derived Xenograft Mouse Model by Monoclonal Antibodies against IL-12 p40 Monomer. Cells. 2022 01 13; 11(2).
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Inhibition of dipeptidyl-peptidase 4 induces upregulation of the late cornified envelope cluster in keratinocytes. Arch Dermatol Res. 2022 Nov; 314(9):909-915.
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Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease. Nat Neurosci. 2021 06; 24(6):786-798.
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Upregulated Angiogenesis Is Incompetent to Rescue Dilated Cardiomyopathy Phenotype in Mice. Cells. 2021 03 31; 10(4).
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Upregulation of transient receptor potential melastatin 4 (TRPM4) in ventricular fibroblasts from heart failure patients. Pflugers Arch. 2021 03; 473(3):521-531.
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Perivascular Adipose Tissue Inflammation in Ischemic Heart Disease. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1239-1250.
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Dysregulated microRNA expression in IL-4 transgenic mice, an animal model of atopic dermatitis. Arch Dermatol Res. 2021 Dec; 313(10):837-846.
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Oleamide, a Sleep-Inducing Supplement, Upregulates Doublecortin in Hippocampal Progenitor Cells via PPARa. J Alzheimers Dis. 2021; 84(4):1747-1762.
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Dantrolene hinders dengue virus-induced upregulation and translocation of calmodulin to cardiac cell nuclei. Virology. 2021 01 15; 553:81-93.
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Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not ?-Amyloid Accumulation. Cell Rep. 2020 09 22; 32(12):108169.