"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
|
| MeSH Number(s) |
G05.308.203
|
| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
|
Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 2 | 0 | 2 |
| 2009 | 3 | 0 | 3 |
| 2010 | 0 | 2 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 3 | 1 | 4 |
| 2014 | 2 | 3 | 5 |
| 2015 | 2 | 2 | 4 |
| 2016 | 1 | 2 | 3 |
| 2017 | 2 | 2 | 4 |
| 2018 | 2 | 4 | 6 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 2 | 3 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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Role of epigenetics in pancreatic ductal adenocarcinoma. Epigenomics. 2023 01; 15(2):89-110.
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Aging the brain: multi-region methylation principal component based clock in the context of Alzheimer's disease. Aging (Albany NY). 2022 07 30; 14(14):5641-5668.
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Innate Immune Memory and the Host Response to Infection. J Immunol. 2022 02 15; 208(4):785-792.
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Epigenetic Dysregulation of 5-hydroxymethylcytosine in Well-Differentiated Pancreatic Neuroendocrine Tumors. Appl Immunohistochem Mol Morphol. 2022 02 01; 30(2):e11-e15.
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Evidence for age-related contributions of DNA damage and epigenetics in brain tumorigenesis. Int J Exp Pathol. 2021 12; 102(6):232-241.
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Analysis of Gene Expression Patterns of Epigenetic Enzymes Dnmt3a, Tet1 and Ogt in Murine Chondrogenic Models. Cells. 2021 10 06; 10(10).
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A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer's disease. Nat Commun. 2021 07 22; 12(1):4472.
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Neonatal thyroxine activation modifies epigenetic programming of the liver. Nat Commun. 2021 07 21; 12(1):4446.
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The association of epigenetic clocks in brain tissue with brain pathologies and common aging phenotypes. Neurobiol Dis. 2021 09; 157:105428.
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A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex. Nat Commun. 2021 06 10; 12(1):3517.