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Kalipada Pahan

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentNeurological Sciences
AddressChicago IL 60612
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    Collapse Overview 
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    My Scopus ID is 7004724512.
    My NIH COMMONS name is PAHAN.KALIPADA.

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sheinin M, Mondal S, Pahan K. Neutralization of p40 Homodimer and p40 Monomer Leads to Tumor Regression in Patient-Derived Xenograft Mice with Pancreatic Cancer. Cancers (Basel). 2023 Dec 11; 15(24). PMID: 38136341.
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    2. Raha S, Dutta D, Paidi RK, Pahan K. Lipid-Lowering Drug Gemfibrozil Protects Mice from Tay-Sachs Disease via Peroxisome Proliferator-Activated Receptor a. Cells. 2023 Dec 08; 12(24). PMID: 38132111.
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    3. Jana M, Mondal S, Jana A, Pahan K. Induction of IL-2 by interleukin-12 p40 homodimer and IL-12, but not IL-23, in microglia and macrophages: Implications for multiple sclerosis. Cytokine. 2024 Feb; 174:156457. PMID: 38056248.
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    4. Dutta D, Jana M, Paidi RK, Majumder M, Raha S, Dasarathy S, Pahan K. Tau fibrils induce glial inflammation and neuropathology via TLR2 in Alzheimer's disease-related mouse models. J Clin Invest. 2023 09 15; 133(18). PMID: 37552543.
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    5. Chakrabarti S, Gorai S, Pahan K. A simple protocol for isolating microglia from adult mouse brain. NeuroImmune Pharm Ther. 2023 Sep; 2(3):293-300. PMID: 37885917.
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    6. Sheinin M, Mondal S, Roy A, Gorai S, Rangasamy SB, Poddar J, Pahan K. Suppression of Experimental Autoimmune Encephalomyelitis in Mice by ?-Hydroxy ?-Methylbutyrate, a Body-Building Supplement in Humans. J Immunol. 2023 07 15; 211(2):187-198. PMID: 37314416.
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    7. Paidi RK, Raha S, Roy A, Pahan K. Muscle-building supplement ?-hydroxy ?-methylbutyrate binds to PPARa to improve hippocampal functions in mice. Cell Rep. 2023 07 25; 42(7):112717. PMID: 37437568.
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    8. Paidi RK, Jana M, Raha S, Mishra RK, Jeong B, Sheinin M, Pahan K. Prenol, but Not Vitamin C, of Fruit Binds to SARS-CoV-2 Spike S1 to Inhibit Viral Entry: Implications for COVID-19. J Immunol. 2023 06 15; 210(12):1938-1949. PMID: 37144841.
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    9. Jana M, Dasarathy S, Ghosh S, Pahan K. Upregulation of DJ-1 in Dopaminergic Neurons by a Physically-Modified Saline: Implications for Parkinson's Disease. Int J Mol Sci. 2023 Feb 28; 24(5). PMID: 36902085.
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    10. Pahan S, Raha S, Dasarathi S, Pahan K. Cinnamein Inhibits the Induction of Nitric Oxide and Proinflammatory Cytokines in Macrophages, Microglia and Astrocytes. J Clin Exp Immunol. 2023; 8(1):520-529. PMID: 36848307.
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    11. Jana M, Dutta D, Poddar J, Pahan K. Activation of PPARa Exhibits Therapeutic Efficacy in a Mouse Model of Juvenile Neuronal Ceroid Lipofuscinosis. J Neurosci. 2023 03 08; 43(10):1814-1829. PMID: 36697260.
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    12. Rangasamy SB, Poddar J, Pahan K. Protection of Mice from Controlled Cortical Impact Injury by Food Additive Glyceryl Tribenzoate. Int J Mol Sci. 2023 Jan 20; 24(3). PMID: 36768402.
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    13. Rangasamy SB, Jana M, Dasarathi S, Kundu M, Pahan K. Treadmill workout activates PPARa in the hippocampus to upregulate ADAM10, decrease plaques and improve cognitive functions in 5XFAD mouse model of Alzheimer's disease. Brain Behav Immun. 2023 03; 109:204-218. PMID: 36682514.
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    14. Sheinin M, Jeong B, Paidi RK, Pahan K. Regression of Lung Cancer in Mice by Intranasal Administration of SARS-CoV-2 Spike S1. Cancers (Basel). 2022 Nov 17; 14(22). PMID: 36428739.
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    15. Dutta D, Paidi RK, Raha S, Roy A, Chandra S, Pahan K. Treadmill exercise reduces a-synuclein spreading via PPARa. Cell Rep. 2022 07 12; 40(2):111058. PMID: 35830804.
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    16. Rangasamy SB, Dutta D, Mondal S, Majumder M, Dasarathy S, Chandra G, Pahan K. Protection of dopaminergic neurons in hemiparkinsonian monkeys by flavouring ingredient glyceryl tribenzoate. NeuroImmune Pharm Ther. 2022 Mar 25; 1(1):7-22. PMID: 36720111.
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    17. Kundu M, Raha S, Roy A, Pahan K. Regression of Triple-Negative Breast Cancer in a Patient-Derived Xenograft Mouse Model by Monoclonal Antibodies against IL-12 p40 Monomer. Cells. 2022 01 13; 11(2). PMID: 35053375.
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    18. Rangasamy SB, Raha S, Dasarathy S, Pahan K. Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Improves Cognitive Functions in Mice after Controlled Cortical Impact Injury. Int J Mol Sci. 2021 Dec 24; 23(1). PMID: 35008615.
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    19. Raha S, Ghosh A, Dutta D, Patel DR, Pahan K. Activation of PPARa enhances astroglial uptake and degradation of ?-amyloid. Sci Signal. 2021 Oct 26; 14(706):eabg4747. PMID: 34699252.
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    20. Paidi RK, Jana M, Raha S, McKay M, Sheinin M, Mishra RK, Pahan K. Eugenol, a Component of Holy Basil (Tulsi) and Common Spice Clove, Inhibits the Interaction Between SARS-CoV-2 Spike S1 and ACE2 to Induce Therapeutic Responses. J Neuroimmune Pharmacol. 2021 12; 16(4):743-755. PMID: 34677731.
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    21. Pahan S, Dasarathi S, Pahan K. Glyceryl tribenzoate: A food additive with unique properties to be a substitute for cinnamon. J Clin Exp Immunol. 2021; 6(5):367-372. PMID: 34723288.
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    22. Paidi RK, Jana M, Mishra RK, Dutta D, Pahan K. Selective Inhibition of the Interaction between SARS-CoV-2 Spike S1 and ACE2 by SPIDAR Peptide Induces Anti-Inflammatory Therapeutic Responses. J Immunol. 2021 11 15; 207(10):2521-2533. PMID: 34645689.
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    23. Dutta D, Jana M, Majumder M, Mondal S, Roy A, Pahan K. Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo. Nat Commun. 2021 09 10; 12(1):5382. PMID: 34508096.
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    24. Chakrabarti S, Prorok T, Roy A, Patel D, Dasarathi S, Pahan K. Upregulation of IL-1 Receptor Antagonist by Aspirin in Glial Cells via Peroxisome Proliferator-Activated Receptor-Alpha. J Alzheimers Dis Rep. 2021; 5(1):647-661. PMID: 34632302.
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    25. Rangasamy SB, Dasarathi S, Nutakki A, Mukherjee S, Nellivalasa R, Pahan K. Stimulation of Dopamine Production by Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive. J Alzheimers Dis Rep. 2021 Apr 23; 5(1):295-310. PMID: 34113786.
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    26. Dutta D, Majumder M, Paidi RK, Pahan K. Alleviation of Huntington pathology in mice by oral administration of food additive glyceryl tribenzoate. Neurobiol Dis. 2021 06; 153:105318. PMID: 33636386.
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    27. Gottschalk CG, Jana M, Roy A, Patel DR, Pahan K. Gemfibrozil Protects Dopaminergic Neurons in a Mouse Model of Parkinson's Disease via PPARa-Dependent Astrocytic GDNF Pathway. J Neurosci. 2021 03 10; 41(10):2287-2300. PMID: 33514677.
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    28. Paidi RK, Jana M, Mishra RK, Dutta D, Raha S, Pahan K. ACE-2-interacting Domain of SARS-CoV-2 (AIDS) Peptide Suppresses Inflammation to Reduce Fever and Protect Lungs and Heart in Mice: Implications for COVID-19 Therapy. J Neuroimmune Pharmacol. 2021 03; 16(1):59-70. PMID: 33426604.
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    29. Mukherjee S, Pahan K. Is COVID-19 Gender-sensitive? J Neuroimmune Pharmacol. 2021 03; 16(1):38-47. PMID: 33405098.
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    30. Roy A, Kundu M, Chakrabarti S, Patel DR, Pahan K. Oleamide, a Sleep-Inducing Supplement, Upregulates Doublecortin in Hippocampal Progenitor Cells via PPARa. J Alzheimers Dis. 2021; 84(4):1747-1762. PMID: 34744082.
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    31. Pahan S, Pahan K. Can cinnamon spice down autoimmune diseases? J Clin Exp Immunol. 2020; 5(6):252-258. PMID: 33294884.
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    32. Raha S, Dutta D, Roy A, Pahan K. Reduction of Lewy Body Pathology by Oral Cinnamon. J Neuroimmune Pharmacol. 2021 09; 16(3):592-608. PMID: 32889602.
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    33. Mondal S, Kundu M, Jana M, Roy A, Rangasamy SB, Modi KK, Wallace J, Albalawi YA, Balabanov R, Pahan K. IL-12 p40 monomer is different from other IL-12 family members to selectively inhibit IL-12R?1 internalization and suppress EAE. Proc Natl Acad Sci U S A. 2020 09 01; 117(35):21557-21567. PMID: 32817415.
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    34. Patel D, Roy A, Raha S, Kundu M, Gonzalez FJ, Pahan K. Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARa. JCI Insight. 2020 05 21; 5(10). PMID: 32315292.
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    35. Pahan P, Pahan K. Smooth or Risky Revisit of an Old Malaria Drug for COVID-19? J Neuroimmune Pharmacol. 2020 06; 15(2):174-180. PMID: 32415419.
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    36. Rangasamy SB, Ghosh S, Pahan K. RNS60, a physically-modified saline, inhibits glial activation, suppresses neuronal apoptosis and protects memory in a mouse model of traumatic brain injury. Exp Neurol. 2020 06; 328:113279. PMID: 32151546.
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    37. Patel D, Roy A, Pahan K. PPARa serves as a new receptor of aspirin for neuroprotection. J Neurosci Res. 2020 04; 98(4):626-631. PMID: 31797405.
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    38. Pahan K. A Broad Application of CRISPR Cas9 in Infectious, Inflammatory and Neurodegenerative Diseases. J Neuroimmune Pharmacol. 2019 12; 14(4):534-536. PMID: 31782056.
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    39. Drohomyrecky PC, Doroshenko ER, Akkermann R, Moshkova M, Yi TJ, Zhao FL, Ahn JJ, McGaha TL, Pahan K, Dunn SE. Peroxisome Proliferator-Activated Receptor-d Acts within Peripheral Myeloid Cells to Limit Th Cell Priming during Experimental Autoimmune Encephalomyelitis. J Immunol. 2019 11 15; 203(10):2588-2601. PMID: 31578267.
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    40. Dutta D, Kundu M, Mondal S, Roy A, Ruehl S, Hall DA, Pahan K. RANTES-induced invasion of Th17 cells into substantia nigra potentiates dopaminergic cell loss in MPTP mouse model of Parkinson's disease. Neurobiol Dis. 2019 12; 132:104575. PMID: 31445159.
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    41. Chakrabarti S, Roy A, Prorok T, Patel D, Dasarathi S, Pahan K. Aspirin up-regulates suppressor of cytokine signaling 3 in glial cells via PPARa. J Neurochem. 2019 10; 151(1):50-63. PMID: 31273781.
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    42. Pahan S, Pahan K. Mode of Action of Aspirin in Experimental Autoimmune Encephalomyelitis. DNA Cell Biol. 2019 Jul; 38(7):593-596. PMID: 31140860.
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    43. Gottschalk CG, Roy A, Jana M, Kundu M, Pahan K. Activation of Peroxisome Proliferator-Activated Receptor-a Increases the Expression of Nuclear Receptor Related 1 Protein (Nurr1) in Dopaminergic Neurons. Mol Neurobiol. 2019 Nov; 56(11):7872-7887. PMID: 31127527.
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    44. Patel D, Jana A, Roy A, Pahan K. Cinnamon and its Metabolite Protect the Nigrostriatum in a Mouse Model of Parkinson's Disease Via Astrocytic GDNF. J Neuroimmune Pharmacol. 2019 09; 14(3):503-518. PMID: 31119595.
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    45. Chandra S, Pahan K. Gemfibrozil, a Lipid-Lowering Drug, Lowers Amyloid Plaque Pathology and Enhances Memory in a Mouse Model of Alzheimer's Disease via Peroxisome Proliferator-Activated Receptor a. J Alzheimers Dis Rep. 2019 May 18; 3(1):149-168. PMID: 31259309.
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    46. Mondal S, Rangasamy SB, Roy A, Dasarathy S, Kordower JH, Pahan K. Low-Dose Maraviroc, an Antiretroviral Drug, Attenuates the Infiltration of T Cells into the Central Nervous System and Protects the Nigrostriatum in Hemiparkinsonian Monkeys. J Immunol. 2019 May 01. PMID: 31043478.
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    47. Chakrabarti S, Chandra S, Roy A, Dasarathi S, Kundu M, Pahan K. Upregulation of tripeptidyl-peptidase 1 by 3-hydroxy-(2,2)-dimethyl butyrate, a brain endogenous ligand of PPARa: Implications for late-infantile Batten disease therapy. Neurobiol Dis. 2019 07; 127:362-373. PMID: 30928643.
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    48. Prorok T, Jana M, Patel D, Pahan K. Cinnamic Acid Protects the Nigrostriatum in a Mouse Model of Parkinson's Disease via Peroxisome Proliferator-Activated Receptora. Neurochem Res. 2019 Apr; 44(4):751-762. PMID: 30612307.
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    49. Chandra S, Roy A, Patel DR, Pahan K. PPARa Between Aspirin and Plaque Clearance. J Alzheimers Dis. 2019; 71(2):389-397. PMID: 31424405.
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    50. Dodiya HB, Forsyth CB, Voigt RM, Engen PA, Patel J, Shaikh M, Green SJ, Naqib A, Roy A, Kordower JH, Pahan K, Shannon KM, Keshavarzian A. Chronic stress-induced gut dysfunction exacerbates Parkinson's disease phenotype and pathology in a rotenone-induced mouse model of Parkinson's disease. Neurobiol Dis. 2020 02; 135:104352. PMID: 30579705.
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    51. Chandra S, Roy A, Jana M, Pahan K. Cinnamic acid activates PPARa to stimulate Lysosomal biogenesis and lower Amyloid plaque pathology in an Alzheimer's disease mouse model. Neurobiol Dis. 2019 04; 124:379-395. PMID: 30578827.
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    52. Yalagala PCR, Sugasini D, Dasarathi S, Pahan K, Subbaiah PV. Dietary lysophosphatidylcholine-EPA enriches both EPA and DHA in the brain: potential treatment for depression. J Lipid Res. 2019 03; 60(3):566-578. PMID: 30530735.
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    53. Mondal S, Jana M, Dasarathi S, Roy A, Pahan K. Aspirin ameliorates experimental autoimmune encephalomyelitis through interleukin-11-mediated protection of regulatory T cells. Sci Signal. 2018 11 27; 11(558). PMID: 30482850.
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    54. Rangasamy SB, Dasarathi S, Pahan P, Jana M, Pahan K. Low-Dose Aspirin Upregulates Tyrosine Hydroxylase and Increases Dopamine Production in Dopaminergic Neurons: Implications for Parkinson's Disease. J Neuroimmune Pharmacol. 2019 06; 14(2):173-187. PMID: 30187283.
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    55. Patel D, Roy A, Kundu M, Jana M, Luan CH, Gonzalez FJ, Pahan K. Aspirin binds to PPARa to stimulate hippocampal plasticity and protect memory. Proc Natl Acad Sci U S A. 2018 07 31; 115(31):E7408-E7417. PMID: 30012602.
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    56. Rangasamy SB, Jana M, Roy A, Corbett GT, Kundu M, Chandra S, Mondal S, Dasarathi S, Mufson EJ, Mishra RK, Luan CH, Bennett DA, Pahan K. Selective disruption of TLR2-MyD88 interaction inhibits inflammation and attenuates Alzheimer's pathology. J Clin Invest. 2018 10 01; 128(10):4297-4312. PMID: 29990310.
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    57. Chandra S, Jana M, Pahan K. Aspirin Induces Lysosomal Biogenesis and Attenuates Amyloid Plaque Pathology in a Mouse Model of Alzheimer's Disease via PPARa. J Neurosci. 2018 07 25; 38(30):6682-6699. PMID: 29967008.
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    58. Musial TF, Molina-Campos E, Bean LA, Ybarra N, Borenstein R, Russo ML, Buss EW, Justus D, Neuman KM, Ayala GD, Mullen SA, Voskobiynyk Y, Tulisiak CT, Fels JA, Corbett NJ, Carballo G, Kennedy CD, Popovic J, Ramos-Franco J, Fill M, Pergande MR, Borgia JA, Corbett GT, Pahan K, Han Y, Chetkovich DM, Vassar RJ, Byrne RW, Matthew Oh M, Stoub TR, Remy S, Disterhoft JF, Nicholson DA. Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease. Neurobiol Learn Mem. 2018 10; 154:141-157. PMID: 29906573.
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    59. Mondal S, Rangasamy SB, Ghosh S, Watson RL, Pahan K. Correction to: Nebulization of RNS60, a Physically-Modified Saline, Attenuates the Adoptive Transfer of Experimental Allergic Encephalomyelitis in Mice: Implications for Multiple Sclerosis Therapy. Neurochem Res. 2018 05; 43(5):1136-1139. PMID: 29611013.
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    60. Chakrabarti S, Jana M, Roy A, Pahan K. Upregulation of Suppressor of Cytokine Signaling 3 in Microglia by Cinnamic Acid. Curr Alzheimer Res. 2018; 15(10):894-904. PMID: 29732971.
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    61. Chandra G, Kundu M, Rangasamy SB, Dasarathy S, Ghosh S, Watson R, Pahan K. Increase in Mitochondrial Biogenesis in Neuronal Cells by RNS60, a Physically-Modified Saline, via Phosphatidylinositol 3-Kinase-Mediated Upregulation of PGC1a. J Neuroimmune Pharmacol. 2018 06; 13(2):143-162. PMID: 29188424.
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    62. Jana M, Ghosh S, Pahan K. Upregulation of Myelin Gene Expression by a Physically-Modified Saline via Phosphatidylinositol 3-Kinase-Mediated Activation of CREB: Implications for Multiple Sclerosis. Neurochem Res. 2018 Feb; 43(2):407-419. PMID: 29143164.
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    63. Kundu M, Roy A, Pahan K. Selective neutralization of IL-12 p40 monomer induces death in prostate cancer cells via IL-12-IFN-?. Proc Natl Acad Sci U S A. 2017 10 24; 114(43):11482-11487. PMID: 29073075.
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    64. Modi KK, Jana A, Ghosh S, Watson R, Pahan K. Correction: A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease. PLoS One. 2017; 12(6):e0180602. PMID: 28654697.
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    65. Kim K, Kleinman HK, Lee HJ, Pahan K. Safety and potential efficacy of gemfibrozil as a supportive treatment for children with late infantile neuronal ceroid lipofuscinosis and other lipid storage disorders. Orphanet J Rare Dis. 2017 06 17; 12(1):113. PMID: 28623936.
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    66. Chandra G, Roy A, Rangasamy SB, Pahan K. Induction of Adaptive Immunity Leads to Nigrostriatal Disease Progression in MPTP Mouse Model of Parkinson's Disease. J Immunol. 2017 06 01; 198(11):4312-4326. PMID: 28446566.
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    67. Ghosh A, Rangasamy SB, Modi KK, Pahan K. Gemfibrozil, food and drug administration-approved lipid-lowering drug, increases longevity in mouse model of late infantile neuronal ceroid lipofuscinosis. J Neurochem. 2017 05; 141(3):423-435. PMID: 28199020.
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    68. Mondal S, Rangasamy SB, Ghosh S, Watson RL, Pahan K. Nebulization of RNS60, a Physically-Modified Saline, Attenuates the Adoptive Transfer of Experimental Allergic Encephalomyelitis in Mice: Implications for Multiple Sclerosis Therapy. Neurochem Res. 2017 May; 42(5):1555-1570. PMID: 28271325.
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    69. Mondal S, Dasarathi S, Pahan K. Glyceryl Tribenzoate: A Flavoring Ingredient, Inhibits the Adoptive Transfer of Experimental Allergic Encephalomyelitis via TGF-?: Implications for Multiple Sclerosis Therapy. J Clin Cell Immunol. 2017 Feb; 8(1). PMID: 28367355.
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    70. Roy A, Kundu M, Jana M, Mishra RK, Yung Y, Luan CH, Gonzalez FJ, Pahan K. Identification and characterization of PPARa ligands in the hippocampus. Nat Chem Biol. 2016 Dec; 12(12):1075-1083. PMID: 27748752.
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    71. Kundu M, Mondal S, Roy A, Martinson JL, Pahan K. Sodium Benzoate, a Food Additive and a Metabolite of Cinnamon, Enriches Regulatory T Cells via STAT6-Mediated Upregulation of TGF-?. J Immunol. 2016 10 15; 197(8):3099-3110. PMID: 27605008.
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    72. Bera S, Kar RK, Mondal S, Pahan K, Bhunia A. Structural Elucidation of the Cell-Penetrating Penetratin Peptide in Model Membranes at the Atomic Level: Probing Hydrophobic Interactions in the Blood-Brain Barrier. Biochemistry. 2016 09 06; 55(35):4982-96. PMID: 27532224.
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    73. Modi KK, Rangasamy SB, Dasarathi S, Roy A, Pahan K. Cinnamon Converts Poor Learning Mice to Good Learners: Implications for Memory Improvement. J Neuroimmune Pharmacol. 2016 12; 11(4):693-707. PMID: 27342118.
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    74. Chandra G, Rangasamy SB, Roy A, Kordower JH, Pahan K. Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease. J Biol Chem. 2016 07 15; 291(29):15267-81. PMID: 27226559.
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    75. Roy A, Rangasamy SB, Kundu M, Pahan K. BPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson's Disease. Sci Rep. 2016 Feb 26; 6:22067. PMID: 26916519.
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    76. Ghosh A, Pahan K. PPARa in lysosomal biogenesis: A perspective. Pharmacol Res. 2016 Jan; 103:144-8. PMID: 26621249.
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    77. Modi KK, Jana M, Mondal S, Pahan K. Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Upregulates Ciliary Neurotrophic Factor in Astrocytes and Oligodendrocytes. Neurochem Res. 2015 Nov; 40(11):2333-47. PMID: 26399250.
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    78. Roy A, Jana M, Kundu M, Corbett GT, Rangaswamy SB, Mishra RK, Luan CH, Gonzalez FJ, Pahan K. HMG-CoA Reductase Inhibitors Bind to PPARa to Upregulate Neurotrophin Expression in the Brain and Improve Memory in Mice. Cell Metab. 2015 Aug 04; 22(2):253-65. PMID: 26118928.
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    79. Modi KK, Roy A, Brahmachari S, Rangasamy SB, Pahan K. Cinnamon and Its Metabolite Sodium Benzoate Attenuate the Activation of p21rac and Protect Memory and Learning in an Animal Model of Alzheimer's Disease. PLoS One. 2015; 10(6):e0130398. PMID: 26102198.
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    80. Corbett GT, Gonzalez FJ, Pahan K. Activation of peroxisome proliferator-activated receptor a stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci U S A. 2015 Jul 07; 112(27):8445-50. PMID: 26080426.
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    81. Roy A, Mondal S, Kordower JH, Pahan K. Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8(+) T cells in the nigra of hemiparkinsonian monkey. Neuroscience. 2015 Aug 27; 302:36-46. PMID: 25783477.
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    82. Ghosh A, Jana M, Modi K, Gonzalez FJ, Sims KB, Berry-Kravis E, Pahan K. Activation of peroxisome proliferator-activated receptor a induces lysosomal biogenesis in brain cells: implications for lysosomal storage disorders. J Biol Chem. 2015 Apr 17; 290(16):10309-24. PMID: 25750174.
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    83. Roy A, Pahan K. PPARa signaling in the hippocampus: crosstalk between fat and memory. J Neuroimmune Pharmacol. 2015 Mar; 10(1):30-4. PMID: 25575492.
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    84. Mondal S, Pahan K. Cinnamon ameliorates experimental allergic encephalomyelitis in mice via regulatory T cells: implications for multiple sclerosis therapy. PLoS One. 2015; 10(1):e0116566. PMID: 25569428.
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    85. Rangasamy SB, Corbett GT, Roy A, Modi KK, Bennett DA, Mufson EJ, Ghosh S, Pahan K. Intranasal Delivery of NEMO-Binding Domain Peptide Prevents Memory Loss in a Mouse Model of Alzheimer's Disease. J Alzheimers Dis. 2015; 47(2):385-402. PMID: 26401561.
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    86. Pahan P, Pahan K. Can cinnamon bring aroma in Parkinson's disease treatment? Neural Regen Res. 2015 Jan; 10(1):30-2. PMID: 25788911.
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    87. Pahan K. Prospects of Cinnamon in Multiple Sclerosis. J Mult Scler (Foster City). 2015; 2(3):1000149. PMID: 26380380.
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    88. Modi KK, Jana A, Ghosh S, Watson R, Pahan K. A physically-modified saline suppresses neuronal apoptosis, attenuates tau phosphorylation and protects memory in an animal model of Alzheimer's disease. PLoS One. 2014; 9(8):e103606. PMID: 25089827.
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    89. Roy A, Modi KK, Khasnavis S, Ghosh S, Watson R, Pahan K. Enhancement of morphological plasticity in hippocampal neurons by a physically modified saline via phosphatidylinositol-3 kinase. PLoS One. 2014; 9(7):e101883. PMID: 25007337.
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    90. Khasnavis S, Pahan K. Cinnamon treatment upregulates neuroprotective proteins Parkin and DJ-1 and protects dopaminergic neurons in a mouse model of Parkinson's disease. J Neuroimmune Pharmacol. 2014 Sep; 9(4):569-81. PMID: 24946862.
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    91. Jana M, Mondal S, Jana A, Pahan K. Interleukin-12 (IL-12), but not IL-23, induces the expression of IL-7 in microglia and macrophages: implications for multiple sclerosis. Immunology. 2014 Apr; 141(4):549-63. PMID: 24224652.
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    92. Khasnavis S, Roy A, Ghosh S, Watson R, Pahan K. Protection of dopaminergic neurons in a mouse model of Parkinson's disease by a physically-modified saline containing charge-stabilized nanobubbles. J Neuroimmune Pharmacol. 2014 Mar; 9(2):218-32. PMID: 24122363.
      Citations:    
    93. Li X, Kroin JS, Kc R, Gibson G, Chen D, Corbett GT, Pahan K, Fayyaz S, Kim JS, van Wijnen AJ, Suh J, Kim SG, Im HJ. Altered spinal microRNA-146a and the microRNA-183 cluster contribute to osteoarthritic pain in knee joints. J Bone Miner Res. 2013 Dec; 28(12):2512-22. PMID: 23744481.
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    94. Roy A, Pahan K. Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's disease. FEBS Lett. 2013 Nov 01; 587(21):3567-74. PMID: 24076025.
      Citations:    
    95. Pahan K. Multiple Sclerosis and Experimental Allergic Encephalomyelitis. J Clin Cell Immunol. 2013 Sep 23; 4. PMID: 24478934.
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    96. Roy A, Jana M, Corbett GT, Ramaswamy S, Kordower JH, Gonzalez FJ, Pahan K. Regulation of cyclic AMP response element binding and hippocampal plasticity-related genes by peroxisome proliferator-activated receptor a. Cell Rep. 2013 Aug 29; 4(4):724-37. PMID: 23972989.
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    97. Roy A, Pahan K. Myelin Basic Protein-primed T Helper 2 Cells Suppress Microglial Activation via AlphaVBeta3 Integrin: Implications for Multiple Sclerosis. J Clin Cell Immunol. 2013 Aug 12; 7:158. PMID: 24575330.
      Citations:    
    98. Jana M, Pahan K. Down-regulation of Myelin Gene Expression in Human Oligodendrocytes by Nitric Oxide: Implications for Demyelination in Multiple Sclerosis. J Clin Cell Immunol. 2013 Jul 31; 4. PMID: 24273691.
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    99. Khasnavis S, Ghosh A, Roy A, Pahan K. Castration induces Parkinson disease pathologies in young male mice via inducible nitric-oxide synthase. J Biol Chem. 2013 Jul 19; 288(29):20843-20855. PMID: 23744073.
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    100. Modi KK, Sendtner M, Pahan K. Up-regulation of ciliary neurotrophic factor in astrocytes by aspirin: implications for remyelination in multiple sclerosis. J Biol Chem. 2013 Jun 21; 288(25):18533-45. PMID: 23653362.
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    101. Jana A, Modi KK, Roy A, Anderson JA, van Breemen RB, Pahan K. Up-regulation of neurotrophic factors by cinnamon and its metabolite sodium benzoate: therapeutic implications for neurodegenerative disorders. J Neuroimmune Pharmacol. 2013 Jun; 8(3):739-55. PMID: 23475543.
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    102. Corbett GT, Roy A, Pahan K. Sodium phenylbutyrate enhances astrocytic neurotrophin synthesis via protein kinase C (PKC)-mediated activation of cAMP-response element-binding protein (CREB): implications for Alzheimer disease therapy. J Biol Chem. 2013 Mar 22; 288(12):8299-8312. PMID: 23404502.
      Citations:    
    103. Miller NM, Shriver LP, Bodiga VL, Ray A, Basu S, Ahuja R, Jana A, Pahan K, Dittel BN. Lymphocytes with cytotoxic activity induce rapid microtubule axonal destabilization independently and before signs of neuronal death. ASN Neuro. 2013 Feb 06; 5(1):e00105. PMID: 23289514.
      Citations:    
    104. Mondal S, Martinson JA, Ghosh S, Watson R, Pahan K. Protection of Tregs, suppression of Th1 and Th17 cells, and amelioration of experimental allergic encephalomyelitis by a physically-modified saline. PLoS One. 2012; 7(12):e51869. PMID: 23284794.
      Citations:    
    105. Pahan K, Mondal S. Crosstalk between Nitric Oxide and T helper cells. J Clin Cell Immunol. 2012 Nov 28; 3(4). PMID: 23336087.
      Citations:    
    106. Ghosh A, Corbett GT, Gonzalez FJ, Pahan K. Gemfibrozil and fenofibrate, Food and Drug Administration-approved lipid-lowering drugs, up-regulate tripeptidyl-peptidase 1 in brain cells via peroxisome proliferator-activated receptor a: implications for late infantile Batten disease therapy. J Biol Chem. 2012 Nov 09; 287(46):38922-35. PMID: 22989886.
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    107. Jana M, Mondal S, Gonzalez FJ, Pahan K. Gemfibrozil, a lipid-lowering drug, increases myelin genes in human oligodendrocytes via peroxisome proliferator-activated receptor-?. J Biol Chem. 2012 Oct 05; 287(41):34134-48. PMID: 22879602.
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    108. Mondal S, Brahmachari S, Pahan K. Regulation of encephalitogenicity of neuroantigen-primed T cells by nitric oxide: Implications for multiple sclerosis. J Clin Cell Immunol. 2012 Jul 16; 3(3):124. PMID: 23275862.
      Citations:    
    109. Khasnavis S, Jana A, Roy A, Mazumder M, Bhushan B, Wood T, Ghosh S, Watson R, Pahan K. Suppression of nuclear factor-?B activation and inflammation in microglia by physically modified saline. J Biol Chem. 2012 Aug 24; 287(35):29529-42. PMID: 22753407.
      Citations:    
    110. Tiniakov R, Pahan K, Scrogin KE. Sympathetic innervation of the splanchnic region mediates the beneficial hemodynamic effects of 8-OH-DPAT in hemorrhagic shock. Am J Physiol Regul Integr Comp Physiol. 2012 Sep 01; 303(5):R527-38. PMID: 22718805.
      Citations:    
    111. Roy A, Ghosh A, Jana A, Liu X, Brahmachari S, Gendelman HE, Pahan K. Sodium phenylbutyrate controls neuroinflammatory and antioxidant activities and protects dopaminergic neurons in mouse models of Parkinson's disease. PLoS One. 2012; 7(6):e38113. PMID: 22723850.
      Citations:    
    112. Corbett GT, Roy A, Pahan K. Gemfibrozil, a lipid-lowering drug, upregulates IL-1 receptor antagonist in mouse cortical neurons: implications for neuronal self-defense. J Immunol. 2012 Jul 15; 189(2):1002-13. PMID: 22706077.
      Citations:    
    113. Ghosh A, Pahan K. Gemfibrozil, a lipid-lowering drug, induces suppressor of cytokine signaling 3 in glial cells: implications for neurodegenerative disorders. J Biol Chem. 2012 Aug 03; 287(32):27189-203. PMID: 22685291.
      Citations:    
    114. Mondal S, Roy A, Jana A, Ghosh S, Kordower JH, Pahan K. Testing NF-?B-based therapy in hemiparkinsonian monkeys. J Neuroimmune Pharmacol. 2012 Sep; 7(3):544-56. PMID: 22661311.
      Citations:    
    115. Jana M, Pahan K. Gemfibrozil, a lipid lowering drug, inhibits the activation of primary human microglia via peroxisome proliferator-activated receptor ?. Neurochem Res. 2012 Aug; 37(8):1718-29. PMID: 22528839.
      Citations:    
    116. Khasnavis S, Pahan K. Sodium benzoate, a metabolite of cinnamon and a food additive, upregulates neuroprotective Parkinson disease protein DJ-1 in astrocytes and neurons. J Neuroimmune Pharmacol. 2012 Jun; 7(2):424-35. PMID: 21701815.
      Citations:    
    117. Pahan K. Immunomodulation of experimental allergic encephalomyelitis by cinnamon metabolite sodium benzoate. Immunopharmacol Immunotoxicol. 2011 Dec; 33(4):586-93. PMID: 21425926.
      Citations:    
    118. Roy A, Pahan K. Prospects of statins in Parkinson disease. Neuroscientist. 2011 Jun; 17(3):244-55. PMID: 21252380.
      Citations:    
    119. Jana A, Pahan K. Fibrillar amyloid-beta-activated human astroglia kill primary human neurons via neutral sphingomyelinase: implications for Alzheimer's disease. J Neurosci. 2010 Sep 22; 30(38):12676-89. PMID: 20861373.
      Citations:    
    120. Jana A, Pahan K. Sphingolipids in multiple sclerosis. Neuromolecular Med. 2010 Dec; 12(4):351-61. PMID: 20607622.
      Citations:    
    121. Brahmachari S, Pahan K. Gender-specific expression of beta1 integrin of VLA-4 in myelin basic protein-primed T cells: implications for gender bias in multiple sclerosis. J Immunol. 2010 Jun 01; 184(11):6103-13. PMID: 20483780.
      Citations:    
    122. Pahan K. Neuroimmune pharmacological control of EAE. J Neuroimmune Pharmacol. 2010 Jun; 5(2):165-7. PMID: 20414732.
      Citations:    
    123. Brahmachari S, Pahan K. Myelin basic protein priming reduces the expression of Foxp3 in T cells via nitric oxide. J Immunol. 2010 Feb 15; 184(4):1799-809. PMID: 20083653.
      Citations:    
    124. Jana M, Dasgupta S, Pal U, Pahan K. IL-12 p40 homodimer, the so-called biologically inactive molecule, induces nitric oxide synthase in microglia via IL-12R beta 1. Glia. 2009 Nov 01; 57(14):1553-65. PMID: 19306359.
      Citations:    
    125. Ghosh A, Roy A, Matras J, Brahmachari S, Gendelman HE, Pahan K. Simvastatin inhibits the activation of p21ras and prevents the loss of dopaminergic neurons in a mouse model of Parkinson's disease. J Neurosci. 2009 Oct 28; 29(43):13543-56. PMID: 19864567.
      Citations:    
    126. Brahmachari S, Jana A, Pahan K. Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses. J Immunol. 2009 Nov 01; 183(9):5917-27. PMID: 19812204.
      Citations:    
    127. Saha RN, Ghosh A, Palencia CA, Fung YK, Dudek SM, Pahan K. TNF-alpha preconditioning protects neurons via neuron-specific up-regulation of CREB-binding protein. J Immunol. 2009 Aug 01; 183(3):2068-78. PMID: 19596989.
      Citations:    
    128. Brahmachari S, Pahan K. Suppression of regulatory T cells by IL-12p40 homodimer via nitric oxide. J Immunol. 2009 Aug 01; 183(3):2045-58. PMID: 19587012.
      Citations:    
    129. Mondal S, Roy A, Pahan K. Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis. J Immunol. 2009 Apr 15; 182(8):5013-23. PMID: 19342681.
      Citations:    
    130. Jana A, Hogan EL, Pahan K. Ceramide and neurodegeneration: susceptibility of neurons and oligodendrocytes to cell damage and death. J Neurol Sci. 2009 Mar 15; 278(1-2):5-15. PMID: 19147160.
      Citations:    
    131. Roy A, Pahan K. Gemfibrozil, stretching arms beyond lipid lowering. Immunopharmacol Immunotoxicol. 2009; 31(3):339-51. PMID: 19694602.
      Citations:    
    132. Jana M, Pahan K. IL-12 p40 homodimer, but not IL-12 p70, induces the expression of IL-16 in microglia and macrophages. Mol Immunol. 2009 Feb; 46(5):773-83. PMID: 19100623.
      Citations:    
    133. Jana M, Palencia CA, Pahan K. Fibrillar amyloid-beta peptides activate microglia via TLR2: implications for Alzheimer's disease. J Immunol. 2008 Nov 15; 181(10):7254-62. PMID: 18981147.
      Citations:    
    134. Jana M, Pahan K. Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70. Immunology. 2009 Jul; 127(3):312-25. PMID: 19019087.
      Citations:    
    135. Roy A, Jana A, Yatish K, Freidt MB, Fung YK, Martinson JA, Pahan K. Reactive oxygen species up-regulate CD11b in microglia via nitric oxide: Implications for neurodegenerative diseases. Free Radic Biol Med. 2008 Sep 01; 45(5):686-99. PMID: 18590811.
      Citations:    
    136. Dasgupta S, Bandopadhyay M, Pahan K. Generation of functional blocking monoclonal antibodies against mouse interleukin-12 p40 homodimer and monomer. Hybridoma (Larchmt). 2008 Jun; 27(3):141-51. PMID: 18582206.
      Citations:    
    137. Brahmachari S, Pahan K. Role of cytokine p40 family in multiple sclerosis. Minerva Med. 2008 Apr; 99(2):105-18. PMID: 18431321.
      Citations:    
    138. Saha RN, Jana M, Pahan K. MAPK p38 regulates transcriptional activity of NF-kappaB in primary human astrocytes via acetylation of p65. J Immunol. 2007 Nov 15; 179(10):7101-9. PMID: 17982102.
      Citations:    
    139. Ghosh A, Roy A, Liu X, Kordower JH, Mufson EJ, Hartley DM, Ghosh S, Mosley RL, Gendelman HE, Pahan K. Selective inhibition of NF-kappaB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A. 2007 Nov 20; 104(47):18754-9. PMID: 18000063.
      Citations:    
    140. Jana M, Jana A, Liu X, Ghosh S, Pahan K. Involvement of phosphatidylinositol 3-kinase-mediated up-regulation of I kappa B alpha in anti-inflammatory effect of gemfibrozil in microglia. J Immunol. 2007 Sep 15; 179(6):4142-52. PMID: 17785853.
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    141. Roy A, Liu X, Pahan K. Myelin basic protein-primed T cells induce neurotrophins in glial cells via alphavbeta3 [corrected] integrin. J Biol Chem. 2007 Nov 02; 282(44):32222-32. PMID: 17823123.
      Citations:    
    142. Dasgupta S, Roy A, Jana M, Hartley DM, Pahan K. Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Mol Pharmacol. 2007 Oct; 72(4):934-46. PMID: 17625103.
      Citations:    
    143. Brahmachari S, Pahan K. Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis. J Immunol. 2007 Jul 01; 179(1):275-83. PMID: 17579047.
      Citations:    
    144. Jana M, Jana A, Pal U, Pahan K. A simplified method for isolating highly purified neurons, oligodendrocytes, astrocytes, and microglia from the same human fetal brain tissue. Neurochem Res. 2007 Dec; 32(12):2015-22. PMID: 17447141.
      Citations:    
    145. Saha RN, Pahan K. Differential regulation of Mn-superoxide dismutase in neurons and astroglia by HIV-1 gp120: Implications for HIV-associated dementia. Free Radic Biol Med. 2007 Jun 15; 42(12):1866-78. PMID: 17512466.
      Citations:    
    146. Jana A, Pahan K. Oxidative stress kills human primary oligodendrocytes via neutral sphingomyelinase: implications for multiple sclerosis. J Neuroimmune Pharmacol. 2007 Jun; 2(2):184-93. PMID: 18040843.
      Citations:    
    147. Saha RN, Pahan K. Signals for the induction of nitric oxide synthase in astrocytes. Neurochem Int. 2006 Jul; 49(2):154-63. PMID: 16740341.
      Citations:    
    148. Saha RN, Liu X, Pahan K. Up-regulation of BDNF in astrocytes by TNF-alpha: a case for the neuroprotective role of cytokine. J Neuroimmune Pharmacol. 2006 Sep; 1(3):212-22. PMID: 18040799.
      Citations:    
    149. Brahmachari S, Fung YK, Pahan K. Induction of glial fibrillary acidic protein expression in astrocytes by nitric oxide. J Neurosci. 2006 May 03; 26(18):4930-9. PMID: 16672668.
      Citations:    
    150. Saha RN, Pahan K. Regulation of inducible nitric oxide synthase gene in glial cells. Antioxid Redox Signal. 2006 May-Jun; 8(5-6):929-47. PMID: 16771683.
      Citations:    
    151. Pahan K. Lipid-lowering drugs. Cell Mol Life Sci. 2006 May; 63(10):1165-78. PMID: 16568248.
      Citations:    
    152. Saha RN, Pahan K. HATs and HDACs in neurodegeneration: a tale of disconcerted acetylation homeostasis. Cell Death Differ. 2006 Apr; 13(4):539-50. PMID: 16167067.
      Citations:    
    153. Roy A, Fung YK, Liu X, Pahan K. Up-regulation of microglial CD11b expression by nitric oxide. J Biol Chem. 2006 May 26; 281(21):14971-80. PMID: 16551637.
      Citations:    
    154. Jana M, Pahan K. Redox regulation of cytokine-mediated inhibition of myelin gene expression in human primary oligodendrocytes. Free Radic Biol Med. 2005 Sep 15; 39(6):823-31. PMID: 16109311.
      Citations:    
    155. Dasgupta S, Jana M, Liu X, Pahan K. Myelin basic protein-primed T cells of female but not male mice induce nitric-oxide synthase and proinflammatory cytokines in microglia: implications for gender bias in multiple sclerosis. J Biol Chem. 2005 Sep 23; 280(38):32609-17. PMID: 16046404.
      Citations:    
    156. Jana M, Anderson JA, Saha RN, Liu X, Pahan K. Regulation of inducible nitric oxide synthase in proinflammatory cytokine-stimulated human primary astrocytes. Free Radic Biol Med. 2005 Mar 01; 38(5):655-64. PMID: 15683721.
      Citations:    
    157. Jana A, Pahan K. Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase. J Neurosci. 2004 Oct 27; 24(43):9531-40. PMID: 15509740.
      Citations:    
    158. Jana A, Pahan K. Fibrillar amyloid-beta peptides kill human primary neurons via NADPH oxidase-mediated activation of neutral sphingomyelinase. Implications for Alzheimer's disease. J Biol Chem. 2004 Dec 03; 279(49):51451-9. PMID: 15452132.
      Citations:    
    159. Dasgupta S, Jana M, Zhou Y, Fung YK, Ghosh S, Pahan K. Antineuroinflammatory effect of NF-kappaB essential modifier-binding domain peptides in the adoptive transfer model of experimental allergic encephalomyelitis. J Immunol. 2004 Jul 15; 173(2):1344-54. PMID: 15240729.
      Citations:    
    160. Auch CJ, Saha RN, Sheikh FG, Liu X, Jacobs BL, Pahan K. Role of protein kinase R in double-stranded RNA-induced expression of nitric oxide synthase in human astroglia. FEBS Lett. 2004 Apr 09; 563(1-3):223-8. PMID: 15063753.
      Citations:    
    161. Saha RN, Pahan K. Tumor necrosis factor-alpha at the crossroads of neuronal life and death during HIV-associated dementia. J Neurochem. 2003 Sep; 86(5):1057-71. PMID: 12911614.
      Citations:    
    162. Jana M, Dasgupta S, Saha RN, Liu X, Pahan K. Induction of tumor necrosis factor-alpha (TNF-alpha) by interleukin-12 p40 monomer and homodimer in microglia and macrophages. J Neurochem. 2003 Jul; 86(2):519-28. PMID: 12871593.
      Citations:    
    163. Dasgupta S, Jana M, Liu X, Pahan K. Role of very-late antigen-4 (VLA-4) in myelin basic protein-primed T cell contact-induced expression of proinflammatory cytokines in microglial cells. J Biol Chem. 2003 Jun 20; 278(25):22424-31. PMID: 12690109.
      Citations:    
    164. Dasgupta S, Zhou Y, Jana M, Banik NL, Pahan K. Sodium phenylacetate inhibits adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice at multiple steps. J Immunol. 2003 Apr 01; 170(7):3874-82. PMID: 12646656.
      Citations:    
    165. Pahan K, Jana M, Liu X, Taylor BS, Wood C, Fischer SM. Gemfibrozil, a lipid-lowering drug, inhibits the induction of nitric-oxide synthase in human astrocytes. J Biol Chem. 2002 Nov 29; 277(48):45984-91. PMID: 12244038.
      Citations:    
    166. Dasgupta S, Jana M, Liu X, Pahan K. Myelin basic protein-primed T cells induce nitric oxide synthase in microglial cells. Implications for multiple sclerosis. J Biol Chem. 2002 Oct 18; 277(42):39327-33. PMID: 12176974.
      Citations:    
    167. Liu X, Jana M, Dasgupta S, Koka S, He J, Wood C, Pahan K. Human immunodeficiency virus type 1 (HIV-1) tat induces nitric-oxide synthase in human astroglia. J Biol Chem. 2002 Oct 18; 277(42):39312-9. PMID: 12167619.
      Citations:    
    168. Webb SJ, McPherson JR, Pahan K, Koka S. Regulation of TNF-alpha-induced IL-6 production in MG-63 human osteoblast-like cells. J Dent Res. 2002 Jan; 81(1):17-22. PMID: 11820362.
      Citations:    
    169. Jana M, Dasgupta S, Liu X, Pahan K. Regulation of tumor necrosis factor-alpha expression by CD40 ligation in BV-2 microglial cells. J Neurochem. 2002 Jan; 80(1):197-206. PMID: 11796758.
      Citations:    
    170. Jana M, Liu X, Koka S, Ghosh S, Petro TM, Pahan K. Ligation of CD40 stimulates the induction of nitric-oxide synthase in microglial cells. J Biol Chem. 2001 Nov 30; 276(48):44527-33. PMID: 11551948.
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    171. Pahan K, Sheikh FG, Liu X, Hilger S, McKinney M, Petro TM. Induction of nitric-oxide synthase and activation of NF-kappaB by interleukin-12 p40 in microglial cells. J Biol Chem. 2001 Mar 16; 276(11):7899-905. PMID: 11110796.
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    172. Pahan K, Khan M, Singh I. Interleukin-10 and interleukin-13 inhibit proinflammatory cytokine-induced ceramide production through the activation of phosphatidylinositol 3-kinase. J Neurochem. 2000 Aug; 75(2):576-82. PMID: 10899932.
      Citations:    
    173. Pahan K, Schmid M. Activation of nuclear factor-kB in the spinal cord of experimental allergic encephalomyelitis. Neurosci Lett. 2000 Jun 16; 287(1):17-20. PMID: 10841980.
      Citations:    
    174. Pahan K, Liu X, McKinney MJ, Wood C, Sheikh FG, Raymond JR. Expression of a dominant-negative mutant of p21(ras) inhibits induction of nitric oxide synthase and activation of nuclear factor-kappaB in primary astrocytes. J Neurochem. 2000 Jun; 74(6):2288-95. PMID: 10820188.
      Citations:    
    175. Pahan K, Liu X, Wood C, Raymond JR. Expression of a constitutively active form of phosphatidylinositol 3-kinase inhibits the induction of nitric oxide synthase in human astrocytes. FEBS Lett. 2000 Apr 28; 472(2-3):203-7. PMID: 10788611.
      Citations:    
    176. Pahan K, Dobashi K, Ghosh B, Singh I. Induction of the manganese superoxide dismutase gene by sphingomyelinase and ceramide. J Neurochem. 1999 Aug; 73(2):513-20. PMID: 10428046.
      Citations:    
    177. Stanislaus R, Pahan K, Singh AK, Singh I. Amelioration of experimental allergic encephalomyelitis in Lewis rats by lovastatin. Neurosci Lett. 1999 Jul 09; 269(2):71-4. PMID: 10430507.
      Citations:    
    178. Pahan K, Raymond JR, Singh I. Inhibition of phosphatidylinositol 3-kinase induces nitric-oxide synthase in lipopolysaccharide- or cytokine-stimulated C6 glial cells. J Biol Chem. 1999 Mar 12; 274(11):7528-36. PMID: 10066820.
      Citations:    
    179. Singh I, Pahan K, Khan M, Singh AK. Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases. J Biol Chem. 1998 Aug 07; 273(32):20354-62. PMID: 9685387.
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    180. Khan M, Pahan K, Singh AK, Singh I. Cytokine-induced accumulation of very long-chain fatty acids in rat C6 glial cells: implication for X-adrenoleukodystrophy. J Neurochem. 1998 Jul; 71(1):78-87. PMID: 9648853.
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    181. Pahan K, Sheikh FG, Namboodiri AM, Singh I. Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages. J Biol Chem. 1998 May 15; 273(20):12219-26. PMID: 9575170.
      Citations:    
    182. Pahan K, Khan M, Singh I. Therapy for X-adrenoleukodystrophy: normalization of very long chain fatty acids and inhibition of induction of cytokines by cAMP. J Lipid Res. 1998 May; 39(5):1091-100. PMID: 9610777.
      Citations:    
    183. Singh I, Pahan K, Khan M. Lovastatin and sodium phenylacetate normalize the levels of very long chain fatty acids in skin fibroblasts of X- adrenoleukodystrophy. FEBS Lett. 1998 Apr 24; 426(3):342-6. PMID: 9600263.
      Citations:    
    184. Sheikh FG, Pahan K, Khan M, Barbosa E, Singh I. Abnormality in catalase import into peroxisomes leads to severe neurological disorder. Proc Natl Acad Sci U S A. 1998 Mar 17; 95(6):2961-6. PMID: 9501198.
      Citations:    
    185. Pahan K, Sheikh FG, Khan M, Namboodiri AM, Singh I. Sphingomyelinase and ceramide stimulate the expression of inducible nitric-oxide synthase in rat primary astrocytes. J Biol Chem. 1998 Jan 30; 273(5):2591-600. PMID: 9446561.
      Citations:    
    186. Pahan K, Sheikh FG, Namboodiri AM, Singh I. N-acetyl cysteine inhibits induction of no production by endotoxin or cytokine stimulated rat peritoneal macrophages, C6 glial cells and astrocytes. Free Radic Biol Med. 1998 Jan 01; 24(1):39-48. PMID: 9436612.
      Citations:    
    187. Pahan K, Sheikh FG, Namboodiri AM, Singh I. Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, microglia, and macrophages. J Clin Invest. 1997 Dec 01; 100(11):2671-9. PMID: 9389730.
      Citations:    
    188. Dobashi K, Pahan K, Chahal A, Singh I. Modulation of endogenous antioxidant enzymes by nitric oxide in rat C6 glial cells. J Neurochem. 1997 May; 68(5):1896-903. PMID: 9109515.
      Citations:    
    189. Pahan K, Namboodiri AM, Sheikh FG, Smith BT, Singh I. Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes. J Biol Chem. 1997 Mar 21; 272(12):7786-91. PMID: 9065441.
      Citations:    
    190. Gachhui R, Chaudhuri J, Ray S, Pahan K, Mandal A. Studies on mercury-detoxicating enzymes from a broad-spectrum mercury-resistant strain of Flavobacterium rigense. Folia Microbiol (Praha). 1997; 42(4):337-43. PMID: 9527517.
      Citations:    
    191. Pahan K, Smith BT, Singh AK, Singh I. Cytochrome P-450 2E1 in rat liver peroxisomes: downregulation by ischemia/reperfusion-induced oxidative stress. Free Radic Biol Med. 1997; 23(7):963-71. PMID: 9358238.
      Citations:    
    192. Pahan K, Khan M, Singh I. Phytanic acid oxidation: normal activation and transport yet defective alpha-hydroxylation of phytanic acid in peroxisomes from Refsum disease and rhizomelic chondrodysplasia punctata. J Lipid Res. 1996 May; 37(5):1137-43. PMID: 8725164.
      Citations:    
    193. Burdette DE, Kremser K, Fink JK, Pahan K, Stanley W, Singh I. Late-onset generalized disorder of peroxisomes. Neurology. 1996 Mar; 46(3):829-31. PMID: 8618694.
      Citations:    
    194. Pahan K, Smith BT, Singh I. Epoxide hydrolase in human and rat peroxisomes: implication for disorders of peroxisomal biogenesis. J Lipid Res. 1996 Jan; 37(1):159-67. PMID: 8820111.
      Citations:    
    195. Pahan K, Khan M, Smith BT, Singh I. Ketoconazole and other imidazole derivatives are potent inhibitors of peroxisomal phytanic acid alpha-oxidation. FEBS Lett. 1995 Dec 18; 377(2):213-6. PMID: 8543053.
      Citations:    
    196. Kremser K, Stangl H, Pahan K, Singh I. Nitric oxide regulates peroxisomal enzyme activities. Eur J Clin Chem Clin Biochem. 1995 Nov; 33(11):763-74. PMID: 8620052.
      Citations:    
    197. Pahan K, Chaudhuri J, Ghosh D, Gachhui R, Ray S, Mandal A. Enhanced elimination of HgCl2 from natural water by a broad-spectrum Hg-resistant Bacillus pasteurii strain DR2 in presence of benzene. Bull Environ Contam Toxicol. 1995 Oct; 55(4):554-61. PMID: 8555680.
      Citations:    
    198. Pahan K, Singh I. Phytanic acid oxidation: topographical localization of phytanoyl-CoA ligase and transport of phytanic acid into human peroxisomes. J Lipid Res. 1995 May; 36(5):986-97. PMID: 7544821.
      Citations:    
    199. Pahan K, Gulati S, Singh I. Phytanic acid alpha-oxidation in rat liver mitochondria. Biochim Biophys Acta. 1994 Dec 15; 1201(3):491-7. PMID: 7803482.
      Citations:    
    200. Pahan K, Ghosh DK, Ray S, Gachhui R, Chaudhuri J, Mandal A. Mercury and organomercurial degrading enzymes in a broad-spectrum Hg-resistant strain of Bacillus pasteurii. Bull Environ Contam Toxicol. 1994 Apr; 52(4):582-9. PMID: 8167453.
      Citations:    
    201. Pahan K, Singh I. Intraorganellar localization of CoASH-independent phytanic acid oxidation in human liver peroxisomes. FEBS Lett. 1993 Oct 25; 333(1-2):154-8. PMID: 8224157.
      Citations:    
    202. Singh I, Pahan K, Singh AK, Barbosa E. Refsum disease: a defect in the alpha-oxidation of phytanic acid in peroxisomes. J Lipid Res. 1993 Oct; 34(10):1755-64. PMID: 7504046.
      Citations:    
    203. Singh I, Pahan K, Dhaunsi GS, Lazo O, Ozand P. Phytanic acid alpha-oxidation. Differential subcellular localization in rat and human tissues and its inhibition by nycodenz. J Biol Chem. 1993 May 15; 268(14):9972-9. PMID: 8486724.
      Citations:    
    204. Pahan K, Cofer J, Baliga P, Singh I. Identification of phytanoyl-CoA ligase as a distinct acyl-CoA ligase in peroxisomes from cultured human skin fibroblasts. FEBS Lett. 1993 May 10; 322(2):101-4. PMID: 8482375.
      Citations:    
    205. Pahan K, Ray S, Gachhui R, Chaudhuri J, Mandal A. Heat sensitivity of mercuric ion and organomercurial degrading enzymes of aquatic, mercury-resistant bacteria. World J Microbiol Biotechnol. 1993 Mar; 9(2):180-3. PMID: 24419942.
      Citations:    
    206. Ray S, Pahan K, Gachhui R, Chaudhuri J, Mandal A. Studies on the mercury volatilizing enzymes in nitrogen-fixing Beijerinckia mobilis. World J Microbiol Biotechnol. 1993 Mar; 9(2):184-6. PMID: 24419943.
      Citations:    
    207. Pahan K, Gachhui R, Ray S, Chaudhuri J, Mandal A. Bacterial degradation and utilization of merbromine and fluorescein mercuric acetate. Bull Environ Contam Toxicol. 1992 Mar; 48(3):421-7. PMID: 1378330.
      Citations:    
    208. Pahan K, Gachhui R, Ray S, Chaudhuri J, Mandal A. A PMA degrading constitutive organomercurial lyase in a broad-spectrum mercury resistant Bacillus pasteurii strain DR2. Indian J Exp Biol. 1991 Dec; 29(12):1147-9. PMID: 1816104.
      Citations:    
    209. Pahan K, Ray S, Gachhui R, Chaudhuri J, Mandal A. Volatilization of mercury compounds and utilization of various aromatic compounds by a broad-spectrum mercury resistant Bacillus pasteurii strain. Bull Environ Contam Toxicol. 1991 Apr; 46(4):591-8. PMID: 1855005.
      Citations:    
    210. Gachhui R, Pahan K, Ray S, Chaudhuri J, Mandal A. Cell free glutathione synthesizing activity of mercury resistant bacteria. Bull Environ Contam Toxicol. 1991 Mar; 46(3):336-42. PMID: 2031999.
      Citations:    
    211. Pahan K, Ray S, Gachhui R, Chaudhuri J, Mandal A. Effect of thiol compounds and flavins on mercury and organomercurial degrading enzymes in mercury resistant aquatic bacteria. Bull Environ Contam Toxicol. 1990 Feb; 44(2):216-23. PMID: 2322662.
      Citations:    
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