"rhoA GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A RHO GTP-BINDING PROTEIN involved in regulating signal transduction pathways that control assembly of focal adhesions and actin stress fibers. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020742
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.700.200 D12.644.360.525.700.200 D12.776.157.325.515.700.200 D12.776.476.525.700.200
|
| Concept/Terms |
rhoA GTP-Binding Protein- rhoA GTP-Binding Protein
- GTP-Binding Protein, rhoA
- rhoA GTP Binding Protein
- rhoA P21 Protein
- rho12 Protein
- ARHA GTP-Binding Protein
- ARHA GTP Binding Protein
- GTP-Binding Protein, ARHA
- rhoA Protein
- Ras Homolog Family Member A
- rho12 GTP-Binding Protein
- GTP-Binding Protein, rho12
- rho12 GTP Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "rhoA GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "rhoA GTP-Binding Protein".
This graph shows the total number of publications written about "rhoA GTP-Binding Protein" by people in this website by year, and whether "rhoA GTP-Binding Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 1 | 0 | 1 |
| 2009 | 2 | 1 | 3 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "rhoA GTP-Binding Protein" by people in Profiles.
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Podocyte Integrin-?3 and Activated Protein C Coordinately Restrict RhoA Signaling and Ameliorate Diabetic Nephropathy. J Am Soc Nephrol. 2020 08; 31(8):1762-1780.
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Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. J Am Soc Nephrol. 2017 02; 28(2):446-451.
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Sphingomyelinase-like phosphodiesterase 3b expression levels determine podocyte injury phenotypes in glomerular disease. J Am Soc Nephrol. 2015 Jan; 26(1):133-47.
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Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities. Am J Physiol Lung Cell Mol Physiol. 2013 Aug 15; 305(4):L291-300.
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Podocyte GTPases regulate kidney filter dynamics. Kidney Int. 2012 Jun; 81(11):1053-5.
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Distinct roles for Rho versus Rac/Cdc42 GTPases downstream of Vav2 in regulating mammary epithelial acinar architecture. J Biol Chem. 2010 Jan 08; 285(2):1555-68.
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LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs. Circ Res. 2009 Sep 11; 105(6):549-56.
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Overexpression of RhoA induces preneoplastic transformation of primary mammary epithelial cells. Cancer Res. 2009 Jan 15; 69(2):483-91.
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Phosphorylation of GTP dissociation inhibitor by PKA negatively regulates RhoA. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1161-8.
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RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circ Res. 2007 Jul 06; 101(1):50-8.