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Dan N Predescu

TitleAssistant Professor
InstitutionRush University, Rush Medical College
DepartmentPulmonary, Critical Care and Sleep Medicine
Address
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    My Scopus ID is 6701639380.
    My NIH COMMONS name is DPREDESCU.

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Predescu D, Qin S, Stefanis V, Carman B, Ganesh B, Sharma K, Mokhlesi B, Predescu S. RUNX1 mediates the therapeutic effects of mesenchymal stem cells-derived microparticles in acute respiratory distress syndrome. Clin Transl Med. 2023 Nov; 13(11):e1455. PMID: 37955231.
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    2. Predescu DN, Mokhlesi B, Predescu SA. The Impact of Sex Chromosomes in the Sexual Dimorphism of Pulmonary Arterial Hypertension. Am J Pathol. 2022 04; 192(4):582-594. PMID: 35114193.
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    3. Qin S, Predescu D, Carman B, Patel P, Chen J, Kim M, Lahm T, Geraci M, Predescu SA. Up-Regulation of the Long Noncoding RNA X-Inactive-Specific Transcript and the Sex Bias in Pulmonary Arterial Hypertension. Am J Pathol. 2021 06; 191(6):1135-1150. PMID: 33836164.
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    4. Shah TG, Predescu D, Predescu S. Mesenchymal stem cells-derived extracellular vesicles in acute respiratory distress syndrome: a review of current literature and potential future treatment options. Clin Transl Med. 2019 Sep 12; 8(1):25. PMID: 31512000.
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    5. Carman BL, Predescu DN, Machado R, Predescu SA. Plexiform Arteriopathy in Rodent Models of Pulmonary Arterial Hypertension. Am J Pathol. 2019 06; 189(6):1133-1144. PMID: 30926336.
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    6. Jeganathan N, Predescu D, Predescu S. Intersectin-1s deficiency in pulmonary pathogenesis. Respir Res. 2017 09 06; 18(1):168. PMID: 28874189.
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    7. Chan DD, Li J, Luo W, Predescu DN, Cole BJ, Plaas A. Pirfenidone reduces subchondral bone loss and fibrosis after murine knee cartilage injury. J Orthop Res. 2018 01; 36(1):365-376. PMID: 28646530.
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    8. Predescu SA, Zhang J, Bardita C, Patel M, Godbole V, Predescu DN. Mouse Lung Fibroblast Resistance to Fas-Mediated Apoptosis Is Dependent on the Baculoviral Inhibitor of Apoptosis Protein 4 and the Cellular FLICE-Inhibitory Protein. Front Physiol. 2017; 8:128. PMID: 28352235.
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    9. Patel M, Predescu D, Bardita C, Chen J, Jeganathan N, Pritchard M, DiBartolo S, Machado R, Predescu S. Modulation of Intersectin-1s Lung Expression Induces Obliterative Remodeling and Severe Plexiform Arteriopathy in the Murine Pulmonary Vascular Bed. Am J Pathol. 2017 Mar; 187(3):528-542. PMID: 28068512.
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    10. Tran KA, Zhang X, Predescu D, Huang X, Machado RF, G?thert JR, Malik AB, Valyi-Nagy T, Zhao YY. Endothelial ?-Catenin Signaling Is Required for Maintaining Adult Blood-Brain Barrier Integrity and Central Nervous System Homeostasis. Circulation. 2016 Jan 12; 133(2):177-86. PMID: 26538583.
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    11. Lockett AD, Petrusca DN, Justice MJ, Poirier C, Serban KA, Rush NI, Kamocka M, Predescu D, Predescu S, Petrache I. Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15; 309(4):L425-34. PMID: 26092999.
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    12. Bardita C, Predescu DN, Sha F, Patel M, Balaji G, Predescu SA. Endocytic deficiency induced by ITSN-1s knockdown alters the Smad2/3-Erk1/2 signaling balance downstream of Alk5. J Cell Sci. 2015 Apr 15; 128(8):1528-41. PMID: 25720380.
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    13. Predescu S, Knezevic I, Bardita C, Neamu RF, Brovcovych V, Predescu D. Platelet activating factor-induced ceramide micro-domains drive endothelial NOS activation and contribute to barrier dysfunction. PLoS One. 2013; 8(9):e75846. PMID: 24086643.
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    14. Patel M, Predescu D, Tandon R, Bardita C, Pogoriler J, Bhorade S, Wang M, Comhair S, Ryan-Hemnes A, Chen J, Machado R, Husain A, Erzurum S, Predescu S. A novel p38 mitogen-activated protein kinase/Elk-1 transcription factor-dependent molecular mechanism underlying abnormal endothelial cell proliferation in plexogenic pulmonary arterial hypertension. J Biol Chem. 2013 Sep 06; 288(36):25701-25716. PMID: 23893408.
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    15. Bardita C, Predescu D, Predescu S. Long-term silencing of intersectin-1s in mouse lungs by repeated delivery of a specific siRNA via cationic liposomes. Evaluation of knockdown effects by electron microscopy. J Vis Exp. 2013 Jun 21; (76). PMID: 23851900.
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    16. Predescu DN, Neamu R, Bardita C, Wang M, Predescu SA. Impaired caveolae function and upregulation of alternative endocytic pathways induced by experimental modulation of intersectin-1s expression in mouse lung endothelium. Biochem Res Int. 2012; 2012:672705. PMID: 22506115.
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    17. Knezevic I, Predescu D, Bardita C, Wang M, Sharma T, Keith B, Neamu R, Malik AB, Predescu S. Regulation of dynamin-2 assembly-disassembly and function through the SH3A domain of intersectin-1s. J Cell Mol Med. 2011 Nov; 15(11):2364-76. PMID: 21129155.
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    18. Gorovoy M, Neamu R, Niu J, Vogel S, Predescu D, Miyoshi J, Takai Y, Kini V, Mehta D, Malik AB, Voyno-Yasenetskaya T. RhoGDI-1 modulation of the activity of monomeric RhoGTPase RhoA regulates endothelial barrier function in mouse lungs. Circ Res. 2007 Jul 06; 101(1):50-8. PMID: 17525371.
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    19. Miyawaki-Shimizu K, Predescu D, Shimizu J, Broman M, Predescu S, Malik AB. siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L405-13. PMID: 16183667.
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    20. Predescu D, Predescu S, Shimizu J, Miyawaki-Shimizu K, Malik AB. Constitutive eNOS-derived nitric oxide is a determinant of endothelial junctional integrity. Am J Physiol Lung Cell Mol Physiol. 2005 Sep; 289(3):L371-81. PMID: 16093363.
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    21. Gao XP, Liu Q, Broman M, Predescu D, Frey RS, Malik AB. Inactivation of CD11b in a mouse transgenic model protects against sepsis-induced lung PMN infiltration and vascular injury. Physiol Genomics. 2005 Apr 14; 21(2):230-42. PMID: 15831844.
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    22. Predescu SA, Predescu DN, Timblin BK, Stan RV, Malik AB. Intersectin regulates fission and internalization of caveolae in endothelial cells. Mol Biol Cell. 2003 Dec; 14(12):4997-5010. PMID: 12960435.
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