"Proto-Oncogene Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				Products of proto-oncogenes. Normally they do not have oncogenic or transforming properties, but are involved in the regulation or differentiation of cell growth. They often have protein kinase activity.
    
			
			
				
				
					
						| Descriptor ID | 
										
							D011518
						 | 			
					
					
						| MeSH Number(s) | 
						
							 D12.776.624.664.700 
						 | 
					
					
						| Concept/Terms | 
						
							Proto-Oncogene Proteins- Proto-Oncogene Proteins
 - Proto Oncogene Proteins
 - Proto-Oncogene Products, Cellular
 - Cellular Proto-Oncogene Products
 - Proto Oncogene Products, Cellular
 - Proto Oncogene Proteins, Cellular
 - c-onc Proteins
 - c onc Proteins
 - Cellular Proto-Oncogene Proteins
 - Cellular Proto Oncogene Proteins
 - Proto-Oncogene Proteins, Cellular
 
  
						 | 
					
					
				
			 
			
				Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Proto-Oncogene Proteins" by people in this website by year, and whether "Proto-Oncogene Proteins" was a major or minor topic of these publications. 
				
					
                    To see the data from this visualization as text, 
click here. 
				 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1996 | 1 | 0 | 1 | 
| 1997 | 1 | 0 | 1 | 
| 1999 | 2 | 1 | 3 | 
| 2000 | 2 | 0 | 2 | 
| 2001 | 3 | 1 | 4 | 
| 2002 | 0 | 1 | 1 | 
| 2003 | 3 | 1 | 4 | 
| 2004 | 2 | 1 | 3 | 
| 2005 | 1 | 3 | 4 | 
| 2009 | 1 | 0 | 1 | 
| 2011 | 0 | 1 | 1 | 
| 2013 | 1 | 0 | 1 | 
| 2014 | 0 | 1 | 1 | 
| 2017 | 1 | 1 | 2 | 
| 2019 | 0 | 2 | 2 | 
| 2020 | 1 | 0 | 1 | 
| 2021 | 1 | 0 | 1 | 
| 2022 | 1 | 0 | 1 | 
                    To return to the timeline, 
click here.
                 
			 	
			
			
			
			
				Below are the most recent publications written about "Proto-Oncogene Proteins" by people in Profiles.
						
					
								- 
								
Loss of MEN1 function impairs DNA repair capability of pancreatic neuroendocrine tumors. Endocr Relat Cancer. 2022 03 21; 29(4):225-239.
															
								 
							
								- 
								
Analysis of Gene Expression Patterns of Epigenetic Enzymes Dnmt3a, Tet1 and Ogt in Murine Chondrogenic Models. Cells. 2021 10 06; 10(10).
															
								 
							
								- 
								
Epigenomic analysis of Parkinson's disease neurons identifies Tet2 loss as neuroprotective. Nat Neurosci. 2020 10; 23(10):1203-1214.
															
								 
							
								- 
								
Ewing-like sarcomas: New molecular diagnoses in need of optimized treatment approaches. Indian J Med Res. 2019 12; 150(6):521-523.
															
								 
							
								- 
								
Distinct genome-wide methylation patterns in sporadic and hereditary nonfunctioning pancreatic neuroendocrine tumors. Cancer. 2019 04 15; 125(8):1247-1257.
															
								 
							
								- 
								
Screening for Lynch Syndrome in Cases with Colorectal Carcinoma from Mashhad. Arch Iran Med. 2017 Jun; 20(6):332-337.
															
								 
							
								- 
								
Overexpression of lipid metabolism genes and PBX1 in the contralateral breasts of women with estrogen receptor-negative breast cancer. Int J Cancer. 2017 06 01; 140(11):2484-2497.
															
								 
							
								- 
								
Pseudomonas aeruginosa ExoT Induces Mitochondrial Apoptosis in Target Host Cells in a Manner That Depends on Its GTPase-activating Protein (GAP) Domain Activity. J Biol Chem. 2015 Nov 27; 290(48):29063-73.
															
								 
							
								- 
								
Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study. Clin Cancer Res. 2014 Sep 15; 20(18):4962-70.
															
								 
							
								- 
								
Single copies of mutant KRAS and mutant PIK3CA cooperate in immortalized human epithelial cells to induce tumor formation. Cancer Res. 2013 Jun 01; 73(11):3248-61.