"Cyclin D1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.
| Descriptor ID |
D019938
|
| MeSH Number(s) |
D12.644.360.262.150.100 D12.776.167.218.150.100 D12.776.476.262.150.100 D12.776.624.664.700.100
|
| Concept/Terms |
Cyclin D1- Cyclin D1
- Proto-Oncogene Products bcl-1
- Proto Oncogene Products bcl 1
- Proto-Oncogene Protein bcl-1
- Proto Oncogene Protein bcl 1
- bcl-1, Proto-Oncogene Protein
- bcl-1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl-1
- bcl 1 Proto Oncogene Proteins
- CCND1 Protein
- PRAD1 Protein
- bcl-1 Proto-Oncogene Products
- Proto-Oncogene Products, bcl-1
- bcl 1 Proto Oncogene Products
- bcl1 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl1
- bcl1 Proto Oncogene Proteins
- Proto-Oncogene Proteins c-bcl-1
- Proto Oncogene Proteins c bcl 1
- c-bcl-1, Proto-Oncogene Proteins
- c-bcl-1 Proteins
- c bcl 1 Proteins
|
Below are MeSH descriptors whose meaning is more general than "Cyclin D1".
Below are MeSH descriptors whose meaning is more specific than "Cyclin D1".
This graph shows the total number of publications written about "Cyclin D1" by people in this website by year, and whether "Cyclin D1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclin D1" by people in Profiles.
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The growth response to androgen receptor signaling in ERa-negative human breast cells is dependent on p21 and mediated by MAPK activation. Breast Cancer Res. 2012 Feb 09; 14(1):R27.
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Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysis. Mod Pathol. 2006 Jul; 19(7):999-1009.
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Involvement of cyclin D1 and E2F1 in intramedullary apoptosis in myelodysplastic syndromes. J Hematother Stem Cell Res. 2003 Aug; 12(4):443-50.
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Abnormalities of molecular regulators of proliferation and apoptosis in carcinoma of the oral cavity and oropharynx. Auris Nasus Larynx. 2002 Apr; 29(2):165-74.
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Regulators of proliferation and apoptosis in carcinoma of the larynx. Laryngoscope. 1998 May; 108(5):630-8.
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Cyclin D1 expression in squamous cell carcinomas of the head and neck and in oral mucosa in relation to proliferation and apoptosis. Clin Cancer Res. 1997 Jan; 3(1):95-101.