"Zinc Finger Protein GLI1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional activator and oncogene protein that contains two CYS2-HIS2 ZINC FINGERS. Two isoforms are expressed; both regulate the expression of specific genes during development of craniofacial features, digits, the CENTRAL NERVOUS SYSTEM; and the GASTROINTESTINAL TRACT. They also regulate SONIC HEDGEHOG PROTEIN signaling and cell proliferation.
Descriptor ID |
D000071676
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MeSH Number(s) |
D12.776.260.755.850 D12.776.624.664.700.989 D12.776.930.900.700
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Concept/Terms |
Zinc Finger Protein GLI1- Zinc Finger Protein GLI1
- Oncogene GLI Protein
- GLI Protein, Oncogene
- Glioma-Associated Oncogene Protein
- Glioma Associated Oncogene Protein
- Oncogene Protein, Glioma-Associated
- Gli Protein
- Gli1 Protein
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Below are MeSH descriptors whose meaning is more general than "Zinc Finger Protein GLI1".
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This graph shows the total number of publications written about "Zinc Finger Protein GLI1" by people in this website by year, and whether "Zinc Finger Protein GLI1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Zinc Finger Protein GLI1" by people in Profiles.
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Activation of the Sonic Hedgehog pathway in thyroid neoplasms and its potential role in tumor cell proliferation. Endocr Relat Cancer. 2012 Apr; 19(2):167-79.
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Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes. Proc Natl Acad Sci U S A. 2007 Sep 04; 104(36):14466-71.