"Wnt-5a Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A Wnt protein and ligand for FRIZZLED RECEPTORS that may function as an inhibitor or activator of the WNT SIGNALING PATHWAY. For example, it activates signaling in the presence of Frizzled-4 but is inhibitory when coupled with ROR2 TYROSINE KINASE. It is required for axis formation during EMBRYOGENESIS and inhibits the proliferation, migration, and invasiveness of cancer cells.
Descriptor ID |
D000071818
|
MeSH Number(s) |
D12.776.467.984.050 D12.776.624.664.700.962 D23.529.984.050
|
Concept/Terms |
Wnt-5a Protein- Wnt-5a Protein
- Wnt 5a Protein
- Wingless-Type MMTV Integration Site Family, Member 5A
- Wingless Type MMTV Integration Site Family, Member 5A
- Wnt5a Protein
|
Below are MeSH descriptors whose meaning is more general than "Wnt-5a Protein".
Below are MeSH descriptors whose meaning is more specific than "Wnt-5a Protein".
This graph shows the total number of publications written about "Wnt-5a Protein" by people in this website by year, and whether "Wnt-5a Protein" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Wnt-5a Protein" by people in Profiles.
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Wnt5a induces catabolic signaling and matrix metalloproteinase production in human articular chondrocytes. Osteoarthritis Cartilage. 2017 09; 25(9):1505-1515.