"Apoptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
| Descriptor ID |
D017209
|
| MeSH Number(s) |
G04.146.160
|
| Concept/Terms |
Apoptosis- Apoptosis
- Programmed Cell Death, Type I
|
Below are MeSH descriptors whose meaning is more general than "Apoptosis".
Below are MeSH descriptors whose meaning is more specific than "Apoptosis".
This graph shows the total number of publications written about "Apoptosis" by people in this website by year, and whether "Apoptosis" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 2 | 5 |
| 1997 | 0 | 3 | 3 |
| 1998 | 1 | 1 | 2 |
| 1999 | 4 | 2 | 6 |
| 2000 | 0 | 2 | 2 |
| 2001 | 4 | 0 | 4 |
| 2002 | 2 | 3 | 5 |
| 2003 | 5 | 4 | 9 |
| 2004 | 5 | 7 | 12 |
| 2005 | 1 | 7 | 8 |
| 2006 | 1 | 2 | 3 |
| 2007 | 6 | 4 | 10 |
| 2008 | 3 | 2 | 5 |
| 2009 | 3 | 2 | 5 |
| 2010 | 0 | 3 | 3 |
| 2011 | 2 | 3 | 5 |
| 2012 | 2 | 3 | 5 |
| 2013 | 4 | 4 | 8 |
| 2014 | 2 | 5 | 7 |
| 2015 | 0 | 5 | 5 |
| 2016 | 0 | 3 | 3 |
| 2017 | 2 | 5 | 7 |
| 2018 | 1 | 5 | 6 |
| 2019 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 4 | 4 |
To return to the timeline,
click here.
Below are the most recent publications written about "Apoptosis" by people in Profiles.
-
Lymphatic cells do not functionally integrate into 3D organotypic brain slice cultures, but aggregate around penetrating blood vessels. Exp Brain Res. 2022 Sep; 240(9):2349-2358.
-
Wnt/?-Catenin Protects Lymphocytes from HIV-Mediated Apoptosis via Induction of Bcl-xL. Viruses. 2022 07 02; 14(7).
-
Canady Cold Helios Plasma Reduces Soft Tissue Sarcoma Viability by Inhibiting Proliferation, Disrupting Cell Cycle, and Inducing Apoptosis: A Preliminary Report. Molecules. 2022 Jun 29; 27(13).
-
Presence of CrkI-containing microvesicles in squamous cell carcinomas could have ramifications on tumor biology and cancer therapeutics. Sci Rep. 2022 03 21; 12(1):4803.
-
Xenogeneic fibroblasts inhibit the growth of the breast and ovarian cancer cell lines in co-culture. Neoplasma. 2021 Nov; 68(6):1265-1271.
-
RNS60, a physically-modified saline, inhibits glial activation, suppresses neuronal apoptosis and protects memory in a mouse model of traumatic brain injury. Exp Neurol. 2020 06; 328:113279.
-
Mechanical instability induces osteoclast differentiation independent of the presence of a fibrous tissue interface and osteocyte apoptosis in a rat model for aseptic loosening. Acta Orthop. 2020 02; 91(1):115-120.
-
The histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells. J Biol Chem. 2019 06 07; 294(23):9186-9197.
-
A critical role of epigenetic inactivation of miR-9 in EVI1high pediatric AML. Mol Cancer. 2019 02 27; 18(1):30.
-
Alpha ketoglutarate levels, regulated by p53 and OGDH, determine autophagy and cell fate/apoptosis in response to Nutlin-3a. Cancer Biol Ther. 2019; 20(3):252-260.