"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.
| Descriptor ID |
D012333
|
| MeSH Number(s) |
D13.444.735.544
|
| Concept/Terms |
mRNA, Polyadenylated- mRNA, Polyadenylated
- RNA, Messenger, Polyadenylated
- Messenger RNA, Polyadenylated
- Polyadenylated Messenger RNA
- RNA, Polyadenylated Messenger
- Polyadenylated mRNA
- Poly(A)+ mRNA
|
Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".
Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".
This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 |
| 1997 | 0 | 6 | 6 |
| 1998 | 1 | 7 | 8 |
| 1999 | 0 | 3 | 3 |
| 2000 | 0 | 3 | 3 |
| 2001 | 1 | 6 | 7 |
| 2002 | 1 | 6 | 7 |
| 2003 | 0 | 8 | 8 |
| 2004 | 1 | 2 | 3 |
| 2005 | 1 | 9 | 10 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 4 | 5 |
| 2008 | 0 | 7 | 7 |
| 2009 | 0 | 7 | 7 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 5 | 5 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 3 | 4 |
| 2016 | 0 | 2 | 2 |
| 2017 | 4 | 4 | 8 |
| 2018 | 0 | 4 | 4 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "RNA, Messenger" by people in Profiles.
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Notch signaling is activated in knee-innervating dorsal root ganglia in experimental models of osteoarthritis joint pain. Arthritis Res Ther. 2023 04 15; 25(1):63.
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COVID-19 symptom relationship to antibody response and ACE2 neutralization in recovered health systems employees before and after mRNA BNT162b2 COVID-19 vaccine. PLoS One. 2022; 17(9):e0273323.
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m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection. Front Immunol. 2021; 12:705232.
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Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis. Cell Rep. 2021 04 13; 35(2):108991.
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Dietary Egg Protein Prevents Hyperhomocysteinemia via Upregulation of Hepatic Betaine-Homocysteine S-Methyltransferase Activity in Folate-Restricted Rats. J Nutr. 2019 08 01; 149(8):1369-1376.
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Aging and HIV-1 alter the function of specific K+ channels in prefrontal cortex pyramidal neurons. Neurosci Lett. 2019 08 24; 708:134341.
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The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Sci Transl Med. 2018 12 19; 10(472).
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Anti-a4?7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals. Sci Transl Med. 2018 10 03; 10(461).
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Loss of Intestinal Alkaline Phosphatase Leads to Distinct Chronic Changes in Bone Phenotype. J Surg Res. 2018 12; 232:325-331.
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Creatinine downregulates TNF-a in macrophage and T cell lines. Cytokine. 2018 Oct; 110:29-38.