"Ligands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme. Ligands are also molecules that donate or accept a pair of electrons to form a coordinate covalent bond with the central metal atom of a coordination complex. (From Dorland, 27th ed)
| Descriptor ID |
D008024
|
| MeSH Number(s) |
D27.720.470.480
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Ligands".
Below are MeSH descriptors whose meaning is more specific than "Ligands".
This graph shows the total number of publications written about "Ligands" by people in this website by year, and whether "Ligands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 3 | 3 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 2 | 2 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 5 | 5 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Ligands" by people in Profiles.
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Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier. Nat Commun. 2023 09 05; 14(1):5431.
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Ligand sensitivity of type-1 inositol 1,4,5-trisphosphate receptor is enhanced by the D2594K mutation. Pflugers Arch. 2023 05; 475(5):569-581.
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An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity. Cell. 2022 02 17; 185(4):614-629.e21.
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Circulating Tumor Cells and Biomarker Modulation with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin: Phase Ib Study in Patients with Soft-Tissue Sarcoma. Mol Cancer Ther. 2021 01; 20(1):132-141.
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Identification and characterization of PPARa ligands in the hippocampus. Nat Chem Biol. 2016 Dec; 12(12):1075-1083.
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Discovery of selective RIO2 kinase small molecule ligand. Biochim Biophys Acta. 2015 Oct; 1854(10 Pt B):1630-6.
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Comparing global and local likelihood score thresholds in multiclass laplacian-modified Naive Bayes protein target prediction. Comb Chem High Throughput Screen. 2015; 18(3):323-30.
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Downmodulation of CCR7 by HIV-1 Vpu results in impaired migration and chemotactic signaling within CD4? T cells. Cell Rep. 2014 Jun 26; 7(6):2019-30.
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Candida albicans primes TLR cytokine responses through a Dectin-1/Raf-1-mediated pathway. J Immunol. 2013 Apr 15; 190(8):4129-35.
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Extracellular protein disulfide isomerase regulates ligand-binding activity of aM?2 integrin and neutrophil recruitment during vascular inflammation. Blood. 2013 May 09; 121(19):3789-800, S1-15.