"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
| Descriptor ID |
D020013
|
| MeSH Number(s) |
G02.111.820.800.100 G03.143.500.100 G04.835.800.100
|
| Concept/Terms |
Calcium Signaling- Calcium Signaling
- Calcium Signalings
- Signaling, Calcium
- Signalings, Calcium
Calcium Waves- Calcium Waves
- Calcium Wave
- Wave, Calcium
- Waves, Calcium
- Calcium Oscillations
- Calcium Oscillation
- Oscillation, Calcium
- Oscillations, Calcium
Calcium Spikes- Calcium Spikes
- Calcium Spike
- Spike, Calcium
- Spikes, Calcium
Calcium Puffs- Calcium Puffs
- Calcium Puff
- Puff, Calcium
- Puffs, Calcium
Calcium Sparks- Calcium Sparks
- Calcium Spark
- Spark, Calcium
- Sparks, Calcium
|
Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".
Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".
This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 1 | 2 | 3 |
| 2004 | 3 | 1 | 4 |
| 2005 | 4 | 0 | 4 |
| 2006 | 3 | 0 | 3 |
| 2007 | 3 | 1 | 4 |
| 2008 | 2 | 0 | 2 |
| 2009 | 4 | 0 | 4 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 1 | 2 |
| 2012 | 2 | 1 | 3 |
| 2013 | 3 | 2 | 5 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 3 | 2 | 5 |
| 2018 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
| 2022 | 2 | 0 | 2 |
| 2024 | 0 | 3 | 3 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calcium Signaling" by people in Profiles.
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Disrupting the feed-forward cycle of RyR1 Ca2+ leak and oxidative stress mitigates doxorubicin-induced skeletal myopathy. Am J Physiol Cell Physiol. 2026 07 01; 331(1):C59-C73.
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Inositol 1,4,5-Trisphosphate Receptor 1 Gain-of-Function Increases the Risk for Cardiac Arrhythmias in Mice and Humans. Circulation. 2025 Mar 25; 151(12):847-862.
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Blink nadir measurements of sarcoplasmic reticulum are consistent with strong local Ca2+ depletion. Biophys J. 2025 Jan 21; 124(2):245-255.
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Alda-1 attenuation of binge alcohol-caused atrial arrhythmias through a novel mechanism of suppressed c-Jun N-terminal Kinase-2 activity. J Mol Cell Cardiol. 2024 12; 197:11-19.
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Mechanism of carvedilol induced action potential and calcium alternans. Channels (Austin). 2022 12; 16(1):97-112.
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Quantification of the calcium signaling deficit in muscles devoid of triadin. PLoS One. 2022; 17(2):e0264146.
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Dantrolene hinders dengue virus-induced upregulation and translocation of calmodulin to cardiac cell nuclei. Virology. 2021 01 15; 553:81-93.
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Mitochondrial calcium uniporter complex activation protects against calcium alternans in atrial myocytes. Am J Physiol Heart Circ Physiol. 2020 10 01; 319(4):H873-H881.
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Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations. FEBS J. 2019 11; 286(22):4554-4578.
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Calcium-induced release of calcium in muscle: 50 years of work and the emerging consensus. J Gen Physiol. 2018 04 02; 150(4):521-537.