"Calsequestrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acidic protein found in SARCOPLASMIC RETICULUM that binds calcium to the extent of 700-900 nmoles/mg. It plays the role of sequestering calcium transported to the interior of the intracellular vesicle.
| Descriptor ID |
D002155
|
| MeSH Number(s) |
D12.776.157.125.155 D12.776.210.500.220
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Calsequestrin".
Below are MeSH descriptors whose meaning is more specific than "Calsequestrin".
This graph shows the total number of publications written about "Calsequestrin" by people in this website by year, and whether "Calsequestrin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 1 | 2 |
| 2009 | 3 | 1 | 4 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 3 | 1 | 4 |
| 2014 | 1 | 0 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Calsequestrin" by people in Profiles.
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Alterations of?housekeeping?proteins in human aged and diseased hearts. Pflugers Arch. 2021 03; 473(3):351-362.
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Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle. Proc Natl Acad Sci U S A. 2017 01 24; 114(4):E638-E647.
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Characterization of Post-Translational Modifications to Calsequestrins of Cardiac and Skeletal Muscle. Int J Mol Sci. 2016 Sep 13; 17(9).
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Characterization of Two Human Skeletal Calsequestrin Mutants Implicated in Malignant Hyperthermia and Vacuolar Aggregate Myopathy. J Biol Chem. 2015 Nov 27; 290(48):28665-74.
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The couplonopathies: A comparative approach to a class of diseases of skeletal and cardiac muscle. J Gen Physiol. 2015 Jun; 145(6):459-74.
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A better method to measure total calcium in biological samples yields immediate payoffs. J Gen Physiol. 2015 Mar; 145(3):167-71.
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The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice. Biochem J. 2014 Jul 01; 461(1):99-106.
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Potential role of cardiac calsequestrin in the lethal arrhythmic effects of cocaine. Drug Alcohol Depend. 2013 Dec 01; 133(2):344-51.
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Mechanism of calsequestrin regulation of single cardiac ryanodine receptor in normal and pathological conditions. J Gen Physiol. 2013 Aug; 142(2):127-36.
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Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia. J Physiol. 2013 Sep 15; 591(18):4439-57.