"Calsequestrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acidic protein found in SARCOPLASMIC RETICULUM that binds calcium to the extent of 700-900 nmoles/mg. It plays the role of sequestering calcium transported to the interior of the intracellular vesicle.
| Descriptor ID |
D002155
|
| MeSH Number(s) |
D12.776.157.125.155 D12.776.210.500.220
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Calsequestrin".
Below are MeSH descriptors whose meaning is more specific than "Calsequestrin".
This graph shows the total number of publications written about "Calsequestrin" by people in this website by year, and whether "Calsequestrin" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 1 | 2 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Calsequestrin" by people in Profiles.
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Calsequestrin depolymerizes when calcium is depleted in the sarcoplasmic reticulum of working muscle. Proc Natl Acad Sci U S A. 2017 01 24; 114(4):E638-E647.
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Characterization of Post-Translational Modifications to Calsequestrins of Cardiac and Skeletal Muscle. Int J Mol Sci. 2016 Sep 13; 17(9).
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Characterization of Two Human Skeletal Calsequestrin Mutants Implicated in Malignant Hyperthermia and Vacuolar Aggregate Myopathy. J Biol Chem. 2015 Nov 27; 290(48):28665-74.
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The couplonopathies: A comparative approach to a class of diseases of skeletal and cardiac muscle. J Gen Physiol. 2015 Jun; 145(6):459-74.
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A better method to measure total calcium in biological samples yields immediate payoffs. J Gen Physiol. 2015 Mar; 145(3):167-71.
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Altered Ca2+ concentration, permeability and buffering in the myofibre Ca2+ store of a mouse model of malignant hyperthermia. J Physiol. 2013 Sep 15; 591(18):4439-57.
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Dynamic measurement of the calcium buffering properties of the sarcoplasmic reticulum in mouse skeletal muscle. J Physiol. 2013 Jan 15; 591(2):423-42.
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Measurement of RyR permeability reveals a role of calsequestrin in termination of SR Ca(2+) release in skeletal muscle. J Gen Physiol. 2011 Aug; 138(2):231-47.
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D4cpv-calsequestrin: a sensitive ratiometric biosensor accurately targeted to the calcium store of skeletal muscle. J Gen Physiol. 2011 Aug; 138(2):211-29.
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Paradoxical buffering of calcium by calsequestrin demonstrated for the calcium store of skeletal muscle. J Gen Physiol. 2010 Sep; 136(3):325-38.