Ryanodine Receptor Calcium Release Channel
"Ryanodine Receptor Calcium Release Channel" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tetrameric calcium release channel in the SARCOPLASMIC RETICULUM membrane of SMOOTH MUSCLE CELLS, acting oppositely to SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES. It is important in skeletal and cardiac excitation-contraction coupling and studied by using RYANODINE. Abnormalities are implicated in CARDIAC ARRHYTHMIAS and MUSCULAR DISEASES.
| Descriptor ID |
D019837
|
| MeSH Number(s) |
D12.776.157.530.400.150.800 D12.776.210.500.800 D12.776.543.550.450.150.800 D12.776.543.585.400.150.800
|
| Concept/Terms |
Ryanodine Receptor Calcium Release Channel- Ryanodine Receptor Calcium Release Channel
- Receptor, Ryanodine
- Ca Release Channel-Ryanodine Receptor
- Ca Release Channel Ryanodine Receptor
- Calcium-Ryanodine Receptor Complex
- Calcium Ryanodine Receptor Complex
- Complex, Calcium-Ryanodine Receptor
- Receptor Complex, Calcium-Ryanodine
- Ryanodine Receptor
|
Below are MeSH descriptors whose meaning is more general than "Ryanodine Receptor Calcium Release Channel".
Below are MeSH descriptors whose meaning is more specific than "Ryanodine Receptor Calcium Release Channel".
This graph shows the total number of publications written about "Ryanodine Receptor Calcium Release Channel" by people in this website by year, and whether "Ryanodine Receptor Calcium Release Channel" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 2 | 2 |
| 1998 | 2 | 2 | 4 |
| 1999 | 3 | 0 | 3 |
| 2000 | 1 | 0 | 1 |
| 2002 | 4 | 1 | 5 |
| 2003 | 3 | 0 | 3 |
| 2004 | 6 | 0 | 6 |
| 2005 | 6 | 1 | 7 |
| 2006 | 1 | 1 | 2 |
| 2007 | 3 | 4 | 7 |
| 2008 | 4 | 2 | 6 |
| 2009 | 5 | 0 | 5 |
| 2010 | 2 | 1 | 3 |
| 2011 | 3 | 1 | 4 |
| 2012 | 3 | 1 | 4 |
| 2013 | 4 | 1 | 5 |
| 2014 | 3 | 2 | 5 |
| 2015 | 1 | 2 | 3 |
| 2016 | 2 | 2 | 4 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 1 | 3 |
| 2019 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 3 | 0 | 3 |
| 2022 | 1 | 0 | 1 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ryanodine Receptor Calcium Release Channel" by people in Profiles.
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Muscle calcium stress cleaves junctophilin1, unleashing a gene regulatory program predicted to correct glucose dysregulation. Elife. 2023 02 01; 12.
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Quantification of the calcium signaling deficit in muscles devoid of triadin. PLoS One. 2022; 17(2):e0264146.
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Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation. Circ Res. 2021 07 23; 129(3):e35-e52.
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Simulating cardiac Ca2+ release units: effects of RyR cluster size and Ca2+ buffers on diastolic Ca2+ leak. Pflugers Arch. 2021 03; 473(3):435-446.
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Cardiac ryanodine receptor calcium release deficiency syndrome. Sci Transl Med. 2021 02 03; 13(579).
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Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not ?-Amyloid Accumulation. Cell Rep. 2020 09 22; 32(12):108169.
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A multi-dimensional analysis of genotype-phenotype discordance in malignant hyperthermia susceptibility. Br J Anaesth. 2020 12; 125(6):995-1001.
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Recruiting RyRs to Open in a Ca2+ Release Unit: Single-RyR Gating Properties Make RyR Group Dynamics. Biophys J. 2020 01 07; 118(1):232-242.
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Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations. FEBS J. 2019 11; 286(22):4554-4578.
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Ryanodine Receptor Open Times Are Determined in the Closed State. Biophys J. 2018 10 02; 115(7):1160-1165.