Mutagenesis, Site-Directed
"Mutagenesis, Site-Directed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Genetically engineered MUTAGENESIS at a specific site in the DNA molecule that introduces a base substitution, or an insertion or deletion.
Descriptor ID |
D016297
|
MeSH Number(s) |
E05.393.420.601.575
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Concept/Terms |
Mutagenesis, Site-Directed- Mutagenesis, Site-Directed
- Mutagenesis, Site Directed
- Site-Specific Mutagenesis
- Site Specific Mutagenesis
- Mutagenesis, Site-Specific
- Mutageneses, Site-Specific
- Mutagenesis, Site Specific
- Site-Specific Mutageneses
- Site-Directed Mutagenesis
- Mutageneses, Site-Directed
- Site Directed Mutagenesis
- Site-Directed Mutageneses
Oligonucleotide-Directed Mutagenesis- Oligonucleotide-Directed Mutagenesis
- Oligonucleotide Directed Mutagenesis
- Mutagenesis, Oligonucleotide-Directed
- Mutageneses, Oligonucleotide-Directed
- Mutagenesis, Oligonucleotide Directed
- Oligonucleotide-Directed Mutageneses
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Below are MeSH descriptors whose meaning is more general than "Mutagenesis, Site-Directed".
Below are MeSH descriptors whose meaning is more specific than "Mutagenesis, Site-Directed".
This graph shows the total number of publications written about "Mutagenesis, Site-Directed" by people in this website by year, and whether "Mutagenesis, Site-Directed" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 2 | 2 |
2004 | 0 | 1 | 1 |
2006 | 0 | 2 | 2 |
2007 | 0 | 2 | 2 |
2008 | 0 | 1 | 1 |
2011 | 0 | 2 | 2 |
2014 | 0 | 1 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mutagenesis, Site-Directed" by people in Profiles.
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Selective targeting of the TLR2/MyD88/NF-?B pathway reduces a-synuclein spreading in vitro and in vivo. Nat Commun. 2021 09 10; 12(1):5382.
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O-GlcNAc modification of Sox2 regulates self-renewal in pancreatic cancer by promoting its stability. Theranostics. 2019; 9(12):3410-3424.
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The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias. Nat Med. 2014 Feb; 20(2):184-92.
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Mesenchymal stem cells expressing insulin-like growth factor-I (MSCIGF) promote fracture healing and restore new bone formation in Irs1 knockout mice: analyses of MSCIGF autocrine and paracrine regenerative effects. Stem Cells. 2011 Oct; 29(10):1537-48.
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Investigations of the catalytic mechanism of thioredoxin glutathione reductase from Schistosoma mansoni. Biochemistry. 2011 Jul 05; 50(26):5870-82.
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Cataracts are caused by alterations of a critical N-terminal positive charge in connexin50. Invest Ophthalmol Vis Sci. 2008 Jun; 49(6):2549-56.
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Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease. Hum Mol Genet. 2008 Apr 01; 17(7):929-35.
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A critical role for the E3-ligase activity of c-Cbl in VEGFR-2-mediated PLCgamma1 activation and angiogenesis. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5413-8.
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The beta-tail domain (betaTD) regulates physiologic ligand binding to integrin CD11b/CD18. Blood. 2007 Apr 15; 109(8):3513-20.
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Conductance and selectivity fluctuations in D127 mutants of the bacterial porin OmpF. Eur Biophys J. 2006 Dec; 36(1):13-22.