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Carl Maki

Concepts (347)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
40
2023
89
11.090
Why?
Imidazoles
15
2019
72
6.130
Why?
Piperazines
15
2019
90
6.020
Why?
Proto-Oncogene Proteins c-akt
8
2022
56
4.280
Why?
Proto-Oncogene Proteins c-mdm2
21
2019
29
3.190
Why?
Nuclear Proteins
15
2010
89
3.100
Why?
Antineoplastic Agents
8
2019
218
2.990
Why?
Drug Resistance, Neoplasm
9
2022
75
2.760
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
316
2.640
Why?
Cisplatin
7
2022
91
2.600
Why?
Cell Line, Tumor
22
2022
265
2.560
Why?
Apoptosis
12
2019
251
2.210
Why?
Receptors, Estrogen
3
2022
58
2.160
Why?
Autophagy
6
2021
30
2.030
Why?
Lung Neoplasms
4
2023
625
1.800
Why?
Neoplasms
6
2018
247
1.720
Why?
Breast Neoplasms
6
2022
329
1.640
Why?
Osteosarcoma
8
2018
29
1.600
Why?
Proto-Oncogene Proteins
10
2005
31
1.590
Why?
Tamoxifen
3
2022
30
1.520
Why?
Cyclin-Dependent Kinase Inhibitor p21
9
2013
22
1.520
Why?
Gene Expression Regulation, Neoplastic
4
2022
100
1.430
Why?
Insulin Receptor Substrate Proteins
2
2020
14
1.260
Why?
Tumor Suppressor Proteins
7
2010
33
1.250
Why?
Active Transport, Cell Nucleus
5
2007
12
1.130
Why?
Transcription Factors
4
2010
157
1.110
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
6
1.100
Why?
Humans
54
2023
29361
1.090
Why?
Bone Neoplasms
6
2018
102
1.070
Why?
Ubiquitin
4
2007
24
1.030
Why?
Cell Nucleus
8
2010
79
1.010
Why?
G1 Phase
6
2013
14
0.900
Why?
Cellular Senescence
3
2015
19
0.890
Why?
Mutation
7
2011
383
0.880
Why?
Glycolysis
3
2018
21
0.870
Why?
Retinoblastoma-Like Protein p130
1
2022
2
0.840
Why?
Transfection
12
2020
125
0.840
Why?
Colonic Neoplasms
3
2014
66
0.820
Why?
Fatty Acids
1
2021
38
0.810
Why?
Neoplasm Recurrence, Local
1
2022
184
0.810
Why?
Ubiquitins
6
2001
8
0.780
Why?
Animals
23
2022
4577
0.770
Why?
Triple Negative Breast Neoplasms
1
2020
15
0.760
Why?
DNA-Binding Proteins
6
2006
255
0.760
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
10
0.740
Why?
Receptors, Glucocorticoid
2
2012
8
0.730
Why?
Carboxypeptidases
2
2022
6
0.720
Why?
Receptor, IGF Type 1
2
2017
18
0.720
Why?
Proto-Oncogene Proteins c-bcl-2
2
2018
28
0.700
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
7
0.690
Why?
Phosphatidylinositol 3-Kinases
2
2021
48
0.690
Why?
Mice
13
2022
1620
0.680
Why?
Ketoglutaric Acids
1
2018
2
0.670
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.670
Why?
Sp1 Transcription Factor
1
2018
8
0.660
Why?
Adenosine
1
2018
13
0.650
Why?
Protein Conformation
3
2007
69
0.640
Why?
Protein Binding
9
2011
127
0.640
Why?
HSP90 Heat-Shock Proteins
2
2008
7
0.630
Why?
Tetraploidy
2
2014
2
0.630
Why?
G2 Phase
3
2013
4
0.630
Why?
Protein Kinase Inhibitors
2
2017
47
0.620
Why?
Receptors, Somatomedin
1
2017
4
0.620
Why?
Molecular Targeted Therapy
2
2014
32
0.600
Why?
Proteasome Endopeptidase Complex
5
2009
15
0.580
Why?
Loss of Heterozygosity
1
2016
4
0.570
Why?
DNA Mismatch Repair
1
2016
6
0.570
Why?
Transcription, Genetic
3
2006
108
0.550
Why?
Cell Lineage
1
2015
29
0.540
Why?
Signal Transduction
4
2021
483
0.540
Why?
RNA, Small Interfering
4
2019
64
0.540
Why?
Colorectal Neoplasms
1
2016
82
0.520
Why?
DNA Methylation
1
2016
124
0.520
Why?
Carcinogenesis
1
2014
21
0.510
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
28
0.500
Why?
Serine Endopeptidases
1
2014
17
0.500
Why?
Sirolimus
1
2014
15
0.490
Why?
Nitric Oxide
2
2014
101
0.490
Why?
Protein Kinases
1
2014
13
0.480
Why?
Models, Biological
1
2016
344
0.480
Why?
DNA Damage
7
2014
30
0.480
Why?
MCF-7 Cells
3
2021
17
0.470
Why?
Staurosporine
1
2013
1
0.460
Why?
Neoplasm Proteins
2
2003
50
0.460
Why?
Genes, p53
3
2011
17
0.450
Why?
Protein Kinase C-epsilon
1
2012
2
0.440
Why?
Apoptosis Regulatory Proteins
1
2012
16
0.430
Why?
Polyploidy
2
2010
2
0.430
Why?
Ultraviolet Rays
4
2001
9
0.430
Why?
Paclitaxel
2
2022
74
0.430
Why?
HCT116 Cells
4
2014
10
0.410
Why?
Gene Knockdown Techniques
3
2018
41
0.400
Why?
Cell Cycle
2
2010
41
0.380
Why?
Mitosis
2
2008
9
0.370
Why?
Zinc Fingers
2
2000
10
0.370
Why?
Intracellular Signaling Peptides and Proteins
1
2010
55
0.370
Why?
RNA Interference
3
2019
33
0.370
Why?
Phosphorylation
4
2016
159
0.370
Why?
Cytoskeleton
1
2010
51
0.370
Why?
Cell Line
7
2009
299
0.360
Why?
Cell Movement
1
2010
105
0.360
Why?
Puromycin
1
2009
1
0.350
Why?
Intranuclear Inclusion Bodies
1
2009
2
0.350
Why?
HSP70 Heat-Shock Proteins
1
2009
8
0.350
Why?
Methylation
2
2019
7
0.350
Why?
Cyclin-Dependent Kinases
3
2013
4
0.350
Why?
Immunoblotting
6
2007
55
0.350
Why?
Enzyme Activation
3
2014
109
0.350
Why?
DNA
7
2008
125
0.350
Why?
Histones
2
2019
28
0.340
Why?
Genetic Vectors
1
2009
60
0.340
Why?
DNA Replication
1
2008
12
0.340
Why?
Tumor Cells, Cultured
10
2003
145
0.340
Why?
Gene Expression Regulation
2
2010
284
0.340
Why?
Cell Cycle Checkpoints
2
2022
6
0.330
Why?
Reactive Oxygen Species
1
2009
126
0.330
Why?
Micronuclei, Chromosome-Defective
1
2008
1
0.330
Why?
Benzoquinones
1
2008
3
0.330
Why?
Lactams, Macrocyclic
1
2008
10
0.330
Why?
Cell Survival
4
2019
169
0.320
Why?
Antineoplastic Agents, Hormonal
2
2021
18
0.310
Why?
Nuclear Export Signals
1
2007
1
0.300
Why?
Checkpoint Kinase 1
2
2019
5
0.300
Why?
Oxygen
3
2015
85
0.290
Why?
Hodgkin Disease
1
2006
19
0.290
Why?
Base Sequence
7
2014
135
0.280
Why?
Heterocyclic Compounds, 3-Ring
2
2017
15
0.280
Why?
Protein Processing, Post-Translational
3
2014
35
0.280
Why?
CDC2-CDC28 Kinases
1
2005
1
0.270
Why?
Cell Cycle Proteins
1
2005
17
0.270
Why?
Gamma Rays
3
2012
16
0.270
Why?
Oxidative Stress
1
2005
124
0.260
Why?
RNA, Messenger
7
2012
323
0.260
Why?
Cytoplasm
4
2007
36
0.250
Why?
DNA Primers
4
2014
52
0.250
Why?
Promyelocytic Leukemia Protein
3
2010
3
0.240
Why?
Protein Structure, Tertiary
4
2006
61
0.240
Why?
Histone Deacetylase 1
1
2023
2
0.240
Why?
Retinoblastoma Protein
1
2023
10
0.240
Why?
Benzamides
1
2023
16
0.240
Why?
Clone Cells
2
2014
20
0.230
Why?
Mice, Knockout
6
2007
304
0.230
Why?
Histone Demethylases
1
2022
2
0.230
Why?
Lysine
1
2022
13
0.230
Why?
Cadherins
1
2022
31
0.220
Why?
Estrogen Receptor alpha
1
2022
15
0.220
Why?
CD27 Ligand
1
2022
2
0.220
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.220
Why?
Nanoparticles
1
2022
10
0.220
Why?
Trastuzumab
1
2022
25
0.220
Why?
Antigens, CD
1
2022
99
0.220
Why?
Antineoplastic Agents, Immunological
1
2022
18
0.220
Why?
Aurora Kinase A
1
2022
2
0.210
Why?
Aurora Kinase B
1
2022
2
0.210
Why?
Ribosomal Proteins
3
1990
4
0.210
Why?
Oxidation-Reduction
1
2021
73
0.200
Why?
Down-Regulation
2
2001
112
0.200
Why?
CDC2 Protein Kinase
2
2013
2
0.200
Why?
Cyclin B
2
2013
2
0.200
Why?
Cysteine Endopeptidases
2
2003
9
0.200
Why?
Cyclin A
2
2013
3
0.200
Why?
Recombinant Fusion Proteins
3
2006
29
0.200
Why?
Alkylating Agents
1
2001
1
0.200
Why?
Multienzyme Complexes
2
2003
26
0.200
Why?
Cells, Cultured
6
2007
676
0.200
Why?
Mice, Nude
1
2020
34
0.190
Why?
Tumor Protein p73
3
2006
3
0.190
Why?
Cyclins
2
1997
6
0.190
Why?
Dexamethasone
2
2012
48
0.180
Why?
Autophagy-Related Proteins
1
2019
2
0.180
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
3
0.180
Why?
Plasmids
3
2005
44
0.170
Why?
A549 Cells
1
2018
9
0.170
Why?
Pentose Phosphate Pathway
1
2018
3
0.170
Why?
Caspase 3
2
2022
30
0.160
Why?
Pyrazines
1
2017
10
0.160
Why?
Drug Synergism
1
2017
63
0.150
Why?
Disease Models, Animal
1
2020
726
0.150
Why?
Embryo, Mammalian
2
2007
31
0.150
Why?
Female
5
2022
16211
0.150
Why?
Fibroblasts
2
2007
95
0.150
Why?
DNA Repair
2
2010
7
0.140
Why?
Receptor Cross-Talk
1
2016
7
0.140
Why?
Immunoprecipitation
2
2007
24
0.140
Why?
Biological Assay
1
2016
9
0.140
Why?
Flow Cytometry
2
2015
199
0.140
Why?
Macrolides
1
2015
6
0.140
Why?
Caspase 8
1
2015
11
0.140
Why?
Superoxides
1
2015
26
0.140
Why?
Chloroquine
1
2015
12
0.140
Why?
Microscopy, Electron, Transmission
1
2015
30
0.140
Why?
Microscopy, Electron
1
2015
70
0.140
Why?
Microscopy, Confocal
1
2015
116
0.130
Why?
Diploidy
1
2014
4
0.130
Why?
G1 Phase Cell Cycle Checkpoints
1
2014
3
0.130
Why?
Phagosomes
1
2014
3
0.130
Why?
Fluorescent Antibody Technique
3
2003
78
0.130
Why?
Microtubule-Associated Proteins
1
2014
21
0.130
Why?
Nitric Oxide Synthase Type III
1
2014
17
0.130
Why?
Interferon-gamma
4
2003
109
0.120
Why?
MAP Kinase Signaling System
1
2014
38
0.120
Why?
Nitric Oxide Synthase Type II
1
2014
64
0.120
Why?
Fatty Acids, Unsaturated
2
2005
7
0.120
Why?
Genes, Tumor Suppressor
2
2004
12
0.120
Why?
Leupeptins
2
2006
4
0.110
Why?
Cysteine Proteinase Inhibitors
2
2006
10
0.110
Why?
Caspase 7
1
2012
2
0.110
Why?
Cell Line, Transformed
1
2012
17
0.110
Why?
Proto-Oncogene Proteins c-myc
1
2012
21
0.110
Why?
Hydrocortisone
1
2012
43
0.110
Why?
Cycloheximide
2
2005
10
0.100
Why?
Protein Synthesis Inhibitors
2
2005
9
0.100
Why?
Anti-Inflammatory Agents
1
2012
100
0.100
Why?
Telomere
1
2010
6
0.100
Why?
Multiprotein Complexes
1
2010
5
0.100
Why?
Protein Transport
1
2010
38
0.100
Why?
Drosophila
1
1990
7
0.100
Why?
Exons
2
2006
34
0.100
Why?
TOR Serine-Threonine Kinases
1
2010
10
0.090
Why?
Stress Fibers
1
2010
1
0.090
Why?
Pseudopodia
1
2010
5
0.090
Why?
Dendritic Cells
2
2001
56
0.090
Why?
Focal Adhesions
1
2010
9
0.090
Why?
Actins
1
2010
45
0.090
Why?
Neoplasm Invasiveness
1
2010
68
0.090
Why?
SUMO-1 Protein
1
2009
1
0.090
Why?
Cell Proliferation
1
2010
202
0.090
Why?
Protein Folding
1
2009
18
0.090
Why?
Gene Expression
2
2003
226
0.090
Why?
Cyclin B1
1
2008
1
0.080
Why?
HT29 Cells
1
2008
6
0.080
Why?
Cell Division
1
2008
114
0.080
Why?
Time Factors
2
2005
1618
0.080
Why?
Binding Sites
2
2005
71
0.080
Why?
Molecular Conformation
1
2007
15
0.080
Why?
Proteasome Inhibitors
1
2006
3
0.070
Why?
Response Elements
1
2006
13
0.070
Why?
Luciferases
1
2006
24
0.070
Why?
Genes, Reporter
1
2006
30
0.070
Why?
Male
2
2020
15637
0.070
Why?
Sequence Deletion
1
2006
12
0.070
Why?
Glucocorticoids
1
2006
67
0.070
Why?
Radiation, Ionizing
1
2005
1
0.070
Why?
Nucleic Acid Synthesis Inhibitors
1
2005
7
0.070
Why?
Liver Neoplasms
1
2007
103
0.070
Why?
Etoposide
1
2005
48
0.070
Why?
Cyclin E
1
2005
1
0.070
Why?
Cyclin-Dependent Kinase 2
1
2005
1
0.070
Why?
Serine
1
2005
11
0.070
Why?
Densitometry
1
2005
10
0.070
Why?
Amino Acid Motifs
1
2005
16
0.070
Why?
HeLa Cells
1
2005
50
0.070
Why?
Antifungal Agents
1
2005
36
0.070
Why?
Polymerase Chain Reaction
2
2003
161
0.070
Why?
Cloning, Molecular
2
2003
32
0.060
Why?
Protein Isoforms
1
2004
53
0.060
Why?
Baculoviridae
1
2003
1
0.060
Why?
Spodoptera
1
2003
1
0.060
Why?
Immunosorbent Techniques
1
2003
4
0.060
Why?
Saccharomyces cerevisiae Proteins
1
2003
9
0.060
Why?
Glutathione Transferase
1
2003
6
0.060
Why?
Mutagenesis
1
2003
12
0.060
Why?
Structure-Activity Relationship
1
2003
44
0.060
Why?
Gene Deletion
1
2003
40
0.060
Why?
Cyclic AMP Response Element-Binding Protein
1
2003
27
0.060
Why?
Interleukin-12
2
2001
38
0.060
Why?
Peptide Fragments
1
2003
99
0.060
Why?
Caspase 9
1
2022
12
0.060
Why?
Ceramides
1
2022
14
0.060
Why?
Xenograft Model Antitumor Assays
1
2022
25
0.060
Why?
Receptor, ErbB-2
1
2022
41
0.050
Why?
Chickens
1
2002
21
0.050
Why?
Receptors, Interleukin-2
1
2001
10
0.050
Why?
Interleukin-15
1
2001
11
0.050
Why?
Precipitin Tests
1
2001
12
0.050
Why?
Stress, Physiological
1
2001
20
0.050
Why?
Microscopy, Fluorescence
1
2001
85
0.050
Why?
Epitopes
1
2001
81
0.050
Why?
Thymus Gland
1
2001
23
0.050
Why?
Phosphoproteins
1
2001
26
0.050
Why?
Methyl Methanesulfonate
1
2001
1
0.050
Why?
Phosphoserine
1
2001
5
0.050
Why?
Mitomycin
1
2001
12
0.050
Why?
Salmon
1
2000
1
0.050
Why?
T-Lymphocyte Subsets
1
2001
86
0.050
Why?
Macrophages
1
2001
128
0.050
Why?
Glycoproteins
1
2001
58
0.050
Why?
Restriction Mapping
2
1990
5
0.050
Why?
Ligases
1
1999
7
0.050
Why?
Oncogene Proteins, Viral
1
1999
7
0.050
Why?
Cell Culture Techniques
1
2000
44
0.050
Why?
Repressor Proteins
1
1999
29
0.050
Why?
CD8-Positive T-Lymphocytes
1
2001
170
0.040
Why?
CD8 Antigens
1
1999
18
0.040
Why?
Point Mutation
1
1999
30
0.040
Why?
Intestinal Mucosa
1
2001
220
0.040
Why?
S Phase
1
1998
10
0.040
Why?
Acetylcysteine
1
1996
11
0.040
Why?
Enzyme Inhibitors
1
1997
145
0.040
Why?
Molecular Sequence Data
3
1995
246
0.040
Why?
Introns
2
2001
15
0.030
Why?
Computer Simulation
1
2016
218
0.030
Why?
Sequence Homology, Nucleic Acid
2
1990
16
0.030
Why?
Amino Acid Sequence
2
1990
193
0.030
Why?
Aniline Compounds
1
1990
41
0.020
Why?
Mice, Inbred C57BL
2
2001
432
0.020
Why?
Killer Cells, Natural
2
2001
91
0.020
Why?
Multigene Family
1
1989
8
0.020
Why?
Drosophila melanogaster
1
1989
18
0.020
Why?
Biological Evolution
1
1989
23
0.020
Why?
Blotting, Western
2
1998
170
0.020
Why?
Receptors, Interleukin
1
2001
5
0.010
Why?
Receptors, Interleukin-15
1
2001
3
0.010
Why?
Interleukin-2 Receptor beta Subunit
1
2001
2
0.010
Why?
CD40 Antigens
1
2001
9
0.010
Why?
Histocompatibility Antigens Class II
1
2001
13
0.010
Why?
Interleukin-2
1
2001
66
0.010
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2001
1
0.010
Why?
Lymphocyte Culture Test, Mixed
1
2001
8
0.010
Why?
Interferon Regulatory Factor-1
1
2001
5
0.010
Why?
Transgenes
1
2001
13
0.010
Why?
Mice, Inbred C3H
1
2001
33
0.010
Why?
Gene Transfer Techniques
1
2001
35
0.010
Why?
DNA Probes
1
2001
7
0.010
Why?
Transcriptional Activation
1
2001
23
0.010
Why?
Mice, Inbred BALB C
1
2001
264
0.010
Why?
Up-Regulation
1
2001
174
0.010
Why?
Cell Differentiation
1
2001
146
0.010
Why?
In Vitro Techniques
1
2001
213
0.010
Why?
Cattle
1
2001
218
0.010
Why?
Mice, Transgenic
1
2001
250
0.010
Why?
Intercellular Signaling Peptides and Proteins
1
2001
59
0.010
Why?
Lymphocyte Activation
1
2001
209
0.010
Why?
Tumor Suppressor Protein p14ARF
1
1999
2
0.010
Why?
Cell Hypoxia
1
1999
11
0.010
Why?
Ubiquitin-Protein Ligases
1
1999
36
0.010
Why?
Transposases
1
1999
1
0.010
Why?
Listeria monocytogenes
1
1999
5
0.010
Why?
Proteins
1
1999
73
0.010
Why?
Spleen
1
1999
51
0.010
Why?
Mitotic Index
1
1998
4
0.010
Why?
Adenocarcinoma
1
1998
189
0.010
Why?
Carcinoma, Squamous Cell
1
1998
178
0.010
Why?
Autoradiography
1
1995
11
0.010
Why?
Radiation Tolerance
1
1995
7
0.010
Why?
Electrophoresis, Gel, Two-Dimensional
1
1990
9
0.010
Why?
Xenopus laevis
1
1990
10
0.010
Why?
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