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Carl Maki

Concepts (349)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
40
2023
86
9.790
Why?
Imidazoles
15
2019
62
5.410
Why?
Piperazines
15
2019
81
5.330
Why?
Proto-Oncogene Proteins c-akt
8
2022
58
3.740
Why?
Drug Resistance, Neoplasm
10
2024
67
3.250
Why?
Antineoplastic Agents
9
2024
198
2.850
Why?
Proto-Oncogene Proteins c-mdm2
21
2019
34
2.790
Why?
Nuclear Proteins
15
2010
73
2.760
Why?
Cell Line, Tumor
23
2024
246
2.470
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
236
2.440
Why?
Cisplatin
7
2022
60
2.300
Why?
Apoptosis
12
2019
198
2.010
Why?
Receptors, Estrogen
3
2022
62
1.890
Why?
Autophagy
5
2021
28
1.670
Why?
Lung Neoplasms
4
2023
542
1.660
Why?
Neoplasms
6
2018
221
1.540
Why?
Triple Negative Breast Neoplasms
2
2024
16
1.510
Why?
Gene Expression Regulation, Neoplastic
5
2024
113
1.450
Why?
Breast Neoplasms
6
2022
401
1.400
Why?
Proto-Oncogene Proteins
10
2005
33
1.390
Why?
Osteosarcoma
8
2018
36
1.390
Why?
Tamoxifen
3
2022
30
1.330
Why?
Cyclin-Dependent Kinase Inhibitor p21
9
2013
23
1.330
Why?
Humans
54
2024
23331
1.150
Why?
Insulin Receptor Substrate Proteins
2
2020
14
1.100
Why?
Tumor Suppressor Proteins
7
2010
26
1.100
Why?
Transcription Factors
4
2010
149
0.990
Why?
Active Transport, Cell Nucleus
5
2007
10
0.990
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
9
0.960
Why?
Bone Neoplasms
6
2018
118
0.920
Why?
Ubiquitin
4
2007
29
0.900
Why?
Cell Nucleus
8
2010
69
0.890
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.860
Why?
Mutation
7
2011
328
0.790
Why?
G1 Phase
6
2013
16
0.790
Why?
Cellular Senescence
3
2015
15
0.780
Why?
Glycolysis
3
2018
11
0.770
Why?
Animals
22
2022
3287
0.750
Why?
Retinoblastoma-Like Protein p130
1
2022
3
0.740
Why?
Transfection
12
2020
120
0.740
Why?
Colonic Neoplasms
3
2014
56
0.720
Why?
Fatty Acids
1
2021
31
0.710
Why?
Neoplasm Recurrence, Local
1
2022
203
0.710
Why?
Ubiquitins
6
2001
8
0.680
Why?
DNA-Binding Proteins
6
2006
230
0.680
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
9
0.650
Why?
Receptors, Glucocorticoid
2
2012
5
0.640
Why?
Mice
13
2022
1236
0.640
Why?
Carboxypeptidases
2
2022
8
0.630
Why?
Receptor, IGF Type 1
2
2017
21
0.630
Why?
Proto-Oncogene Proteins c-bcl-2
2
2018
18
0.610
Why?
Phosphatidylinositol 3-Kinases
2
2021
44
0.600
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
10
0.600
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.590
Why?
Ketoglutaric Acids
1
2018
3
0.590
Why?
Sp1 Transcription Factor
1
2018
5
0.580
Why?
Adenosine
1
2018
8
0.570
Why?
Protein Conformation
3
2007
66
0.560
Why?
Protein Binding
9
2011
115
0.560
Why?
HSP90 Heat-Shock Proteins
2
2008
5
0.550
Why?
Tetraploidy
2
2014
3
0.550
Why?
G2 Phase
3
2013
5
0.550
Why?
Receptors, Somatomedin
1
2017
5
0.540
Why?
Protein Kinase Inhibitors
2
2017
55
0.540
Why?
Molecular Targeted Therapy
2
2014
31
0.520
Why?
Proteasome Endopeptidase Complex
5
2009
21
0.510
Why?
Loss of Heterozygosity
1
2016
6
0.490
Why?
DNA Mismatch Repair
1
2016
10
0.490
Why?
Signal Transduction
4
2021
403
0.490
Why?
Transcription, Genetic
3
2006
98
0.490
Why?
Cell Lineage
1
2015
25
0.480
Why?
RNA, Small Interfering
4
2019
77
0.470
Why?
DNA Methylation
1
2016
128
0.450
Why?
Carcinogenesis
1
2014
20
0.440
Why?
Nitric Oxide
2
2014
73
0.440
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
26
0.440
Why?
Serine Endopeptidases
1
2014
14
0.440
Why?
Colorectal Neoplasms
1
2016
109
0.440
Why?
Sirolimus
1
2014
20
0.430
Why?
Models, Biological
1
2016
306
0.430
Why?
Protein Kinases
1
2014
11
0.420
Why?
DNA Damage
7
2014
27
0.420
Why?
MCF-7 Cells
3
2021
15
0.410
Why?
Staurosporine
1
2013
2
0.400
Why?
Neoplasm Proteins
2
2003
51
0.400
Why?
Genes, p53
3
2011
19
0.400
Why?
Protein Kinase C-epsilon
1
2012
2
0.380
Why?
Apoptosis Regulatory Proteins
1
2012
10
0.380
Why?
Paclitaxel
2
2022
49
0.380
Why?
Polyploidy
2
2010
2
0.380
Why?
Ultraviolet Rays
4
2001
8
0.380
Why?
HCT116 Cells
4
2014
11
0.360
Why?
Gene Knockdown Techniques
3
2018
41
0.350
Why?
Cell Cycle
2
2010
33
0.330
Why?
Intracellular Signaling Peptides and Proteins
1
2010
46
0.330
Why?
Phosphorylation
4
2016
132
0.320
Why?
Mitosis
2
2008
7
0.320
Why?
Zinc Fingers
2
2000
10
0.320
Why?
Cytoskeleton
1
2010
33
0.320
Why?
RNA Interference
3
2019
36
0.320
Why?
Cell Line
7
2009
254
0.320
Why?
Cell Movement
1
2010
78
0.320
Why?
Puromycin
1
2009
1
0.310
Why?
Intranuclear Inclusion Bodies
1
2009
2
0.310
Why?
HSP70 Heat-Shock Proteins
1
2009
5
0.310
Why?
Methylation
2
2019
10
0.310
Why?
Cyclin-Dependent Kinases
3
2013
5
0.310
Why?
Gene Expression Regulation
2
2010
233
0.300
Why?
Immunoblotting
6
2007
54
0.300
Why?
Enzyme Activation
3
2014
110
0.300
Why?
DNA
7
2008
97
0.300
Why?
Histones
2
2019
28
0.300
Why?
Genetic Vectors
1
2009
55
0.300
Why?
Tumor Cells, Cultured
10
2003
126
0.300
Why?
DNA Replication
1
2008
10
0.300
Why?
Reactive Oxygen Species
1
2009
106
0.290
Why?
Cell Cycle Checkpoints
2
2022
7
0.290
Why?
Micronuclei, Chromosome-Defective
1
2008
1
0.290
Why?
Benzoquinones
1
2008
3
0.290
Why?
Lactams, Macrocyclic
1
2008
6
0.290
Why?
Cell Survival
4
2019
102
0.290
Why?
Antineoplastic Agents, Hormonal
2
2021
19
0.270
Why?
Nuclear Export Signals
1
2007
1
0.270
Why?
Oxygen
3
2015
58
0.260
Why?
Checkpoint Kinase 1
2
2019
7
0.260
Why?
Hodgkin Disease
1
2006
19
0.250
Why?
Base Sequence
7
2014
101
0.250
Why?
Heterocyclic Compounds, 3-Ring
2
2017
13
0.240
Why?
Protein Processing, Post-Translational
3
2014
33
0.240
Why?
CDC2-CDC28 Kinases
1
2005
1
0.240
Why?
Gamma Rays
3
2012
12
0.230
Why?
Cell Cycle Proteins
1
2005
16
0.230
Why?
Oxidative Stress
1
2005
81
0.230
Why?
RNA, Messenger
7
2012
285
0.230
Why?
Female
6
2024
13124
0.220
Why?
Cytoplasm
4
2007
33
0.220
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.220
Why?
DNA Primers
4
2014
50
0.220
Why?
Promyelocytic Leukemia Protein
3
2010
3
0.210
Why?
Interleukin-6
1
2024
73
0.210
Why?
Protein Structure, Tertiary
4
2006
60
0.210
Why?
Histone Deacetylase 1
1
2023
3
0.210
Why?
Retinoblastoma Protein
1
2023
11
0.210
Why?
Benzamides
1
2023
13
0.210
Why?
Clone Cells
2
2014
11
0.200
Why?
Mice, Knockout
6
2007
279
0.200
Why?
Histone Demethylases
1
2022
3
0.200
Why?
Lysine
1
2022
14
0.200
Why?
Cadherins
1
2022
30
0.200
Why?
Estrogen Receptor alpha
1
2022
15
0.200
Why?
Antigens, CD
1
2022
50
0.190
Why?
CD27 Ligand
1
2022
2
0.190
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.190
Why?
Nanoparticles
1
2022
11
0.190
Why?
Trastuzumab
1
2022
26
0.190
Why?
Biomarkers, Tumor
1
2024
200
0.190
Why?
Antineoplastic Agents, Immunological
1
2022
15
0.190
Why?
Aurora Kinase B
1
2022
3
0.190
Why?
Aurora Kinase A
1
2022
4
0.190
Why?
Ribosomal Proteins
3
1990
3
0.180
Why?
Oxidation-Reduction
1
2021
64
0.180
Why?
Cells, Cultured
6
2007
481
0.180
Why?
Down-Regulation
2
2001
90
0.180
Why?
CDC2 Protein Kinase
2
2013
3
0.180
Why?
Cysteine Endopeptidases
2
2003
11
0.180
Why?
Cyclin B
2
2013
4
0.180
Why?
Recombinant Fusion Proteins
3
2006
29
0.180
Why?
Cyclin A
2
2013
4
0.170
Why?
Alkylating Agents
1
2001
1
0.170
Why?
Multienzyme Complexes
2
2003
30
0.170
Why?
Mice, Nude
1
2020
25
0.170
Why?
Tumor Protein p73
3
2006
3
0.170
Why?
Cyclins
2
1997
5
0.160
Why?
Dexamethasone
2
2012
34
0.160
Why?
Autophagy-Related Proteins
1
2019
4
0.150
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.150
Why?
Plasmids
3
2005
43
0.150
Why?
A549 Cells
1
2018
11
0.150
Why?
Pentose Phosphate Pathway
1
2018
3
0.150
Why?
Caspase 3
2
2022
17
0.140
Why?
Disease Models, Animal
1
2020
517
0.140
Why?
Drug Synergism
1
2017
38
0.140
Why?
Pyrazines
1
2017
12
0.140
Why?
Embryo, Mammalian
2
2007
24
0.130
Why?
Fibroblasts
2
2007
54
0.130
Why?
DNA Repair
2
2010
7
0.130
Why?
Receptor Cross-Talk
1
2016
7
0.130
Why?
Immunoprecipitation
2
2007
19
0.120
Why?
Flow Cytometry
2
2015
104
0.120
Why?
Macrolides
1
2015
6
0.120
Why?
Caspase 8
1
2015
10
0.120
Why?
Superoxides
1
2015
23
0.120
Why?
Chloroquine
1
2015
7
0.120
Why?
Microscopy, Electron, Transmission
1
2015
24
0.120
Why?
Microscopy, Electron
1
2015
61
0.120
Why?
Microscopy, Confocal
1
2015
81
0.120
Why?
Diploidy
1
2014
2
0.110
Why?
G1 Phase Cell Cycle Checkpoints
1
2014
2
0.110
Why?
Fluorescent Antibody Technique
3
2003
53
0.110
Why?
Phagosomes
1
2014
2
0.110
Why?
Microtubule-Associated Proteins
1
2014
15
0.110
Why?
Nitric Oxide Synthase Type III
1
2014
11
0.110
Why?
Interferon-gamma
4
2003
74
0.110
Why?
MAP Kinase Signaling System
1
2014
36
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
64
0.110
Why?
Fatty Acids, Unsaturated
2
2005
11
0.100
Why?
Genes, Tumor Suppressor
2
2004
9
0.100
Why?
Leupeptins
2
2006
3
0.100
Why?
Cysteine Proteinase Inhibitors
2
2006
6
0.100
Why?
Caspase 7
1
2012
1
0.100
Why?
Cell Line, Transformed
1
2012
13
0.100
Why?
Proto-Oncogene Proteins c-myc
1
2012
14
0.100
Why?
Hydrocortisone
1
2012
38
0.090
Why?
Protein Synthesis Inhibitors
2
2005
6
0.090
Why?
Cycloheximide
2
2005
7
0.090
Why?
Anti-Inflammatory Agents
1
2012
72
0.090
Why?
Telomere
1
2010
6
0.090
Why?
Multiprotein Complexes
1
2010
3
0.090
Why?
Protein Transport
1
2010
29
0.090
Why?
Drosophila
1
1990
5
0.080
Why?
Dendritic Cells
2
2001
34
0.080
Why?
Exons
2
2006
30
0.080
Why?
TOR Serine-Threonine Kinases
1
2010
13
0.080
Why?
Stress Fibers
1
2010
1
0.080
Why?
Pseudopodia
1
2010
5
0.080
Why?
Focal Adhesions
1
2010
4
0.080
Why?
Actins
1
2010
35
0.080
Why?
Neoplasm Invasiveness
1
2010
89
0.080
Why?
Cell Proliferation
1
2010
168
0.080
Why?
Gene Expression
2
2003
178
0.080
Why?
SUMO-1 Protein
1
2009
1
0.080
Why?
Time Factors
2
2005
1289
0.080
Why?
Protein Folding
1
2009
16
0.080
Why?
Cyclin B1
1
2008
1
0.070
Why?
Male
2
2020
12629
0.070
Why?
HT29 Cells
1
2008
8
0.070
Why?
Cell Division
1
2008
81
0.070
Why?
Binding Sites
2
2005
69
0.070
Why?
Molecular Conformation
1
2007
10
0.070
Why?
Proteasome Inhibitors
1
2006
2
0.070
Why?
Response Elements
1
2006
13
0.060
Why?
Luciferases
1
2006
25
0.060
Why?
Genes, Reporter
1
2006
22
0.060
Why?
Sequence Deletion
1
2006
16
0.060
Why?
Glucocorticoids
1
2006
60
0.060
Why?
Radiation, Ionizing
1
2005
2
0.060
Why?
Nucleic Acid Synthesis Inhibitors
1
2005
5
0.060
Why?
Liver Neoplasms
1
2007
103
0.060
Why?
Etoposide
1
2005
27
0.060
Why?
Cyclin E
1
2005
1
0.060
Why?
Cyclin-Dependent Kinase 2
1
2005
1
0.060
Why?
Serine
1
2005
9
0.060
Why?
Densitometry
1
2005
8
0.060
Why?
Amino Acid Motifs
1
2005
20
0.060
Why?
HeLa Cells
1
2005
36
0.060
Why?
Antifungal Agents
1
2005
38
0.060
Why?
Polymerase Chain Reaction
2
2003
115
0.060
Why?
Cloning, Molecular
2
2003
26
0.060
Why?
Protein Isoforms
1
2004
38
0.050
Why?
Baculoviridae
1
2003
1
0.050
Why?
Spodoptera
1
2003
1
0.050
Why?
Immunosorbent Techniques
1
2003
3
0.050
Why?
Glutathione Transferase
1
2003
4
0.050
Why?
Mutagenesis
1
2003
11
0.050
Why?
Saccharomyces cerevisiae Proteins
1
2003
12
0.050
Why?
Structure-Activity Relationship
1
2003
34
0.050
Why?
Gene Deletion
1
2003
40
0.050
Why?
Cyclic AMP Response Element-Binding Protein
1
2003
28
0.050
Why?
Peptide Fragments
1
2003
58
0.050
Why?
Interleukin-12
2
2001
34
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Xenograft Model Antitumor Assays
1
2022
21
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Receptor, ErbB-2
1
2022
52
0.050
Why?
Chickens
1
2002
32
0.050
Why?
Receptors, Interleukin-2
1
2001
7
0.050
Why?
Interleukin-15
1
2001
8
0.050
Why?
Precipitin Tests
1
2001
10
0.050
Why?
Stress, Physiological
1
2001
15
0.050
Why?
Epitopes
1
2001
39
0.050
Why?
Microscopy, Fluorescence
1
2001
69
0.040
Why?
Thymus Gland
1
2001
11
0.040
Why?
Phosphoproteins
1
2001
23
0.040
Why?
Methyl Methanesulfonate
1
2001
1
0.040
Why?
Phosphoserine
1
2001
4
0.040
Why?
T-Lymphocyte Subsets
1
2001
37
0.040
Why?
Macrophages
1
2001
98
0.040
Why?
Mitomycin
1
2001
10
0.040
Why?
Salmon
1
2000
1
0.040
Why?
Glycoproteins
1
2001
42
0.040
Why?
Restriction Mapping
2
1990
3
0.040
Why?
CD8-Positive T-Lymphocytes
1
2001
109
0.040
Why?
Cell Culture Techniques
1
2000
30
0.040
Why?
Ligases
1
1999
7
0.040
Why?
Oncogene Proteins, Viral
1
1999
5
0.040
Why?
Intestinal Mucosa
1
2001
155
0.040
Why?
Repressor Proteins
1
1999
33
0.040
Why?
CD8 Antigens
1
1999
11
0.040
Why?
Point Mutation
1
1999
25
0.040
Why?
S Phase
1
1998
11
0.040
Why?
Enzyme Inhibitors
1
1997
116
0.030
Why?
Acetylcysteine
1
1996
14
0.030
Why?
Molecular Sequence Data
3
1995
188
0.030
Why?
Introns
2
2001
14
0.030
Why?
Sequence Homology, Nucleic Acid
2
1990
7
0.020
Why?
Amino Acid Sequence
2
1990
149
0.020
Why?
Aniline Compounds
1
1990
29
0.020
Why?
Killer Cells, Natural
2
2001
41
0.020
Why?
Mice, Inbred C57BL
2
2001
360
0.020
Why?
Multigene Family
1
1989
7
0.020
Why?
Drosophila melanogaster
1
1989
9
0.020
Why?
Biological Evolution
1
1989
9
0.020
Why?
Blotting, Western
2
1998
132
0.020
Why?
Interleukin-2 Receptor beta Subunit
1
2001
1
0.010
Why?
Receptors, Interleukin-15
1
2001
2
0.010
Why?
Receptors, Interleukin
1
2001
3
0.010
Why?
CD40 Antigens
1
2001
6
0.010
Why?
Histocompatibility Antigens Class II
1
2001
6
0.010
Why?
Interleukin-2
1
2001
22
0.010
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2001
1
0.010
Why?
Interferon Regulatory Factor-1
1
2001
2
0.010
Why?
Lymphocyte Culture Test, Mixed
1
2001
4
0.010
Why?
Transgenes
1
2001
10
0.010
Why?
Mice, Inbred C3H
1
2001
19
0.010
Why?
Gene Transfer Techniques
1
2001
29
0.010
Why?
Mice, Inbred BALB C
1
2001
96
0.010
Why?
DNA Probes
1
2001
7
0.010
Why?
Transcriptional Activation
1
2001
29
0.010
Why?
Up-Regulation
1
2001
145
0.010
Why?
Lymphocyte Activation
1
2001
82
0.010
Why?
Cattle
1
2001
114
0.010
Why?
In Vitro Techniques
1
2001
155
0.010
Why?
Cell Differentiation
1
2001
125
0.010
Why?
Intercellular Signaling Peptides and Proteins
1
2001
46
0.010
Why?
Mice, Transgenic
1
2001
176
0.010
Why?
Tumor Suppressor Protein p14ARF
1
1999
1
0.010
Why?
Cell Hypoxia
1
1999
8
0.010
Why?
Ubiquitin-Protein Ligases
1
1999
26
0.010
Why?
Proteins
1
1999
54
0.010
Why?
Transposases
1
1999
1
0.010
Why?
Listeria monocytogenes
1
1999
3
0.010
Why?
Spleen
1
1999
29
0.010
Why?
Mitotic Index
1
1998
6
0.010
Why?
Adenocarcinoma
1
1998
135
0.010
Why?
Carcinoma, Squamous Cell
1
1998
164
0.010
Why?
Autoradiography
1
1995
5
0.010
Why?
Radiation Tolerance
1
1995
4
0.010
Why?
Xenopus laevis
1
1990
3
0.010
Why?
Electrophoresis, Gel, Two-Dimensional
1
1990
7
0.010
Why?
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