Carl Maki to Proto-Oncogene Proteins c-mdm2
This is a "connection" page, showing publications Carl Maki has written about Proto-Oncogene Proteins c-mdm2.
Connection Strength
3.049
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Modeling the Etiology of p53-mutated Cancer Cells. J Biol Chem. 2016 May 06; 291(19):10131-47.
Score: 0.532
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Acquisition of p53 mutations in response to the non-genotoxic p53 activator Nutlin-3. Oncogene. 2011 Nov 17; 30(46):4678-86.
Score: 0.381
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Pharmacologic activation of p53 by small-molecule MDM2 antagonists. Curr Pharm Des. 2011; 17(6):560-8.
Score: 0.370
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Regulation of p53 nuclear export through sequential changes in conformation and ubiquitination. J Biol Chem. 2007 May 11; 282(19):14616-25.
Score: 0.284
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MDM2 binding induces a conformational change in p53 that is opposed by heat-shock protein 90 and precedes p53 proteasomal degradation. J Biol Chem. 2007 May 11; 282(19):14626-34.
Score: 0.284
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The histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells. J Biol Chem. 2019 06 07; 294(23):9186-9197.
Score: 0.165
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p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a. J Mol Cell Biol. 2018 08 01; 10(4):331-340.
Score: 0.156
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p53-regulated autophagy is controlled by glycolysis and determines cell fate. Oncotarget. 2015 Sep 15; 6(27):23135-56.
Score: 0.128
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Novel roles for p53 in the genesis and targeting of tetraploid cancer cells. PLoS One. 2014; 9(11):e110844.
Score: 0.121
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p53 and p21(Waf1) are recruited to distinct PML-containing nuclear foci in irradiated and Nutlin-3a-treated U2OS cells. J Cell Biochem. 2010 Dec 01; 111(5):1280-90.
Score: 0.092
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P53 and p73 differ in their ability to inhibit glucocorticoid receptor (GR) transcriptional activity. Mol Cancer. 2006 Dec 06; 5:68.
Score: 0.070
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Control of p53 nuclear accumulation in stressed cells. FEBS Lett. 2005 Sep 12; 579(22):4978-84.
Score: 0.064
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MDM2 and promyelocytic leukemia antagonize each other through their direct interaction with p53. J Biol Chem. 2003 Dec 05; 278(49):49286-92.
Score: 0.056
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Physical and functional interactions between PML and MDM2. J Biol Chem. 2003 Aug 01; 278(31):29288-97.
Score: 0.055
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Stability and ubiquitination of the tumor suppressor protein p53. Methods Mol Biol. 2003; 223:27-38.
Score: 0.053
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MDM2 can promote the ubiquitination, nuclear export, and degradation of p53 in the absence of direct binding. J Biol Chem. 2001 Nov 30; 276(48):45255-60.
Score: 0.049
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Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents. FEBS Lett. 2001 Feb 16; 490(3):196-201.
Score: 0.047
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MDM2-dependent ubiquitination of nuclear and cytoplasmic P53. Oncogene. 2000 Nov 30; 19(51):5892-7.
Score: 0.046
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The MDM2 RING-finger domain is required to promote p53 nuclear export. Nat Cell Biol. 2000 Sep; 2(9):569-73.
Score: 0.045
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Oligomerization is required for p53 to be efficiently ubiquitinated by MDM2. J Biol Chem. 1999 Jun 04; 274(23):16531-5.
Score: 0.041
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Hypoxia induces p53 accumulation through MDM2 down-regulation and inhibition of E6-mediated degradation. Cancer Res. 1999 Dec 15; 59(24):6046-51.
Score: 0.011