"Mitomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antineoplastic antibiotic produced by Streptomyces caespitosus. It is one of the bi- or tri-functional ALKYLATING AGENTS causing cross-linking of DNA and inhibition of DNA synthesis.
| Descriptor ID |
D016685
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| MeSH Number(s) |
D02.806.400.249.350 D03.383.097.500.350 D03.633.100.473.412.249.350
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Mitomycin".
Below are MeSH descriptors whose meaning is more specific than "Mitomycin".
This graph shows the total number of publications written about "Mitomycin" by people in this website by year, and whether "Mitomycin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mitomycin" by people in Profiles.
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Downregulation of MDM2 stabilizes p53 by inhibiting p53 ubiquitination in response to specific alkylating agents. FEBS Lett. 2001 Feb 16; 490(3):196-201.
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Adjuvant therapy for pancreatic adenocarcinoma. J Gastrointest Surg. 2001 Jan-Feb; 5(1):6-7.
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Intensified adjuvant combined modality therapy for resected periampullary adenocarcinoma: acceptable toxicity and suggestion of improved 1-year disease-free survival. Int J Radiat Oncol Biol Phys. 2000 Nov 01; 48(4):1089-96.
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A phase III randomized prospective trial of external beam radiotherapy, mitomycin C, carmustine, and 6-mercaptopurine for the treatment of adults with anaplastic glioma of the brain. CNS Cancer Consortium. Int J Radiat Oncol Biol Phys. 1996 Mar 01; 34(4):793-802.
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A pilot study of the Functional Living Index-Cancer (FLIC) Scale for the assessment of quality of life for metastatic lung cancer patients. An Eastern Cooperative Oncology Group study. Am J Clin Oncol. 1988 Dec; 11(6):630-3.