Cyclin-Dependent Kinase Inhibitor p21
"Cyclin-Dependent Kinase Inhibitor p21" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.
| Descriptor ID |
D050759
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| MeSH Number(s) |
D12.644.360.225.500 D12.776.157.687.250 D12.776.167.187.500 D12.776.476.225.500 D12.776.624.776.355.500 D12.776.660.720.250
|
| Concept/Terms |
Cyclin-Dependent Kinase Inhibitor p21- Cyclin-Dependent Kinase Inhibitor p21
- Cyclin Dependent Kinase Inhibitor p21
- CDKN1 Protein
- Senescent Cell-Derived Inhibitor Protein 1
- Senescent Cell Derived Inhibitor Protein 1
- Cell Cycle Regulator p21
- Cyclin-Dependent Kinase Inhibitor 1A Protein
- Cyclin Dependent Kinase Inhibitor 1A Protein
- Cyclin Kinase Inhibitor p21
- p21 Cyclin Kinase Inhibitor
- CDKN1A Protein
- Cdk-Interacting Protein 1
- Cdk Interacting Protein 1
- Cdk2 Inhibitor Protein
- CDK2-Associated Protein 20 kDa
- CDK2 Associated Protein 20 kDa
- p21 Cell Cycle Regulator
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Below are MeSH descriptors whose meaning is more general than "Cyclin-Dependent Kinase Inhibitor p21".
Below are MeSH descriptors whose meaning is more specific than "Cyclin-Dependent Kinase Inhibitor p21".
This graph shows the total number of publications written about "Cyclin-Dependent Kinase Inhibitor p21" by people in this website by year, and whether "Cyclin-Dependent Kinase Inhibitor p21" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cyclin-Dependent Kinase Inhibitor p21" by people in Profiles.
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Sequential targeting of YAP1 and p21 enhances the elimination of senescent cells induced by the BET inhibitor JQ1. Cell Death Dis. 2021 Jan 25; 12(1):121.
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Geldanamycin promotes premature mitotic entry and micronucleation in irradiated p53/p21 deficient colon carcinoma cells. Oncogene. 2008 Sep 18; 27(42):5567-77.
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The molecular mechanisms of vitamin C on cell cycle regulation in B16F10 murine melanoma. J Cell Biochem. 2007 Nov 01; 102(4):1002-10.
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Abnormalities of molecular regulators of proliferation and apoptosis in carcinoma of the oral cavity and oropharynx. Auris Nasus Larynx. 2002 Apr; 29(2):165-74.
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Ubiquitination of p53 and p21 is differentially affected by ionizing and UV radiation. Mol Cell Biol. 1997 Jan; 17(1):355-63.
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In vivo ubiquitination and proteasome-mediated degradation of p53(1). Cancer Res. 1996 Jun 01; 56(11):2649-54.