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Lei Duan

Concepts (286)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
86
3.360
Why?
Drug Resistance, Neoplasm
9
2024
68
3.290
Why?
Proto-Oncogene Proteins c-akt
8
2022
60
2.550
Why?
Imidazoles
7
2019
62
2.480
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
236
2.470
Why?
Piperazines
7
2019
84
2.450
Why?
Receptors, Estrogen
6
2022
64
2.380
Why?
Autophagy
8
2022
31
2.200
Why?
Antineoplastic Agents
9
2024
198
2.160
Why?
Breast Neoplasms
9
2022
402
1.810
Why?
Cell Line, Tumor
19
2024
253
1.770
Why?
Tamoxifen
4
2022
30
1.690
Why?
Lung Neoplasms
4
2023
543
1.680
Why?
Cisplatin
5
2022
60
1.370
Why?
Apoptosis
9
2019
209
1.180
Why?
Triple Negative Breast Neoplasms
3
2024
17
1.160
Why?
Gene Expression Regulation, Neoplastic
3
2024
117
1.020
Why?
Carboxypeptidases
3
2022
8
0.990
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
9
0.970
Why?
Neoplasms
2
2018
230
0.970
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.880
Why?
Glycolysis
3
2018
13
0.780
Why?
Retinoblastoma-Like Protein p130
1
2022
3
0.750
Why?
Signal Transduction
8
2022
437
0.740
Why?
Fatty Acids
1
2021
38
0.720
Why?
Neoplasm Recurrence, Local
1
2022
206
0.720
Why?
Humans
37
2024
25973
0.700
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.680
Why?
Phosphatidylinositol 3-Kinases
2
2021
46
0.610
Why?
Insulin Receptor Substrate Proteins
2
2020
17
0.610
Why?
ErbB Receptors
3
2010
54
0.600
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.600
Why?
Ketoglutaric Acids
1
2018
3
0.600
Why?
Sp1 Transcription Factor
1
2018
5
0.590
Why?
Proto-Oncogene Proteins c-cbl
5
2010
12
0.590
Why?
Ubiquitin-Protein Ligases
4
2007
26
0.540
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
34
0.540
Why?
Cell Lineage
1
2015
25
0.480
Why?
Protein Kinase Inhibitors
2
2017
55
0.450
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
28
0.440
Why?
Serine Endopeptidases
1
2014
15
0.440
Why?
Sirolimus
1
2014
20
0.440
Why?
Mice
12
2022
1352
0.440
Why?
Nitric Oxide
1
2014
79
0.430
Why?
Protein Kinases
1
2014
13
0.430
Why?
Enzyme Activation
6
2014
118
0.430
Why?
Proto-Oncogene Proteins
2
2004
34
0.420
Why?
MCF-7 Cells
3
2021
15
0.420
Why?
cdc42 GTP-Binding Protein
2
2010
7
0.410
Why?
Animals
16
2022
3503
0.410
Why?
rac1 GTP-Binding Protein
2
2010
14
0.410
Why?
Mammary Glands, Human
2
2009
7
0.400
Why?
rhoA GTP-Binding Protein
2
2009
9
0.400
Why?
Receptors, Glycine
2
2009
2
0.390
Why?
Paclitaxel
2
2022
50
0.390
Why?
RNA, Small Interfering
3
2019
79
0.380
Why?
Epithelial Cells
2
2010
71
0.350
Why?
Cytotoxins
1
2010
1
0.350
Why?
Adherens Junctions
1
2010
3
0.350
Why?
Neoplasm Proteins
1
2010
55
0.340
Why?
Cell Movement
1
2010
79
0.330
Why?
Cell Proliferation
1
2010
173
0.330
Why?
Morphogenesis
1
2009
8
0.320
Why?
Methylation
2
2019
10
0.310
Why?
Osteosarcoma
3
2018
40
0.310
Why?
Caffeine
1
2009
54
0.310
Why?
Cell Survival
4
2019
116
0.310
Why?
Histones
2
2019
31
0.310
Why?
Ubiquitin
5
2007
32
0.300
Why?
Cell Cycle Checkpoints
2
2022
7
0.300
Why?
Kidney
1
2009
147
0.290
Why?
Bone Neoplasms
3
2018
128
0.280
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
11
0.280
Why?
Female
11
2024
14735
0.270
Why?
Antineoplastic Agents, Hormonal
2
2021
19
0.270
Why?
Checkpoint Kinase 1
2
2019
7
0.260
Why?
Phosphorylation
6
2016
143
0.260
Why?
RNA Interference
2
2019
37
0.260
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.260
Why?
Cell Line
6
2013
260
0.260
Why?
Mycobacterium tuberculosis
2
2005
17
0.260
Why?
Gene Knockdown Techniques
2
2018
43
0.260
Why?
Mitochondria
2
2005
60
0.250
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
10
0.230
Why?
Nitrogen
1
2004
4
0.230
Why?
Soil
1
2004
6
0.230
Why?
Oxygen
2
2015
63
0.230
Why?
Receptors, Antigen
1
2004
1
0.220
Why?
Biomarkers, Tumor
2
2024
203
0.220
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.220
Why?
Trastuzumab
2
2022
26
0.220
Why?
Interleukin-6
1
2024
74
0.220
Why?
Histone Deacetylase 1
1
2023
3
0.210
Why?
Retinoblastoma Protein
1
2023
11
0.210
Why?
Benzamides
1
2023
13
0.210
Why?
Lysosomes
1
2003
24
0.200
Why?
Histone Demethylases
1
2022
3
0.200
Why?
Lysine
1
2022
14
0.200
Why?
Mitochondrial Swelling
1
2002
1
0.200
Why?
Cadherins
1
2022
30
0.200
Why?
Estrogen Receptor alpha
1
2022
16
0.200
Why?
Antigens, CD
1
2022
50
0.200
Why?
CD27 Ligand
1
2022
2
0.200
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.200
Why?
Nanoparticles
1
2022
11
0.200
Why?
Antineoplastic Agents, Immunological
1
2022
15
0.190
Why?
Aurora Kinase B
1
2022
3
0.190
Why?
Aurora Kinase A
1
2022
4
0.190
Why?
Macrophages
1
2002
101
0.190
Why?
Glioblastoma
1
2022
13
0.190
Why?
Oxidation-Reduction
1
2021
64
0.180
Why?
Brain Neoplasms
1
2022
92
0.170
Why?
Receptor, ErbB-2
3
2022
52
0.170
Why?
Receptor, IGF Type 1
2
2017
21
0.160
Why?
Autophagy-Related Proteins
1
2019
4
0.160
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.160
Why?
A549 Cells
1
2018
11
0.150
Why?
Pentose Phosphate Pathway
1
2018
3
0.150
Why?
Mutation
4
2010
341
0.140
Why?
Adenosine
1
2018
8
0.140
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
19
0.140
Why?
Heterocyclic Compounds, 3-Ring
2
2017
14
0.140
Why?
Cell Transformation, Neoplastic
2
2009
32
0.140
Why?
Receptors, Somatomedin
1
2017
5
0.140
Why?
Epidermal Growth Factor
2
2010
26
0.140
Why?
Phospholipase C gamma
2
2007
8
0.140
Why?
Loss of Heterozygosity
1
2016
6
0.130
Why?
DNA Mismatch Repair
1
2016
10
0.130
Why?
Biological Assay
1
2016
7
0.120
Why?
Protein-Tyrosine Kinases
2
2007
17
0.120
Why?
Macrolides
1
2015
6
0.120
Why?
Caspase 8
1
2015
10
0.120
Why?
Superoxides
1
2015
24
0.120
Why?
Chloroquine
1
2015
7
0.120
Why?
Cellular Senescence
1
2015
17
0.120
Why?
Microscopy, Electron, Transmission
1
2015
26
0.120
Why?
Microscopy, Electron
1
2015
61
0.120
Why?
Microscopy, Confocal
1
2015
88
0.120
Why?
Flow Cytometry
1
2015
106
0.120
Why?
Phagosomes
1
2014
3
0.110
Why?
Microtubule-Associated Proteins
1
2014
19
0.110
Why?
Nitric Oxide Synthase Type III
1
2014
11
0.110
Why?
DNA Methylation
1
2016
157
0.110
Why?
Protein Processing, Post-Translational
1
2014
39
0.110
Why?
DNA Primers
1
2014
51
0.110
Why?
Colorectal Neoplasms
1
2016
110
0.110
Why?
MAP Kinase Signaling System
1
2014
37
0.110
Why?
Base Sequence
1
2014
105
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
67
0.110
Why?
Models, Biological
1
2016
318
0.110
Why?
DNA Damage
1
2014
28
0.110
Why?
Gene Expression Regulation
2
2007
266
0.110
Why?
Transfection
3
2020
122
0.110
Why?
Membrane Potentials
2
2005
167
0.100
Why?
Cell Adhesion
2
2010
31
0.100
Why?
Aniline Compounds
1
2013
35
0.100
Why?
Triazoles
1
2013
29
0.100
Why?
Dose-Response Relationship, Drug
2
2011
329
0.090
Why?
Triterpenes
1
2011
1
0.090
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
7
0.090
Why?
Ubiquitination
1
2010
15
0.090
Why?
Protein Transport
1
2010
31
0.090
Why?
Actins
1
2010
35
0.090
Why?
Cytoskeleton
1
2010
34
0.090
Why?
Amino Acid Sequence
1
2010
153
0.080
Why?
Molecular Sequence Data
1
2010
190
0.080
Why?
Cell Line, Transformed
1
2009
15
0.080
Why?
Mice, Nude
3
2020
25
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
242
0.080
Why?
Precancerous Conditions
1
2009
25
0.080
Why?
Urodela
1
2008
1
0.070
Why?
Retinal Ganglion Cells
1
2008
2
0.070
Why?
Glycine
1
2008
7
0.070
Why?
Neural Inhibition
1
2008
8
0.070
Why?
Synaptic Transmission
1
2008
24
0.070
Why?
RNA, Messenger
2
2013
306
0.070
Why?
Xenograft Model Antitumor Assays
2
2022
22
0.070
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
5
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
9
0.070
Why?
Neovascularization, Physiologic
1
2007
25
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.060
Why?
Necrosis
2
2005
26
0.060
Why?
Cells, Cultured
2
2008
512
0.060
Why?
Macrophages, Alveolar
1
2005
3
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
39
0.060
Why?
Immune Tolerance
1
2004
12
0.060
Why?
China
1
2004
48
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
16
0.060
Why?
Hydrogen-Ion Concentration
1
2004
131
0.060
Why?
Oncogene Proteins
1
2003
7
0.050
Why?
CHO Cells
1
2003
11
0.050
Why?
Cricetinae
1
2003
35
0.050
Why?
Mice, Knockout
1
2004
297
0.050
Why?
Embryo, Mammalian
1
2003
25
0.050
Why?
Endosomes
1
2003
8
0.050
Why?
Endocytosis
1
2003
17
0.050
Why?
Temperature
1
2003
61
0.050
Why?
Fibroblasts
1
2003
56
0.050
Why?
Blotting, Western
1
2003
145
0.050
Why?
Ionophores
1
2002
2
0.050
Why?
Calcimycin
1
2002
4
0.050
Why?
Ruthenium Red
1
2002
7
0.050
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Cytochrome c Group
1
2002
4
0.050
Why?
Blood Bactericidal Activity
1
2002
4
0.050
Why?
Down-Regulation
1
2003
99
0.050
Why?
Intracellular Membranes
1
2002
20
0.050
Why?
Caspases
1
2002
24
0.050
Why?
Calcium-Binding Proteins
1
2002
22
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Caspase 3
1
2022
20
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Permeability
1
2002
96
0.050
Why?
Gene Expression
1
2003
200
0.050
Why?
Molecular Docking Simulation
1
2022
2
0.050
Why?
Calcium Channels
1
2002
106
0.050
Why?
Genistein
1
2022
5
0.050
Why?
Protein Binding
3
2007
121
0.040
Why?
Structure-Activity Relationship
2
2013
37
0.040
Why?
Luciferases
2
2013
25
0.040
Why?
Disease Models, Animal
1
2020
577
0.030
Why?
Pyrazines
1
2017
12
0.030
Why?
Reproductive History
1
2017
1
0.030
Why?
Receptors, Progesterone
1
2017
26
0.030
Why?
Receptor Cross-Talk
1
2016
7
0.030
Why?
Population Surveillance
1
2017
112
0.030
Why?
Odds Ratio
1
2017
268
0.030
Why?
Tyrosine
2
2007
23
0.030
Why?
Protein Structure, Tertiary
2
2007
61
0.030
Why?
Case-Control Studies
1
2017
572
0.030
Why?
Computer Simulation
1
2016
193
0.030
Why?
Risk Assessment
1
2017
603
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
11
0.030
Why?
Biological Availability
1
2013
16
0.030
Why?
Genes, Reporter
1
2013
22
0.030
Why?
Administration, Oral
1
2013
104
0.030
Why?
Transcription, Genetic
1
2013
106
0.030
Why?
Rats, Sprague-Dawley
1
2013
320
0.020
Why?
Rats
1
2013
640
0.020
Why?
Male
2
2020
14280
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
5
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
6
0.020
Why?
Tumor Burden
1
2011
25
0.020
Why?
Drug Evaluation, Preclinical
1
2011
30
0.020
Why?
Quinazolines
1
2011
17
0.020
Why?
Mice, SCID
1
2011
42
0.020
Why?
Young Adult
1
2017
1942
0.020
Why?
Risk Factors
1
2017
2237
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
86
0.020
Why?
Antibodies, Monoclonal
1
2011
174
0.020
Why?
rho-Associated Kinases
1
2009
4
0.020
Why?
Telomerase
1
2009
10
0.020
Why?
Protein Kinase C
1
2009
48
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
63
0.020
Why?
Retina
1
2008
8
0.020
Why?
Ligands
1
2007
38
0.020
Why?
Laminin
1
2007
5
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Binding Sites
1
2007
71
0.020
Why?
Drug Combinations
1
2007
34
0.020
Why?
Mutagenesis, Site-Directed
1
2007
19
0.020
Why?
Gene Silencing
1
2007
23
0.020
Why?
Tumor Cells, Cultured
1
2007
129
0.020
Why?
Collagen
1
2007
85
0.020
Why?
Enzyme Inhibitors
1
2007
116
0.020
Why?
Proteoglycans
1
2007
131
0.020
Why?
Wound Healing
1
2007
157
0.020
Why?
Receptors, Purinergic P2
1
2005
1
0.010
Why?
Cytochromes c
1
2005
11
0.010
Why?
Adenosine Triphosphate
1
2005
22
0.010
Why?
Cyclosporine
1
2005
12
0.010
Why?
Adult
1
2017
7666
0.010
Why?
Molecular Conformation
1
2004
10
0.010
Why?
Middle Aged
1
2017
8775
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
10
0.010
Why?
Precipitin Tests
1
2003
11
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
26
0.010
Why?
Immunoblotting
1
2003
55
0.010
Why?
Plasmids
1
2003
42
0.010
Why?
Models, Genetic
1
2003
32
0.010
Why?
Mice, Transgenic
1
2003
214
0.010
Why?
Time Factors
1
2003
1391
0.010
Why?
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