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Lei Duan

Concepts (286)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
85
3.260
Why?
Drug Resistance, Neoplasm
9
2024
67
3.190
Why?
Proto-Oncogene Proteins c-akt
8
2022
56
2.470
Why?
Imidazoles
7
2019
62
2.400
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
236
2.400
Why?
Piperazines
7
2019
82
2.370
Why?
Receptors, Estrogen
6
2022
62
2.310
Why?
Autophagy
8
2022
30
2.120
Why?
Antineoplastic Agents
9
2024
194
2.110
Why?
Breast Neoplasms
9
2022
375
1.810
Why?
Cell Line, Tumor
19
2024
243
1.710
Why?
Tamoxifen
4
2022
29
1.640
Why?
Lung Neoplasms
4
2023
539
1.640
Why?
Cisplatin
5
2022
60
1.330
Why?
Apoptosis
9
2019
194
1.150
Why?
Triple Negative Breast Neoplasms
3
2024
15
1.120
Why?
Gene Expression Regulation, Neoplastic
3
2024
111
0.990
Why?
Carboxypeptidases
3
2022
8
0.960
Why?
Neoplasms
2
2018
218
0.950
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
9
0.940
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.850
Why?
Glycolysis
3
2018
12
0.750
Why?
Humans
37
2024
22912
0.730
Why?
Retinoblastoma-Like Protein p130
1
2022
3
0.730
Why?
Signal Transduction
8
2022
387
0.720
Why?
Neoplasm Recurrence, Local
1
2022
202
0.700
Why?
Fatty Acids
1
2021
33
0.700
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.660
Why?
Phosphatidylinositol 3-Kinases
2
2021
40
0.590
Why?
Insulin Receptor Substrate Proteins
2
2020
15
0.590
Why?
ErbB Receptors
3
2010
54
0.580
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.580
Why?
Ketoglutaric Acids
1
2018
3
0.580
Why?
Sp1 Transcription Factor
1
2018
5
0.570
Why?
Proto-Oncogene Proteins c-cbl
5
2010
11
0.570
Why?
Ubiquitin-Protein Ligases
4
2007
26
0.530
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
34
0.520
Why?
Cell Lineage
1
2015
25
0.470
Why?
Protein Kinase Inhibitors
2
2017
57
0.440
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
26
0.430
Why?
Mice
12
2022
1238
0.430
Why?
Serine Endopeptidases
1
2014
14
0.430
Why?
Sirolimus
1
2014
20
0.430
Why?
Nitric Oxide
1
2014
70
0.420
Why?
Protein Kinases
1
2014
12
0.420
Why?
Enzyme Activation
6
2014
109
0.410
Why?
Proto-Oncogene Proteins
2
2004
33
0.410
Why?
Animals
16
2022
3270
0.400
Why?
MCF-7 Cells
3
2021
15
0.400
Why?
cdc42 GTP-Binding Protein
2
2010
7
0.390
Why?
rac1 GTP-Binding Protein
2
2010
13
0.390
Why?
Mammary Glands, Human
2
2009
7
0.380
Why?
rhoA GTP-Binding Protein
2
2009
9
0.380
Why?
Receptors, Glycine
2
2009
2
0.380
Why?
Paclitaxel
2
2022
49
0.370
Why?
RNA, Small Interfering
3
2019
76
0.360
Why?
Epithelial Cells
2
2010
70
0.340
Why?
Cytotoxins
1
2010
1
0.340
Why?
Adherens Junctions
1
2010
3
0.330
Why?
Neoplasm Proteins
1
2010
52
0.330
Why?
Cell Movement
1
2010
77
0.320
Why?
Cell Proliferation
1
2010
163
0.320
Why?
Morphogenesis
1
2009
8
0.310
Why?
Methylation
2
2019
10
0.300
Why?
Osteosarcoma
3
2018
36
0.300
Why?
Histones
2
2019
28
0.300
Why?
Cell Survival
4
2019
99
0.300
Why?
Caffeine
1
2009
54
0.300
Why?
Ubiquitin
5
2007
29
0.290
Why?
Cell Cycle Checkpoints
2
2022
7
0.290
Why?
Kidney
1
2009
142
0.280
Why?
Female
11
2024
12939
0.280
Why?
Bone Neoplasms
3
2018
118
0.280
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
9
0.270
Why?
Antineoplastic Agents, Hormonal
2
2021
17
0.260
Why?
Checkpoint Kinase 1
2
2019
7
0.250
Why?
Phosphorylation
6
2016
130
0.250
Why?
RNA Interference
2
2019
36
0.250
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.250
Why?
Cell Line
6
2013
242
0.250
Why?
Mycobacterium tuberculosis
2
2005
17
0.250
Why?
Gene Knockdown Techniques
2
2018
40
0.250
Why?
Mitochondria
2
2005
55
0.240
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
10
0.230
Why?
Oxygen
2
2015
56
0.220
Why?
Nitrogen
1
2004
4
0.220
Why?
Soil
1
2004
6
0.220
Why?
Receptors, Antigen
1
2004
1
0.220
Why?
Biomarkers, Tumor
2
2024
200
0.220
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.210
Why?
Trastuzumab
2
2022
26
0.210
Why?
Interleukin-6
1
2024
70
0.210
Why?
Histone Deacetylase 1
1
2023
3
0.200
Why?
Retinoblastoma Protein
1
2023
11
0.200
Why?
Benzamides
1
2023
13
0.200
Why?
Lysosomes
1
2003
20
0.200
Why?
Histone Demethylases
1
2022
3
0.190
Why?
Lysine
1
2022
14
0.190
Why?
Mitochondrial Swelling
1
2002
1
0.190
Why?
Cadherins
1
2022
30
0.190
Why?
Estrogen Receptor alpha
1
2022
15
0.190
Why?
Antigens, CD
1
2022
49
0.190
Why?
CD27 Ligand
1
2022
2
0.190
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.190
Why?
Nanoparticles
1
2022
10
0.190
Why?
Antineoplastic Agents, Immunological
1
2022
15
0.190
Why?
Macrophages
1
2002
78
0.180
Why?
Aurora Kinase B
1
2022
3
0.180
Why?
Aurora Kinase A
1
2022
4
0.180
Why?
Glioblastoma
1
2022
9
0.180
Why?
Oxidation-Reduction
1
2021
56
0.180
Why?
Brain Neoplasms
1
2022
71
0.170
Why?
Receptor, ErbB-2
3
2022
52
0.160
Why?
Receptor, IGF Type 1
2
2017
21
0.150
Why?
Autophagy-Related Proteins
1
2019
4
0.150
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.150
Why?
A549 Cells
1
2018
10
0.150
Why?
Pentose Phosphate Pathway
1
2018
3
0.140
Why?
Mutation
4
2010
329
0.140
Why?
Adenosine
1
2018
8
0.140
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
18
0.140
Why?
Heterocyclic Compounds, 3-Ring
2
2017
13
0.140
Why?
Cell Transformation, Neoplastic
2
2009
30
0.140
Why?
Receptors, Somatomedin
1
2017
5
0.130
Why?
Phospholipase C gamma
2
2007
6
0.130
Why?
Epidermal Growth Factor
2
2010
26
0.130
Why?
Loss of Heterozygosity
1
2016
6
0.120
Why?
DNA Mismatch Repair
1
2016
10
0.120
Why?
Biological Assay
1
2016
7
0.120
Why?
Protein-Tyrosine Kinases
2
2007
13
0.120
Why?
Macrolides
1
2015
6
0.120
Why?
Caspase 8
1
2015
10
0.120
Why?
Superoxides
1
2015
23
0.120
Why?
Chloroquine
1
2015
7
0.120
Why?
Microscopy, Electron, Transmission
1
2015
22
0.120
Why?
Cellular Senescence
1
2015
15
0.120
Why?
Microscopy, Electron
1
2015
60
0.120
Why?
Flow Cytometry
1
2015
100
0.120
Why?
Microscopy, Confocal
1
2015
80
0.110
Why?
DNA Methylation
1
2016
129
0.110
Why?
Phagosomes
1
2014
2
0.110
Why?
Microtubule-Associated Proteins
1
2014
15
0.110
Why?
Nitric Oxide Synthase Type III
1
2014
10
0.110
Why?
Protein Processing, Post-Translational
1
2014
33
0.110
Why?
Colorectal Neoplasms
1
2016
106
0.110
Why?
DNA Primers
1
2014
49
0.110
Why?
MAP Kinase Signaling System
1
2014
33
0.110
Why?
Base Sequence
1
2014
99
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
62
0.110
Why?
Models, Biological
1
2016
302
0.110
Why?
Gene Expression Regulation
2
2007
226
0.100
Why?
DNA Damage
1
2014
25
0.100
Why?
Transfection
3
2020
115
0.100
Why?
Membrane Potentials
2
2005
168
0.100
Why?
Cell Adhesion
2
2010
30
0.100
Why?
Aniline Compounds
1
2013
29
0.100
Why?
Triazoles
1
2013
28
0.100
Why?
Dose-Response Relationship, Drug
2
2011
313
0.090
Why?
Triterpenes
1
2011
1
0.090
Why?
Estrogen Antagonists
1
2010
3
0.080
Why?
src-Family Kinases
3
2007
6
0.080
Why?
Ubiquitination
1
2010
14
0.080
Why?
Protein Transport
1
2010
29
0.080
Why?
Actins
1
2010
35
0.080
Why?
Cytoskeleton
1
2010
33
0.080
Why?
Amino Acid Sequence
1
2010
142
0.080
Why?
Molecular Sequence Data
1
2010
176
0.080
Why?
Cell Line, Transformed
1
2009
13
0.080
Why?
Mice, Nude
3
2020
25
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
240
0.080
Why?
Precancerous Conditions
1
2009
25
0.070
Why?
Urodela
1
2008
1
0.070
Why?
Retinal Ganglion Cells
1
2008
2
0.070
Why?
Glycine
1
2008
7
0.070
Why?
Synaptic Transmission
1
2008
20
0.070
Why?
Neural Inhibition
1
2008
8
0.070
Why?
RNA, Messenger
2
2013
283
0.070
Why?
Xenograft Model Antitumor Assays
2
2022
21
0.070
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
4
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
9
0.070
Why?
Neovascularization, Physiologic
1
2007
23
0.060
Why?
Oncogene Protein v-cbl
2
2003
2
0.060
Why?
Necrosis
2
2005
24
0.060
Why?
Cells, Cultured
2
2008
462
0.060
Why?
Macrophages, Alveolar
1
2005
3
0.060
Why?
Plant Development
1
2004
3
0.050
Why?
Drug Synergism
2
2017
38
0.050
Why?
Immune Tolerance
1
2004
11
0.050
Why?
China
1
2004
45
0.050
Why?
Receptors, Antigen, T-Cell
1
2004
16
0.050
Why?
Hydrogen-Ion Concentration
1
2004
125
0.050
Why?
Oncogene Proteins
1
2003
6
0.050
Why?
Mice, Knockout
1
2004
276
0.050
Why?
CHO Cells
1
2003
10
0.050
Why?
Cricetinae
1
2003
33
0.050
Why?
Embryo, Mammalian
1
2003
23
0.050
Why?
Endosomes
1
2003
8
0.050
Why?
Endocytosis
1
2003
16
0.050
Why?
Temperature
1
2003
56
0.050
Why?
Fibroblasts
1
2003
50
0.050
Why?
Blotting, Western
1
2003
132
0.050
Why?
Down-Regulation
1
2003
87
0.050
Why?
Ionophores
1
2002
2
0.050
Why?
Calcimycin
1
2002
4
0.050
Why?
Ruthenium Red
1
2002
7
0.050
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Cytochrome c Group
1
2002
4
0.050
Why?
Blood Bactericidal Activity
1
2002
4
0.050
Why?
Intracellular Membranes
1
2002
20
0.050
Why?
Caspases
1
2002
22
0.050
Why?
Calcium-Binding Proteins
1
2002
23
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Caspase 3
1
2022
17
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Permeability
1
2002
94
0.050
Why?
Gene Expression
1
2003
178
0.050
Why?
Calcium Channels
1
2002
107
0.050
Why?
Molecular Docking Simulation
1
2022
2
0.050
Why?
Genistein
1
2022
5
0.050
Why?
Protein Binding
3
2007
112
0.040
Why?
Structure-Activity Relationship
2
2013
30
0.040
Why?
Luciferases
2
2013
25
0.040
Why?
Disease Models, Animal
1
2020
526
0.030
Why?
Pyrazines
1
2017
11
0.030
Why?
Reproductive History
1
2017
1
0.030
Why?
Receptors, Progesterone
1
2017
26
0.030
Why?
Receptor Cross-Talk
1
2016
7
0.030
Why?
Odds Ratio
1
2017
219
0.030
Why?
Population Surveillance
1
2017
102
0.030
Why?
Case-Control Studies
1
2017
479
0.030
Why?
Tyrosine
2
2007
22
0.030
Why?
Protein Structure, Tertiary
2
2007
59
0.030
Why?
Computer Simulation
1
2016
173
0.030
Why?
Risk Assessment
1
2017
547
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
11
0.030
Why?
Biological Availability
1
2013
14
0.030
Why?
Genes, Reporter
1
2013
22
0.020
Why?
Administration, Oral
1
2013
96
0.020
Why?
Transcription, Genetic
1
2013
95
0.020
Why?
Rats, Sprague-Dawley
1
2013
314
0.020
Why?
Male
2
2020
12459
0.020
Why?
Young Adult
1
2017
1652
0.020
Why?
Rats
1
2013
623
0.020
Why?
Risk Factors
1
2017
1971
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
4
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
4
0.020
Why?
Tumor Burden
1
2011
23
0.020
Why?
Drug Evaluation, Preclinical
1
2011
22
0.020
Why?
Quinazolines
1
2011
17
0.020
Why?
Mice, SCID
1
2011
39
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
83
0.020
Why?
Antibodies, Monoclonal
1
2011
164
0.020
Why?
rho-Associated Kinases
1
2009
4
0.020
Why?
Telomerase
1
2009
8
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
45
0.020
Why?
Protein Kinase C
1
2009
47
0.020
Why?
Retina
1
2008
8
0.020
Why?
Ligands
1
2007
34
0.020
Why?
Binding Sites
1
2007
67
0.020
Why?
Laminin
1
2007
5
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Drug Combinations
1
2007
31
0.020
Why?
Mutagenesis, Site-Directed
1
2007
17
0.020
Why?
Gene Silencing
1
2007
23
0.020
Why?
Tumor Cells, Cultured
1
2007
125
0.020
Why?
Enzyme Inhibitors
1
2007
104
0.020
Why?
Collagen
1
2007
81
0.020
Why?
Proteoglycans
1
2007
120
0.020
Why?
Wound Healing
1
2007
107
0.020
Why?
Adult
1
2017
6924
0.010
Why?
Receptors, Purinergic P2
1
2005
1
0.010
Why?
Cytochromes c
1
2005
11
0.010
Why?
Adenosine Triphosphate
1
2005
21
0.010
Why?
Cyclosporine
1
2005
12
0.010
Why?
Middle Aged
1
2017
7911
0.010
Why?
Molecular Conformation
1
2004
9
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
8
0.010
Why?
Precipitin Tests
1
2003
9
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
24
0.010
Why?
Immunoblotting
1
2003
54
0.010
Why?
Plasmids
1
2003
42
0.010
Why?
Models, Genetic
1
2003
31
0.010
Why?
Mice, Transgenic
1
2003
175
0.010
Why?
Time Factors
1
2003
1257
0.010
Why?
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