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Lei Duan

Concepts (286)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
82
3.520
Why?
Drug Resistance, Neoplasm
9
2024
63
3.440
Why?
Proto-Oncogene Proteins c-akt
8
2022
51
2.690
Why?
Imidazoles
7
2019
55
2.600
Why?
Piperazines
7
2019
80
2.560
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
244
2.560
Why?
Receptors, Estrogen
6
2022
61
2.490
Why?
Autophagy
8
2022
30
2.300
Why?
Antineoplastic Agents
9
2024
190
2.260
Why?
Breast Neoplasms
9
2022
414
1.860
Why?
Cell Line, Tumor
19
2024
251
1.850
Why?
Tamoxifen
4
2022
29
1.770
Why?
Lung Neoplasms
4
2023
555
1.720
Why?
Cisplatin
5
2022
53
1.440
Why?
Apoptosis
9
2019
205
1.230
Why?
Triple Negative Breast Neoplasms
3
2024
17
1.210
Why?
Gene Expression Regulation, Neoplastic
3
2024
113
1.070
Why?
Carboxypeptidases
3
2022
6
1.040
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
6
1.020
Why?
Neoplasms
2
2018
241
1.000
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.920
Why?
Glycolysis
3
2018
10
0.820
Why?
Retinoblastoma-Like Protein p130
1
2022
2
0.790
Why?
Signal Transduction
8
2022
451
0.770
Why?
Fatty Acids
1
2021
41
0.750
Why?
Neoplasm Recurrence, Local
1
2022
206
0.750
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.710
Why?
Humans
37
2024
28413
0.680
Why?
Phosphatidylinositol 3-Kinases
2
2021
44
0.640
Why?
Insulin Receptor Substrate Proteins
2
2020
15
0.640
Why?
ErbB Receptors
3
2010
55
0.630
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
2
0.630
Why?
Ketoglutaric Acids
1
2018
2
0.630
Why?
Sp1 Transcription Factor
1
2018
5
0.620
Why?
Proto-Oncogene Proteins c-cbl
5
2010
12
0.610
Why?
Ubiquitin-Protein Ligases
4
2007
30
0.570
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
30
0.570
Why?
Cell Lineage
1
2015
25
0.510
Why?
Protein Kinase Inhibitors
2
2017
50
0.470
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
28
0.460
Why?
Serine Endopeptidases
1
2014
13
0.460
Why?
Sirolimus
1
2014
20
0.460
Why?
Nitric Oxide
1
2014
81
0.450
Why?
Protein Kinases
1
2014
13
0.450
Why?
Mice
12
2022
1475
0.440
Why?
Enzyme Activation
6
2014
121
0.440
Why?
Proto-Oncogene Proteins
2
2004
35
0.440
Why?
MCF-7 Cells
3
2021
13
0.440
Why?
cdc42 GTP-Binding Protein
2
2010
7
0.430
Why?
rac1 GTP-Binding Protein
2
2010
14
0.420
Why?
Mammary Glands, Human
2
2009
7
0.420
Why?
rhoA GTP-Binding Protein
2
2009
9
0.420
Why?
Animals
16
2022
3808
0.410
Why?
Receptors, Glycine
2
2009
2
0.410
Why?
Paclitaxel
2
2022
44
0.400
Why?
RNA, Small Interfering
3
2019
79
0.390
Why?
Cytotoxins
1
2010
2
0.360
Why?
Epithelial Cells
2
2010
81
0.360
Why?
Adherens Junctions
1
2010
4
0.360
Why?
Neoplasm Proteins
1
2010
53
0.360
Why?
Cell Movement
1
2010
82
0.350
Why?
Cell Proliferation
1
2010
181
0.340
Why?
Morphogenesis
1
2009
8
0.340
Why?
Methylation
2
2019
7
0.330
Why?
Osteosarcoma
3
2018
37
0.320
Why?
Histones
2
2019
28
0.320
Why?
Caffeine
1
2009
58
0.320
Why?
Cell Survival
4
2019
119
0.320
Why?
Ubiquitin
5
2007
31
0.320
Why?
Cell Cycle Checkpoints
2
2022
5
0.310
Why?
Kidney
1
2009
174
0.300
Why?
Bone Neoplasms
3
2018
121
0.290
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
10
0.290
Why?
Antineoplastic Agents, Hormonal
2
2021
18
0.280
Why?
Checkpoint Kinase 1
2
2019
5
0.280
Why?
Phosphorylation
6
2016
150
0.270
Why?
RNA Interference
2
2019
36
0.270
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.270
Why?
Mycobacterium tuberculosis
2
2005
17
0.270
Why?
Female
11
2024
15762
0.270
Why?
Gene Knockdown Techniques
2
2018
45
0.270
Why?
Cell Line
6
2013
281
0.270
Why?
Mitochondria
2
2005
71
0.260
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
8
0.240
Why?
Nitrogen
1
2004
4
0.240
Why?
Soil
1
2004
6
0.240
Why?
Receptors, Antigen
1
2004
1
0.230
Why?
Oxygen
2
2015
81
0.230
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.230
Why?
Biomarkers, Tumor
2
2024
202
0.230
Why?
Trastuzumab
2
2022
27
0.230
Why?
Interleukin-6
1
2024
79
0.230
Why?
Histone Deacetylase 1
1
2023
3
0.220
Why?
Retinoblastoma Protein
1
2023
11
0.220
Why?
Benzamides
1
2023
15
0.220
Why?
Lysosomes
1
2003
26
0.210
Why?
Histone Demethylases
1
2022
2
0.210
Why?
Lysine
1
2022
15
0.210
Why?
Mitochondrial Swelling
1
2002
1
0.210
Why?
Cadherins
1
2022
36
0.210
Why?
Estrogen Receptor alpha
1
2022
15
0.210
Why?
CD27 Ligand
1
2022
2
0.210
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.210
Why?
Antigens, CD
1
2022
53
0.210
Why?
Nanoparticles
1
2022
11
0.200
Why?
Antineoplastic Agents, Immunological
1
2022
17
0.200
Why?
Aurora Kinase B
1
2022
2
0.200
Why?
Aurora Kinase A
1
2022
3
0.200
Why?
Glioblastoma
1
2022
9
0.200
Why?
Macrophages
1
2002
109
0.200
Why?
Oxidation-Reduction
1
2021
65
0.190
Why?
Brain Neoplasms
1
2022
89
0.180
Why?
Receptor, ErbB-2
3
2022
50
0.170
Why?
Receptor, IGF Type 1
2
2017
19
0.170
Why?
Autophagy-Related Proteins
1
2019
3
0.160
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.160
Why?
A549 Cells
1
2018
10
0.160
Why?
Pentose Phosphate Pathway
1
2018
2
0.160
Why?
Adenosine
1
2018
8
0.150
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
20
0.150
Why?
Mutation
4
2010
349
0.150
Why?
Heterocyclic Compounds, 3-Ring
2
2017
13
0.150
Why?
Cell Transformation, Neoplastic
2
2009
32
0.150
Why?
Receptors, Somatomedin
1
2017
4
0.140
Why?
Phospholipase C gamma
2
2007
8
0.140
Why?
Epidermal Growth Factor
2
2010
28
0.140
Why?
Loss of Heterozygosity
1
2016
5
0.130
Why?
DNA Mismatch Repair
1
2016
7
0.130
Why?
Biological Assay
1
2016
6
0.130
Why?
Protein-Tyrosine Kinases
2
2007
18
0.130
Why?
Macrolides
1
2015
5
0.130
Why?
Caspase 8
1
2015
9
0.130
Why?
Superoxides
1
2015
24
0.130
Why?
Chloroquine
1
2015
6
0.130
Why?
Microscopy, Electron, Transmission
1
2015
25
0.130
Why?
Cellular Senescence
1
2015
18
0.130
Why?
Microscopy, Electron
1
2015
67
0.130
Why?
Microscopy, Confocal
1
2015
93
0.120
Why?
Flow Cytometry
1
2015
116
0.120
Why?
Phagosomes
1
2014
3
0.120
Why?
Microtubule-Associated Proteins
1
2014
20
0.120
Why?
Nitric Oxide Synthase Type III
1
2014
11
0.120
Why?
DNA Methylation
1
2016
164
0.120
Why?
Protein Processing, Post-Translational
1
2014
39
0.120
Why?
DNA Primers
1
2014
49
0.120
Why?
MAP Kinase Signaling System
1
2014
38
0.110
Why?
Base Sequence
1
2014
102
0.110
Why?
Colorectal Neoplasms
1
2016
113
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
72
0.110
Why?
Models, Biological
1
2016
329
0.110
Why?
DNA Damage
1
2014
28
0.110
Why?
Transfection
3
2020
122
0.110
Why?
Gene Expression Regulation
2
2007
281
0.110
Why?
Membrane Potentials
2
2005
172
0.110
Why?
Cell Adhesion
2
2010
33
0.110
Why?
Aniline Compounds
1
2013
36
0.110
Why?
Triazoles
1
2013
29
0.110
Why?
Dose-Response Relationship, Drug
2
2011
350
0.100
Why?
Triterpenes
1
2011
1
0.090
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
7
0.090
Why?
Ubiquitination
1
2010
15
0.090
Why?
Protein Transport
1
2010
32
0.090
Why?
Actins
1
2010
35
0.090
Why?
Cytoskeleton
1
2010
38
0.090
Why?
Amino Acid Sequence
1
2010
152
0.090
Why?
Molecular Sequence Data
1
2010
191
0.090
Why?
Cell Line, Transformed
1
2009
16
0.080
Why?
Mice, Nude
3
2020
25
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
244
0.080
Why?
Precancerous Conditions
1
2009
25
0.080
Why?
Urodela
1
2008
1
0.080
Why?
Retinal Ganglion Cells
1
2008
2
0.080
Why?
Neural Inhibition
1
2008
8
0.080
Why?
Synaptic Transmission
1
2008
25
0.080
Why?
Glycine
1
2008
12
0.080
Why?
RNA, Messenger
2
2013
304
0.070
Why?
Xenograft Model Antitumor Assays
2
2022
24
0.070
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
5
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
8
0.070
Why?
Neovascularization, Physiologic
1
2007
24
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.070
Why?
Necrosis
2
2005
26
0.070
Why?
Cells, Cultured
2
2008
539
0.060
Why?
Macrophages, Alveolar
1
2005
4
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
41
0.060
Why?
Immune Tolerance
1
2004
14
0.060
Why?
China
1
2004
52
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
16
0.060
Why?
Hydrogen-Ion Concentration
1
2004
136
0.060
Why?
Oncogene Proteins
1
2003
6
0.050
Why?
CHO Cells
1
2003
11
0.050
Why?
Cricetinae
1
2003
36
0.050
Why?
Embryo, Mammalian
1
2003
25
0.050
Why?
Endosomes
1
2003
8
0.050
Why?
Endocytosis
1
2003
17
0.050
Why?
Mice, Knockout
1
2004
320
0.050
Why?
Temperature
1
2003
65
0.050
Why?
Fibroblasts
1
2003
59
0.050
Why?
Blotting, Western
1
2003
148
0.050
Why?
Ionophores
1
2002
2
0.050
Why?
Calcimycin
1
2002
4
0.050
Why?
Ruthenium Red
1
2002
7
0.050
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Cytochrome c Group
1
2002
4
0.050
Why?
Blood Bactericidal Activity
1
2002
5
0.050
Why?
Down-Regulation
1
2003
102
0.050
Why?
Intracellular Membranes
1
2002
21
0.050
Why?
Caspases
1
2002
26
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Calcium-Binding Proteins
1
2002
24
0.050
Why?
Caspase 3
1
2022
20
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Permeability
1
2002
119
0.050
Why?
Gene Expression
1
2003
204
0.050
Why?
Molecular Docking Simulation
1
2022
2
0.050
Why?
Genistein
1
2022
4
0.050
Why?
Calcium Channels
1
2002
107
0.050
Why?
Protein Binding
3
2007
132
0.040
Why?
Structure-Activity Relationship
2
2013
40
0.040
Why?
Luciferases
2
2013
26
0.040
Why?
Disease Models, Animal
1
2020
629
0.040
Why?
Pyrazines
1
2017
10
0.040
Why?
Reproductive History
1
2017
1
0.030
Why?
Receptors, Progesterone
1
2017
25
0.030
Why?
Receptor Cross-Talk
1
2016
6
0.030
Why?
Population Surveillance
1
2017
110
0.030
Why?
Odds Ratio
1
2017
275
0.030
Why?
Tyrosine
2
2007
25
0.030
Why?
Protein Structure, Tertiary
2
2007
60
0.030
Why?
Case-Control Studies
1
2017
604
0.030
Why?
Computer Simulation
1
2016
204
0.030
Why?
Risk Assessment
1
2017
673
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
10
0.030
Why?
Biological Availability
1
2013
19
0.030
Why?
Genes, Reporter
1
2013
24
0.030
Why?
Administration, Oral
1
2013
110
0.030
Why?
Transcription, Genetic
1
2013
108
0.030
Why?
Rats, Sprague-Dawley
1
2013
339
0.030
Why?
Rats
1
2013
678
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
7
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
5
0.020
Why?
Quinazolines
1
2011
16
0.020
Why?
Drug Evaluation, Preclinical
1
2011
31
0.020
Why?
Tumor Burden
1
2011
28
0.020
Why?
Mice, SCID
1
2011
45
0.020
Why?
Male
2
2020
15338
0.020
Why?
Young Adult
1
2017
2102
0.020
Why?
Risk Factors
1
2017
2413
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
93
0.020
Why?
Antibodies, Monoclonal
1
2011
199
0.020
Why?
rho-Associated Kinases
1
2009
5
0.020
Why?
Telomerase
1
2009
9
0.020
Why?
Protein Kinase C
1
2009
52
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
67
0.020
Why?
Retina
1
2008
8
0.020
Why?
Ligands
1
2007
40
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Binding Sites
1
2007
74
0.020
Why?
Laminin
1
2007
8
0.020
Why?
Drug Combinations
1
2007
37
0.020
Why?
Mutagenesis, Site-Directed
1
2007
18
0.020
Why?
Tumor Cells, Cultured
1
2007
120
0.020
Why?
Gene Silencing
1
2007
26
0.020
Why?
Collagen
1
2007
84
0.020
Why?
Enzyme Inhibitors
1
2007
120
0.020
Why?
Proteoglycans
1
2007
136
0.020
Why?
Wound Healing
1
2007
160
0.020
Why?
Receptors, Purinergic P2
1
2005
1
0.020
Why?
Cytochromes c
1
2005
11
0.020
Why?
Adenosine Triphosphate
1
2005
22
0.020
Why?
Cyclosporine
1
2005
13
0.020
Why?
Molecular Conformation
1
2004
10
0.010
Why?
Adult
1
2017
8146
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
10
0.010
Why?
Precipitin Tests
1
2003
10
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
27
0.010
Why?
Immunoblotting
1
2003
57
0.010
Why?
Models, Genetic
1
2003
35
0.010
Why?
Plasmids
1
2003
45
0.010
Why?
Middle Aged
1
2017
9308
0.010
Why?
Mice, Transgenic
1
2003
229
0.010
Why?
Time Factors
1
2003
1499
0.010
Why?
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