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Lei Duan

Concepts (270)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
89
3.750
Why?
Proto-Oncogene Proteins c-akt
8
2022
56
2.880
Why?
Imidazoles
7
2019
72
2.780
Why?
Drug Resistance, Neoplasm
8
2022
75
2.770
Why?
Piperazines
7
2019
90
2.730
Why?
Receptors, Estrogen
6
2022
58
2.690
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
316
2.640
Why?
Autophagy
8
2022
30
2.470
Why?
Antineoplastic Agents
8
2019
218
2.200
Why?
Breast Neoplasms
9
2022
329
2.100
Why?
Tamoxifen
4
2022
30
1.900
Why?
Lung Neoplasms
4
2023
625
1.800
Why?
Cell Line, Tumor
18
2022
265
1.740
Why?
Cisplatin
5
2022
91
1.530
Why?
Apoptosis
8
2019
251
1.230
Why?
Carboxypeptidases
3
2022
6
1.110
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
6
1.100
Why?
Neoplasms
2
2018
247
1.080
Why?
Gene Expression Regulation, Neoplastic
2
2022
100
0.920
Why?
Glycolysis
3
2018
21
0.870
Why?
Retinoblastoma-Like Protein p130
1
2022
2
0.850
Why?
Fatty Acids
1
2021
38
0.810
Why?
Signal Transduction
8
2022
483
0.810
Why?
Neoplasm Recurrence, Local
1
2022
184
0.810
Why?
Proto-Oncogene Proteins c-vav
3
2010
3
0.770
Why?
Phosphatidylinositol 3-Kinases
2
2021
48
0.690
Why?
Insulin Receptor Substrate Proteins
2
2020
14
0.690
Why?
Ketoglutaric Acids
1
2018
2
0.670
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.670
Why?
ErbB Receptors
3
2010
72
0.670
Why?
Sp1 Transcription Factor
1
2018
8
0.660
Why?
Proto-Oncogene Proteins c-cbl
5
2010
12
0.660
Why?
Humans
35
2023
29361
0.660
Why?
Ubiquitin-Protein Ligases
4
2007
36
0.610
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
29
0.610
Why?
Cell Lineage
1
2015
29
0.540
Why?
Protein Kinase Inhibitors
2
2017
47
0.510
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
28
0.500
Why?
Serine Endopeptidases
1
2014
17
0.500
Why?
Sirolimus
1
2014
15
0.500
Why?
Protein Kinases
1
2014
13
0.480
Why?
Nitric Oxide
1
2014
101
0.480
Why?
Proto-Oncogene Proteins
2
2004
31
0.480
Why?
Mice
12
2022
1620
0.470
Why?
MCF-7 Cells
3
2021
17
0.470
Why?
cdc42 GTP-Binding Protein
2
2010
4
0.460
Why?
rac1 GTP-Binding Protein
2
2010
12
0.460
Why?
rhoA GTP-Binding Protein
2
2009
7
0.450
Why?
Mammary Glands, Human
2
2009
6
0.450
Why?
Receptors, Glycine
2
2009
2
0.440
Why?
Paclitaxel
2
2022
74
0.430
Why?
RNA, Small Interfering
3
2019
64
0.420
Why?
Enzyme Activation
5
2014
109
0.420
Why?
Animals
16
2022
4577
0.410
Why?
Cytotoxins
1
2010
5
0.390
Why?
Adherens Junctions
1
2010
4
0.390
Why?
Epithelial Cells
2
2010
88
0.390
Why?
Neoplasm Proteins
1
2010
50
0.380
Why?
Cell Movement
1
2010
105
0.370
Why?
Cell Proliferation
1
2010
202
0.360
Why?
Morphogenesis
1
2009
7
0.360
Why?
Osteosarcoma
3
2018
29
0.350
Why?
Methylation
2
2019
7
0.350
Why?
Histones
2
2019
28
0.350
Why?
Ubiquitin
5
2007
24
0.340
Why?
Caffeine
1
2009
64
0.340
Why?
Cell Survival
4
2019
169
0.340
Why?
Triple Negative Breast Neoplasms
2
2020
15
0.340
Why?
Cell Cycle Checkpoints
2
2022
6
0.330
Why?
Bone Neoplasms
3
2018
102
0.330
Why?
Kidney
1
2009
173
0.310
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
10
0.310
Why?
Antineoplastic Agents, Hormonal
2
2021
18
0.300
Why?
Checkpoint Kinase 1
2
2019
5
0.300
Why?
RNA Interference
2
2019
33
0.290
Why?
Phosphorylation
6
2016
159
0.290
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.290
Why?
Gene Knockdown Techniques
2
2018
41
0.290
Why?
Cell Line
6
2013
299
0.290
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
7
0.260
Why?
Nitrogen
1
2004
4
0.250
Why?
Soil
1
2004
6
0.250
Why?
Receptors, Antigen
1
2004
1
0.250
Why?
Oxygen
2
2015
85
0.250
Why?
Trastuzumab
2
2022
25
0.240
Why?
Histone Deacetylase 1
1
2023
2
0.240
Why?
Retinoblastoma Protein
1
2023
10
0.240
Why?
Benzamides
1
2023
16
0.240
Why?
Lysosomes
1
2003
24
0.230
Why?
Histone Demethylases
1
2022
2
0.230
Why?
Lysine
1
2022
13
0.230
Why?
Cadherins
1
2022
31
0.220
Why?
Estrogen Receptor alpha
1
2022
15
0.220
Why?
CD27 Ligand
1
2022
2
0.220
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.220
Why?
Nanoparticles
1
2022
10
0.220
Why?
Antigens, CD
1
2022
99
0.220
Why?
Antineoplastic Agents, Immunological
1
2022
18
0.220
Why?
Aurora Kinase A
1
2022
2
0.210
Why?
Aurora Kinase B
1
2022
2
0.210
Why?
Female
10
2022
16211
0.210
Why?
Glioblastoma
1
2022
10
0.210
Why?
Oxidation-Reduction
1
2021
73
0.200
Why?
Brain Neoplasms
1
2022
124
0.190
Why?
Receptor, ErbB-2
3
2022
41
0.190
Why?
Receptor, IGF Type 1
2
2017
18
0.180
Why?
Autophagy-Related Proteins
1
2019
2
0.180
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
3
0.180
Why?
A549 Cells
1
2018
9
0.170
Why?
Pentose Phosphate Pathway
1
2018
3
0.170
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
28
0.160
Why?
Adenosine
1
2018
13
0.160
Why?
Heterocyclic Compounds, 3-Ring
2
2017
15
0.160
Why?
Mutation
4
2010
383
0.160
Why?
Cell Transformation, Neoplastic
2
2009
34
0.160
Why?
Receptors, Somatomedin
1
2017
4
0.160
Why?
Phospholipase C gamma
2
2007
9
0.150
Why?
Epidermal Growth Factor
2
2010
29
0.150
Why?
Loss of Heterozygosity
1
2016
4
0.140
Why?
DNA Mismatch Repair
1
2016
6
0.140
Why?
Biological Assay
1
2016
9
0.140
Why?
Protein-Tyrosine Kinases
2
2007
21
0.140
Why?
Macrolides
1
2015
6
0.140
Why?
Caspase 8
1
2015
11
0.140
Why?
Superoxides
1
2015
26
0.140
Why?
Chloroquine
1
2015
12
0.140
Why?
Microscopy, Electron, Transmission
1
2015
30
0.140
Why?
Cellular Senescence
1
2015
19
0.140
Why?
Microscopy, Electron
1
2015
70
0.140
Why?
Microscopy, Confocal
1
2015
116
0.130
Why?
Flow Cytometry
1
2015
199
0.130
Why?
Colorectal Neoplasms
1
2016
82
0.130
Why?
DNA Methylation
1
2016
124
0.130
Why?
Phagosomes
1
2014
3
0.130
Why?
Microtubule-Associated Proteins
1
2014
21
0.130
Why?
Nitric Oxide Synthase Type III
1
2014
17
0.130
Why?
Protein Processing, Post-Translational
1
2014
35
0.130
Why?
DNA Primers
1
2014
52
0.120
Why?
MAP Kinase Signaling System
1
2014
38
0.120
Why?
Nitric Oxide Synthase Type II
1
2014
64
0.120
Why?
Base Sequence
1
2014
135
0.120
Why?
DNA Damage
1
2014
30
0.120
Why?
Models, Biological
1
2016
344
0.120
Why?
Transfection
3
2020
125
0.120
Why?
Gene Expression Regulation
2
2007
284
0.120
Why?
Cell Adhesion
2
2010
43
0.120
Why?
Aniline Compounds
1
2013
41
0.110
Why?
Triazoles
1
2013
30
0.110
Why?
Dose-Response Relationship, Drug
2
2011
437
0.100
Why?
Triterpenes
1
2011
2
0.100
Why?
Estrogen Antagonists
1
2010
3
0.100
Why?
src-Family Kinases
3
2007
8
0.100
Why?
Ubiquitination
1
2010
9
0.100
Why?
Protein Transport
1
2010
38
0.100
Why?
Actins
1
2010
45
0.100
Why?
Cytoskeleton
1
2010
51
0.100
Why?
Amino Acid Sequence
1
2010
193
0.090
Why?
Molecular Sequence Data
1
2010
246
0.090
Why?
Cell Line, Transformed
1
2009
17
0.090
Why?
Mice, Nude
3
2020
34
0.090
Why?
Precancerous Conditions
1
2009
22
0.090
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
290
0.080
Why?
Urodela
1
2008
1
0.080
Why?
Retinal Ganglion Cells
1
2008
3
0.080
Why?
Neural Inhibition
1
2008
10
0.080
Why?
Glycine
1
2008
12
0.080
Why?
Synaptic Transmission
1
2008
46
0.080
Why?
RNA, Messenger
2
2013
323
0.080
Why?
Xenograft Model Antitumor Assays
2
2022
25
0.080
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
3
0.080
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
7
0.080
Why?
Neovascularization, Physiologic
1
2007
22
0.080
Why?
Oncogene Protein v-cbl
2
2003
2
0.070
Why?
Macrophages, Alveolar
1
2005
4
0.070
Why?
Mycobacterium tuberculosis
1
2005
18
0.070
Why?
Plant Development
1
2004
3
0.060
Why?
Mitochondria
1
2005
79
0.060
Why?
Drug Synergism
2
2017
63
0.060
Why?
Immune Tolerance
1
2004
22
0.060
Why?
China
1
2004
59
0.060
Why?
Membrane Potentials
1
2005
189
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
30
0.060
Why?
Hydrogen-Ion Concentration
1
2004
148
0.060
Why?
Oncogene Proteins
1
2003
7
0.060
Why?
CHO Cells
1
2003
12
0.060
Why?
Mice, Knockout
1
2004
304
0.060
Why?
Cricetinae
1
2003
36
0.060
Why?
Endosomes
1
2003
8
0.060
Why?
Embryo, Mammalian
1
2003
31
0.060
Why?
Endocytosis
1
2003
17
0.060
Why?
Temperature
1
2003
76
0.060
Why?
Blotting, Western
1
2003
170
0.060
Why?
Fibroblasts
1
2003
95
0.060
Why?
Down-Regulation
1
2003
112
0.060
Why?
Caspase 9
1
2022
12
0.060
Why?
Caspase 3
1
2022
30
0.060
Why?
Ceramides
1
2022
14
0.060
Why?
Gene Expression
1
2003
226
0.050
Why?
Molecular Docking Simulation
1
2022
1
0.050
Why?
Genistein
1
2022
3
0.050
Why?
Protein Binding
3
2007
127
0.050
Why?
Structure-Activity Relationship
2
2013
44
0.040
Why?
Luciferases
2
2013
24
0.040
Why?
Pyrazines
1
2017
10
0.040
Why?
Disease Models, Animal
1
2020
726
0.040
Why?
Reproductive History
1
2017
1
0.040
Why?
Receptors, Progesterone
1
2017
27
0.040
Why?
Receptor Cross-Talk
1
2016
7
0.040
Why?
Population Surveillance
1
2017
116
0.030
Why?
Odds Ratio
1
2017
285
0.030
Why?
Tyrosine
2
2007
23
0.030
Why?
Biomarkers, Tumor
1
2017
175
0.030
Why?
Protein Structure, Tertiary
2
2007
61
0.030
Why?
Case-Control Studies
1
2017
638
0.030
Why?
Computer Simulation
1
2016
218
0.030
Why?
Risk Assessment
1
2017
678
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
14
0.030
Why?
Biological Availability
1
2013
26
0.030
Why?
Genes, Reporter
1
2013
30
0.030
Why?
Transcription, Genetic
1
2013
108
0.030
Why?
Administration, Oral
1
2013
140
0.030
Why?
Rats, Sprague-Dawley
1
2013
453
0.030
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
7
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
7
0.020
Why?
Drug Evaluation, Preclinical
1
2011
30
0.020
Why?
Tumor Burden
1
2011
28
0.020
Why?
Mice, SCID
1
2011
55
0.020
Why?
Rats
1
2013
858
0.020
Why?
Quinazolines
1
2011
24
0.020
Why?
Young Adult
1
2017
1935
0.020
Why?
Male
2
2020
15637
0.020
Why?
Risk Factors
1
2017
2446
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
113
0.020
Why?
Antibodies, Monoclonal
1
2011
260
0.020
Why?
rho-Associated Kinases
1
2009
6
0.020
Why?
Telomerase
1
2009
9
0.020
Why?
Protein Kinase C
1
2009
44
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
76
0.020
Why?
Retina
1
2008
12
0.020
Why?
Ligands
1
2007
55
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Binding Sites
1
2007
71
0.020
Why?
Laminin
1
2007
8
0.020
Why?
Mutagenesis, Site-Directed
1
2007
19
0.020
Why?
Gene Silencing
1
2007
21
0.020
Why?
Drug Combinations
1
2007
83
0.020
Why?
Tumor Cells, Cultured
1
2007
145
0.020
Why?
Collagen
1
2007
102
0.020
Why?
Enzyme Inhibitors
1
2007
145
0.020
Why?
Cells, Cultured
1
2008
676
0.020
Why?
Wound Healing
1
2007
168
0.020
Why?
Proteoglycans
1
2007
337
0.020
Why?
Receptors, Purinergic P2
1
2005
2
0.020
Why?
Cytochromes c
1
2005
15
0.020
Why?
Necrosis
1
2005
26
0.020
Why?
Adenosine Triphosphate
1
2005
41
0.020
Why?
Cyclosporine
1
2005
15
0.020
Why?
Molecular Conformation
1
2004
15
0.020
Why?
Adult
1
2017
8604
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
10
0.010
Why?
Precipitin Tests
1
2003
12
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
38
0.010
Why?
Immunoblotting
1
2003
55
0.010
Why?
Plasmids
1
2003
44
0.010
Why?
Models, Genetic
1
2003
36
0.010
Why?
Middle Aged
1
2017
9823
0.010
Why?
Mice, Transgenic
1
2003
250
0.010
Why?
Time Factors
1
2003
1618
0.010
Why?
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