"RNA-Binding Protein EWS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.
| Descriptor ID |
D034802
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| MeSH Number(s) |
D12.644.360.650 D12.776.157.142.750 D12.776.157.725.813.750.900 D12.776.476.650 D12.776.624.664.700.913 D12.776.664.962.813.750.900
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| Concept/Terms |
RNA-Binding Protein EWS- RNA-Binding Protein EWS
- EWS, RNA-Binding Protein
- RNA Binding Protein EWS
- EWSR1 Protein
- Protein, EWSR1
- Ewing Sarcoma Breakpoint Region 1 Protein
- EWS Proto-Oncogene Protein
- EWS Proto Oncogene Protein
- Proto-Oncogene Protein, EWS
- Ewing Sarcoma Breakpointregion 1 Protein
- EWS RNA Binding Protein 1
- EWS Protein
|
Below are MeSH descriptors whose meaning is more general than "RNA-Binding Protein EWS".
Below are MeSH descriptors whose meaning is more specific than "RNA-Binding Protein EWS".
This graph shows the total number of publications written about "RNA-Binding Protein EWS" by people in this website by year, and whether "RNA-Binding Protein EWS" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 0 | 1 | 1 |
| 2017 | 0 | 2 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "RNA-Binding Protein EWS" by people in Profiles.
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EWSR1-SMAD3-Positive Fibroblastic Tumor. Int J Surg Pathol. 2021 Apr; 29(2):179-181.
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Desmoplastic small round cell tumor: evaluation of reverse transcription-polymerase chain reaction and fluorescence in situ hybridization as ancillary molecular diagnostic techniques. Virchows Arch. 2017 Nov; 471(5):631-640.
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The spectrum of EWSR1-rearranged neoplasms at a tertiary sarcoma centre; assessing 772 tumour specimens and the value of current ancillary molecular diagnostic modalities. Br J Cancer. 2017 Feb 28; 116(5):669-678.
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Cytomorphology and immunohistochemistry of a recurrent clear cell odontogenic carcinoma with molecular analysis: A case report with review of literature. Diagn Cytopathol. 2015 Sep; 43(9):743-6.