Tumor Necrosis Factor alpha-Induced Protein 3
"Tumor Necrosis Factor alpha-Induced Protein 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A UBIQUITIN editing enzyme that functions as both a ubiquitin ligase and deubiquitinase. It contains several ZINC FINGERS and functions in the immune response and INFLAMMATION by modulating signals from TNF-ALPHA; IL1-BETA; or pathogens via TOLL-LIKE RECEPTORS to terminate NF-KAPPA B activity.
| Descriptor ID |
D000072598
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| MeSH Number(s) |
D08.811.037.750.500 D08.811.277.656.300.887.750 D08.811.464.938.750.813 D12.644.360.950 D12.776.476.938
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tumor Necrosis Factor alpha-Induced Protein 3".
Below are MeSH descriptors whose meaning is more specific than "Tumor Necrosis Factor alpha-Induced Protein 3".
This graph shows the total number of publications written about "Tumor Necrosis Factor alpha-Induced Protein 3" by people in this website by year, and whether "Tumor Necrosis Factor alpha-Induced Protein 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tumor Necrosis Factor alpha-Induced Protein 3" by people in Profiles.
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Expression of TNFAIP3 in intestinal epithelial cells protects from DSS- but not TNBS-induced colitis. Am J Physiol Gastrointest Liver Physiol. 2012 Jul 15; 303(2):G220-7.
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TNFAIP3 maintains intestinal barrier function and supports epithelial cell tight junctions. PLoS One. 2011; 6(10):e26352.
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African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity. J Immunol. 2010 Jun 15; 184(12):7001-9.