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Carl Maki

Concepts (351)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
40
2023
85
10.010
Why?
Imidazoles
15
2019
63
5.530
Why?
Piperazines
15
2019
86
5.430
Why?
Proto-Oncogene Proteins c-akt
8
2022
61
3.820
Why?
Drug Resistance, Neoplasm
10
2024
68
3.320
Why?
Antineoplastic Agents
9
2024
201
2.890
Why?
Proto-Oncogene Proteins c-mdm2
21
2019
34
2.850
Why?
Nuclear Proteins
15
2010
87
2.790
Why?
Cell Line, Tumor
23
2024
270
2.510
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
240
2.480
Why?
Cisplatin
7
2022
61
2.350
Why?
Apoptosis
12
2019
216
2.040
Why?
Receptors, Estrogen
3
2022
65
1.930
Why?
Autophagy
6
2021
34
1.820
Why?
Lung Neoplasms
4
2023
551
1.680
Why?
Neoplasms
6
2018
242
1.540
Why?
Triple Negative Breast Neoplasms
2
2024
17
1.540
Why?
Gene Expression Regulation, Neoplastic
5
2024
125
1.480
Why?
Proto-Oncogene Proteins
10
2005
35
1.420
Why?
Osteosarcoma
8
2018
41
1.420
Why?
Breast Neoplasms
6
2022
411
1.420
Why?
Tamoxifen
3
2022
30
1.360
Why?
Cyclin-Dependent Kinase Inhibitor p21
9
2013
22
1.360
Why?
Insulin Receptor Substrate Proteins
2
2020
17
1.130
Why?
Tumor Suppressor Proteins
7
2010
34
1.120
Why?
Humans
55
2024
27307
1.080
Why?
Active Transport, Cell Nucleus
5
2007
13
1.010
Why?
Transcription Factors
4
2010
169
1.000
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
9
0.980
Why?
Bone Neoplasms
6
2018
131
0.940
Why?
Ubiquitin
4
2007
32
0.920
Why?
Cell Nucleus
8
2010
80
0.900
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.880
Why?
G1 Phase
6
2013
16
0.800
Why?
Mutation
7
2011
353
0.800
Why?
Cellular Senescence
3
2015
19
0.800
Why?
Glycolysis
3
2018
13
0.780
Why?
Retinoblastoma-Like Protein p130
1
2022
3
0.760
Why?
Transfection
12
2020
121
0.760
Why?
Animals
23
2022
3681
0.750
Why?
Colonic Neoplasms
3
2014
56
0.730
Why?
Fatty Acids
1
2021
40
0.730
Why?
Neoplasm Recurrence, Local
1
2022
218
0.720
Why?
Ubiquitins
6
2001
9
0.700
Why?
DNA-Binding Proteins
6
2006
275
0.680
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
11
0.660
Why?
Receptors, Glucocorticoid
2
2012
5
0.660
Why?
Carboxypeptidases
2
2022
8
0.650
Why?
Receptor, IGF Type 1
2
2017
21
0.640
Why?
Mice
13
2022
1449
0.630
Why?
Proto-Oncogene Proteins c-bcl-2
2
2018
19
0.620
Why?
Phosphatidylinositol 3-Kinases
2
2021
47
0.620
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
10
0.620
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.600
Why?
Ketoglutaric Acids
1
2018
3
0.600
Why?
Sp1 Transcription Factor
1
2018
5
0.600
Why?
Adenosine
1
2018
9
0.580
Why?
Protein Conformation
3
2007
69
0.570
Why?
Protein Binding
9
2011
125
0.570
Why?
HSP90 Heat-Shock Proteins
2
2008
5
0.570
Why?
Tetraploidy
2
2014
3
0.570
Why?
G2 Phase
3
2013
5
0.560
Why?
Receptors, Somatomedin
1
2017
5
0.550
Why?
Protein Kinase Inhibitors
2
2017
55
0.550
Why?
Molecular Targeted Therapy
2
2014
33
0.530
Why?
Proteasome Endopeptidase Complex
5
2009
24
0.520
Why?
Loss of Heterozygosity
1
2016
6
0.510
Why?
DNA Mismatch Repair
1
2016
10
0.510
Why?
Signal Transduction
4
2021
455
0.490
Why?
Cell Lineage
1
2015
25
0.490
Why?
Transcription, Genetic
3
2006
124
0.480
Why?
RNA, Small Interfering
4
2019
86
0.480
Why?
Carcinogenesis
1
2014
25
0.450
Why?
Nitric Oxide
2
2014
80
0.450
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
29
0.450
Why?
DNA Methylation
1
2016
165
0.450
Why?
Serine Endopeptidases
1
2014
15
0.450
Why?
Colorectal Neoplasms
1
2016
112
0.440
Why?
Sirolimus
1
2014
20
0.440
Why?
Models, Biological
1
2016
320
0.440
Why?
Protein Kinases
1
2014
13
0.430
Why?
DNA Damage
7
2014
30
0.420
Why?
MCF-7 Cells
3
2021
15
0.420
Why?
Staurosporine
1
2013
2
0.410
Why?
Neoplasm Proteins
2
2003
55
0.410
Why?
Genes, p53
3
2011
18
0.410
Why?
Protein Kinase C-epsilon
1
2012
2
0.390
Why?
Apoptosis Regulatory Proteins
1
2012
11
0.390
Why?
Polyploidy
2
2010
2
0.390
Why?
Paclitaxel
2
2022
51
0.390
Why?
Ultraviolet Rays
4
2001
8
0.390
Why?
HCT116 Cells
4
2014
11
0.370
Why?
Gene Knockdown Techniques
3
2018
46
0.350
Why?
Cell Cycle
2
2010
34
0.340
Why?
Intracellular Signaling Peptides and Proteins
1
2010
54
0.330
Why?
Mitosis
2
2008
7
0.330
Why?
Phosphorylation
4
2016
147
0.330
Why?
Zinc Fingers
2
2000
12
0.330
Why?
Cytoskeleton
1
2010
34
0.330
Why?
RNA Interference
3
2019
42
0.330
Why?
Cell Movement
1
2010
82
0.320
Why?
Cell Line
7
2009
292
0.320
Why?
Puromycin
1
2009
1
0.320
Why?
Intranuclear Inclusion Bodies
1
2009
2
0.320
Why?
HSP70 Heat-Shock Proteins
1
2009
8
0.310
Why?
Cyclin-Dependent Kinases
3
2013
5
0.310
Why?
Methylation
2
2019
13
0.310
Why?
Immunoblotting
6
2007
55
0.310
Why?
Enzyme Activation
3
2014
119
0.310
Why?
DNA
7
2008
102
0.310
Why?
Histones
2
2019
36
0.310
Why?
Genetic Vectors
1
2009
59
0.310
Why?
DNA Replication
1
2008
10
0.300
Why?
Tumor Cells, Cultured
10
2003
130
0.300
Why?
Gene Expression Regulation
2
2010
290
0.300
Why?
Reactive Oxygen Species
1
2009
117
0.300
Why?
Cell Cycle Checkpoints
2
2022
7
0.300
Why?
Micronuclei, Chromosome-Defective
1
2008
1
0.300
Why?
Benzoquinones
1
2008
2
0.300
Why?
Lactams, Macrocyclic
1
2008
5
0.300
Why?
Cell Survival
4
2019
121
0.290
Why?
Antineoplastic Agents, Hormonal
2
2021
19
0.280
Why?
Nuclear Export Signals
1
2007
1
0.270
Why?
Oxygen
3
2015
66
0.270
Why?
Checkpoint Kinase 1
2
2019
7
0.270
Why?
Hodgkin Disease
1
2006
19
0.260
Why?
Base Sequence
7
2014
108
0.250
Why?
Heterocyclic Compounds, 3-Ring
2
2017
14
0.250
Why?
Protein Processing, Post-Translational
3
2014
41
0.250
Why?
CDC2-CDC28 Kinases
1
2005
1
0.240
Why?
Gamma Rays
3
2012
15
0.240
Why?
Cell Cycle Proteins
1
2005
17
0.240
Why?
Oxidative Stress
1
2005
97
0.230
Why?
RNA, Messenger
7
2012
317
0.230
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.220
Why?
Cytoplasm
4
2007
37
0.220
Why?
DNA Primers
4
2014
52
0.220
Why?
Promyelocytic Leukemia Protein
3
2010
3
0.220
Why?
Interleukin-6
1
2024
75
0.220
Why?
Protein Structure, Tertiary
4
2006
62
0.210
Why?
Histone Deacetylase 1
1
2023
3
0.210
Why?
Retinoblastoma Protein
1
2023
11
0.210
Why?
Benzamides
1
2023
15
0.210
Why?
Female
6
2024
15334
0.210
Why?
Clone Cells
2
2014
11
0.210
Why?
Histone Demethylases
1
2022
3
0.200
Why?
Mice, Knockout
6
2007
311
0.200
Why?
Lysine
1
2022
14
0.200
Why?
Estrogen Receptor alpha
1
2022
16
0.200
Why?
Cadherins
1
2022
35
0.200
Why?
CD27 Ligand
1
2022
2
0.200
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.200
Why?
Antigens, CD
1
2022
53
0.200
Why?
Nanoparticles
1
2022
11
0.200
Why?
Trastuzumab
1
2022
26
0.200
Why?
Antineoplastic Agents, Immunological
1
2022
16
0.190
Why?
Biomarkers, Tumor
1
2024
208
0.190
Why?
Aurora Kinase B
1
2022
3
0.190
Why?
Aurora Kinase A
1
2022
4
0.190
Why?
Ribosomal Proteins
3
1990
3
0.190
Why?
Oxidation-Reduction
1
2021
65
0.180
Why?
Down-Regulation
2
2001
109
0.180
Why?
Cells, Cultured
6
2007
527
0.180
Why?
CDC2 Protein Kinase
2
2013
3
0.180
Why?
Cysteine Endopeptidases
2
2003
11
0.180
Why?
Cyclin B
2
2013
4
0.180
Why?
Cyclin A
2
2013
4
0.180
Why?
Recombinant Fusion Proteins
3
2006
30
0.180
Why?
Alkylating Agents
1
2001
1
0.180
Why?
Multienzyme Complexes
2
2003
30
0.180
Why?
Mice, Nude
1
2020
25
0.170
Why?
Tumor Protein p73
3
2006
3
0.170
Why?
Cyclins
2
1997
5
0.170
Why?
Dexamethasone
2
2012
34
0.160
Why?
Autophagy-Related Proteins
1
2019
4
0.160
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.160
Why?
Plasmids
3
2005
44
0.160
Why?
A549 Cells
1
2018
11
0.150
Why?
Pentose Phosphate Pathway
1
2018
3
0.150
Why?
Caspase 3
2
2022
20
0.150
Why?
Disease Models, Animal
1
2020
606
0.140
Why?
Drug Synergism
1
2017
39
0.140
Why?
Pyrazines
1
2017
12
0.140
Why?
Embryo, Mammalian
2
2007
25
0.140
Why?
Fibroblasts
2
2007
57
0.130
Why?
DNA Repair
2
2010
8
0.130
Why?
Receptor Cross-Talk
1
2016
7
0.130
Why?
Immunoprecipitation
2
2007
22
0.130
Why?
Flow Cytometry
2
2015
112
0.130
Why?
Biological Assay
1
2016
7
0.130
Why?
Macrolides
1
2015
6
0.120
Why?
Caspase 8
1
2015
10
0.120
Why?
Superoxides
1
2015
24
0.120
Why?
Chloroquine
1
2015
7
0.120
Why?
Microscopy, Electron, Transmission
1
2015
26
0.120
Why?
Microscopy, Electron
1
2015
63
0.120
Why?
Microscopy, Confocal
1
2015
88
0.120
Why?
Diploidy
1
2014
2
0.120
Why?
G1 Phase Cell Cycle Checkpoints
1
2014
2
0.120
Why?
Fluorescent Antibody Technique
3
2003
58
0.110
Why?
Phagosomes
1
2014
3
0.110
Why?
Microtubule-Associated Proteins
1
2014
19
0.110
Why?
Nitric Oxide Synthase Type III
1
2014
11
0.110
Why?
MAP Kinase Signaling System
1
2014
38
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
69
0.110
Why?
Interferon-gamma
4
2003
89
0.110
Why?
Fatty Acids, Unsaturated
2
2005
12
0.110
Why?
Genes, Tumor Suppressor
2
2004
11
0.100
Why?
Leupeptins
2
2006
3
0.100
Why?
Cysteine Proteinase Inhibitors
2
2006
6
0.100
Why?
Caspase 7
1
2012
2
0.100
Why?
Cell Line, Transformed
1
2012
17
0.100
Why?
Proto-Oncogene Proteins c-myc
1
2012
15
0.100
Why?
Hydrocortisone
1
2012
39
0.100
Why?
Protein Synthesis Inhibitors
2
2005
6
0.090
Why?
Cycloheximide
2
2005
7
0.090
Why?
Anti-Inflammatory Agents
1
2012
77
0.090
Why?
Telomere
1
2010
7
0.090
Why?
Multiprotein Complexes
1
2010
4
0.090
Why?
Protein Transport
1
2010
33
0.090
Why?
Drosophila
1
1990
8
0.090
Why?
Dendritic Cells
2
2001
36
0.090
Why?
Exons
2
2006
33
0.080
Why?
TOR Serine-Threonine Kinases
1
2010
13
0.080
Why?
Stress Fibers
1
2010
1
0.080
Why?
Pseudopodia
1
2010
5
0.080
Why?
Focal Adhesions
1
2010
4
0.080
Why?
Actins
1
2010
35
0.080
Why?
Neoplasm Invasiveness
1
2010
93
0.080
Why?
Cell Proliferation
1
2010
184
0.080
Why?
SUMO-1 Protein
1
2009
1
0.080
Why?
Protein Folding
1
2009
19
0.080
Why?
Gene Expression
2
2003
201
0.080
Why?
Cyclin B1
1
2008
1
0.080
Why?
Time Factors
2
2005
1444
0.080
Why?
HT29 Cells
1
2008
8
0.070
Why?
Cell Division
1
2008
82
0.070
Why?
Binding Sites
2
2005
74
0.070
Why?
Male
2
2020
14887
0.070
Why?
Molecular Conformation
1
2007
10
0.070
Why?
Proteasome Inhibitors
1
2006
2
0.070
Why?
Luciferases
1
2006
28
0.070
Why?
Genes, Reporter
1
2006
25
0.070
Why?
Response Elements
1
2006
16
0.070
Why?
Sequence Deletion
1
2006
16
0.060
Why?
Glucocorticoids
1
2006
68
0.060
Why?
Radiation, Ionizing
1
2005
2
0.060
Why?
Nucleic Acid Synthesis Inhibitors
1
2005
5
0.060
Why?
Etoposide
1
2005
27
0.060
Why?
Liver Neoplasms
1
2007
103
0.060
Why?
Cyclin E
1
2005
1
0.060
Why?
Cyclin-Dependent Kinase 2
1
2005
1
0.060
Why?
Serine
1
2005
10
0.060
Why?
Densitometry
1
2005
9
0.060
Why?
Amino Acid Motifs
1
2005
20
0.060
Why?
HeLa Cells
1
2005
41
0.060
Why?
Polymerase Chain Reaction
2
2003
119
0.060
Why?
Antifungal Agents
1
2005
43
0.060
Why?
Cloning, Molecular
2
2003
29
0.060
Why?
Protein Isoforms
1
2004
45
0.060
Why?
Baculoviridae
1
2003
1
0.050
Why?
Spodoptera
1
2003
1
0.050
Why?
Immunosorbent Techniques
1
2003
3
0.050
Why?
Glutathione Transferase
1
2003
4
0.050
Why?
Mutagenesis
1
2003
11
0.050
Why?
Saccharomyces cerevisiae Proteins
1
2003
14
0.050
Why?
Structure-Activity Relationship
1
2003
37
0.050
Why?
Gene Deletion
1
2003
41
0.050
Why?
Cyclic AMP Response Element-Binding Protein
1
2003
39
0.050
Why?
Peptide Fragments
1
2003
76
0.050
Why?
Interleukin-12
2
2001
40
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Xenograft Model Antitumor Assays
1
2022
22
0.050
Why?
Receptor, ErbB-2
1
2022
52
0.050
Why?
Chickens
1
2002
35
0.050
Why?
Receptors, Interleukin-2
1
2001
7
0.050
Why?
Interleukin-15
1
2001
9
0.050
Why?
Precipitin Tests
1
2001
12
0.050
Why?
Stress, Physiological
1
2001
15
0.050
Why?
Epitopes
1
2001
44
0.050
Why?
Microscopy, Fluorescence
1
2001
79
0.050
Why?
Thymus Gland
1
2001
11
0.050
Why?
Phosphoproteins
1
2001
26
0.050
Why?
Methyl Methanesulfonate
1
2001
1
0.040
Why?
Phosphoserine
1
2001
5
0.040
Why?
T-Lymphocyte Subsets
1
2001
41
0.040
Why?
Mitomycin
1
2001
10
0.040
Why?
Salmon
1
2000
1
0.040
Why?
Macrophages
1
2001
116
0.040
Why?
Glycoproteins
1
2001
49
0.040
Why?
Restriction Mapping
2
1990
3
0.040
Why?
CD8-Positive T-Lymphocytes
1
2001
116
0.040
Why?
Cell Culture Techniques
1
2000
33
0.040
Why?
Ligases
1
1999
7
0.040
Why?
Oncogene Proteins, Viral
1
1999
5
0.040
Why?
Repressor Proteins
1
1999
38
0.040
Why?
CD8 Antigens
1
1999
11
0.040
Why?
Intestinal Mucosa
1
2001
176
0.040
Why?
Point Mutation
1
1999
25
0.040
Why?
S Phase
1
1998
11
0.040
Why?
Enzyme Inhibitors
1
1997
117
0.030
Why?
Acetylcysteine
1
1996
14
0.030
Why?
Molecular Sequence Data
3
1995
194
0.030
Why?
Introns
2
2001
17
0.030
Why?
Computer Simulation
1
2016
195
0.030
Why?
Sequence Homology, Nucleic Acid
2
1990
7
0.030
Why?
Amino Acid Sequence
2
1990
154
0.020
Why?
Aniline Compounds
1
1990
35
0.020
Why?
Killer Cells, Natural
2
2001
41
0.020
Why?
Mice, Inbred C57BL
2
2001
454
0.020
Why?
Multigene Family
1
1989
9
0.020
Why?
Biological Evolution
1
1989
9
0.020
Why?
Drosophila melanogaster
1
1989
14
0.020
Why?
Blotting, Western
2
1998
153
0.020
Why?
Interleukin-2 Receptor beta Subunit
1
2001
1
0.010
Why?
Receptors, Interleukin-15
1
2001
2
0.010
Why?
Receptors, Interleukin
1
2001
3
0.010
Why?
CD40 Antigens
1
2001
6
0.010
Why?
Histocompatibility Antigens Class II
1
2001
6
0.010
Why?
Interleukin-2
1
2001
22
0.010
Why?
Receptors, Antigen, T-Cell, gamma-delta
1
2001
1
0.010
Why?
Lymphocyte Culture Test, Mixed
1
2001
4
0.010
Why?
Transgenes
1
2001
12
0.010
Why?
Mice, Inbred C3H
1
2001
20
0.010
Why?
Interferon Regulatory Factor-1
1
2001
7
0.010
Why?
Gene Transfer Techniques
1
2001
30
0.010
Why?
DNA Probes
1
2001
7
0.010
Why?
Mice, Inbred BALB C
1
2001
103
0.010
Why?
Transcriptional Activation
1
2001
37
0.010
Why?
Cattle
1
2001
124
0.010
Why?
Lymphocyte Activation
1
2001
84
0.010
Why?
In Vitro Techniques
1
2001
169
0.010
Why?
Cell Differentiation
1
2001
137
0.010
Why?
Up-Regulation
1
2001
185
0.010
Why?
Intercellular Signaling Peptides and Proteins
1
2001
56
0.010
Why?
Mice, Transgenic
1
2001
225
0.010
Why?
Tumor Suppressor Protein p14ARF
1
1999
1
0.010
Why?
Cell Hypoxia
1
1999
10
0.010
Why?
Ubiquitin-Protein Ligases
1
1999
28
0.010
Why?
Transposases
1
1999
1
0.010
Why?
Listeria monocytogenes
1
1999
3
0.010
Why?
Proteins
1
1999
63
0.010
Why?
Spleen
1
1999
33
0.010
Why?
Mitotic Index
1
1998
6
0.010
Why?
Adenocarcinoma
1
1998
140
0.010
Why?
Carcinoma, Squamous Cell
1
1998
172
0.010
Why?
Autoradiography
1
1995
6
0.010
Why?
Radiation Tolerance
1
1995
6
0.010
Why?
Xenopus laevis
1
1990
4
0.010
Why?
Electrophoresis, Gel, Two-Dimensional
1
1990
9
0.010
Why?
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