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Jeffrey Allen Borgia

TitleAssociate Professor
InstitutionRush University, Rush Medical College
DepartmentAnatomy and Cell Biology
AddressChicago IL 60612
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    Collapse Overview 
    Collapse overview
    Director, RUSH University Cancer Center Biorepository
    Director, RUSH Biomarker Development Core

    My Scopus ID is 6602993443
    My NIH COMMONS name is JBORGIA

    Research Areas:
    My research is primarily focused on the development of novel diagnostic tests based on "Omic"-level profiling of patient specimens and/or mechanistic insights for pathophysiology. As the director of the Rush University Medical Center | Cancer Center Biorepository I oversee the collection and annotation of patient specimens to support translational research projects and clinical trials that are ongoing in the RUSH University Cancer Center. My role as the director of the RUSH Biomarker Development Core permits me to facilitate the administration of state-of-the art services aimed at the discovery and development of novel biomarkers aimed at altering treatment decisions in the clinics, ranging from early cancer detection to personalized treatment selection for patients. Platforms supported include quantitative mass spectrometry and custom Luminex immunoassays that, combined with accompanying laboratory automation and skilled personnel, generate very high-throughput biomarker discovery, assay development (with analytical validation), and routine specimen processing.

    My Faculty Profile at Rush University Medical Center:
    https://www.rushu.rush.edu/faculty/jeffrey-borgia-phd

    My Laboratory:
    https://www.rushu.rush.edu/research/departmental-research/cell-molecular-medicine-research/laboratory-jeffrey-borgia-phd

    RUSH Cancer Center Biorepository Resource:
    https://www.rushu.rush.edu/research-rush-university/rush-core-laboratories/rush-cancer-center-biorepository-resource

    RUSH Biomarker Development Core:
    https://www.rushu.rush.edu/research-rush-university/rush-core-laboratories/rush-biomarker-development-core

    My NCBI Bibliography:
    https://www.ncbi.nlm.nih.gov/myncbi/browse/collection/40797756/?sort=date&direction=descending

    My Scopus:
    https://www.scopus.com/authid/detail.uri?authorId=6602993443

    Education:
    PhD, University of Minnesota, Twin Cities
    BS, Eckerd College

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chen S, Liu F, Fu Y, Deng CK, Borgia JA, Ayman AG, Nasu M, Jijiwa M, Yang H, Gong T, Wang J, Ling Z, Wang X, Wang H, Chu Q, Deng Y. A prospective multi-cohort study identifies and validates a 5-gene peripheral blood signature predictive of immunotherapy response in non-small cell lung cancer. Mol Cancer. 2024 Nov 06; 23(1):247. PMID: 39506771; PMCID: PMC11539423.
      Citations:    
    2. Aboushaala K, Chee AV, Adnan D, Toro SJ, Singh H, Savoia A, Dhillon ES, Yuh C, Dourdourekas J, Patel IK, Vucicevic R, Espinoza-Orias AA, Martin JT, Oh C, Keshavarzian A, Albert HB, Karppinen J, Kocak M, Wong AYL, Goldberg EJ, Phillips FM, Colman MW, Williams FMK, Borgia JA, Naqib A, Green SJ, Forsyth CB, An HS, Samartzis D. Gut microbiome dysbiosis is associated with lumbar degenerative spondylolisthesis in symptomatic patients. JOR Spine. 2024 Dec; 7(4):e70005. PMID: 39398942; PMCID: PMC11467165.
      Citations:    
    3. Bonomi P, Moudgalya H, Gomez SL, Shah P, Basu S, Batus M, Martinka LB, Abdelkader A, Tzameli I, Cobain S, Collins S, Keliher EJ, Breen DM, Calle RA, Fidler MJ, Borgia JA. Frequency of weight and body composition increases in advanced non-small cell lung cancer patients during first line therapy. J Cachexia Sarcopenia Muscle. 2024 Dec; 15(6):2311-2322. PMID: 39289919; PMCID: PMC11634467.
      Citations:    
    4. Halloway S, Volgman AS, Barnes LL, Schoeny ME, Wilbur J, Pressler SJ, Laddu D, Phillips SA, Vispute S, Hall G, Shakya S, Goodyke M, Auger C, Cagin K, Borgia JA, Arvanitakis ZA. The MindMoves Trial: Cross-Sectional Analyses of Baseline Vascular Risk and Cognition in Older Women with Cardiovascular Disease. J Alzheimers Dis. 2024; 100(4):1407-1416. PMID: 39031356.
      Citations:    
    5. Chaudhry T, Krishnan V, Donaldson AE, Palmisano ZM, Basu S, Geissen NM, Karush JM, Alex GC, Borgia JA, Liptay MJ, Seder CW. Conditional survival analysis of patients with resected non-small cell lung cancer. JTCVS Open. 2023 Dec; 16:948-959. PMID: 38204712; PMCID: PMC10775048.
      Citations:    
    6. Stephan JT, Mehta P, Zepeda DL, Uppal M, Basu S, Liptay MJ, Borgia JA, Geissen N, Shah P, Karush J, Alex G, Seder CW. Low-Dose Computed Tomography Scan Features Are Associated With Annual Risk of Hospitalization. Ann Thorac Surg Short Rep. 2023 Dec; 1(4):558-561. PMID: 39790682; PMCID: PMC11708268.
      Citations:    
    7. Khaliq AM, Erdogan C, Kurt Z, Turgut SS, Grunvald MW, Rand T, Khare S, Borgia JA, Hayden DM, Pappas SG, Govekar HR, Kam AE, Reiser J, Turaga K, Radovich M, Zang Y, Qiu Y, Liu Y, Fishel ML, Turk A, Gupta V, Al-Sabti R, Subramanian J, Kuzel TM, Sadanandam A, Waldron L, Hussain A, Saleem M, El-Rayes B, Salahudeen AA, Masood A, Khaliq AM, Erdogan C, Kurt Z, Turgut SS, Grunvald MW, Rand T, Khare S, Borgia JA, Hayden DM, Pappas SG, Govekar HR, Kam AE, Reiser J, Turaga K, Radovich M, Zang Y, Qiu Y, Liu Y, Fishel ML, Turk A, Gupta V, Al-Sabti R, Subramanian J, Kuzel TM, Sadanandam A, Waldron L, Hussain A, Saleem M, El-Rayes B, Salahudeen AA, Masood A. Correction: Refining colorectal cancer classification and clinical stratification through a single-cell atlas. Genome Biol. 2022 Jul 13; 23(1):156. PMID: 35831907; PMCID: PMC9277898.
      Citations:    
    8. Chukkapalli V, Gordon LI, Venugopal P, Borgia JA, Karmali R, Chukkapalli V, Gordon LI, Venugopal P, Borgia JA, Karmali R. Metabolic changes associated with metformin potentiates Bcl-2 inhibitor, Venetoclax, and CDK9 inhibitor, BAY1143572 and reduces viability of lymphoma cells. Oncotarget. 2018 Apr 20; 9(30):21166-21181. PMID: 29765528; PMCID: PMC5940409.
      Citations:    
    9. Fidler MJ, Frankenberger C, Seto R, Lobato GC, Fhied CL, Sayidine S, Basu S, Pool M, Karmali R, Batus M, Lie WR, Hayes D, Mistry J, Bonomi P, Borgia JA. Differential expression of circulating biomarkers of tumor phenotype and outcomes in previously treated non-small cell lung cancer patients receiving erlotinib vs. cytotoxic chemotherapy. Oncotarget. 2017 Aug 29; 8(35):58108-58121. PMID: 28938541.
      Citations:    
    10. Karmali R, Alrifai T, Fughhi IAM, Ng R, Chukkapalli V, Shah P, Basu S, Nathan S, Szymanski-Grant K, Gordon LI, Venugopal P, Penedo FJ, Borgia JA. Impact of cachexia on outcomes in aggressive lymphomas. Ann Hematol. 2017 Jun; 96(6):951-956. PMID: 28417157.
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    11. Bonomi P, Batus M, Fidler MJ, Borgia JA. Practical and theoretical implications of weight gain in advanced non-small cell lung cancer patients. Ann Transl Med. 2017 Mar; 5(6):152. PMID: 28462232.
      Citations:    
    12. Derman BA, Macklis JN, Azeem MS, Sayidine S, Basu S, Batus M, Esmail F, Borgia JA, Bonomi P, Fidler MJ. Relationships between longitudinal neutrophil to lymphocyte ratios, body weight changes, and overall survival in patients with non-small cell lung cancer. BMC Cancer. 2017 02 16; 17(1):141. PMID: 28209123.
      Citations:    
    13. Lopez-Soler RI, Borgia JA, Kanangat S, Fhied CL, Conti DJ, Constantino D, Ata A, Chan R, Wang Z. Anti-vimentin Antibodies Present at the Time of Transplantation May Predict Early Development of Interstitial Fibrosis/Tubular Atrophy. Transplant Proc. 2016 Jul-Aug; 48(6):2023-33. PMID: 27569939.
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    14. Gu J, Lu Y, Li F, Qiao L, Wang Q, Li N, Borgia JA, Deng Y, Lei G, Zheng Q. Identification and characterization of the novel Col10a1 regulatory mechanism during chondrocyte hypertrophic differentiation. Cell Death Dis. 2014 Oct 16; 5:e1469. PMID: 25321476.
      Citations:    
    15. Farlow EC, Vercillo MS, Coon JS, Basu S, Kim AW, Faber LP, Warren WH, Bonomi P, Liptay MJ, Borgia JA. A multi-analyte serum test for the detection of non-small cell lung cancer. Br J Cancer. 2010 Oct 12; 103(8):1221-8. PMID: 20859284.
      Citations:    
    16. Borgia JA, Malkar NB, Abbasi HU, Fields GB. Difficulties encountered during glycopeptide syntheses. J Biomol Tech. 2001 Sep; 12(3):44-68. PMID: 19499072.
      Citations:    
    17. Borgia JA, Fields GB. Chemical synthesis of proteins. Trends Biotechnol. 2000 Jun; 18(6):243-51. PMID: 10802559.
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