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Joshua Melson

TitleAdjunct Professor
InstitutionRush University, Rush Medical College
DepartmentDigestive Diseases and Nutrition
AddressChicago IL 60612
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    My Scopus ID is 6507137568.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Djinbachian R, Pohl H, Rex DK, Levenick JM, Pleskow DK, Wallace MB, Khashab M, Singh A, Melson J, Yang D, Gavric A, von Renteln D. Thermal ablation after endoscopic mucosal resection of large colorectal polyps: not only the margins, but also the base? Gut. 2023 Dec 07; 73(1):12-15. PMID: 37816588.
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    2. Bresalier RS, Senore C, Young GP, Allison J, Benamouzig R, Benton S, Bossuyt PMM, Caro L, Carvalho B, Chiu HM, Coup? VMH, de Klaver W, de Klerk CM, Dekker E, Dolwani S, Fraser CG, Grady W, Guittet L, Gupta S, Halloran SP, Haug U, Hoff G, Itzkowitz S, Kortlever T, Koulaouzidis A, Ladabaum U, Lauby-Secretan B, Leja M, Levin B, Levin TR, Macrae F, Meijer GA, Melson J, O'Morain C, Parry S, Rabeneck L, Ransohoff DF, S?enz R, Saito H, Sanduleanu-Dascalescu S, Schoen RE, Selby K, Singh H, Steele RJC, Sung JJY, Symonds EL, Winawer SJ. An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles. Gut. 2023 10; 72(10):1904-1918. PMID: 37463757.
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    3. Van J, Alsayid M, Ma K, Vemulapalli K, Rex D, Melson J. Impact of Cold Snare vs Cold Forceps Resection of Diminutive Adenomas on Segmental Incomplete Resection Rate. Am J Gastroenterol. 2023 08 01; 118(8):1410-1418. PMID: 37040556.
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    4. Melson J. Monitoring colonoscopy screening program quality at the provider level, the institution level, and beyond. Gastrointest Endosc. 2022 Nov 09. PMID: 36371237.
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    5. Post Z, Melson J. Early steps on the pathway to develop quality metrics that have an impact on postendoscopy upper gastrointestinal cancer rates. Gastrointest Endosc. 2022 09; 96(3):476-478. PMID: 35850861.
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    6. Gebrekiristos M, Melson J, Jiang A, Buckingham L. DNA methylation and miRNA expression in colon adenomas compared with matched normal colon mucosa and carcinomas. Int J Exp Pathol. 2022 06; 103(3):74-82. PMID: 35229372.
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    7. Melson J. The pathway to monitoring quality of care for patients with adenomatous oligopolyposis of unknown etiology. Endoscopy. 2022 07; 54(7):698-699. PMID: 35213898.
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    8. Hamoudah T, Vemulapalli KC, Alsayid M, Van J, Ma K, Jakate S, Rex DK, Melson J. Risk of total metachronous advanced neoplasia in patients with both small tubular adenomas and serrated polyps. Gastrointest Endosc. 2022 07; 96(1):95-100. PMID: 35183543.
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    9. Pannala R, Krishnan K, Watson RR, Vela MF, Abu Dayyeh BK, Bhatt A, Bhutani MS, Bucobo JC, Chandrasekhara V, Copland AP, Jirapinyo P, Kumta NA, Law RJ, Maple JT, Melson J, Parsi MA, Rahimi EF, Saumoy M, Sethi A, Trikudanathan G, Trindade AJ, Yang J, Lichtenstein DR. Devices for esophageal function testing. Gastrointest Endosc. 2022 01; 95(1):27-29. PMID: 34696917.
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    10. Post Z, Melson J. Equal Pay for Equal Screening: Impact of Patient and Provider Gender on Reimbursement for Screening Colonoscopy. Dig Dis Sci. 2022 03; 67(3):739-741. PMID: 34114157.
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    11. Jiang AC, Buckingham L, Bishehsari F, Sutherland S, Ma K, Melson JE. Correlation of LINE-1 Hypomethylation With Size and Pathologic Extent of Dysplasia in Colorectal Tubular Adenomas. Clin Transl Gastroenterol. 2021 06 01; 12(6):e00369. PMID: 34060495.
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    12. Jirapinyo P, Sethi A, Abu Dayyeh BK, Bhutani MS, Chandrasekhara V, Kumta NA, Melson J, Pannala R, Rahimi EF, Trikudanathan G, Maple JT, Lichtenstein DR. Devices and techniques for flexible endoscopic management of Zenker's diverticulum (with videos). Gastrointest Endosc. 2021 07; 94(1):3-13. PMID: 33926711.
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    13. Barlass U, Melson J. Rev up your engines: a new approach to access the deep small bowel by motorized spiral enteroscopy. Gastrointest Endosc. 2021 06; 93(6):1371-1372. PMID: 33691976.
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    14. Melson J, Trikudanathan G, Abu Dayyeh BK, Bhutani MS, Chandrasekhara V, Jirapinyo P, Krishnan K, Kumta NA, Pannala R, Parsi MA, Sethi A, Trindade AJ, Watson RR, Maple JT, Lichtenstein DR. Video capsule endoscopy. Gastrointest Endosc. 2021 04; 93(4):784-796. PMID: 33642034.
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    15. Park E, Barge W, Kramer J, Alajati B, Jakate S, Cimbaluk D, Giusto D, Ritz E, Bishehsari F, Lee S, Singh S, Losurdo J, Brown M, DeMeo M, Abraham R, Ma K, Melson J. Interobserver reliability of methods to determine complete resection of adenomas in colonoscopy. Endoscopy. 2021 12; 53(12):1250-1255. PMID: 33285582.
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    16. Alsayid M, Van J, Ma K, Melson J. Segmental metachronous adenoma rate as a metric for monitoring incomplete resection in a colonoscopy screening program. Gastrointest Endosc. 2021 08; 94(2):347-354. PMID: 33561485.
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    17. Krishnan K, Bhutani MS, Aslanian HR, Melson J, Navaneethan U, Pannala R, Parsi MA, Schulman AR, Sethi A, Sullivan S, Trikudanathan G, Trindade AJ, Watson RR, Maple JT, Lichtenstein DR. Enhanced EUS imaging (with videos). Gastrointest Endosc. 2021 02; 93(2):323-333. PMID: 33129492.
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    18. Musher BL, Melson JE, Amato G, Chan D, Hill M, Khan I, Kochuparambil ST, Lyons SE, Orsini J, Pedersen SK, Robb B, Saltzman J, Silinsky J, Gaur S, Tuck MK, LaPointe LC, Young GP. Evaluation of Circulating Tumor DNA for Methylated BCAT1 and IKZF1 to Detect Recurrence of Stage II/Stage III Colorectal Cancer (CRC). Cancer Epidemiol Biomarkers Prev. 2020 12; 29(12):2702-2709. PMID: 32958500.
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    19. Schulman AR, Watson RR, Abu Dayyeh BK, Bhutani MS, Chandrasekhara V, Jirapinyo P, Krishnan K, Kumta NA, Melson J, Pannala R, Parsi MA, Trikudanathan G, Trindade AJ, Maple JT, Lichtenstein DR. Endoscopic devices and techniques for the management of bariatric surgical adverse events (with videos). Gastrointest Endosc. 2020 Sep; 92(3):492-507. PMID: 32800313.
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    20. Ma K, Melson J. Connecting colonoscopy quality improvement initiatives with reduced rates of interval colorectal cancers. Gastrointest Endosc. 2020 08; 92(2):365-367. PMID: 32703370.
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    21. Parsi MA, Jirapinyo P, Abu Dayyeh BK, Bhutani MS, Chandrasekhara V, Krishnan K, Kumta NA, Melson J, Pannala R, Trikudanathan G, Trindade AJ, Sethi A, Watson RR, Maple JT, Lichtenstein DR. Techniques and devices for the endoscopic treatment of gastroparesis (with video). Gastrointest Endosc. 2020 Sep; 92(3):483-491. PMID: 32684298.
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    22. Trindade AJ, Kumta NA, Bhutani MS, Chandrasekhara V, Jirapinyo P, Krishnan K, Melson J, Pannala R, Parsi MA, Schulman AR, Trikudanathan G, Watson RR, Maple JT, Lichtenstein DR. Devices and techniques for endoscopic treatment of residual and fibrotic colorectal polyps (with videos). Gastrointest Endosc. 2020 Sep; 92(3):474-482. PMID: 32641215.
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    23. Melson JE, Imperiale TF, Itzkowitz SH, Llor X, Kochman ML, Grady WM, Schoen RE, Burke CA, Shaukat A, Rabeneck L, Ladabaum U, Bresalier R, Spiegel B, Yee J, Wang T, Lieberman D, Komanduri S, Muthusamy VR, Dey N. AGA White Paper: Roadmap for the Future of Colorectal Cancer Screening in the United States. Clin Gastroenterol Hepatol. 2020 11; 18(12):2667-2678.e2. PMID: 32634626.
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    24. Alsayid M, Melson J. Will magnet-assisted capsule endoscopy become a viable screening tool for Barrett's esophagus and esophageal varices? Gastrointest Endosc. 2020 04; 91(4):782-784. PMID: 32204813.
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    25. Dey N, Kochman ML, Komanduri S, Melson JE, Muthusamy VR. Report from the AGA Center for GI Innovation and Technology's Consensus Conference: Envisioning Next-Generation Paradigms in Colorectal Cancer Screening and Surveillance. Gastroenterology. 2020 02; 158(3):455-460. PMID: 31525354.
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    26. Tjaden J, Muller C, Wideroff G, Ma K, Satiya J, Sussman D, Yen E, Kupfer SS, Melson J. Metachronous Advanced Neoplasia on Surveillance Colonoscopy in Patients With Young- vs Older-onset of Colorectal Cancer. Clin Gastroenterol Hepatol. 2021 09; 19(9):1967-1969. PMID: 31351134.
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    27. Goodman AJ, Melson J, Aslanian HR, Bhutani MS, Krishnan K, Lichtenstein DR, Navaneethan U, Pannala R, Parsi MA, Schulman AR, Sethi A, Sullivan SA, Thosani N, Trikudanathan G, Trindade AJ, Watson RR, Maple JT. Endoscopic simulators. Gastrointest Endosc. 2019 07; 90(1):1-12. PMID: 31122746.
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    28. Trindade AJ, Navaneethan U, Aslanian HR, Bhutani MS, Krishnan K, Lichtenstein DR, Melson J, Pannala R, Parsi MA, Schulman AR, Sethi A, Trikudanathan G, Watson RR, Maple JT. Advances in the diagnosis and surveillance of Barrett's esophagus (with videos). Gastrointest Endosc. 2019 09; 90(3):325-334. PMID: 31113535.
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    29. Vutien P, Shah R, Ma K, Saleem N, Melson J. Utilization of Census Tract-Based Neighborhood Poverty Rates to Predict Non-adherence to Screening Colonoscopy. Dig Dis Sci. 2019 09; 64(9):2505-2513. PMID: 30874988.
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    30. Vleugels JLA, Hassan C, Senore C, Cassoni P, Baron JA, Rex DK, Ponugoti PL, Pellise M, Parejo S, Bessa X, Arnau-Collell C, Kaminski MF, Bugajski M, Wieszczy P, Kuipers EJ, Melson J, Ma KH, Holman R, Dekker E, Pohl H. Diminutive Polyps With Advanced Histologic Features Do Not Increase Risk for Metachronous Advanced Colon Neoplasia. Gastroenterology. 2019 02; 156(3):623-634.e3. PMID: 30395813.
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    31. Ma K, Melson J. Postcolonoscopy colorectal cancer rates: monitoring and reducing the worst-case scenario. Gastrointest Endosc. 2018 10; 88(4):712-714. PMID: 30217244.
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    32. Muller C, Lee SM, Barge W, Siddique SM, Berera S, Wideroff G, Tondon R, Chang J, Peterson M, Stoll J, Katona BW, Sussman DA, Melson J, Kupfer SS. Low Referral Rate for Genetic Testing in Racially and Ethnically Diverse Patients Despite Universal Colorectal Cancer Screening. Clin Gastroenterol Hepatol. 2018 12; 16(12):1911-1918.e2. PMID: 30130624.
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    33. Barge W, Kumar D, Giusto D, Kramer J, Behara R, Jakate S, Bishehsari F, Losurdo J, Lee S, Singh S, Melson J. Alternative approaches to polyp extraction in colonoscopy: a?proof of principle study. Gastrointest Endosc. 2018 09; 88(3):536-541. PMID: 29885336.
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    34. Trindade AJ, Lichtenstein DR, Aslanian HR, Bhutani MS, Goodman A, Melson J, Navaneethan U, Pannala R, Parsi MA, Sethi A, Sullivan S, Thosani N, Trikudanathan G, Watson RR, Maple JT. Devices and methods to improve colonoscopy completion?(with videos). Gastrointest Endosc. 2018 Mar; 87(3):625-634. PMID: 29454445.
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    35. Ma K, Melson J. Managing the patient with colorectal adenomas found at an?early age. Gastrointest Endosc. 2018 03; 87(3):674-676. PMID: 29454447.
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    36. Tjaden JM, Hause JA, Berger D, Duveneck SK, Jakate SM, Orkin BA, Hubbard EL, Melson JE. Adenoma detection rate metrics in colorectal cancer surveillance colonoscopy. Surg Endosc. 2018 07; 32(7):3108-3113. PMID: 29340817.
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    37. Hamoudah T, Ma K, Esteban M, Hayat W, Berger D, Mahon B, Jakate S, Melson J. Patients with small and diminutive proximal hyperplastic polyps have higher rates of synchronous advanced neoplasia compared with patients without serrated lesions. Gastrointest Endosc. 2018 Jun; 87(6):1518-1526. PMID: 29337039.
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    38. Jiang AC, Buckingham L, Barbanera W, Korang AY, Bishehsari F, Melson J. Erratum to: LINE-1 is preferentially hypomethylated within adenomatous polyps in the presence of synchronous colorectal cancer. Clin Epigenetics. 2017; 9:76. PMID: 28770016.
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    39. Trikudanathan G, Pannala R, Bhutani MS, Melson J, Navaneethan U, Parsi MA, Thosani N, Trindade AJ, Watson RR, Maple JT. EUS-guided portal vein interventions. Gastrointest Endosc. 2017 05; 85(5):883-888. PMID: 28320514.
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    40. Jiang AC, Buckingham L, Barbanera W, Korang AY, Bishesari F, Melson J. LINE-1 is preferentially hypomethylated within adenomatous polyps in the presence of synchronous colorectal cancer. Clin Epigenetics. 2017; 9:25. PMID: 28293326.
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    41. Greenspan M, Melson J. Seeking the Cecum: Assessing Metrics in Fellow Procedural Training. Dig Dis Sci. 2016 11; 61(11):3095-3096. PMID: 27619391.
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    42. Melson J, Berger D, Greenspan M, Bayoumi M, Jakate S. Maintaining low non-neoplastic polypectomy rates in high-quality screening colonoscopy. Gastrointest Endosc. 2017 Mar; 85(3):581-587. PMID: 27597424.
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    43. Desai V, Sussman DA, Greenspan M, Dayanand S, Ollington K, Patel S, Li H, Melson J. Most Premature Surveillance Colonoscopy Is Not Attributable to Bowel Preparation or New Clinical Indications. Dig Dis Sci. 2016 09; 61(9):2496-504. PMID: 27142669.
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    44. Melson J, Ma K, Arshad S, Greenspan M, Kaminsky T, Melvani V, Bishehsari F, Mahon B, Jakate S. Presence of small sessile serrated polyps increases rate of?advanced neoplasia upon surveillance compared with isolated?low-risk tubular adenomas. Gastrointest Endosc. 2016 Aug; 84(2):307-14. PMID: 26855297.
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    45. Shobar RM, Velineni S, Keshavarzian A, Swanson G, DeMeo MT, Melson JE, Losurdo J, Engen PA, Sun Y, Koenig L, Mutlu EA. The Effects of Bowel Preparation on Microbiota-Related Metrics Differ in Health and in Inflammatory Bowel Disease and for the Mucosal and Luminal Microbiota Compartments. Clin Transl Gastroenterol. 2016 Feb 11; 7:e143. PMID: 26866392.
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    46. Chen H, Liu H, Zou H, Chen R, Dou Y, Sheng S, Dai S, Ai J, Melson J, Kittles RA, Pirooznia M, Liptay MJ, Borgia JA, Deng Y. Evaluation of Plasma miR-21 and miR-152 as Diagnostic Biomarkers for Common Types of Human Cancers. J Cancer. 2016; 7(5):490-9. PMID: 26958084.
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    47. Greenspan M, Chehl N, Shawron K, Barnes L, Li H, Avery E, Sims S, Losurdo J, Mobarhan S, Melson J. Patient Non-adherence and Cancellations Are Higher for Screening Colonoscopy Compared with Surveillance Colonoscopy. Dig Dis Sci. 2015 Oct; 60(10):2930-6. PMID: 25902746.
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    48. Ma K, Nayak S, Li H, Evans K, Francescatti A, Brand MI, Orkin B, Hill M, Cameron J, Mobarhan S, Favuzza J, Melson J. Radiographic staging practices of newly diagnosed colorectal cancer vary according to medical specialty. Gastrointest Endosc. 2015 Sep; 82(3):497-502. PMID: 25910667.
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    49. Xicola RM, Gagnon M, Clark JR, Carroll T, Gao W, Fernandez C, Mijic D, Rawson JB, Janoski A, Pusatcioglu CK, Rajaram P, Gluskin AB, Regan M, Chaudhry V, Abcarian H, Blumetti J, Cintron J, Melson J, Xie H, Guzman G, Emmadi R, Alagiozian-Angelova V, Kupfer SS, Braunschweig C, Ellis NA, Llor X. Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study. Clin Cancer Res. 2014 Sep 15; 20(18):4962-70. PMID: 25013126.
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    50. Melson J, Desai V, Greenspan M, Yau S, Abdalla M, Dhanekula R, Mobarhan S, Shapiro D, Losurdo J, Jakate S. Negative surveillance endoscopy occurs frequently in patients with short-segment non-dysplastic Barrett's esophagus. Dis Esophagus. 2015 Oct; 28(7):660-5. PMID: 24943293.
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    51. Melson J, Li Y, Cassinotti E, Melnikov A, Boni L, Ai J, Greenspan M, Mobarhan S, Levenson V, Deng Y. Commonality and differences of methylation signatures in the plasma of patients with pancreatic cancer and colorectal cancer. Int J Cancer. 2014 Jun 01; 134(11):2656-62. PMID: 24288256.
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    52. Greenspan M, Rajan KB, Baig A, Beck T, Mobarhan S, Melson J. Advanced adenoma detection rate is independent of nonadvanced adenoma detection rate. Am J Gastroenterol. 2013 Aug; 108(8):1286-92. PMID: 23711625.
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    53. Khan MW, Keshavarzian A, Gounaris E, Melson JE, Cheon EC, Blatner NR, Chen ZE, Tsai FN, Lee G, Ryu H, Barrett TA, Bentrem DJ, Beckhove P, Khazaie K. PI3K/AKT signaling is essential for communication between tissue-infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer. Clin Cancer Res. 2013 May 01; 19(9):2342-54. PMID: 23487439.
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    54. Eichenseer PJ, Dhanekula R, Jakate S, Mobarhan S, Melson JE. Endoscopic mis-sizing of polyps changes colorectal cancer surveillance recommendations. Dis Colon Rectum. 2013 Mar; 56(3):315-21. PMID: 23392145.
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    55. Abdalla M, Dhanekula R, Greenspan M, Mobarhan S, Patil A, Jakate S, Giusto D, Silva R, Li H, Melson J. Dysplasia detection rate of confirmatory EGD in nondysplastic Barrett's esophagus. Dis Esophagus. 2014 Aug; 27(6):505-10. PMID: 23020509.
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    56. Cassinotti E, Melson J, Liggett T, Melnikov A, Yi Q, Replogle C, Mobarhan S, Boni L, Segato S, Levenson V. DNA methylation patterns in blood of patients with colorectal cancer and adenomatous colorectal polyps. Int J Cancer. 2012 Sep 01; 131(5):1153-7. PMID: 22020530.
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    57. Melson JE, Giusto D, Kwasny M, Eichenseer P, Jakate S, Keshavarzian A. Histopathology predictors of medically refractory ulcerative colitis. Dis Colon Rectum. 2010 Sep; 53(9):1280-6. PMID: 20706071.
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    58. Melson J, Jakate S, Fung H, Arai S, Keshavarzian A. Crypt loss is a marker of clinical severity of acute gastrointestinal graft-versus-host disease. Am J Hematol. 2007 Oct; 82(10):881-6. PMID: 17570511.
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    59. Quander CR, Morris MC, Melson J, Bienias JL, Evans DA. Prevalence of and factors associated with fecal incontinence in a large community study of older individuals. Am J Gastroenterol. 2005 Apr; 100(4):905-9. PMID: 15784039.
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