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Lei Duan

Concepts (286)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
85
3.340
Why?
Drug Resistance, Neoplasm
9
2024
68
3.270
Why?
Proto-Oncogene Proteins c-akt
8
2022
57
2.540
Why?
Imidazoles
7
2019
62
2.460
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
236
2.450
Why?
Piperazines
7
2019
82
2.430
Why?
Receptors, Estrogen
6
2022
62
2.370
Why?
Autophagy
8
2022
30
2.180
Why?
Antineoplastic Agents
9
2024
199
2.150
Why?
Breast Neoplasms
9
2022
401
1.800
Why?
Cell Line, Tumor
19
2024
248
1.760
Why?
Tamoxifen
4
2022
30
1.680
Why?
Lung Neoplasms
4
2023
543
1.670
Why?
Cisplatin
5
2022
60
1.360
Why?
Apoptosis
9
2019
198
1.170
Why?
Triple Negative Breast Neoplasms
3
2024
16
1.150
Why?
Gene Expression Regulation, Neoplastic
3
2024
114
1.020
Why?
Carboxypeptidases
3
2022
8
0.980
Why?
Neoplasms
2
2018
223
0.970
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
9
0.970
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.870
Why?
Glycolysis
3
2018
12
0.770
Why?
Retinoblastoma-Like Protein p130
1
2022
3
0.740
Why?
Signal Transduction
8
2022
402
0.740
Why?
Humans
37
2024
23572
0.730
Why?
Fatty Acids
1
2021
32
0.720
Why?
Neoplasm Recurrence, Local
1
2022
203
0.720
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.670
Why?
Phosphatidylinositol 3-Kinases
2
2021
44
0.610
Why?
Insulin Receptor Substrate Proteins
2
2020
15
0.600
Why?
ErbB Receptors
3
2010
54
0.600
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.590
Why?
Ketoglutaric Acids
1
2018
3
0.590
Why?
Sp1 Transcription Factor
1
2018
5
0.590
Why?
Proto-Oncogene Proteins c-cbl
5
2010
12
0.580
Why?
Ubiquitin-Protein Ligases
4
2007
26
0.540
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
34
0.540
Why?
Cell Lineage
1
2015
25
0.480
Why?
Protein Kinase Inhibitors
2
2017
57
0.450
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
26
0.440
Why?
Mice
12
2022
1249
0.440
Why?
Serine Endopeptidases
1
2014
14
0.440
Why?
Sirolimus
1
2014
20
0.440
Why?
Nitric Oxide
1
2014
73
0.430
Why?
Protein Kinases
1
2014
11
0.430
Why?
Enzyme Activation
6
2014
111
0.420
Why?
Proto-Oncogene Proteins
2
2004
33
0.420
Why?
Animals
16
2022
3311
0.410
Why?
MCF-7 Cells
3
2021
15
0.410
Why?
cdc42 GTP-Binding Protein
2
2010
7
0.400
Why?
rac1 GTP-Binding Protein
2
2010
14
0.400
Why?
Mammary Glands, Human
2
2009
7
0.400
Why?
rhoA GTP-Binding Protein
2
2009
9
0.390
Why?
Receptors, Glycine
2
2009
2
0.390
Why?
Paclitaxel
2
2022
49
0.380
Why?
RNA, Small Interfering
3
2019
76
0.370
Why?
Epithelial Cells
2
2010
71
0.350
Why?
Cytotoxins
1
2010
1
0.350
Why?
Adherens Junctions
1
2010
3
0.340
Why?
Neoplasm Proteins
1
2010
52
0.340
Why?
Cell Movement
1
2010
77
0.330
Why?
Cell Proliferation
1
2010
165
0.320
Why?
Morphogenesis
1
2009
8
0.320
Why?
Methylation
2
2019
10
0.310
Why?
Osteosarcoma
3
2018
40
0.310
Why?
Histones
2
2019
28
0.310
Why?
Cell Survival
4
2019
100
0.310
Why?
Caffeine
1
2009
53
0.300
Why?
Ubiquitin
5
2007
29
0.300
Why?
Cell Cycle Checkpoints
2
2022
7
0.290
Why?
Kidney
1
2009
144
0.290
Why?
Female
11
2024
13266
0.280
Why?
Bone Neoplasms
3
2018
127
0.280
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
9
0.270
Why?
Antineoplastic Agents, Hormonal
2
2021
19
0.260
Why?
Checkpoint Kinase 1
2
2019
7
0.260
Why?
Phosphorylation
6
2016
131
0.260
Why?
RNA Interference
2
2019
36
0.260
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.260
Why?
Cell Line
6
2013
250
0.260
Why?
Mycobacterium tuberculosis
2
2005
17
0.250
Why?
Gene Knockdown Techniques
2
2018
41
0.250
Why?
Mitochondria
2
2005
55
0.250
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
10
0.230
Why?
Nitrogen
1
2004
4
0.220
Why?
Oxygen
2
2015
58
0.220
Why?
Soil
1
2004
6
0.220
Why?
Receptors, Antigen
1
2004
1
0.220
Why?
Biomarkers, Tumor
2
2024
201
0.220
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.220
Why?
Trastuzumab
2
2022
26
0.220
Why?
Interleukin-6
1
2024
70
0.210
Why?
Histone Deacetylase 1
1
2023
3
0.210
Why?
Retinoblastoma Protein
1
2023
11
0.210
Why?
Benzamides
1
2023
13
0.210
Why?
Lysosomes
1
2003
20
0.200
Why?
Histone Demethylases
1
2022
3
0.200
Why?
Lysine
1
2022
14
0.200
Why?
Mitochondrial Swelling
1
2002
1
0.200
Why?
Cadherins
1
2022
30
0.200
Why?
Estrogen Receptor alpha
1
2022
15
0.200
Why?
Antigens, CD
1
2022
49
0.200
Why?
CD27 Ligand
1
2022
2
0.200
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.200
Why?
Nanoparticles
1
2022
10
0.190
Why?
Antineoplastic Agents, Immunological
1
2022
15
0.190
Why?
Aurora Kinase B
1
2022
3
0.190
Why?
Aurora Kinase A
1
2022
4
0.190
Why?
Macrophages
1
2002
91
0.190
Why?
Glioblastoma
1
2022
13
0.180
Why?
Oxidation-Reduction
1
2021
62
0.180
Why?
Brain Neoplasms
1
2022
91
0.170
Why?
Receptor, ErbB-2
3
2022
52
0.160
Why?
Receptor, IGF Type 1
2
2017
21
0.160
Why?
Autophagy-Related Proteins
1
2019
4
0.160
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.150
Why?
A549 Cells
1
2018
11
0.150
Why?
Pentose Phosphate Pathway
1
2018
3
0.150
Why?
Mutation
4
2010
330
0.140
Why?
Adenosine
1
2018
8
0.140
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
18
0.140
Why?
Heterocyclic Compounds, 3-Ring
2
2017
14
0.140
Why?
Cell Transformation, Neoplastic
2
2009
32
0.140
Why?
Receptors, Somatomedin
1
2017
5
0.140
Why?
Phospholipase C gamma
2
2007
6
0.140
Why?
Epidermal Growth Factor
2
2010
26
0.140
Why?
Loss of Heterozygosity
1
2016
6
0.120
Why?
DNA Mismatch Repair
1
2016
10
0.120
Why?
Biological Assay
1
2016
7
0.120
Why?
Protein-Tyrosine Kinases
2
2007
17
0.120
Why?
Macrolides
1
2015
6
0.120
Why?
Caspase 8
1
2015
10
0.120
Why?
Superoxides
1
2015
23
0.120
Why?
Chloroquine
1
2015
7
0.120
Why?
Microscopy, Electron, Transmission
1
2015
22
0.120
Why?
Cellular Senescence
1
2015
15
0.120
Why?
Microscopy, Electron
1
2015
61
0.120
Why?
Microscopy, Confocal
1
2015
81
0.120
Why?
Flow Cytometry
1
2015
102
0.120
Why?
DNA Methylation
1
2016
129
0.110
Why?
Phagosomes
1
2014
2
0.110
Why?
Microtubule-Associated Proteins
1
2014
15
0.110
Why?
Nitric Oxide Synthase Type III
1
2014
11
0.110
Why?
Protein Processing, Post-Translational
1
2014
33
0.110
Why?
DNA Primers
1
2014
49
0.110
Why?
Colorectal Neoplasms
1
2016
109
0.110
Why?
MAP Kinase Signaling System
1
2014
35
0.110
Why?
Base Sequence
1
2014
102
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
64
0.110
Why?
Models, Biological
1
2016
305
0.110
Why?
Gene Expression Regulation
2
2007
233
0.110
Why?
DNA Damage
1
2014
26
0.110
Why?
Transfection
3
2020
117
0.100
Why?
Membrane Potentials
2
2005
167
0.100
Why?
Cell Adhesion
2
2010
31
0.100
Why?
Aniline Compounds
1
2013
29
0.100
Why?
Triazoles
1
2013
29
0.100
Why?
Dose-Response Relationship, Drug
2
2011
322
0.090
Why?
Triterpenes
1
2011
1
0.090
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
6
0.090
Why?
Ubiquitination
1
2010
15
0.090
Why?
Protein Transport
1
2010
29
0.090
Why?
Actins
1
2010
35
0.080
Why?
Cytoskeleton
1
2010
33
0.080
Why?
Amino Acid Sequence
1
2010
148
0.080
Why?
Molecular Sequence Data
1
2010
186
0.080
Why?
Cell Line, Transformed
1
2009
13
0.080
Why?
Mice, Nude
3
2020
25
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
240
0.080
Why?
Precancerous Conditions
1
2009
25
0.070
Why?
Urodela
1
2008
1
0.070
Why?
Retinal Ganglion Cells
1
2008
2
0.070
Why?
Glycine
1
2008
7
0.070
Why?
Synaptic Transmission
1
2008
20
0.070
Why?
Neural Inhibition
1
2008
8
0.070
Why?
RNA, Messenger
2
2013
285
0.070
Why?
Xenograft Model Antitumor Assays
2
2022
21
0.070
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
4
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
9
0.070
Why?
Neovascularization, Physiologic
1
2007
23
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.060
Why?
Necrosis
2
2005
24
0.060
Why?
Cells, Cultured
2
2008
472
0.060
Why?
Macrophages, Alveolar
1
2005
3
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
38
0.060
Why?
Immune Tolerance
1
2004
12
0.060
Why?
China
1
2004
45
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
16
0.060
Why?
Hydrogen-Ion Concentration
1
2004
127
0.050
Why?
Oncogene Proteins
1
2003
6
0.050
Why?
Mice, Knockout
1
2004
283
0.050
Why?
CHO Cells
1
2003
11
0.050
Why?
Cricetinae
1
2003
35
0.050
Why?
Embryo, Mammalian
1
2003
24
0.050
Why?
Endosomes
1
2003
8
0.050
Why?
Endocytosis
1
2003
16
0.050
Why?
Temperature
1
2003
58
0.050
Why?
Fibroblasts
1
2003
50
0.050
Why?
Blotting, Western
1
2003
132
0.050
Why?
Down-Regulation
1
2003
91
0.050
Why?
Ionophores
1
2002
2
0.050
Why?
Calcimycin
1
2002
4
0.050
Why?
Ruthenium Red
1
2002
7
0.050
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Cytochrome c Group
1
2002
4
0.050
Why?
Blood Bactericidal Activity
1
2002
4
0.050
Why?
Intracellular Membranes
1
2002
20
0.050
Why?
Caspases
1
2002
22
0.050
Why?
Calcium-Binding Proteins
1
2002
22
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Caspase 3
1
2022
17
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Permeability
1
2002
95
0.050
Why?
Gene Expression
1
2003
179
0.050
Why?
Molecular Docking Simulation
1
2022
2
0.050
Why?
Calcium Channels
1
2002
106
0.050
Why?
Genistein
1
2022
5
0.050
Why?
Protein Binding
3
2007
114
0.040
Why?
Structure-Activity Relationship
2
2013
34
0.040
Why?
Luciferases
2
2013
25
0.040
Why?
Disease Models, Animal
1
2020
528
0.040
Why?
Pyrazines
1
2017
12
0.030
Why?
Reproductive History
1
2017
1
0.030
Why?
Receptors, Progesterone
1
2017
26
0.030
Why?
Receptor Cross-Talk
1
2016
7
0.030
Why?
Odds Ratio
1
2017
230
0.030
Why?
Population Surveillance
1
2017
107
0.030
Why?
Tyrosine
2
2007
22
0.030
Why?
Protein Structure, Tertiary
2
2007
60
0.030
Why?
Case-Control Studies
1
2017
505
0.030
Why?
Computer Simulation
1
2016
176
0.030
Why?
Risk Assessment
1
2017
556
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
11
0.030
Why?
Biological Availability
1
2013
16
0.030
Why?
Genes, Reporter
1
2013
22
0.030
Why?
Administration, Oral
1
2013
99
0.020
Why?
Transcription, Genetic
1
2013
97
0.020
Why?
Rats, Sprague-Dawley
1
2013
315
0.020
Why?
Male
2
2020
12777
0.020
Why?
Rats
1
2013
624
0.020
Why?
Young Adult
1
2017
1747
0.020
Why?
Risk Factors
1
2017
1997
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
5
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
4
0.020
Why?
Tumor Burden
1
2011
24
0.020
Why?
Drug Evaluation, Preclinical
1
2011
29
0.020
Why?
Quinazolines
1
2011
17
0.020
Why?
Mice, SCID
1
2011
40
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
84
0.020
Why?
Antibodies, Monoclonal
1
2011
167
0.020
Why?
rho-Associated Kinases
1
2009
4
0.020
Why?
Telomerase
1
2009
10
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
48
0.020
Why?
Protein Kinase C
1
2009
47
0.020
Why?
Retina
1
2008
8
0.020
Why?
Ligands
1
2007
37
0.020
Why?
Laminin
1
2007
5
0.020
Why?
Binding Sites
1
2007
68
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Drug Combinations
1
2007
32
0.020
Why?
Mutagenesis, Site-Directed
1
2007
17
0.020
Why?
Gene Silencing
1
2007
23
0.020
Why?
Tumor Cells, Cultured
1
2007
128
0.020
Why?
Collagen
1
2007
81
0.020
Why?
Enzyme Inhibitors
1
2007
115
0.020
Why?
Proteoglycans
1
2007
120
0.020
Why?
Wound Healing
1
2007
123
0.020
Why?
Receptors, Purinergic P2
1
2005
1
0.010
Why?
Cytochromes c
1
2005
11
0.010
Why?
Adenosine Triphosphate
1
2005
21
0.010
Why?
Cyclosporine
1
2005
12
0.010
Why?
Adult
1
2017
7178
0.010
Why?
Molecular Conformation
1
2004
10
0.010
Why?
Middle Aged
1
2017
8155
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
8
0.010
Why?
Precipitin Tests
1
2003
10
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
24
0.010
Why?
Immunoblotting
1
2003
54
0.010
Why?
Plasmids
1
2003
42
0.010
Why?
Models, Genetic
1
2003
31
0.010
Why?
Mice, Transgenic
1
2003
176
0.010
Why?
Time Factors
1
2003
1295
0.010
Why?
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