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Lei Duan

Concepts (283)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
91
3.630
Why?
Proto-Oncogene Proteins c-akt
8
2022
55
2.780
Why?
Imidazoles
7
2019
72
2.670
Why?
Drug Resistance, Neoplasm
8
2022
77
2.670
Why?
Piperazines
7
2019
93
2.630
Why?
Receptors, Estrogen
6
2022
68
2.580
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
321
2.560
Why?
Autophagy
8
2022
30
2.380
Why?
Antineoplastic Agents
8
2019
252
2.060
Why?
Breast Neoplasms
9
2022
352
2.020
Why?
Tamoxifen
4
2022
30
1.840
Why?
Lung Neoplasms
4
2023
636
1.740
Why?
Cell Line, Tumor
18
2022
273
1.680
Why?
Cisplatin
5
2022
92
1.480
Why?
Apoptosis
9
2019
259
1.240
Why?
Carboxypeptidases
3
2022
6
1.070
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
6
1.060
Why?
Neoplasms
2
2018
257
1.020
Why?
Gene Expression Regulation, Neoplastic
2
2022
107
0.890
Why?
Glycolysis
3
2018
21
0.840
Why?
Retinoblastoma-Like Protein p130
1
2022
2
0.810
Why?
Fatty Acids
1
2021
39
0.790
Why?
Signal Transduction
8
2022
491
0.790
Why?
Neoplasm Recurrence, Local
1
2022
200
0.780
Why?
Proto-Oncogene Proteins c-vav
3
2010
3
0.740
Why?
Phosphatidylinositol 3-Kinases
2
2021
47
0.660
Why?
Insulin Receptor Substrate Proteins
2
2020
14
0.660
Why?
Humans
36
2023
29851
0.650
Why?
Ketoglutaric Acids
1
2018
2
0.650
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.650
Why?
ErbB Receptors
3
2010
73
0.640
Why?
Sp1 Transcription Factor
1
2018
8
0.640
Why?
Proto-Oncogene Proteins c-cbl
5
2010
14
0.640
Why?
Ubiquitin-Protein Ligases
4
2007
41
0.590
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
30
0.590
Why?
Cell Lineage
1
2015
31
0.520
Why?
Protein Kinase Inhibitors
2
2017
55
0.480
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
28
0.480
Why?
Serine Endopeptidases
1
2014
16
0.480
Why?
Sirolimus
1
2014
17
0.480
Why?
Protein Kinases
1
2014
15
0.470
Why?
Nitric Oxide
1
2014
103
0.460
Why?
Enzyme Activation
6
2014
112
0.460
Why?
Proto-Oncogene Proteins
2
2004
32
0.460
Why?
Mice
12
2022
1628
0.460
Why?
MCF-7 Cells
3
2021
17
0.450
Why?
cdc42 GTP-Binding Protein
2
2010
4
0.440
Why?
rac1 GTP-Binding Protein
2
2010
12
0.440
Why?
rhoA GTP-Binding Protein
2
2009
7
0.430
Why?
Mammary Glands, Human
2
2009
6
0.430
Why?
Receptors, Glycine
2
2009
2
0.420
Why?
Paclitaxel
2
2022
74
0.410
Why?
RNA, Small Interfering
3
2019
65
0.410
Why?
Animals
16
2022
4639
0.400
Why?
Cytotoxins
1
2010
5
0.380
Why?
Adherens Junctions
1
2010
4
0.380
Why?
Epithelial Cells
2
2010
88
0.370
Why?
Neoplasm Proteins
1
2010
53
0.370
Why?
Cell Movement
1
2010
105
0.360
Why?
Cell Proliferation
1
2010
206
0.350
Why?
Morphogenesis
1
2009
7
0.350
Why?
Methylation
2
2019
7
0.340
Why?
Osteosarcoma
3
2018
33
0.340
Why?
Histones
2
2019
28
0.330
Why?
Caffeine
1
2009
64
0.330
Why?
Ubiquitin
5
2007
26
0.330
Why?
Cell Survival
4
2019
165
0.330
Why?
Triple Negative Breast Neoplasms
2
2020
14
0.330
Why?
Cell Cycle Checkpoints
2
2022
6
0.320
Why?
Bone Neoplasms
3
2018
106
0.310
Why?
Kidney
1
2009
176
0.300
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
10
0.300
Why?
Antineoplastic Agents, Hormonal
2
2021
18
0.290
Why?
Checkpoint Kinase 1
2
2019
5
0.290
Why?
RNA Interference
2
2019
34
0.280
Why?
Phosphorylation
6
2016
159
0.280
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.280
Why?
Mycobacterium tuberculosis
2
2005
19
0.280
Why?
Gene Knockdown Techniques
2
2018
42
0.280
Why?
Cell Line
6
2013
299
0.280
Why?
Mitochondria
2
2005
84
0.270
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
7
0.250
Why?
Nitrogen
1
2004
4
0.250
Why?
Soil
1
2004
6
0.250
Why?
Receptors, Antigen
1
2004
1
0.240
Why?
Oxygen
2
2015
86
0.240
Why?
Trastuzumab
2
2022
26
0.230
Why?
Histone Deacetylase 1
1
2023
2
0.230
Why?
Retinoblastoma Protein
1
2023
10
0.230
Why?
Benzamides
1
2023
18
0.230
Why?
Lysosomes
1
2003
24
0.220
Why?
Histone Demethylases
1
2022
2
0.220
Why?
Lysine
1
2022
13
0.220
Why?
Cadherins
1
2022
31
0.220
Why?
Mitochondrial Swelling
1
2002
1
0.220
Why?
Estrogen Receptor alpha
1
2022
15
0.220
Why?
CD27 Ligand
1
2022
2
0.210
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.210
Why?
Nanoparticles
1
2022
14
0.210
Why?
Antigens, CD
1
2022
102
0.210
Why?
Antineoplastic Agents, Immunological
1
2022
20
0.210
Why?
Aurora Kinase A
1
2022
2
0.200
Why?
Aurora Kinase B
1
2022
2
0.200
Why?
Female
10
2022
16430
0.200
Why?
Glioblastoma
1
2022
14
0.200
Why?
Macrophages
1
2002
128
0.200
Why?
Oxidation-Reduction
1
2021
71
0.200
Why?
Brain Neoplasms
1
2022
134
0.180
Why?
Receptor, ErbB-2
3
2022
46
0.180
Why?
Receptor, IGF Type 1
2
2017
19
0.170
Why?
Autophagy-Related Proteins
1
2019
2
0.170
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
3
0.170
Why?
A549 Cells
1
2018
9
0.160
Why?
Pentose Phosphate Pathway
1
2018
3
0.160
Why?
Adenosine
1
2018
12
0.160
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
30
0.160
Why?
Heterocyclic Compounds, 3-Ring
2
2017
15
0.150
Why?
Mutation
4
2010
399
0.150
Why?
Cell Transformation, Neoplastic
2
2009
36
0.150
Why?
Receptors, Somatomedin
1
2017
4
0.150
Why?
Phospholipase C gamma
2
2007
9
0.150
Why?
Epidermal Growth Factor
2
2010
32
0.150
Why?
Loss of Heterozygosity
1
2016
4
0.140
Why?
DNA Mismatch Repair
1
2016
6
0.140
Why?
Biological Assay
1
2016
9
0.130
Why?
Protein-Tyrosine Kinases
2
2007
21
0.130
Why?
Macrolides
1
2015
5
0.130
Why?
Caspase 8
1
2015
11
0.130
Why?
Superoxides
1
2015
26
0.130
Why?
Chloroquine
1
2015
12
0.130
Why?
Microscopy, Electron, Transmission
1
2015
29
0.130
Why?
Cellular Senescence
1
2015
18
0.130
Why?
Microscopy, Electron
1
2015
75
0.130
Why?
Microscopy, Confocal
1
2015
116
0.130
Why?
Flow Cytometry
1
2015
202
0.130
Why?
Colorectal Neoplasms
1
2016
82
0.130
Why?
DNA Methylation
1
2016
128
0.130
Why?
Phagosomes
1
2014
3
0.120
Why?
Microtubule-Associated Proteins
1
2014
21
0.120
Why?
Nitric Oxide Synthase Type III
1
2014
17
0.120
Why?
Protein Processing, Post-Translational
1
2014
36
0.120
Why?
DNA Primers
1
2014
54
0.120
Why?
MAP Kinase Signaling System
1
2014
38
0.120
Why?
Nitric Oxide Synthase Type II
1
2014
65
0.120
Why?
Base Sequence
1
2014
135
0.120
Why?
DNA Damage
1
2014
30
0.120
Why?
Models, Biological
1
2016
347
0.120
Why?
Transfection
3
2020
130
0.110
Why?
Gene Expression Regulation
2
2007
285
0.110
Why?
Cell Adhesion
2
2010
45
0.110
Why?
Membrane Potentials
2
2005
193
0.110
Why?
Aniline Compounds
1
2013
41
0.110
Why?
Triazoles
1
2013
33
0.110
Why?
Dose-Response Relationship, Drug
2
2011
456
0.100
Why?
Triterpenes
1
2011
2
0.100
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
8
0.090
Why?
Ubiquitination
1
2010
11
0.090
Why?
Protein Transport
1
2010
39
0.090
Why?
Actins
1
2010
45
0.090
Why?
Cytoskeleton
1
2010
51
0.090
Why?
Amino Acid Sequence
1
2010
196
0.090
Why?
Molecular Sequence Data
1
2010
248
0.090
Why?
Cell Line, Transformed
1
2009
17
0.090
Why?
Mice, Nude
3
2020
35
0.090
Why?
Precancerous Conditions
1
2009
22
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
329
0.080
Why?
Urodela
1
2008
1
0.080
Why?
Retinal Ganglion Cells
1
2008
3
0.080
Why?
Neural Inhibition
1
2008
10
0.080
Why?
Glycine
1
2008
12
0.080
Why?
Synaptic Transmission
1
2008
46
0.080
Why?
RNA, Messenger
2
2013
325
0.080
Why?
Xenograft Model Antitumor Assays
2
2022
25
0.080
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
4
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
7
0.070
Why?
Neovascularization, Physiologic
1
2007
21
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.070
Why?
Necrosis
2
2005
27
0.070
Why?
Cells, Cultured
2
2008
682
0.060
Why?
Macrophages, Alveolar
1
2005
4
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
66
0.060
Why?
Immune Tolerance
1
2004
23
0.060
Why?
China
1
2004
58
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
33
0.060
Why?
Hydrogen-Ion Concentration
1
2004
149
0.060
Why?
Oncogene Proteins
1
2003
7
0.060
Why?
CHO Cells
1
2003
11
0.060
Why?
Mice, Knockout
1
2004
309
0.060
Why?
Cricetinae
1
2003
37
0.060
Why?
Embryo, Mammalian
1
2003
30
0.060
Why?
Endosomes
1
2003
8
0.060
Why?
Endocytosis
1
2003
17
0.060
Why?
Temperature
1
2003
74
0.060
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Ionophores
1
2002
3
0.050
Why?
Calcimycin
1
2002
5
0.050
Why?
Ruthenium Red
1
2002
8
0.050
Why?
Blotting, Western
1
2003
175
0.050
Why?
Cytochrome c Group
1
2002
7
0.050
Why?
Blood Bactericidal Activity
1
2002
6
0.050
Why?
Fibroblasts
1
2003
93
0.050
Why?
Down-Regulation
1
2003
113
0.050
Why?
Caspases
1
2002
33
0.050
Why?
Intracellular Membranes
1
2002
33
0.050
Why?
Caspase 9
1
2022
12
0.050
Why?
Calcium-Binding Proteins
1
2002
24
0.050
Why?
Caspase 3
1
2022
30
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Permeability
1
2002
139
0.050
Why?
Gene Expression
1
2003
232
0.050
Why?
Molecular Docking Simulation
1
2022
1
0.050
Why?
Genistein
1
2022
3
0.050
Why?
Calcium Channels
1
2002
130
0.050
Why?
Protein Binding
3
2007
125
0.050
Why?
Structure-Activity Relationship
2
2013
43
0.040
Why?
Luciferases
2
2013
24
0.040
Why?
Pyrazines
1
2017
11
0.040
Why?
Disease Models, Animal
1
2020
744
0.040
Why?
Reproductive History
1
2017
1
0.040
Why?
Receptors, Progesterone
1
2017
32
0.040
Why?
Receptor Cross-Talk
1
2016
7
0.030
Why?
Population Surveillance
1
2017
118
0.030
Why?
Odds Ratio
1
2017
286
0.030
Why?
Tyrosine
2
2007
25
0.030
Why?
Protein Structure, Tertiary
2
2007
63
0.030
Why?
Biomarkers, Tumor
1
2017
198
0.030
Why?
Case-Control Studies
1
2017
643
0.030
Why?
Computer Simulation
1
2016
219
0.030
Why?
Risk Assessment
1
2017
685
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
13
0.030
Why?
Biological Availability
1
2013
26
0.030
Why?
Genes, Reporter
1
2013
29
0.030
Why?
Transcription, Genetic
1
2013
107
0.030
Why?
Administration, Oral
1
2013
144
0.030
Why?
Rats, Sprague-Dawley
1
2013
463
0.030
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
7
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
7
0.020
Why?
Tumor Burden
1
2011
30
0.020
Why?
Drug Evaluation, Preclinical
1
2011
34
0.020
Why?
Rats
1
2013
877
0.020
Why?
Mice, SCID
1
2011
57
0.020
Why?
Quinazolines
1
2011
24
0.020
Why?
Young Adult
1
2017
1969
0.020
Why?
Male
2
2020
15871
0.020
Why?
Risk Factors
1
2017
2467
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
119
0.020
Why?
Antibodies, Monoclonal
1
2011
270
0.020
Why?
rho-Associated Kinases
1
2009
6
0.020
Why?
Telomerase
1
2009
10
0.020
Why?
Protein Kinase C
1
2009
47
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
78
0.020
Why?
Retina
1
2008
12
0.020
Why?
Ligands
1
2007
58
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Binding Sites
1
2007
76
0.020
Why?
Laminin
1
2007
8
0.020
Why?
Mutagenesis, Site-Directed
1
2007
19
0.020
Why?
Gene Silencing
1
2007
23
0.020
Why?
Drug Combinations
1
2007
82
0.020
Why?
Tumor Cells, Cultured
1
2007
149
0.020
Why?
Collagen
1
2007
102
0.020
Why?
Enzyme Inhibitors
1
2007
147
0.020
Why?
Wound Healing
1
2007
168
0.020
Why?
Proteoglycans
1
2007
345
0.020
Why?
Receptors, Purinergic P2
1
2005
2
0.020
Why?
Cytochromes c
1
2005
15
0.020
Why?
Adenosine Triphosphate
1
2005
44
0.020
Why?
Cyclosporine
1
2005
16
0.020
Why?
Molecular Conformation
1
2004
15
0.020
Why?
Adult
1
2017
8748
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
13
0.010
Why?
Precipitin Tests
1
2003
12
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
35
0.010
Why?
Immunoblotting
1
2003
52
0.010
Why?
Plasmids
1
2003
44
0.010
Why?
Models, Genetic
1
2003
36
0.010
Why?
Middle Aged
1
2017
9963
0.010
Why?
Mice, Transgenic
1
2003
256
0.010
Why?
Time Factors
1
2003
1641
0.010
Why?
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