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Lei Duan

Concepts (286)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
92
3.440
Why?
Drug Resistance, Neoplasm
9
2024
69
3.370
Why?
Proto-Oncogene Proteins c-akt
8
2022
57
2.620
Why?
Imidazoles
7
2019
59
2.550
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
243
2.510
Why?
Piperazines
7
2019
85
2.500
Why?
Receptors, Estrogen
6
2022
65
2.440
Why?
Autophagy
8
2022
35
2.250
Why?
Antineoplastic Agents
9
2024
198
2.210
Why?
Breast Neoplasms
9
2022
409
1.840
Why?
Cell Line, Tumor
19
2024
256
1.810
Why?
Tamoxifen
4
2022
30
1.730
Why?
Lung Neoplasms
4
2023
552
1.700
Why?
Cisplatin
5
2022
58
1.410
Why?
Apoptosis
9
2019
213
1.200
Why?
Triple Negative Breast Neoplasms
3
2024
18
1.190
Why?
Gene Expression Regulation, Neoplastic
3
2024
116
1.050
Why?
Carboxypeptidases
3
2022
8
1.010
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
9
1.000
Why?
Neoplasms
2
2018
237
0.980
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.900
Why?
Glycolysis
3
2018
13
0.800
Why?
Retinoblastoma-Like Protein p130
1
2022
3
0.770
Why?
Signal Transduction
8
2022
443
0.750
Why?
Fatty Acids
1
2021
40
0.740
Why?
Neoplasm Recurrence, Local
1
2022
206
0.740
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.700
Why?
Humans
37
2024
27072
0.690
Why?
Phosphatidylinositol 3-Kinases
2
2021
44
0.630
Why?
Insulin Receptor Substrate Proteins
2
2020
17
0.620
Why?
ErbB Receptors
3
2010
54
0.620
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.610
Why?
Ketoglutaric Acids
1
2018
3
0.610
Why?
Sp1 Transcription Factor
1
2018
5
0.610
Why?
Proto-Oncogene Proteins c-cbl
5
2010
12
0.600
Why?
Ubiquitin-Protein Ligases
4
2007
24
0.560
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
34
0.550
Why?
Cell Lineage
1
2015
24
0.500
Why?
Protein Kinase Inhibitors
2
2017
53
0.460
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
28
0.460
Why?
Serine Endopeptidases
1
2014
15
0.450
Why?
Sirolimus
1
2014
19
0.450
Why?
Nitric Oxide
1
2014
79
0.440
Why?
Mice
12
2022
1395
0.440
Why?
Protein Kinases
1
2014
13
0.440
Why?
Enzyme Activation
6
2014
118
0.440
Why?
Proto-Oncogene Proteins
2
2004
35
0.430
Why?
MCF-7 Cells
3
2021
15
0.430
Why?
cdc42 GTP-Binding Protein
2
2010
7
0.420
Why?
rac1 GTP-Binding Protein
2
2010
14
0.420
Why?
Animals
16
2022
3642
0.410
Why?
Mammary Glands, Human
2
2009
7
0.410
Why?
rhoA GTP-Binding Protein
2
2009
9
0.410
Why?
Receptors, Glycine
2
2009
2
0.400
Why?
Paclitaxel
2
2022
50
0.400
Why?
RNA, Small Interfering
3
2019
81
0.390
Why?
Epithelial Cells
2
2010
77
0.360
Why?
Cytotoxins
1
2010
1
0.360
Why?
Adherens Junctions
1
2010
3
0.350
Why?
Neoplasm Proteins
1
2010
56
0.350
Why?
Cell Movement
1
2010
80
0.340
Why?
Cell Proliferation
1
2010
175
0.330
Why?
Morphogenesis
1
2009
8
0.330
Why?
Methylation
2
2019
11
0.320
Why?
Osteosarcoma
3
2018
40
0.320
Why?
Caffeine
1
2009
57
0.310
Why?
Histones
2
2019
32
0.310
Why?
Cell Survival
4
2019
121
0.310
Why?
Ubiquitin
5
2007
31
0.310
Why?
Cell Cycle Checkpoints
2
2022
7
0.300
Why?
Kidney
1
2009
153
0.300
Why?
Bone Neoplasms
3
2018
130
0.290
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
12
0.280
Why?
Antineoplastic Agents, Hormonal
2
2021
18
0.270
Why?
Checkpoint Kinase 1
2
2019
7
0.270
Why?
Female
11
2024
15212
0.270
Why?
Phosphorylation
6
2016
149
0.270
Why?
RNA Interference
2
2019
38
0.270
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.270
Why?
Mycobacterium tuberculosis
2
2005
17
0.260
Why?
Gene Knockdown Techniques
2
2018
45
0.260
Why?
Cell Line
6
2013
273
0.260
Why?
Mitochondria
2
2005
67
0.260
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
10
0.240
Why?
Nitrogen
1
2004
4
0.230
Why?
Soil
1
2004
6
0.230
Why?
Oxygen
2
2015
68
0.230
Why?
Receptors, Antigen
1
2004
1
0.230
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.230
Why?
Biomarkers, Tumor
2
2024
205
0.230
Why?
Trastuzumab
2
2022
26
0.220
Why?
Interleukin-6
1
2024
74
0.220
Why?
Histone Deacetylase 1
1
2023
3
0.220
Why?
Retinoblastoma Protein
1
2023
11
0.220
Why?
Benzamides
1
2023
15
0.220
Why?
Lysosomes
1
2003
26
0.210
Why?
Histone Demethylases
1
2022
3
0.210
Why?
Lysine
1
2022
14
0.210
Why?
Mitochondrial Swelling
1
2002
1
0.200
Why?
Cadherins
1
2022
34
0.200
Why?
Estrogen Receptor alpha
1
2022
16
0.200
Why?
CD27 Ligand
1
2022
2
0.200
Why?
Antigens, CD
1
2022
50
0.200
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.200
Why?
Nanoparticles
1
2022
11
0.200
Why?
Antineoplastic Agents, Immunological
1
2022
15
0.200
Why?
Aurora Kinase B
1
2022
3
0.190
Why?
Aurora Kinase A
1
2022
4
0.190
Why?
Macrophages
1
2002
102
0.190
Why?
Glioblastoma
1
2022
9
0.190
Why?
Oxidation-Reduction
1
2021
65
0.190
Why?
Brain Neoplasms
1
2022
86
0.180
Why?
Receptor, ErbB-2
3
2022
51
0.170
Why?
Receptor, IGF Type 1
2
2017
21
0.160
Why?
Autophagy-Related Proteins
1
2019
4
0.160
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.160
Why?
A549 Cells
1
2018
11
0.150
Why?
Pentose Phosphate Pathway
1
2018
3
0.150
Why?
Mutation
4
2010
348
0.150
Why?
Adenosine
1
2018
8
0.150
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
21
0.150
Why?
Heterocyclic Compounds, 3-Ring
2
2017
14
0.150
Why?
Cell Transformation, Neoplastic
2
2009
32
0.140
Why?
Receptors, Somatomedin
1
2017
5
0.140
Why?
Phospholipase C gamma
2
2007
8
0.140
Why?
Epidermal Growth Factor
2
2010
27
0.140
Why?
Loss of Heterozygosity
1
2016
6
0.130
Why?
DNA Mismatch Repair
1
2016
8
0.130
Why?
Biological Assay
1
2016
8
0.130
Why?
Protein-Tyrosine Kinases
2
2007
15
0.130
Why?
Macrolides
1
2015
6
0.120
Why?
Caspase 8
1
2015
10
0.120
Why?
Superoxides
1
2015
25
0.120
Why?
Chloroquine
1
2015
7
0.120
Why?
Microscopy, Electron, Transmission
1
2015
26
0.120
Why?
Cellular Senescence
1
2015
18
0.120
Why?
Microscopy, Electron
1
2015
65
0.120
Why?
Microscopy, Confocal
1
2015
88
0.120
Why?
Flow Cytometry
1
2015
107
0.120
Why?
Phagosomes
1
2014
3
0.120
Why?
Microtubule-Associated Proteins
1
2014
19
0.110
Why?
Nitric Oxide Synthase Type III
1
2014
11
0.110
Why?
DNA Methylation
1
2016
161
0.110
Why?
Protein Processing, Post-Translational
1
2014
39
0.110
Why?
DNA Primers
1
2014
52
0.110
Why?
Colorectal Neoplasms
1
2016
110
0.110
Why?
MAP Kinase Signaling System
1
2014
36
0.110
Why?
Base Sequence
1
2014
109
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
67
0.110
Why?
Models, Biological
1
2016
322
0.110
Why?
DNA Damage
1
2014
29
0.110
Why?
Gene Expression Regulation
2
2007
271
0.110
Why?
Transfection
3
2020
121
0.110
Why?
Membrane Potentials
2
2005
180
0.110
Why?
Cell Adhesion
2
2010
31
0.110
Why?
Aniline Compounds
1
2013
35
0.110
Why?
Triazoles
1
2013
29
0.100
Why?
Dose-Response Relationship, Drug
2
2011
333
0.100
Why?
Triterpenes
1
2011
1
0.090
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
7
0.090
Why?
Ubiquitination
1
2010
15
0.090
Why?
Protein Transport
1
2010
32
0.090
Why?
Actins
1
2010
34
0.090
Why?
Cytoskeleton
1
2010
34
0.090
Why?
Amino Acid Sequence
1
2010
156
0.090
Why?
Molecular Sequence Data
1
2010
195
0.090
Why?
Cell Line, Transformed
1
2009
15
0.080
Why?
Mice, Nude
3
2020
25
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
245
0.080
Why?
Precancerous Conditions
1
2009
25
0.080
Why?
Urodela
1
2008
1
0.070
Why?
Retinal Ganglion Cells
1
2008
2
0.070
Why?
Glycine
1
2008
7
0.070
Why?
Neural Inhibition
1
2008
8
0.070
Why?
Synaptic Transmission
1
2008
25
0.070
Why?
RNA, Messenger
2
2013
310
0.070
Why?
Xenograft Model Antitumor Assays
2
2022
24
0.070
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
5
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
9
0.070
Why?
Neovascularization, Physiologic
1
2007
25
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.070
Why?
Necrosis
2
2005
26
0.070
Why?
Cells, Cultured
2
2008
520
0.060
Why?
Macrophages, Alveolar
1
2005
5
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
40
0.060
Why?
Immune Tolerance
1
2004
14
0.060
Why?
China
1
2004
46
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
16
0.060
Why?
Hydrogen-Ion Concentration
1
2004
143
0.060
Why?
Oncogene Proteins
1
2003
6
0.050
Why?
CHO Cells
1
2003
12
0.050
Why?
Cricetinae
1
2003
36
0.050
Why?
Embryo, Mammalian
1
2003
25
0.050
Why?
Endosomes
1
2003
8
0.050
Why?
Mice, Knockout
1
2004
301
0.050
Why?
Endocytosis
1
2003
17
0.050
Why?
Temperature
1
2003
63
0.050
Why?
Fibroblasts
1
2003
58
0.050
Why?
Blotting, Western
1
2003
147
0.050
Why?
Ionophores
1
2002
2
0.050
Why?
Calcimycin
1
2002
4
0.050
Why?
Ruthenium Red
1
2002
7
0.050
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Cytochrome c Group
1
2002
4
0.050
Why?
Blood Bactericidal Activity
1
2002
4
0.050
Why?
Down-Regulation
1
2003
99
0.050
Why?
Intracellular Membranes
1
2002
21
0.050
Why?
Caspases
1
2002
26
0.050
Why?
Calcium-Binding Proteins
1
2002
22
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Caspase 3
1
2022
20
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Permeability
1
2002
97
0.050
Why?
Gene Expression
1
2003
199
0.050
Why?
Molecular Docking Simulation
1
2022
2
0.050
Why?
Genistein
1
2022
4
0.050
Why?
Calcium Channels
1
2002
112
0.050
Why?
Protein Binding
3
2007
126
0.040
Why?
Structure-Activity Relationship
2
2013
37
0.040
Why?
Luciferases
2
2013
24
0.040
Why?
Disease Models, Animal
1
2020
599
0.040
Why?
Pyrazines
1
2017
11
0.040
Why?
Reproductive History
1
2017
1
0.030
Why?
Receptors, Progesterone
1
2017
26
0.030
Why?
Receptor Cross-Talk
1
2016
7
0.030
Why?
Population Surveillance
1
2017
115
0.030
Why?
Odds Ratio
1
2017
270
0.030
Why?
Tyrosine
2
2007
23
0.030
Why?
Protein Structure, Tertiary
2
2007
60
0.030
Why?
Case-Control Studies
1
2017
587
0.030
Why?
Computer Simulation
1
2016
195
0.030
Why?
Risk Assessment
1
2017
624
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
11
0.030
Why?
Biological Availability
1
2013
17
0.030
Why?
Genes, Reporter
1
2013
22
0.030
Why?
Administration, Oral
1
2013
108
0.030
Why?
Transcription, Genetic
1
2013
107
0.030
Why?
Rats, Sprague-Dawley
1
2013
332
0.020
Why?
Rats
1
2013
664
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
7
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
5
0.020
Why?
Quinazolines
1
2011
16
0.020
Why?
Drug Evaluation, Preclinical
1
2011
30
0.020
Why?
Tumor Burden
1
2011
27
0.020
Why?
Mice, SCID
1
2011
42
0.020
Why?
Male
2
2020
14772
0.020
Why?
Young Adult
1
2017
1994
0.020
Why?
Risk Factors
1
2017
2302
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
85
0.020
Why?
Antibodies, Monoclonal
1
2011
177
0.020
Why?
rho-Associated Kinases
1
2009
4
0.020
Why?
Telomerase
1
2009
10
0.020
Why?
Protein Kinase C
1
2009
48
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
64
0.020
Why?
Retina
1
2008
7
0.020
Why?
Ligands
1
2007
39
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Binding Sites
1
2007
73
0.020
Why?
Laminin
1
2007
8
0.020
Why?
Drug Combinations
1
2007
33
0.020
Why?
Mutagenesis, Site-Directed
1
2007
19
0.020
Why?
Gene Silencing
1
2007
23
0.020
Why?
Tumor Cells, Cultured
1
2007
129
0.020
Why?
Collagen
1
2007
86
0.020
Why?
Enzyme Inhibitors
1
2007
114
0.020
Why?
Proteoglycans
1
2007
140
0.020
Why?
Wound Healing
1
2007
153
0.020
Why?
Receptors, Purinergic P2
1
2005
1
0.020
Why?
Cytochromes c
1
2005
11
0.020
Why?
Adenosine Triphosphate
1
2005
22
0.020
Why?
Cyclosporine
1
2005
12
0.010
Why?
Molecular Conformation
1
2004
10
0.010
Why?
Adult
1
2017
7831
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
10
0.010
Why?
Precipitin Tests
1
2003
12
0.010
Why?
Middle Aged
1
2017
8923
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
27
0.010
Why?
Immunoblotting
1
2003
54
0.010
Why?
Plasmids
1
2003
45
0.010
Why?
Models, Genetic
1
2003
41
0.010
Why?
Mice, Transgenic
1
2003
219
0.010
Why?
Time Factors
1
2003
1433
0.010
Why?
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