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Lei Duan

Concepts (286)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
80
3.540
Why?
Drug Resistance, Neoplasm
9
2024
61
3.460
Why?
Proto-Oncogene Proteins c-akt
8
2022
44
2.710
Why?
Imidazoles
7
2019
55
2.610
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
216
2.610
Why?
Piperazines
7
2019
76
2.580
Why?
Receptors, Estrogen
6
2022
57
2.510
Why?
Autophagy
8
2022
29
2.310
Why?
Antineoplastic Agents
9
2024
176
2.280
Why?
Breast Neoplasms
9
2022
353
1.930
Why?
Cell Line, Tumor
19
2024
230
1.860
Why?
Tamoxifen
4
2022
24
1.780
Why?
Lung Neoplasms
4
2023
505
1.770
Why?
Cisplatin
5
2022
47
1.440
Why?
Apoptosis
9
2019
193
1.240
Why?
Triple Negative Breast Neoplasms
3
2024
16
1.220
Why?
Gene Expression Regulation, Neoplastic
3
2024
95
1.090
Why?
Carboxypeptidases
3
2022
6
1.040
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
6
1.030
Why?
Neoplasms
2
2018
219
1.010
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.920
Why?
Glycolysis
3
2018
10
0.820
Why?
Signal Transduction
8
2022
388
0.790
Why?
Retinoblastoma-Like Protein p130
1
2022
2
0.790
Why?
Fatty Acids
1
2021
36
0.760
Why?
Neoplasm Recurrence, Local
1
2022
184
0.760
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.720
Why?
Humans
37
2024
25967
0.710
Why?
Phosphatidylinositol 3-Kinases
2
2021
40
0.650
Why?
Insulin Receptor Substrate Proteins
2
2020
14
0.640
Why?
ErbB Receptors
3
2010
51
0.630
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
2
0.630
Why?
Ketoglutaric Acids
1
2018
2
0.630
Why?
Sp1 Transcription Factor
1
2018
5
0.620
Why?
Proto-Oncogene Proteins c-cbl
5
2010
12
0.620
Why?
Ubiquitin-Protein Ligases
4
2007
24
0.570
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
30
0.570
Why?
Cell Lineage
1
2015
22
0.510
Why?
Protein Kinase Inhibitors
2
2017
45
0.470
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
26
0.470
Why?
Serine Endopeptidases
1
2014
13
0.460
Why?
Sirolimus
1
2014
19
0.460
Why?
Mice
12
2022
1280
0.460
Why?
Nitric Oxide
1
2014
75
0.460
Why?
Protein Kinases
1
2014
12
0.450
Why?
Enzyme Activation
6
2014
103
0.450
Why?
Proto-Oncogene Proteins
2
2004
29
0.450
Why?
MCF-7 Cells
3
2021
13
0.440
Why?
cdc42 GTP-Binding Protein
2
2010
6
0.430
Why?
Animals
16
2022
3386
0.430
Why?
rac1 GTP-Binding Protein
2
2010
12
0.430
Why?
rhoA GTP-Binding Protein
2
2009
6
0.420
Why?
Mammary Glands, Human
2
2009
7
0.420
Why?
Receptors, Glycine
2
2009
2
0.410
Why?
Paclitaxel
2
2022
42
0.410
Why?
RNA, Small Interfering
3
2019
68
0.400
Why?
Cytotoxins
1
2010
2
0.370
Why?
Epithelial Cells
2
2010
75
0.370
Why?
Adherens Junctions
1
2010
4
0.360
Why?
Neoplasm Proteins
1
2010
51
0.360
Why?
Cell Movement
1
2010
77
0.350
Why?
Cell Proliferation
1
2010
161
0.350
Why?
Morphogenesis
1
2009
8
0.340
Why?
Methylation
2
2019
6
0.330
Why?
Osteosarcoma
3
2018
35
0.330
Why?
Caffeine
1
2009
52
0.320
Why?
Histones
2
2019
24
0.320
Why?
Cell Survival
4
2019
111
0.320
Why?
Ubiquitin
5
2007
24
0.320
Why?
Cell Cycle Checkpoints
2
2022
5
0.310
Why?
Kidney
1
2009
155
0.300
Why?
Bone Neoplasms
3
2018
118
0.300
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
10
0.290
Why?
Antineoplastic Agents, Hormonal
2
2021
14
0.280
Why?
Female
11
2024
14351
0.280
Why?
Checkpoint Kinase 1
2
2019
5
0.280
Why?
RNA Interference
2
2019
29
0.280
Why?
Phosphorylation
6
2016
133
0.280
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.270
Why?
Cell Line
6
2013
244
0.270
Why?
Mycobacterium tuberculosis
2
2005
16
0.270
Why?
Gene Knockdown Techniques
2
2018
42
0.270
Why?
Mitochondria
2
2005
57
0.270
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
7
0.250
Why?
Nitrogen
1
2004
4
0.240
Why?
Soil
1
2004
6
0.240
Why?
Oxygen
2
2015
72
0.240
Why?
Receptors, Antigen
1
2004
1
0.240
Why?
Biomarkers, Tumor
2
2024
179
0.230
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.230
Why?
Trastuzumab
2
2022
25
0.230
Why?
Interleukin-6
1
2024
72
0.230
Why?
Histone Deacetylase 1
1
2023
2
0.220
Why?
Retinoblastoma Protein
1
2023
10
0.220
Why?
Benzamides
1
2023
15
0.220
Why?
Lysosomes
1
2003
25
0.210
Why?
Histone Demethylases
1
2022
2
0.210
Why?
Lysine
1
2022
12
0.210
Why?
Cadherins
1
2022
34
0.210
Why?
Mitochondrial Swelling
1
2002
1
0.210
Why?
Estrogen Receptor alpha
1
2022
15
0.210
Why?
CD27 Ligand
1
2022
2
0.210
Why?
Antigens, CD
1
2022
51
0.210
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.210
Why?
Nanoparticles
1
2022
10
0.210
Why?
Antineoplastic Agents, Immunological
1
2022
15
0.200
Why?
Aurora Kinase A
1
2022
2
0.200
Why?
Aurora Kinase B
1
2022
2
0.200
Why?
Glioblastoma
1
2022
7
0.200
Why?
Macrophages
1
2002
104
0.200
Why?
Oxidation-Reduction
1
2021
62
0.190
Why?
Brain Neoplasms
1
2022
73
0.190
Why?
Receptor, ErbB-2
3
2022
47
0.170
Why?
Receptor, IGF Type 1
2
2017
17
0.170
Why?
Autophagy-Related Proteins
1
2019
2
0.160
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
3
0.160
Why?
A549 Cells
1
2018
10
0.160
Why?
Pentose Phosphate Pathway
1
2018
2
0.160
Why?
Mutation
4
2010
311
0.150
Why?
Adenosine
1
2018
7
0.150
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
20
0.150
Why?
Heterocyclic Compounds, 3-Ring
2
2017
13
0.150
Why?
Cell Transformation, Neoplastic
2
2009
31
0.150
Why?
Receptors, Somatomedin
1
2017
4
0.140
Why?
Phospholipase C gamma
2
2007
8
0.140
Why?
Epidermal Growth Factor
2
2010
28
0.140
Why?
Loss of Heterozygosity
1
2016
5
0.130
Why?
DNA Mismatch Repair
1
2016
5
0.130
Why?
Biological Assay
1
2016
6
0.130
Why?
Protein-Tyrosine Kinases
2
2007
15
0.130
Why?
Macrolides
1
2015
4
0.130
Why?
Caspase 8
1
2015
8
0.130
Why?
Superoxides
1
2015
23
0.130
Why?
Chloroquine
1
2015
6
0.130
Why?
Microscopy, Electron, Transmission
1
2015
25
0.130
Why?
Cellular Senescence
1
2015
14
0.130
Why?
Microscopy, Electron
1
2015
65
0.130
Why?
Microscopy, Confocal
1
2015
85
0.120
Why?
Flow Cytometry
1
2015
109
0.120
Why?
Colorectal Neoplasms
1
2016
75
0.120
Why?
DNA Methylation
1
2016
119
0.120
Why?
Phagosomes
1
2014
3
0.120
Why?
Microtubule-Associated Proteins
1
2014
19
0.120
Why?
Nitric Oxide Synthase Type III
1
2014
9
0.120
Why?
Protein Processing, Post-Translational
1
2014
33
0.120
Why?
DNA Primers
1
2014
45
0.120
Why?
Base Sequence
1
2014
89
0.120
Why?
MAP Kinase Signaling System
1
2014
35
0.120
Why?
Nitric Oxide Synthase Type II
1
2014
67
0.110
Why?
Models, Biological
1
2016
304
0.110
Why?
Gene Expression Regulation
2
2007
236
0.110
Why?
DNA Damage
1
2014
24
0.110
Why?
Transfection
3
2020
104
0.110
Why?
Membrane Potentials
2
2005
167
0.110
Why?
Cell Adhesion
2
2010
32
0.110
Why?
Aniline Compounds
1
2013
35
0.110
Why?
Triazoles
1
2013
27
0.110
Why?
Dose-Response Relationship, Drug
2
2011
315
0.100
Why?
Triterpenes
1
2011
1
0.090
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
7
0.090
Why?
Ubiquitination
1
2010
10
0.090
Why?
Protein Transport
1
2010
30
0.090
Why?
Actins
1
2010
35
0.090
Why?
Cytoskeleton
1
2010
38
0.090
Why?
Amino Acid Sequence
1
2010
132
0.090
Why?
Molecular Sequence Data
1
2010
162
0.090
Why?
Cell Line, Transformed
1
2009
15
0.080
Why?
Mice, Nude
3
2020
23
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
224
0.080
Why?
Precancerous Conditions
1
2009
20
0.080
Why?
Urodela
1
2008
1
0.080
Why?
Retinal Ganglion Cells
1
2008
2
0.080
Why?
Synaptic Transmission
1
2008
24
0.080
Why?
Neural Inhibition
1
2008
8
0.080
Why?
Glycine
1
2008
12
0.080
Why?
RNA, Messenger
2
2013
264
0.080
Why?
Xenograft Model Antitumor Assays
2
2022
21
0.070
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
3
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
7
0.070
Why?
Neovascularization, Physiologic
1
2007
17
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.070
Why?
Necrosis
2
2005
26
0.070
Why?
Cells, Cultured
2
2008
475
0.060
Why?
Macrophages, Alveolar
1
2005
4
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
38
0.060
Why?
Immune Tolerance
1
2004
11
0.060
Why?
China
1
2004
50
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
16
0.060
Why?
Hydrogen-Ion Concentration
1
2004
129
0.060
Why?
Oncogene Proteins
1
2003
5
0.050
Why?
Mice, Knockout
1
2004
265
0.050
Why?
CHO Cells
1
2003
10
0.050
Why?
Embryo, Mammalian
1
2003
22
0.050
Why?
Cricetinae
1
2003
35
0.050
Why?
Endosomes
1
2003
7
0.050
Why?
Endocytosis
1
2003
16
0.050
Why?
Temperature
1
2003
57
0.050
Why?
Fibroblasts
1
2003
56
0.050
Why?
Blotting, Western
1
2003
133
0.050
Why?
Down-Regulation
1
2003
92
0.050
Why?
Caspase Inhibitors
1
2002
4
0.050
Why?
Ionophores
1
2002
2
0.050
Why?
Calcimycin
1
2002
4
0.050
Why?
Ruthenium Red
1
2002
7
0.050
Why?
Cytochrome c Group
1
2002
4
0.050
Why?
Blood Bactericidal Activity
1
2002
5
0.050
Why?
Intracellular Membranes
1
2002
20
0.050
Why?
Caspases
1
2002
26
0.050
Why?
Calcium-Binding Proteins
1
2002
23
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Caspase 3
1
2022
19
0.050
Why?
Ceramides
1
2022
13
0.050
Why?
Permeability
1
2002
116
0.050
Why?
Gene Expression
1
2003
179
0.050
Why?
Molecular Docking Simulation
1
2022
1
0.050
Why?
Genistein
1
2022
3
0.050
Why?
Calcium Channels
1
2002
107
0.050
Why?
Protein Binding
3
2007
113
0.050
Why?
Structure-Activity Relationship
2
2013
34
0.040
Why?
Luciferases
2
2013
22
0.040
Why?
Disease Models, Animal
1
2020
568
0.040
Why?
Pyrazines
1
2017
10
0.040
Why?
Reproductive History
1
2017
1
0.040
Why?
Receptors, Progesterone
1
2017
23
0.030
Why?
Receptor Cross-Talk
1
2016
6
0.030
Why?
Population Surveillance
1
2017
101
0.030
Why?
Odds Ratio
1
2017
259
0.030
Why?
Tyrosine
2
2007
24
0.030
Why?
Protein Structure, Tertiary
2
2007
51
0.030
Why?
Case-Control Studies
1
2017
546
0.030
Why?
Computer Simulation
1
2016
193
0.030
Why?
Risk Assessment
1
2017
621
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
10
0.030
Why?
Biological Availability
1
2013
18
0.030
Why?
Genes, Reporter
1
2013
22
0.030
Why?
Transcription, Genetic
1
2013
91
0.030
Why?
Administration, Oral
1
2013
100
0.030
Why?
Rats, Sprague-Dawley
1
2013
317
0.030
Why?
Rats
1
2013
598
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Male
2
2020
13984
0.020
Why?
Inhibitory Concentration 50
1
2011
7
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
5
0.020
Why?
Tumor Burden
1
2011
19
0.020
Why?
Quinazolines
1
2011
13
0.020
Why?
Drug Evaluation, Preclinical
1
2011
27
0.020
Why?
Mice, SCID
1
2011
38
0.020
Why?
Young Adult
1
2017
1848
0.020
Why?
Risk Factors
1
2017
2240
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
87
0.020
Why?
Antibodies, Monoclonal
1
2011
192
0.020
Why?
rho-Associated Kinases
1
2009
5
0.020
Why?
Telomerase
1
2009
9
0.020
Why?
Protein Kinase C
1
2009
47
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
61
0.020
Why?
Retina
1
2008
7
0.020
Why?
Ligands
1
2007
39
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Binding Sites
1
2007
65
0.020
Why?
Laminin
1
2007
8
0.020
Why?
Drug Combinations
1
2007
33
0.020
Why?
Mutagenesis, Site-Directed
1
2007
14
0.020
Why?
Gene Silencing
1
2007
19
0.020
Why?
Tumor Cells, Cultured
1
2007
116
0.020
Why?
Collagen
1
2007
80
0.020
Why?
Enzyme Inhibitors
1
2007
114
0.020
Why?
Proteoglycans
1
2007
128
0.020
Why?
Wound Healing
1
2007
146
0.020
Why?
Receptors, Purinergic P2
1
2005
1
0.020
Why?
Cytochromes c
1
2005
11
0.020
Why?
Adenosine Triphosphate
1
2005
21
0.020
Why?
Cyclosporine
1
2005
11
0.020
Why?
Adult
1
2017
7351
0.010
Why?
Molecular Conformation
1
2004
10
0.010
Why?
Middle Aged
1
2017
8508
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
10
0.010
Why?
Precipitin Tests
1
2003
10
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
24
0.010
Why?
Plasmids
1
2003
35
0.010
Why?
Immunoblotting
1
2003
55
0.010
Why?
Models, Genetic
1
2003
26
0.010
Why?
Mice, Transgenic
1
2003
200
0.010
Why?
Time Factors
1
2003
1361
0.010
Why?
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