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Lei Duan

Concepts (284)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.


Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Tumor Suppressor Protein p53
9
2023
85
3.320
Why?
Drug Resistance, Neoplasm
9
2024
67
3.260
Why?
Proto-Oncogene Proteins c-akt
8
2022
56
2.530
Why?
Carcinoma, Non-Small-Cell Lung
4
2023
229
2.460
Why?
Imidazoles
7
2019
62
2.450
Why?
Piperazines
7
2019
81
2.420
Why?
Receptors, Estrogen
6
2022
62
2.360
Why?
Antineoplastic Agents
9
2024
196
2.150
Why?
Autophagy
7
2022
28
2.050
Why?
Breast Neoplasms
9
2022
375
1.820
Why?
Cell Line, Tumor
19
2024
242
1.750
Why?
Lung Neoplasms
4
2023
529
1.680
Why?
Tamoxifen
4
2022
30
1.670
Why?
Cisplatin
5
2022
60
1.350
Why?
Apoptosis
9
2019
195
1.170
Why?
Triple Negative Breast Neoplasms
3
2024
16
1.140
Why?
Gene Expression Regulation, Neoplastic
3
2024
111
1.010
Why?
Carboxypeptidases
3
2022
8
0.980
Why?
Neoplasms
2
2018
216
0.970
Why?
Jumonji Domain-Containing Histone Demethylases
3
2022
9
0.960
Why?
Myeloid Cell Leukemia Sequence 1 Protein
1
2024
4
0.870
Why?
Glycolysis
3
2018
11
0.770
Why?
Retinoblastoma-Like Protein p130
1
2022
3
0.740
Why?
Signal Transduction
8
2022
393
0.740
Why?
Humans
36
2024
22592
0.730
Why?
Neoplasm Recurrence, Local
1
2022
195
0.720
Why?
Fatty Acids
1
2021
31
0.720
Why?
Proto-Oncogene Proteins c-vav
3
2010
5
0.670
Why?
Phosphatidylinositol 3-Kinases
2
2021
43
0.610
Why?
Insulin Receptor Substrate Proteins
2
2020
14
0.600
Why?
ErbB Receptors
3
2010
53
0.600
Why?
Ketoglutarate Dehydrogenase Complex
1
2018
3
0.590
Why?
Ketoglutaric Acids
1
2018
3
0.590
Why?
Sp1 Transcription Factor
1
2018
5
0.580
Why?
Proto-Oncogene Proteins c-cbl
5
2010
11
0.580
Why?
Ubiquitin-Protein Ligases
4
2007
26
0.540
Why?
Proto-Oncogene Proteins c-mdm2
4
2019
34
0.530
Why?
Cell Lineage
1
2015
25
0.480
Why?
Protein Kinase Inhibitors
2
2017
55
0.440
Why?
Mice
12
2022
1224
0.440
Why?
Extracellular Signal-Regulated MAP Kinases
1
2014
26
0.440
Why?
Serine Endopeptidases
1
2014
14
0.440
Why?
Sirolimus
1
2014
20
0.430
Why?
Nitric Oxide
1
2014
71
0.430
Why?
Protein Kinases
1
2014
11
0.430
Why?
Enzyme Activation
6
2014
110
0.420
Why?
Proto-Oncogene Proteins
2
2004
33
0.420
Why?
MCF-7 Cells
3
2021
15
0.410
Why?
cdc42 GTP-Binding Protein
2
2010
7
0.400
Why?
rac1 GTP-Binding Protein
2
2010
13
0.400
Why?
Animals
15
2022
3238
0.400
Why?
Mammary Glands, Human
2
2009
7
0.390
Why?
rhoA GTP-Binding Protein
2
2009
9
0.390
Why?
Receptors, Glycine
2
2009
2
0.380
Why?
Paclitaxel
2
2022
49
0.380
Why?
RNA, Small Interfering
3
2019
76
0.370
Why?
Epithelial Cells
2
2010
70
0.350
Why?
Cytotoxins
1
2010
1
0.340
Why?
Adherens Junctions
1
2010
3
0.340
Why?
Neoplasm Proteins
1
2010
50
0.340
Why?
Cell Movement
1
2010
77
0.330
Why?
Cell Proliferation
1
2010
164
0.320
Why?
Morphogenesis
1
2009
8
0.320
Why?
Methylation
2
2019
10
0.310
Why?
Osteosarcoma
3
2018
35
0.310
Why?
Histones
2
2019
28
0.300
Why?
Cell Survival
4
2019
98
0.300
Why?
Caffeine
1
2009
53
0.300
Why?
Ubiquitin
5
2007
29
0.300
Why?
Cell Cycle Checkpoints
2
2022
7
0.290
Why?
Kidney
1
2009
139
0.290
Why?
Female
11
2024
12734
0.290
Why?
Bone Neoplasms
3
2018
117
0.280
Why?
Mechanistic Target of Rapamycin Complex 1
2
2018
9
0.270
Why?
Antineoplastic Agents, Hormonal
2
2021
18
0.260
Why?
Checkpoint Kinase 1
2
2019
7
0.260
Why?
Phosphorylation
6
2016
131
0.260
Why?
RNA Interference
2
2019
36
0.260
Why?
Retroviridae Proteins, Oncogenic
2
2003
2
0.260
Why?
Cell Line
6
2013
250
0.250
Why?
Mycobacterium tuberculosis
2
2005
17
0.250
Why?
Gene Knockdown Techniques
2
2018
41
0.250
Why?
Mitochondria
2
2005
54
0.250
Why?
Cyclin-Dependent Kinase Inhibitor p27
2
2016
10
0.230
Why?
Oxygen
2
2015
53
0.220
Why?
Nitrogen
1
2004
4
0.220
Why?
Soil
1
2004
6
0.220
Why?
Receptors, Antigen
1
2004
1
0.220
Why?
Biomarkers, Tumor
2
2024
198
0.220
Why?
Proto-Oncogene Protein c-ets-1
1
2024
2
0.220
Why?
Trastuzumab
2
2022
26
0.210
Why?
Interleukin-6
1
2024
68
0.210
Why?
Histone Deacetylase 1
1
2023
3
0.210
Why?
Benzamides
1
2023
12
0.210
Why?
Retinoblastoma Protein
1
2023
11
0.210
Why?
Lysosomes
1
2003
20
0.200
Why?
Histone Demethylases
1
2022
3
0.200
Why?
Lysine
1
2022
14
0.200
Why?
Mitochondrial Swelling
1
2002
1
0.200
Why?
Cadherins
1
2022
30
0.200
Why?
Estrogen Receptor alpha
1
2022
15
0.200
Why?
Antigens, CD
1
2022
49
0.200
Why?
CD27 Ligand
1
2022
2
0.200
Why?
MAP Kinase Kinase Kinases
1
2022
3
0.190
Why?
Nanoparticles
1
2022
10
0.190
Why?
Antineoplastic Agents, Immunological
1
2022
15
0.190
Why?
Aurora Kinase B
1
2022
3
0.190
Why?
Aurora Kinase A
1
2022
4
0.190
Why?
Macrophages
1
2002
88
0.190
Why?
Glioblastoma
1
2022
8
0.180
Why?
Oxidation-Reduction
1
2021
61
0.180
Why?
Brain Neoplasms
1
2022
70
0.170
Why?
Receptor, ErbB-2
3
2022
52
0.160
Why?
Receptor, IGF Type 1
2
2017
21
0.160
Why?
Autophagy-Related Proteins
1
2019
4
0.150
Why?
Ataxia Telangiectasia Mutated Proteins
1
2019
5
0.150
Why?
A549 Cells
1
2018
10
0.150
Why?
Pentose Phosphate Pathway
1
2018
3
0.150
Why?
Mutation
4
2010
327
0.140
Why?
Adenosine
1
2018
8
0.140
Why?
Proto-Oncogene Proteins c-bcl-2
1
2018
18
0.140
Why?
Heterocyclic Compounds, 3-Ring
2
2017
13
0.140
Why?
Cell Transformation, Neoplastic
2
2009
31
0.140
Why?
Receptors, Somatomedin
1
2017
5
0.140
Why?
Phospholipase C gamma
2
2007
6
0.130
Why?
Epidermal Growth Factor
2
2010
26
0.130
Why?
Loss of Heterozygosity
1
2016
6
0.120
Why?
DNA Mismatch Repair
1
2016
10
0.120
Why?
Protein-Tyrosine Kinases
2
2007
17
0.120
Why?
Macrolides
1
2015
6
0.120
Why?
Caspase 8
1
2015
10
0.120
Why?
Superoxides
1
2015
23
0.120
Why?
Microscopy, Electron, Transmission
1
2015
21
0.120
Why?
Chloroquine
1
2015
7
0.120
Why?
Cellular Senescence
1
2015
15
0.120
Why?
Microscopy, Electron
1
2015
60
0.120
Why?
Microscopy, Confocal
1
2015
80
0.120
Why?
Flow Cytometry
1
2015
102
0.120
Why?
DNA Methylation
1
2016
127
0.110
Why?
Phagosomes
1
2014
2
0.110
Why?
Microtubule-Associated Proteins
1
2014
14
0.110
Why?
Nitric Oxide Synthase Type III
1
2014
9
0.110
Why?
Protein Processing, Post-Translational
1
2014
33
0.110
Why?
DNA Primers
1
2014
50
0.110
Why?
Colorectal Neoplasms
1
2016
105
0.110
Why?
MAP Kinase Signaling System
1
2014
35
0.110
Why?
Base Sequence
1
2014
100
0.110
Why?
Nitric Oxide Synthase Type II
1
2014
62
0.110
Why?
Models, Biological
1
2016
300
0.110
Why?
Gene Expression Regulation
2
2007
229
0.110
Why?
DNA Damage
1
2014
25
0.110
Why?
Transfection
3
2020
119
0.100
Why?
Membrane Potentials
2
2005
169
0.100
Why?
Cell Adhesion
2
2010
30
0.100
Why?
Aniline Compounds
1
2013
29
0.100
Why?
Triazoles
1
2013
29
0.100
Why?
Dose-Response Relationship, Drug
2
2011
314
0.090
Why?
Triterpenes
1
2011
1
0.090
Why?
Estrogen Antagonists
1
2010
3
0.090
Why?
src-Family Kinases
3
2007
6
0.090
Why?
Ubiquitination
1
2010
14
0.080
Why?
Protein Transport
1
2010
29
0.080
Why?
Actins
1
2010
35
0.080
Why?
Cytoskeleton
1
2010
33
0.080
Why?
Amino Acid Sequence
1
2010
148
0.080
Why?
Molecular Sequence Data
1
2010
186
0.080
Why?
Cell Line, Transformed
1
2009
13
0.080
Why?
Mice, Nude
3
2020
25
0.080
Why?
Antineoplastic Combined Chemotherapy Protocols
1
2011
240
0.080
Why?
Precancerous Conditions
1
2009
25
0.070
Why?
Urodela
1
2008
1
0.070
Why?
Retinal Ganglion Cells
1
2008
2
0.070
Why?
Glycine
1
2008
7
0.070
Why?
Synaptic Transmission
1
2008
20
0.070
Why?
Neural Inhibition
1
2008
8
0.070
Why?
RNA, Messenger
2
2013
280
0.070
Why?
Xenograft Model Antitumor Assays
2
2022
21
0.070
Why?
Receptor, Platelet-Derived Growth Factor beta
1
2007
4
0.070
Why?
Vascular Endothelial Growth Factor Receptor-2
1
2007
9
0.070
Why?
Neovascularization, Physiologic
1
2007
22
0.070
Why?
Oncogene Protein v-cbl
2
2003
2
0.060
Why?
Necrosis
2
2005
24
0.060
Why?
Cells, Cultured
2
2008
467
0.060
Why?
Macrophages, Alveolar
1
2005
3
0.060
Why?
Plant Development
1
2004
3
0.060
Why?
Drug Synergism
2
2017
38
0.060
Why?
Immune Tolerance
1
2004
12
0.060
Why?
China
1
2004
45
0.060
Why?
Receptors, Antigen, T-Cell
1
2004
16
0.050
Why?
Hydrogen-Ion Concentration
1
2004
123
0.050
Why?
Oncogene Proteins
1
2003
6
0.050
Why?
Mice, Knockout
1
2004
277
0.050
Why?
CHO Cells
1
2003
11
0.050
Why?
Cricetinae
1
2003
34
0.050
Why?
Embryo, Mammalian
1
2003
23
0.050
Why?
Endosomes
1
2003
8
0.050
Why?
Endocytosis
1
2003
16
0.050
Why?
Temperature
1
2003
56
0.050
Why?
Fibroblasts
1
2003
50
0.050
Why?
Blotting, Western
1
2003
130
0.050
Why?
Down-Regulation
1
2003
88
0.050
Why?
Ionophores
1
2002
2
0.050
Why?
Calcimycin
1
2002
4
0.050
Why?
Ruthenium Red
1
2002
7
0.050
Why?
Caspase Inhibitors
1
2002
5
0.050
Why?
Cytochrome c Group
1
2002
4
0.050
Why?
Blood Bactericidal Activity
1
2002
4
0.050
Why?
Intracellular Membranes
1
2002
21
0.050
Why?
Caspases
1
2002
22
0.050
Why?
Calcium-Binding Proteins
1
2002
21
0.050
Why?
Caspase 9
1
2022
8
0.050
Why?
Caspase 3
1
2022
17
0.050
Why?
Ceramides
1
2022
14
0.050
Why?
Gene Expression
1
2003
174
0.050
Why?
Permeability
1
2002
94
0.050
Why?
Molecular Docking Simulation
1
2022
2
0.050
Why?
Genistein
1
2022
5
0.050
Why?
Calcium Channels
1
2002
110
0.050
Why?
Protein Binding
3
2007
114
0.040
Why?
Structure-Activity Relationship
2
2013
34
0.040
Why?
Luciferases
2
2013
25
0.040
Why?
Disease Models, Animal
1
2020
512
0.040
Why?
Pyrazines
1
2017
12
0.030
Why?
Reproductive History
1
2017
1
0.030
Why?
Receptors, Progesterone
1
2017
26
0.030
Why?
Receptor Cross-Talk
1
2016
7
0.030
Why?
Odds Ratio
1
2017
217
0.030
Why?
Population Surveillance
1
2017
100
0.030
Why?
Case-Control Studies
1
2017
477
0.030
Why?
Tyrosine
2
2007
22
0.030
Why?
Protein Structure, Tertiary
2
2007
60
0.030
Why?
Risk Assessment
1
2017
537
0.030
Why?
Drug Screening Assays, Antitumor
1
2013
11
0.030
Why?
Biological Availability
1
2013
16
0.030
Why?
Genes, Reporter
1
2013
22
0.030
Why?
Administration, Oral
1
2013
98
0.020
Why?
Transcription, Genetic
1
2013
96
0.020
Why?
Rats, Sprague-Dawley
1
2013
312
0.020
Why?
Male
2
2020
12260
0.020
Why?
Young Adult
1
2017
1607
0.020
Why?
Rats
1
2013
625
0.020
Why?
Risk Factors
1
2017
1955
0.020
Why?
Pentacyclic Triterpenes
1
2011
1
0.020
Why?
Inhibitory Concentration 50
1
2011
5
0.020
Why?
HSP90 Heat-Shock Proteins
1
2011
4
0.020
Why?
Tumor Burden
1
2011
23
0.020
Why?
Drug Evaluation, Preclinical
1
2011
27
0.020
Why?
Quinazolines
1
2011
17
0.020
Why?
Mice, SCID
1
2011
40
0.020
Why?
Antibodies, Monoclonal, Humanized
1
2011
83
0.020
Why?
Antibodies, Monoclonal
1
2011
163
0.020
Why?
rho-Associated Kinases
1
2009
4
0.020
Why?
Telomerase
1
2009
8
0.020
Why?
Adaptor Proteins, Signal Transducing
1
2009
45
0.020
Why?
Protein Kinase C
1
2009
47
0.020
Why?
Retina
1
2008
8
0.020
Why?
Ligands
1
2007
39
0.020
Why?
Laminin
1
2007
5
0.020
Why?
Binding Sites
1
2007
67
0.020
Why?
Cell Growth Processes
1
2007
6
0.020
Why?
Drug Combinations
1
2007
31
0.020
Why?
Mutagenesis, Site-Directed
1
2007
17
0.020
Why?
Tumor Cells, Cultured
1
2007
124
0.020
Why?
Gene Silencing
1
2007
23
0.020
Why?
Collagen
1
2007
78
0.020
Why?
Enzyme Inhibitors
1
2007
113
0.020
Why?
Proteoglycans
1
2007
119
0.020
Why?
Wound Healing
1
2007
108
0.020
Why?
Adult
1
2017
6826
0.010
Why?
Receptors, Purinergic P2
1
2005
1
0.010
Why?
Cytochromes c
1
2005
11
0.010
Why?
Adenosine Triphosphate
1
2005
19
0.010
Why?
Cyclosporine
1
2005
12
0.010
Why?
Middle Aged
1
2017
7800
0.010
Why?
Molecular Conformation
1
2004
10
0.010
Why?
Vanadates
1
2003
3
0.010
Why?
Jurkat Cells
1
2003
8
0.010
Why?
Precipitin Tests
1
2003
9
0.010
Why?
Electrophoresis, Polyacrylamide Gel
1
2003
24
0.010
Why?
Immunoblotting
1
2003
54
0.010
Why?
Plasmids
1
2003
43
0.010
Why?
Models, Genetic
1
2003
30
0.010
Why?
Mice, Transgenic
1
2003
175
0.010
Why?
Time Factors
1
2003
1247
0.010
Why?
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