 Interferon Regulatory Factors
"Interferon Regulatory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors that share an N-terminal HELIX-TURN-HELIX MOTIF and bind INTERFERON-inducible promoters to control GENE expression. IRF proteins bind specific DNA sequences such as interferon-stimulated response elements, interferon regulatory elements, and the interferon consensus sequence.
| Descriptor ID |
D050835
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| MeSH Number(s) |
D12.644.360.024.302 D12.776.157.057.050 D12.776.260.504 D12.776.476.024.385 D12.776.930.332
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factors".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factors".
This graph shows the total number of publications written about "Interferon Regulatory Factors" by people in this website by year, and whether "Interferon Regulatory Factors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factors" by people in Profiles.
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Chrabot BS, Kariuki SN, Zervou MI, Feng X, Arrington J, Jolly M, Boumpas DT, Reder AT, Goulielmos GN, Niewold TB. Genetic variation near IRF8 is associated with serologic and cytokine profiles in systemic lupus erythematosus and multiple sclerosis. Genes Immun. 2013 Dec; 14(8):471-8.
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De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat Genet. 2009 Jul; 41(7):776-82.
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