"Host Cell Factor C1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cellular transcriptional coactivator that contains N-terminal KELCH REPEATS and N- and C-terminal FIBRONECTIN TYPE III DOMAINS. It functions as a transcription factor for a number of genes and in the assembly of IMMEDIATE-EARLY PROTEINS of the HERPES SIMPLEX VIRUS. Mutations in the HCFC1 gene are associated with cases of X-LINKED MENTAL RETARDATION.
Descriptor ID |
D051863
|
MeSH Number(s) |
D12.776.660.478 D12.776.930.325
|
Concept/Terms |
Host Cell Factor C1- Host Cell Factor C1
- Cell Proliferation Factor HCF
- HCFC1 Protein
- C1 Host Cell Factor
|
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