"Protamines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of simple proteins that yield basic amino acids on hydrolysis and that occur combined with nucleic acid in the sperm of fish. Protamines contain very few kinds of amino acids. Protamine sulfate combines with heparin to form a stable inactive complex; it is used to neutralize the anticoagulant action of heparin in the treatment of heparin overdose. (From Merck Index, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p692)
| Descriptor ID |
D011479
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| MeSH Number(s) |
D12.776.660.750 D12.776.664.750
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Protamines".
Below are MeSH descriptors whose meaning is more specific than "Protamines".
This graph shows the total number of publications written about "Protamines" by people in this website by year, and whether "Protamines" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protamines" by people in Profiles.
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Heparin reversal with protamine sulfate is not required in atrial fibrillation ablation with suture hemostasis. J Cardiovasc Electrophysiol. 2019 12; 30(12):2811-2817.
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Characterization and performance of nucleic acid nanoparticles combined with protamine and gold. Biomaterials. 2009 Nov; 30(32):6451-9.
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Regulation of mouse podocyte process dynamics by protein tyrosine phosphatases rapid communication. Kidney Int. 2000 May; 57(5):2035-42.
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Evaluation of coagulation during cardiopulmonary bypass with a heparinase-modified thromboelastographic assay. J Cardiothorac Vasc Anesth. 1994 Apr; 8(2):144-9.
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Comparison of viscoelastic measures of coagulation after cardiopulmonary bypass. Anesth Analg. 1989 Jul; 69(1):69-75.
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C-reactive protein is involved in natural killer cell-mediated lysis but does not mediate effector-target cell recognition. Immunology. 1987 May; 61(1):93-9.
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The role of basic substances of high molecular weight in the generalized Shwartzman reaction (GSR). Arzneimittelforschung. 1974 Oct; 24(10):1585-8.