"POU Domain Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.
| Descriptor ID |
D050809
|
| MeSH Number(s) |
D12.776.260.655 D12.776.930.710
|
| Concept/Terms |
POU Domain Factors- POU Domain Factors
- Pit-Oct-Unc Proteins
- Pit Oct Unc Proteins
- POU Proteins
- Transcription Factor POU
- POU, Transcription Factor
|
Below are MeSH descriptors whose meaning is more general than "POU Domain Factors".
Below are MeSH descriptors whose meaning is more specific than "POU Domain Factors".
This graph shows the total number of publications written about "POU Domain Factors" by people in this website by year, and whether "POU Domain Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2018 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "POU Domain Factors" by people in Profiles.
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Shared Causal Paths underlying Alzheimer's dementia and Type 2 Diabetes. Sci Rep. 2020 03 05; 10(1):4107.
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The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Sci Transl Med. 2018 12 19; 10(472).