"Sequestosome-1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multidomain protein that is highly conserved among multicellular organisms. It contains a ZZ-type ZINC FINGER domain, C-terminal UBIQUITIN - associated (UBA) domain, and interacts with many other signaling proteins and enzymes including, atypical PROTEIN KINASE C; TNF RECEPTOR-ASSOCIATED FACTOR 6; subunits of the mTORC1 complex, and CASPASE-8. It functions in AUTOPHAGY as a receptor for the degradation of ubiquitinated substrates, and to co-ordinate signaling in response to OXIDATIVE STRESS.
| Descriptor ID |
D000071456
|
| MeSH Number(s) |
D12.644.360.024.329 D12.776.094.750 D12.776.157.057.160 D12.776.476.024.422
|
| Concept/Terms |
Sequestosome-1 Protein- Sequestosome-1 Protein
- Sequestosome 1 Protein
- Ubiquitin-Binding Protein p62
- Ubiquitin Binding Protein p62
- Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 Kda
- Phosphotyrosine Independent Ligand For The Lck SH2 Domain Of 62 Kda
- EBI3-Associated Protein of 60 KDa
- EBI3 Associated Protein of 60 KDa
- EBIAP Protein
|
Below are MeSH descriptors whose meaning is more general than "Sequestosome-1 Protein".
Below are MeSH descriptors whose meaning is more specific than "Sequestosome-1 Protein".
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