"Caveolin 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tyrosine phosphoprotein that plays an essential role in CAVEOLAE formation. It binds CHOLESTEROL and is involved in LIPIDS transport, membrane traffic, and SIGNAL TRANSDUCTION.
| Descriptor ID |
D051242
|
| MeSH Number(s) |
D12.644.360.024.264 D12.776.157.057.010 D12.776.476.024.280 D12.776.543.990.100.500 D12.776.744.287
|
| Concept/Terms |
Caveolin 1- Caveolin 1
- Vesicular Integral Membrane Protein 21 kDa
- Caveolin-1
- VIP21 Protein
|
Below are MeSH descriptors whose meaning is more general than "Caveolin 1".
Below are MeSH descriptors whose meaning is more specific than "Caveolin 1".
This graph shows the total number of publications written about "Caveolin 1" by people in this website by year, and whether "Caveolin 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 1 | 2 |
| 2007 | 3 | 0 | 3 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caveolin 1" by people in Profiles.
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Molecular Changes Associated with the Protective Effects of Angiopoietin-1 During Blood-Brain Barrier Breakdown Post-Injury. Mol Neurobiol. 2017 08; 54(6):4232-4242.
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Caveolin-1 overexpression is associated with hepatocellular carcinoma tumourigenesis and metastasis. J Pathol. 2012 Mar; 226(4):645-53.
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Pathology and new players in the pathogenesis of brain edema. Acta Neuropathol. 2009 Aug; 118(2):197-217.
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Decreased junctional adhesion molecule-A expression during blood-brain barrier breakdown. Acta Neuropathol. 2008 Jun; 115(6):635-42.
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Role of NF-kappaB-dependent caveolin-1 expression in the mechanism of increased endothelial permeability induced by lipopolysaccharide. J Biol Chem. 2008 Feb 15; 283(7):4210-8.
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Increased caveolin-1 expression precedes decreased expression of occludin and claudin-5 during blood-brain barrier breakdown. Acta Neuropathol. 2007 Nov; 114(5):459-69.
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Caveolin 1 is overexpressed and amplified in a subset of basal-like and metaplastic breast carcinomas: a morphologic, ultrastructural, immunohistochemical, and in situ hybridization analysis. Clin Cancer Res. 2007 Jan 01; 13(1):90-101.
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siRNA-induced caveolin-1 knockdown in mice increases lung vascular permeability via the junctional pathway. Am J Physiol Lung Cell Mol Physiol. 2006 Feb; 290(2):L405-13.
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Cholesterol-dependent syntaxin-4 and SNAP-23 clustering regulates caveolar fusion with the endothelial plasma membrane. J Biol Chem. 2005 Nov 04; 280(44):37130-8.