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Ali Keshavarzian

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentInternal Medicine, Division of Digestive Diseases and Nutrition
Address1725 W. Harrison St.
Chicago IL 60612
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    Collapse Overview 
    Collapse overview
    Other Positions:
    Josephine M. Dyrenforth Chair of Gastroenterology
    Professor of Medicine, Rush Medical College
    Professor, Graduate College

    My Scopus ID is 7006447140.
    My NIH COMMONS name is AKESHAVARZIAN.

    Education:
    MD, Tehran University School of Medical Sciences, Iran, 1976


    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Perez-Pardo P, Kliest T, Dodiya HB, Broersen LM, Garssen J, Keshavarzian A, Kraneveld AD. The gut-brain axis in Parkinson's disease: Possibilities for food-based therapies. Eur J Pharmacol. 2017 May 23. PMID: 28549787.
      View in: PubMed
    2. Yang AM, Inamine T, Hochrath K, Chen P, Wang L, Llorente C, Bluemel S, Hartmann P, Xu J, Koyama Y, Kisseleva T, Torralba MG, Moncera K, Beeri K, Chen CS, Freese K, Hellerbrand C, Lee SM, Hoffman HM, Mehal WZ, Garcia-Tsao G, Mutlu EA, Keshavarzian A, Brown GD, Ho SB, Bataller R, Stärkel P, Fouts DE, Schnabl B. Intestinal fungi contribute to development of alcoholic liver disease. J Clin Invest. 2017 May 22. PMID: 28530644.
      View in: PubMed
    3. Chen T, Kim CY, Kaur A, Lamothe L, Shaikh M, Keshavarzian A, Hamaker BR. Dietary fibre-based SCFA mixtures promote both protection and repair of intestinal epithelial barrier function in a Caco-2 cell model. Food Funct. 2017 Mar 22; 8(3):1166-1173. PMID: 28174773.
      View in: PubMed
    4. Lu R, Voigt RM, Zhang Y, Kato I, Xia Y, Forsyth CB, Keshavarzian A, Sun J. Alcohol Injury Damages Intestinal Stem Cells. Alcohol Clin Exp Res. 2017 Apr; 41(4):727-734. PMID: 28195397.
      View in: PubMed
    5. Perez-Pardo P, Dodiya HB, Broersen LM, Douna H, van Wijk N, Lopes da Silva S, Garssen J, Keshavarzian A, Kraneveld AD. Gut-brain and brain-gut axis in Parkinson's disease models: Effects of a uridine and fish oil diet. Nutr Neurosci. 2017 Mar 09; 1-12. PMID: 28276272.
      View in: PubMed
    6. Mahdavinia M, Schleimer RP, Keshavarzian A. Sleep disruption in chronic rhinosinusitis. Expert Rev Anti Infect Ther. 2017 May; 15(5):457-465. PMID: 28276943.
      View in: PubMed
    7. Engen PA, Dodiya HB, Naqib A, Forsyth CB, Green SJ, Voigt RM, Kordower JH, Mutlu EA, Shannon KM, Keshavarzian A. The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy. J Parkinsons Dis. 2017; 7(2):331-346. PMID: 28234259.
      View in: PubMed
    8. Mackus M, Adams S, Barzilay A, Benson S, Blau L, Iversen J, Johnson SJ, Keshavarzian A, Scholey A, Smith GS, Trela C, Vatsalya V, Verster JC. Proceeding of the 8th Alcohol Hangover Research Group Meeting. Curr Drug Abuse Rev. 2016 Dec 29. PMID: 28034278.
      View in: PubMed
    9. Rumpagaporn P, Reuhs BL, Cantu-Jungles TM, Kaur A, Patterson JA, Keshavarzian A, Hamaker BR. Elevated propionate and butyrate in fecal ferments of hydrolysates generated by oxalic acid treatment of corn bran arabinoxylan. Food Funct. 2016 Dec 07; 7(12):4935-4943. PMID: 27841429.
      View in: PubMed
    10. Bishehsari F, Saadalla A, Khazaie K, Engen PA, Voigt RM, Shetuni BB, Forsyth C, Shaikh M, Vitaterna MH, Turek F, Keshavarzian A. Light/Dark Shifting Promotes Alcohol-Induced Colon Carcinogenesis: Possible Role of Intestinal Inflammatory Milieu and Microbiota. Int J Mol Sci. 2016 Dec 02; 17(12). PMID: 27918452.
      View in: PubMed
    11. Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet MF, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, Knight R, Mazmanian SK. Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease. Cell. 2016 Dec 01; 167(6):1469-1480.e12. PMID: 27912057.
      View in: PubMed
    12. Voigt RM, Forsyth CB, Green SJ, Engen PA, Keshavarzian A. Circadian Rhythm and the Gut Microbiome. Int Rev Neurobiol. 2016; 131:193-205. PMID: 27793218.
      View in: PubMed
    13. Bishehsari F, Levi F, Turek FW, Keshavarzian A. Circadian Rhythms in Gastrointestinal Health and Diseases. Gastroenterology. 2016 Sep; 151(3):e1-5. PMID: 27480174; PMCID: PMC5002365 [Available on 09/01/17].
    14. Swanson GR, Gorenz A, Shaikh M, Desai V, Kaminsky T, Van Den Berg J, Murphy T, Raeisi S, Fogg L, Vitaterna MH, Forsyth C, Turek F, Burgess HJ, Keshavarzian A. Night workers with circadian misalignment are susceptible to alcohol-induced intestinal hyperpermeability with social drinking. Am J Physiol Gastrointest Liver Physiol. 2016 Jul 01; 311(1):G192-201. PMID: 27198191; PMCID: PMC4967173 [Available on 07/01/17].
    15. Yazici C, Arslan DC, Abraham R, Cushing K, Keshavarzian A, Mutlu EA. Breath Methane Levels Are Increased Among Patients with Diverticulosis. Dig Dis Sci. 2016 Sep; 61(9):2648-54. PMID: 27129485.
      View in: PubMed
    16. Verhaegh BP, de Vries F, Masclee AA, Keshavarzian A, de Boer A, Souverein PC, Pierik MJ, Jonkers DM. High risk of drug-induced microscopic colitis with concomitant use of NSAIDs and proton pump inhibitors. Aliment Pharmacol Ther. 2016 May; 43(9):1004-13. PMID: 26956016.
      View in: PubMed
    17. Burgess HJ, Rizvydeen M, Fogg LF, Keshavarzian A. A single dose of alcohol does not meaningfully alter circadian phase advances and phase delays to light in humans. Am J Physiol Regul Integr Comp Physiol. 2016 Apr 15; 310(8):R759-65. PMID: 26936778; PMCID: PMC4867406 [Available on 04/15/17].
    18. Shobar RM, Velineni S, Keshavarzian A, Swanson G, DeMeo MT, Melson JE, Losurdo J, Engen PA, Sun Y, Koenig L, Mutlu EA. The Effects of Bowel Preparation on Microbiota-Related Metrics Differ in Health and in Inflammatory Bowel Disease and for the Mucosal and Luminal Microbiota Compartments. Clin Transl Gastroenterol. 2016 Feb 11; 7:e143. PMID: 26866392; PMCID: PMC4817412.
    19. Miller GE, Engen PA, Gillevet PM, Shaikh M, Sikaroodi M, Forsyth CB, Mutlu E, Keshavarzian A. Lower Neighborhood Socioeconomic Status Associated with Reduced Diversity of the Colonic Microbiota in Healthy Adults. PLoS One. 2016; 11(2):e0148952. PMID: 26859894; PMCID: PMC4747579.
    20. Patel AL, Mutlu EA, Sun Y, Koenig L, Green S, Jakubowicz A, Mryan J, Engen P, Fogg L, Chen AL, Pombar X, Meier PP, Keshavarzian A. Longitudinal Survey of Microbiota in Hospitalized Preterm Very-Low-Birth-Weight Infants. J Pediatr Gastroenterol Nutr. 2016 Feb; 62(2):292-303. PMID: 26230901; PMCID: PMC4724288 [Available on 02/01/17].
    21. Voigt RM, Summa KC, Forsyth CB, Green SJ, Engen P, Naqib A, Vitaterna MH, Turek FW, Keshavarzian A. The Circadian Clock Mutation Promotes Intestinal Dysbiosis. Alcohol Clin Exp Res. 2016 Feb; 40(2):335-47. PMID: 26842252; PMCID: PMC4977829 [Available on 02/01/17].
    22. Mahdavinia M, Benhammuda M, Codispoti CD, Tobin MC, Losavio PS, Mehta A, Jeffe JS, Bandi S, Peters AT, Stevens WW, Landay A, Keshavarzian A, Schleimer RP, Batra PS. African American Patients with Chronic Rhinosinusitis Have a Distinct Phenotype of Polyposis Associated with Increased Asthma Hospitalization. J Allergy Clin Immunol Pract. 2016 Jul-Aug; 4(4):658-664.e1. PMID: 26868728.
      View in: PubMed
    23. Mahdavinia M, Keshavarzian A, Tobin MC, Landay AL, Schleimer RP. A comprehensive review of the nasal microbiome in chronic rhinosinusitis (CRS). Clin Exp Allergy. 2016 Jan; 46(1):21-41. PMID: 26510171; PMCID: PMC4715613 [Available on 01/01/17].
    24. Kc R, Li X, Forsyth CB, Voigt RM, Summa KC, Vitaterna MH, Tryniszewska B, Keshavarzian A, Turek FW, Meng QJ, Im HJ. Osteoarthritis-like pathologic changes in the knee joint induced by environmental disruption of circadian rhythms is potentiated by a high-fat diet. Sci Rep. 2015 Nov 20; 5:16896. PMID: 26584570; PMCID: PMC4653622.
    25. Phua LC, Wilder-Smith CH, Tan YM, Gopalakrishnan T, Wong RK, Li X, Kan ME, Lu J, Keshavarzian A, Chan EC. Gastrointestinal Symptoms and Altered Intestinal Permeability Induced by Combat Training Are Associated with Distinct Metabotypic Changes. J Proteome Res. 2015 Nov 06; 14(11):4734-42. PMID: 26506213.
      View in: PubMed
    26. Patel S, Behara R, Swanson GR, Forsyth CB, Voigt RM, Keshavarzian A. Alcohol and the Intestine. Biomolecules. 2015 Oct 15; 5(4):2573-88. PMID: 26501334; PMCID: PMC4693248.
    27. Summa KC, Jiang P, Fitzpatrick K, Voigt RM, Bowers SJ, Forsyth CB, Vitaterna MH, Keshavarzian A, Turek FW. Chronic Alcohol Exposure and the Circadian Clock Mutation Exert Tissue-Specific Effects on Gene Expression in Mouse Hippocampus, Liver, and Proximal Colon. Alcohol Clin Exp Res. 2015 Oct; 39(10):1917-29. PMID: 26332085; PMCID: PMC4562391 [Available on 10/01/16].
    28. Pal GD, Shaikh M, Forsyth CB, Ouyang B, Keshavarzian A, Shannon KM. Abnormal lipopolysaccharide binding protein as marker of gastrointestinal inflammation in Parkinson disease. Front Neurosci. 2015; 9:306. PMID: 26388718; PMCID: PMC4555963.
    29. Swanson G, Rizvydeen M, Burgess H, Keshavarzian A. Response to Dr. Kawada. Am J Physiol Gastrointest Liver Physiol. 2015 Aug 15; 309(4):G280. PMID: 26276973.
      View in: PubMed
    30. Tang Y, Zhang L, Forsyth CB, Shaikh M, Song S, Keshavarzian A. The Role of miR-212 and iNOS in Alcohol-Induced Intestinal Barrier Dysfunction and Steatohepatitis. Alcohol Clin Exp Res. 2015 Sep; 39(9):1632-41. PMID: 26207424; PMCID: PMC4558329.
    31. Keshavarzian A, Green SJ, Engen PA, Voigt RM, Naqib A, Forsyth CB, Mutlu E, Shannon KM. Colonic bacterial composition in Parkinson's disease. Mov Disord. 2015 Sep; 30(10):1351-60. PMID: 26179554.
      View in: PubMed
    32. Moossavi S, Bishehsari F, Ansari R, Vahedi H, Nasseri-Moghaddam S, Merat S, Sobhani I, Keshavarzian A, Malekzadeh R. Minimum Requirements for Reporting Fecal Microbiota Transplant Trial. Middle East J Dig Dis. 2015 Jul; 7:177-80. PMID: 26396721; PMCID: PMC4560633.
    33. Kc R, Voigt R, Li X, Forsyth CB, Ellman MB, Summa KC, Turek FW, Keshavarzian A, Kim JS, Im HJ. Induction of Osteoarthritis-like Pathologic Changes by Chronic Alcohol Consumption in an Experimental Mouse Model. Arthritis Rheumatol. 2015 Jun; 67(6):1678-80. PMID: 25708245; PMCID: PMC4823794.
    34. Rumpagaporn P, Reuhs BL, Kaur A, Patterson JA, Keshavarzian A, Hamaker BR. Structural features of soluble cereal arabinoxylan fibers associated with a slow rate of in vitro fermentation by human fecal microbiota. Carbohydr Polym. 2015 Oct 05; 130:191-7. PMID: 26076616.
      View in: PubMed
    35. Swanson GR, Gorenz A, Shaikh M, Desai V, Forsyth C, Fogg L, Burgess HJ, Keshavarzian A. Decreased melatonin secretion is associated with increased intestinal permeability and marker of endotoxemia in alcoholics. Am J Physiol Gastrointest Liver Physiol. 2015 Jun 15; 308(12):G1004-11. PMID: 25907689; PMCID: PMC4469868.
    36. Jedel S, Hood MM, Keshavarzian A. Getting personal: a review of sexual functioning, body image, and their impact on quality of life in patients with inflammatory bowel disease. Inflamm Bowel Dis. 2015 Apr; 21(4):923-38. PMID: 25789923; PMCID: PMC4369789.
    37. Voigt RM, Keshavarzian A, Losurdo J, Swanson G, Siewe B, Forsyth CB, French AL, Demarais P, Engen P, Raeisi S, Mutlu E, Landay AL. HIV-associated mucosal gene expression: region-specific alterations. AIDS. 2015 Mar 13; 29(5):537-46. PMID: 25587909; PMCID: PMC4791036.
    38. Couch RD, Dailey A, Zaidi F, Navarro K, Forsyth CB, Mutlu E, Engen PA, Keshavarzian A. Alcohol induced alterations to the human fecal VOC metabolome. PLoS One. 2015; 10(3):e0119362. PMID: 25751150; PMCID: PMC4353727.
    39. Norman JM, Handley SA, Baldridge MT, Droit L, Liu CY, Keller BC, Kambal A, Monaco CL, Zhao G, Fleshner P, Stappenbeck TS, McGovern DP, Keshavarzian A, Mutlu EA, Sauk J, Gevers D, Xavier RJ, Wang D, Parkes M, Virgin HW. Disease-specific alterations in the enteric virome in inflammatory bowel disease. Cell. 2015 Jan 29; 160(3):447-60. PMID: 25619688; PMCID: PMC4312520.
    40. Shaikh M, Rajan K, Forsyth CB, Voigt RM, Keshavarzian A. Simultaneous gas-chromatographic urinary measurement of sugar probes to assess intestinal permeability: use of time course analysis to optimize its use to assess regional gut permeability. Clin Chim Acta. 2015 Mar 10; 442:24-32. PMID: 25591964; PMCID: PMC4339548.
    41. Wisittipanit N, Rangwala H, Sikaroodi M, Keshavarzian A, Mutlu EA, Gillevet P. Classification methods for the analysis of LH-PCR data associated with inflammatory bowel disease patients. Int J Bioinform Res Appl. 2015; 11(2):111-29. PMID: 25786791.
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    42. Engen PA, Green SJ, Voigt RM, Forsyth CB, Keshavarzian A. The Gastrointestinal Microbiome: Alcohol Effects on the Composition of Intestinal Microbiota. Alcohol Res. 2015; 37(2):223-36. PMID: 26695747; PMCID: PMC4590619.
    43. Bashashati M, Habibi HR, Keshavarzian A, Schmulson M, Sharkey KA. Intestinal microbiota: a regulator of intestinal inflammation and cardiac ischemia? Curr Drug Targets. 2015; 16(3):199-208. PMID: 25601328.
      View in: PubMed
    44. Forsyth CB, Voigt RM, Burgess HJ, Swanson GR, Keshavarzian A. Circadian rhythms, alcohol and gut interactions. Alcohol. 2015 Jun; 49(4):389-98. PMID: 25499101; PMCID: PMC4431951.
    45. Ben Musa R, Gampa A, Basu S, Keshavarzian A, Swanson G, Brown M, Abraham R, Bruninga K, Losurdo J, DeMeo M, Mobarhan S, Shapiro D, Mutlu E. Hepatitis B vaccination in patients with inflammatory bowel disease. World J Gastroenterol. 2014 Nov 07; 20(41):15358-66. PMID: 25386085; PMCID: PMC4223270.
    46. de Kivit S, Lempsink LJ, Plants J, Martinson J, Keshavarzian A, Landay AL. Modulation of TIM-3 expression on NK and T cell subsets in HIV immunological non-responders. Clin Immunol. 2015 Jan; 156(1):28-35. PMID: 25450337.
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    47. Forsyth CB, Voigt RM, Keshavarzian A. Intestinal CYP2E1: A mediator of alcohol-induced gut leakiness. Redox Biol. 2014; 3:40-6. PMID: 25462064; PMCID: PMC4297927.
    48. Chen P, Torralba M, Tan J, Embree M, Zengler K, Stärkel P, van Pijkeren JP, DePew J, Loomba R, Ho SB, Bajaj JS, Mutlu EA, Keshavarzian A, Tsukamoto H, Nelson KE, Fouts DE, Schnabl B. Supplementation of saturated long-chain fatty acids maintains intestinal eubiosis and reduces ethanol-induced liver injury in mice. Gastroenterology. 2015 Jan; 148(1):203-214.e16. PMID: 25239591; PMCID: PMC4274236.
    49. Moore C, Jakate S, Keshavarzian A. An Esophagogastroduodenal Crohn's-Like Disease in a Long-Standing Pan-Ulcerative Colitis Patient. Case Rep Gastrointest Med. 2014; 2014:464139. PMID: 25295198; PMCID: PMC4176905.
    50. Tang Y, Forsyth CB, Keshavarzian A. The role of miRNAs in alcohol-induced endotoxemia, dysfunction of mucosal immunity, and gut leakiness. Alcohol Clin Exp Res. 2014 Sep; 38(9):2331-4. PMID: 25257284.
      View in: PubMed
    51. de Kivit S, Tobin MC, DeMeo MT, Fox S, Garssen J, Forsyth CB, Keshavarzian A, Landay AL. In vitro evaluation of intestinal epithelial TLR activation in preventing food allergic responses. Clin Immunol. 2014 Oct; 154(2):91-9. PMID: 25058467.
      View in: PubMed
    52. Voigt RM, Forsyth CB, Green SJ, Mutlu E, Engen P, Vitaterna MH, Turek FW, Keshavarzian A. Circadian disorganization alters intestinal microbiota. PLoS One. 2014; 9(5):e97500. PMID: 24848969; PMCID: PMC4029760.
    53. Keerthivasan S, Aghajani K, Dose M, Molinero L, Khan MW, Venkateswaran V, Weber C, Emmanuel AO, Sun T, Bentrem DJ, Mulcahy M, Keshavarzian A, Ramos EM, Blatner N, Khazaie K, Gounari F. ß-Catenin promotes colitis and colon cancer through imprinting of proinflammatory properties in T cells. Sci Transl Med. 2014 Feb 26; 6(225):225ra28. PMID: 24574339; PMCID: PMC4020714.
    54. Mutlu EA, Keshavarzian A, Losurdo J, Swanson G, Siewe B, Forsyth C, French A, Demarais P, Sun Y, Koenig L, Cox S, Engen P, Chakradeo P, Abbasi R, Gorenz A, Burns C, Landay A. A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects. PLoS Pathog. 2014 Feb; 10(2):e1003829. PMID: 24586144; PMCID: PMC3930561.
    55. de Kivit S, Tobin MC, Forsyth CB, Keshavarzian A, Landay AL. Regulation of Intestinal Immune Responses through TLR Activation: Implications for Pro- and Prebiotics. Front Immunol. 2014; 5:60. PMID: 24600450; PMCID: PMC3927311.
    56. Jedel S, Hoffman A, Merriman P, Swanson B, Voigt R, Rajan KB, Shaikh M, Li H, Keshavarzian A. A randomized controlled trial of mindfulness-based stress reduction to prevent flare-up in patients with inactive ulcerative colitis. Digestion. 2014; 89(2):142-55. PMID: 24557009; PMCID: PMC4059005.
    57. Couch RD, Navarro K, Sikaroodi M, Gillevet P, Forsyth CB, Mutlu E, Engen PA, Keshavarzian A. The approach to sample acquisition and its impact on the derived human fecal microbiome and VOC metabolome. PLoS One. 2013; 8(11):e81163. PMID: 24260553; PMCID: PMC3832442.
    58. Gandhi S, Jedel S, Hood MM, Mutlu E, Swanson G, Keshavarzian A. The relationship between coping, health competence and patient participation among patients with inactive inflammatory bowel disease. J Crohns Colitis. 2014 May; 8(5):401-8. PMID: 24230968.
      View in: PubMed
    59. Kelly LP, Carvey PM, Keshavarzian A, Shannon KM, Shaikh M, Bakay RA, Kordower JH. Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease. Mov Disord. 2014 Jul; 29(8):999-1009. PMID: 24898698; PMCID: PMC4050039.
    60. Swanson G, Behara R, Braun R, Keshavarzian A. Diagnostic medical radiation in inflammatory bowel disease: how to limit risk and maximize benefit. Inflamm Bowel Dis. 2013 Oct; 19(11):2501-8. PMID: 23792551.
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    61. Abdelmegeed MA, Banerjee A, Jang S, Yoo SH, Yun JW, Gonzalez FJ, Keshavarzian A, Song BJ. CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis, and apoptosis. Free Radic Biol Med. 2013 Dec; 65:1238-45. PMID: 24064383; PMCID: PMC3859835.
    62. Yang J, Keshavarzian A, Rose DJ. Impact of dietary fiber fermentation from cereal grains on metabolite production by the fecal microbiota from normal weight and obese individuals. J Med Food. 2013 Sep; 16(9):862-7. PMID: 24044495.
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    63. Siewe B, Keshavarzian A, French A, Demarais P, Landay A. A role for TLR signaling during B cell activation in antiretroviral-treated HIV individuals. AIDS Res Hum Retroviruses. 2013 Oct; 29(10):1353-60. PMID: 23763346; PMCID: PMC3785799.
    64. Yang J, Martínez I, Walter J, Keshavarzian A, Rose DJ. In vitro characterization of the impact of selected dietary fibers on fecal microbiota composition and short chain fatty acid production. Anaerobe. 2013 Oct; 23:74-81. PMID: 23831725.
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    65. Summa KC, Voigt RM, Forsyth CB, Shaikh M, Cavanaugh K, Tang Y, Vitaterna MH, Song S, Turek FW, Keshavarzian A. Disruption of the Circadian Clock in Mice Increases Intestinal Permeability and Promotes Alcohol-Induced Hepatic Pathology and Inflammation. PLoS One. 2013; 8(6):e67102. PMID: 23825629; PMCID: PMC3688973.
    66. Forsyth CB, Voigt RM, Shaikh M, Tang Y, Cederbaum AI, Turek FW, Keshavarzian A. Role for intestinal CYP2E1 in alcohol-induced circadian gene-mediated intestinal hyperpermeability. Am J Physiol Gastrointest Liver Physiol. 2013 Jul 15; 305(2):G185-95. PMID: 23660503; PMCID: PMC3725682.
    67. Khan MW, Keshavarzian A, Gounaris E, Melson JE, Cheon EC, Blatner NR, Chen ZE, Tsai FN, Lee G, Ryu H, Barrett TA, Bentrem DJ, Beckhove P, Khazaie K. PI3K/AKT signaling is essential for communication between tissue-infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer. Clin Cancer Res. 2013 May 01; 19(9):2342-54. PMID: 23487439; PMCID: PMC3947836.
    68. Li X, Kan EM, Lu J, Cao Y, Wong RK, Keshavarzian A, Wilder-Smith CH. Combat-training increases intestinal permeability, immune activation and gastrointestinal symptoms in soldiers. Aliment Pharmacol Ther. 2013 Apr; 37(8):799-809. PMID: 23432460.
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    69. Skarupski KA, Keshavarzian A. Investing in academic medicine research mentoring: low cost, high return. Gastroenterology. 2013 Apr; 144(4):e21-2. PMID: 23462123.
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    70. Siewe B, Stapleton JT, Martinson J, Keshavarzian A, Kazmi N, Demarais PM, French AL, Landay A. Regulatory B cell frequency correlates with markers of HIV disease progression and attenuates anti-HIV CD8? T cell function in vitro. J Leukoc Biol. 2013 May; 93(5):811-8. PMID: 23434518; PMCID: PMC3629440.
    71. Wood S, Pithadia R, Rehman T, Zhang L, Plichta J, Radek KA, Forsyth C, Keshavarzian A, Shafikhani SH. Chronic alcohol exposure renders epithelial cells vulnerable to bacterial infection. PLoS One. 2013; 8(1):e54646. PMID: 23358457; PMCID: PMC3554638.
    72. Wimberly AL, Forsyth CB, Khan MW, Pemberton A, Khazaie K, Keshavarzian A. Ethanol-induced mast cell-mediated inflammation leads to increased susceptibility of intestinal tumorigenesis in the APC ?468 min mouse model of colon cancer. Alcohol Clin Exp Res. 2013 Jan; 37 Suppl 1:E199-208. PMID: 23320800; PMCID: PMC3694334.
    73. Voigt RM, Forsyth CB, Keshavarzian A. Circadian disruption: potential implications in inflammatory and metabolic diseases associated with alcohol. Alcohol Res. 2013; 35(1):87-96. PMID: 24313168; PMCID: PMC3860420.
    74. Yazici C, Losurdo J, Brown MD, Oosterveen S, Rahimi R, Keshavarzian A, Bozorgnia L, Mutlu E. Inpatient capsule endoscopy leads to frequent incomplete small bowel examinations. World J Gastroenterol. 2012 Sep 28; 18(36):5051-7. PMID: 23049213; PMCID: PMC3460331.
    75. Gallegos M, Bradly D, Jakate S, Keshavarzian A. Lymphogranuloma venereum proctosigmoiditis is a mimicker of inflammatory bowel disease. World J Gastroenterol. 2012 Jul 07; 18(25):3317-21. PMID: 22783058; PMCID: PMC3391771.
    76. Broucek JR, Francescatti AB, Swanson GR, Keshavarzian A, Brand MI, Saclarides TJ. Unusual thrombotic complications. Am Surg. 2012 Jun; 78(6):728-9. PMID: 22643273.
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    77. Shannon KM, Keshavarzian A, Dodiya HB, Jakate S, Kordower JH. Is alpha-synuclein in the colon a biomarker for premotor Parkinson's disease? Evidence from 3 cases. Mov Disord. 2012 May; 27(6):716-9. PMID: 22550057.
      View in: PubMed
    78. Mutlu EA, Gillevet PM, Rangwala H, Sikaroodi M, Naqvi A, Engen PA, Kwasny M, Lau CK, Keshavarzian A. Colonic microbiome is altered in alcoholism. Am J Physiol Gastrointest Liver Physiol. 2012 May 01; 302(9):G966-78. PMID: 22241860; PMCID: PMC3362077.
    79. Jedel S, Hankin V, Voigt RM, Keshavarzian A. Addressing the mind, body, and spirit in a gastrointestinal practice for inflammatory bowel disease patients. Clin Gastroenterol Hepatol. 2012 Mar; 10(3):244-6. PMID: 22172296; PMCID: PMC3744096.
    80. Forsyth CB, Shannon KM, Kordower JH, Voigt RM, Shaikh M, Jaglin JA, Estes JD, Dodiya HB, Keshavarzian A. Increased intestinal permeability correlates with sigmoid mucosa alpha-synuclein staining and endotoxin exposure markers in early Parkinson's disease. PLoS One. 2011; 6(12):e28032. PMID: 22145021; PMCID: PMC3228722.
    81. Tang Y, Forsyth CB, Keshavarzian A. New molecular insights into inflammatory bowel disease-induced diarrhea. Expert Rev Gastroenterol Hepatol. 2011 Oct; 5(5):615-25. PMID: 21910579; PMCID: PMC3227675.
    82. Swanson GR, Tieu V, Shaikh M, Forsyth C, Keshavarzian A. Is moderate red wine consumption safe in inactive inflammatory bowel disease? Digestion. 2011; 84(3):238-44. PMID: 21876358; PMCID: PMC3180655.
    83. Shannon KM, Keshavarzian A, Mutlu E, Dodiya HB, Daian D, Jaglin JA, Kordower JH. Alpha-synuclein in colonic submucosa in early untreated Parkinson's disease. Mov Disord. 2012 May; 27(6):709-15. PMID: 21766334.
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    85. Gallegos M, Lau C, Bradly DP, Blanco L, Keshavarzian A, Jakate SM. Cap polyposis with protein-losing enteropathy. Gastroenterol Hepatol (N Y). 2011 Jun; 7(6):415-20. PMID: 21869875; PMCID: PMC3151416.
    86. Forsyth CB, Tang Y, Shaikh M, Zhang L, Keshavarzian A. Role of snail activation in alcohol-induced iNOS-mediated disruption of intestinal epithelial cell permeability. Alcohol Clin Exp Res. 2011 Sep; 35(9):1635-43. PMID: 21535025; PMCID: PMC3698619.
    87. Dixon E, Clubb C, Pittman S, Ammann L, Rasheed Z, Kazmi N, Keshavarzian A, Gillevet P, Rangwala H, Couch RD. Solid-phase microextraction and the human fecal VOC metabolome. PLoS One. 2011 Apr 08; 6(4):e18471. PMID: 21494609; PMCID: PMC3072975.
    88. Swanson G, Forsyth CB, Tang Y, Shaikh M, Zhang L, Turek FW, Keshavarzian A. Role of intestinal circadian genes in alcohol-induced gut leakiness. Alcohol Clin Exp Res. 2011 Jul; 35(7):1305-14. PMID: 21463335; PMCID: PMC3116965.
    89. Swanson GR, Burgess HJ, Keshavarzian A. Sleep disturbances and inflammatory bowel disease: a potential trigger for disease flare? Expert Rev Clin Immunol. 2011 Jan; 7(1):29-36. PMID: 21162647; PMCID: PMC3046047.
    90. Ponemone V, Keshavarzian A, Brand MI, Saclarides T, Abcarian H, Cabay RJ, Fletcher E, Larsen B, Durstine LJ, Fantuzzi G, Fayad R. Apoptosis and inflammation: role of adipokines in inflammatory bowel disease. Clin Transl Gastroenterol. 2010 Oct 21; 1:e1. PMID: 23238652; PMCID: PMC3365665.
    91. Melson JE, Giusto D, Kwasny M, Eichenseer P, Jakate S, Keshavarzian A. Histopathology predictors of medically refractory ulcerative colitis. Dis Colon Rectum. 2010 Sep; 53(9):1280-6. PMID: 20706071.
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    92. Farhadi A, Keshavarzian A, Kwasny MJ, Shaikh M, Fogg L, Lau C, Fields JZ, Forsyth CB. Effects of aspirin on gastroduodenal permeability in alcoholics and controls. Alcohol. 2010 Aug; 44(5):447-56. PMID: 20598487; PMCID: PMC2932827.
    93. Burgess HJ, Swanson GR, Keshavarzian A. Endogenous melatonin profiles in asymptomatic inflammatory bowel disease. Scand J Gastroenterol. 2010 Jun; 45(6):759-61. PMID: 20345337; PMCID: PMC3616441.
    94. Singhal S, Dian D, Keshavarzian A, Fogg L, Fields JZ, Farhadi A. The role of oral hygiene in inflammatory bowel disease. Dig Dis Sci. 2011 Jan; 56(1):170-5. PMID: 20458622.
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    95. Swanson GR, Sedghi S, Farhadi A, Keshavarzian A. Pattern of alcohol consumption and its effect on gastrointestinal symptoms in inflammatory bowel disease. Alcohol. 2010 May; 44(3):223-8. PMID: 20682190; PMCID: PMC3708696.
    96. Naqvi A, Rangwala H, Keshavarzian A, Gillevet P. Network-based modeling of the human gut microbiome. Chem Biodivers. 2010 May; 7(5):1040-50. PMID: 20491063; PMCID: PMC3681515.
    97. Gillevet P, Sikaroodi M, Keshavarzian A, Mutlu EA. Quantitative assessment of the human gut microbiome using multitag pyrosequencing. Chem Biodivers. 2010 May; 7(5):1065-75. PMID: 20491064; PMCID: PMC3748609.
    98. Hayden DM, Forsyth C, Keshavarzian A. The role of matrix metalloproteinases in intestinal epithelial wound healing during normal and inflammatory states. J Surg Res. 2011 Jun 15; 168(2):315-24. PMID: 20655064.
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    99. Frantzides CT, Carlson MA, Keshavarzian A, Roberts JE. Laparoscopic transgastric esophageal mucosal resection: 4-year minimum follow-up. Am J Surg. 2010 Aug; 200(2):305-7. PMID: 20188346.
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    100. Miranda RC, Pietrzykowski AZ, Tang Y, Sathyan P, Mayfield D, Keshavarzian A, Sampson W, Hereld D. MicroRNAs: master regulators of ethanol abuse and toxicity? Alcohol Clin Exp Res. 2010 Apr; 34(4):575-87. PMID: 20102566; PMCID: PMC2925252.
    101. Sohrabpour AA, Malekzadeh R, Keshavarzian A. Current therapeutic approaches in inflammatory bowel disease. Curr Pharm Des. 2010; 16(33):3668-83. PMID: 21128898.
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    102. Rose DJ, Venema K, Keshavarzian A, Hamaker BR. Starch-entrapped microspheres show a beneficial fermentation profile and decrease in potentially harmful bacteria during in vitro fermentation in faecal microbiota obtained from patients with inflammatory bowel disease. Br J Nutr. 2010 May; 103(10):1514-24. PMID: 20021704.
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    103. Forsyth CB, Tang Y, Shaikh M, Zhang L, Keshavarzian A. Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cells. Alcohol Clin Exp Res. 2010 Jan; 34(1):19-31. PMID: 19860811; PMCID: PMC3689303.
    104. Mutlu E, Keshavarzian A, Engen P, Forsyth CB, Sikaroodi M, Gillevet P. Intestinal dysbiosis: a possible mechanism of alcohol-induced endotoxemia and alcoholic steatohepatitis in rats. Alcohol Clin Exp Res. 2009 Oct; 33(10):1836-46. PMID: 19645728; PMCID: PMC3684271.
    105. Rose DJ, Keshavarzian A, Patterson JA, Venkatachalam M, Gillevet P, Hamaker BR. Starch-entrapped microspheres extend in vitro fecal fermentation, increase butyrate production, and influence microbiota pattern. Mol Nutr Food Res. 2009 May; 53 Suppl 1:S121-30. PMID: 18925612.
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    106. Tang Y, Preuss F, Turek FW, Jakate S, Keshavarzian A. Sleep deprivation worsens inflammation and delays recovery in a mouse model of colitis. Sleep Med. 2009 Jun; 10(6):597-603. PMID: 19403332; PMCID: PMC3509796.
    107. Tang Y, Forsyth CB, Farhadi A, Rangan J, Jakate S, Shaikh M, Banan A, Fields JZ, Keshavarzian A. Nitric oxide-mediated intestinal injury is required for alcohol-induced gut leakiness and liver damage. Alcohol Clin Exp Res. 2009 Jul; 33(7):1220-30. PMID: 19389191; PMCID: PMC2950098.
    108. Tang Y, Forsyth CB, Banan A, Fields JZ, Keshavarzian A. Oats supplementation prevents alcohol-induced gut leakiness in rats by preventing alcohol-induced oxidative tissue damage. J Pharmacol Exp Ther. 2009 Jun; 329(3):952-8. PMID: 19276402; PMCID: PMC2683774.
    109. Forsyth CB, Farhadi A, Jakate SM, Tang Y, Shaikh M, Keshavarzian A. Lactobacillus GG treatment ameliorates alcohol-induced intestinal oxidative stress, gut leakiness, and liver injury in a rat model of alcoholic steatohepatitis. Alcohol. 2009 Mar; 43(2):163-72. PMID: 19251117; PMCID: PMC2675276.
    110. Keshavarzian A, Farhadi A, Forsyth CB, Rangan J, Jakate S, Shaikh M, Banan A, Fields JZ. Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats. J Hepatol. 2009 Mar; 50(3):538-47. PMID: 19155080; PMCID: PMC2680133.
    111. Haddish-Berhane N, Farhadi A, Nyquist C, Haghighi K, Keshavarzian A. SIMDOT-AbMe: microphysiologically based simulation tool for quantitative prediction of systemic and local bioavailability of targeted oral delivery formulations. Drug Metab Dispos. 2009 Mar; 37(3):608-18. PMID: 19047471.
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    112. Preuss F, Tang Y, Laposky AD, Arble D, Keshavarzian A, Turek FW. Adverse effects of chronic circadian desynchronization in animals in a "challenging" environment. Am J Physiol Regul Integr Comp Physiol. 2008 Dec; 295(6):R2034-40. PMID: 18843092; PMCID: PMC2685296.
    113. Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, Kang YJ, Keshavarzian A, Rao R, Sartor RB, Swanson C, Turner JR. Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: summary of a symposium. Alcohol. 2008 Aug; 42(5):349-61. PMID: 18504085; PMCID: PMC2614138.
    114. Farhadi A, Gundlapalli S, Shaikh M, Frantzides C, Harrell L, Kwasny MM, Keshavarzian A. Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis. Liver Int. 2008 Aug; 28(7):1026-33. PMID: 18397235; PMCID: PMC4303249.
    115. Keefer L, Keshavarzian A, Mutlu E. Reconsidering the methodology of "stress" research in inflammatory bowel disease. J Crohns Colitis. 2008 Sep; 2(3):193-201. PMID: 21172210; PMCID: PMC3049955.
    116. Tobin MC, Moparty B, Farhadi A, DeMeo MT, Bansal PJ, Keshavarzian A. Atopic irritable bowel syndrome: a novel subgroup of irritable bowel syndrome with allergic manifestations. Ann Allergy Asthma Immunol. 2008 Jan; 100(1):49-53. PMID: 18254482.
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    117. Tang Y, Banan A, Forsyth CB, Fields JZ, Lau CK, Zhang LJ, Keshavarzian A. Effect of alcohol on miR-212 expression in intestinal epithelial cells and its potential role in alcoholic liver disease. Alcohol Clin Exp Res. 2008 Feb; 32(2):355-64. PMID: 18162065.
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    118. Ranjbaran Z, Keefer L, Farhadi A, Stepanski E, Sedghi S, Keshavarzian A. Impact of sleep disturbances in inflammatory bowel disease. J Gastroenterol Hepatol. 2007 Nov; 22(11):1748-53. PMID: 17914945.
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    119. Melson J, Jakate S, Fung H, Arai S, Keshavarzian A. Crypt loss is a marker of clinical severity of acute gastrointestinal graft-versus-host disease. Am J Hematol. 2007 Oct; 82(10):881-6. PMID: 17570511.
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    120. Keefer L, Keshavarzian A. Feasibility and acceptability of gut-directed hypnosis on inflammatory bowel disease: a brief communication. Int J Clin Exp Hypn. 2007 Oct; 55(4):457-66. PMID: 17786661.
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    121. Banan A, Keshavarzian A, Zhang L, Shaikh M, Forsyth CB, Tang Y, Fields JZ. NF-kappaB activation as a key mechanism in ethanol-induced disruption of the F-actin cytoskeleton and monolayer barrier integrity in intestinal epithelium. Alcohol. 2007 Sep; 41(6):447-60. PMID: 17869053.
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    122. Keshavarzian A, Mutlu E, Guzman JP, Forsyth C, Banan A. Phosphodiesterase 4 inhibitors and inflammatory bowel disease: emerging therapies in inflammatory bowel disease. Expert Opin Investig Drugs. 2007 Sep; 16(9):1489-506. PMID: 17714033.
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    123. Farhadi A, Keshavarzian A, Fields JZ, Jakate S, Shaikh M, Banan A. Reduced immunostaining for c-kit receptors in mucosal mast cells in inflammatory bowel disease. J Gastroenterol Hepatol. 2007 Dec; 22(12):2338-43. PMID: 17645464.
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    124. Farhadi A, Fields JZ, Keshavarzian A. Mucosal mast cells are pivotal elements in inflammatory bowel disease that connect the dots: stress, intestinal hyperpermeability and inflammation. World J Gastroenterol. 2007 Jun 14; 13(22):3027-30. PMID: 17589915; PMCID: PMC4172606.
    125. Cvetanovic I, Lin C, Ranade V, Keshavarzian A, Somberg J. The effects of quinidine and its chiral isolates on erg-1sm potassium current and correlation with gastrointestinal augmentation. Am J Ther. 2007 May-Jun; 14(3):269-76. PMID: 17515703.
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    126. Keshavarzian A, Mayer L, Salzberg B, Garone M, Finkelstein W, Cappa J, Brand M, Hain J, Zelinger D, Hegedus R, Diamond RH, Campbell U, Lane C, Stang P, Watson J, Cominelli F. A multicenter retrospective experience of infliximab in Crohn's disease patients: infusion reaction rates and treatment persistency. Gastroenterol Hepatol (N Y). 2007 May; 3(5):381-90. PMID: 21960854; PMCID: PMC3099319.
    127. Farhadi A, Forsyth C, Banan A, Shaikh M, Engen P, Fields JZ, Keshavarzian A. Evidence for non-chemical, non-electrical intercellular signaling in intestinal epithelial cells. Bioelectrochemistry. 2007 Nov; 71(2):142-8. PMID: 17428745.
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    128. Komanduri S, Gillevet PM, Sikaroodi M, Mutlu E, Keshavarzian A. Dysbiosis in pouchitis: evidence of unique microfloral patterns in pouch inflammation. Clin Gastroenterol Hepatol. 2007 Mar; 5(3):352-60. PMID: 17368235.
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    129. Haddish-Berhane N, Farhadi A, Nyquist C, Haghighi K, Keshavarzian A. Biological variability and targeted delivery of therapeutics for inflammatory bowel diseases: an in silico approach. Inflamm Allergy Drug Targets. 2007 Mar; 6(1):47-55. PMID: 17352688.
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    130. Ranjbaran Z, Keefer L, Stepanski E, Farhadi A, Keshavarzian A. The relevance of sleep abnormalities to chronic inflammatory conditions. Inflamm Res. 2007 Feb; 56(2):51-7. PMID: 17431741.
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    131. Rose DJ, DeMeo MT, Keshavarzian A, Hamaker BR. Influence of dietary fiber on inflammatory bowel disease and colon cancer: importance of fermentation pattern. Nutr Rev. 2007 Feb; 65(2):51-62. PMID: 17345958.
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    132. Forsyth CB, Banan A, Farhadi A, Fields JZ, Tang Y, Shaikh M, Zhang LJ, Engen PA, Keshavarzian A. Regulation of oxidant-induced intestinal permeability by metalloprotease-dependent epidermal growth factor receptor signaling. J Pharmacol Exp Ther. 2007 Apr; 321(1):84-97. PMID: 17220428.
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    133. Schreiber S, Keshavarzian A, Isaacs KL, Schollenberger J, Guzman JP, Orlandi C, Hanauer SB. A randomized, placebo-controlled, phase II study of tetomilast in active ulcerative colitis. Gastroenterology. 2007 Jan; 132(1):76-86. PMID: 17241861.
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    134. Keefer L, Stepanski EJ, Ranjbaran Z, Benson LM, Keshavarzian A. An initial report of sleep disturbance in inactive inflammatory bowel disease. J Clin Sleep Med. 2006 Oct 15; 2(4):409-16. PMID: 17557469.
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    135. Kaplan M, Mutlu EA, Benson M, Fields JZ, Banan A, Keshavarzian A. Use of herbal preparations in the treatment of oxidant-mediated inflammatory disorders. Complement Ther Med. 2007 Sep; 15(3):207-16. PMID: 17709066.
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    136. Fayad R, Brand MI, Stone D, Keshavarzian A, Qiao L. Apoptosis resistance in ulcerative colitis: high expression of decoy receptors by lamina propria T cells. Eur J Immunol. 2006 Aug; 36(8):2215-22. PMID: 16856205.
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    137. Mutlu EA, Keshavarzian A, Mutlu GM. Hyperalbuminemia and elevated transaminases associated with high-protein diet. Scand J Gastroenterol. 2006 Jun; 41(6):759-60. PMID: 16716979.
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    138. Farhadi A, Keshavarzian A, Fields JZ, Sheikh M, Banan A. Resolution of common dietary sugars from probe sugars for test of intestinal permeability using capillary column gas chromatography. J Chromatogr B Analyt Technol Biomed Life Sci. 2006 May 19; 836(1-2):63-8. PMID: 16621740.
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    139. Wessinger S, Kaplan M, Choi L, Williams M, Lau C, Sharp L, Crowell MD, Keshavarzian A, Jones MP. Increased use of selective serotonin reuptake inhibitors in patients admitted with gastrointestinal haemorrhage: a multicentre retrospective analysis. Aliment Pharmacol Ther. 2006 Apr 01; 23(7):937-44. PMID: 16573796.
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    140. Jakate S, Demeo M, John R, Tobin M, Keshavarzian A. Mastocytic enterocolitis: increased mucosal mast cells in chronic intractable diarrhea. Arch Pathol Lab Med. 2006 Mar; 130(3):362-7. PMID: 16519565.
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    141. Frantzides CT, Madan AK, Gupta PK, Smith C, Keshavarzian A. Laparoscopic repair of congenital duodenal obstruction. J Laparoendosc Adv Surg Tech A. 2006 Feb; 16(1):48-50. PMID: 16494548.
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    142. Haddish-Berhane N, Nyquist C, Haghighi K, Corvalan C, Keshavarzian A, Campanella O, Rickus J, Farhadi A. A multi-scale stochastic drug release model for polymer-coated targeted drug delivery systems. J Control Release. 2006 Jan 10; 110(2):314-22. PMID: 16288814.
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    143. Farhadi A, Keshavarzian A, Van de Kar LD, Jakate S, Domm A, Zhang L, Shaikh M, Banan A, Fields JZ. Heightened responses to stressors in patients with inflammatory bowel disease. Am J Gastroenterol. 2005 Aug; 100(8):1796-804. PMID: 16086717.
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    144. Farhadi A, Keshavarzian A, Ranjbaran Z, Fields JZ, Banan A. The role of protein kinase C isoforms in modulating injury and repair of the intestinal barrier. J Pharmacol Exp Ther. 2006 Jan; 316(1):1-7. PMID: 16002462.
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    145. Banan A, Zhang LJ, Shaikh M, Fields JZ, Choudhary S, Forsyth CB, Farhadi A, Keshavarzian A. theta Isoform of protein kinase C alters barrier function in intestinal epithelium through modulation of distinct claudin isotypes: a novel mechanism for regulation of permeability. J Pharmacol Exp Ther. 2005 Jun; 313(3):962-82. PMID: 15900076.
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    146. Ren JC, Banan A, Keshavarzian A, Zhu Q, Lapaglia N, McNulty J, Emanuele NV, Emanuele MA. Exposure to ethanol induces oxidative damage in the pituitary gland. Alcohol. 2005 Feb; 35(2):91-101. PMID: 15963422.
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    147. Frantzides CT, Carlson MA, Moore RE, Zografakis JG, Madan AK, Puumala S, Keshavarzian A. Effect of body mass index on nonalcoholic fatty liver disease in patients undergoing minimally invasive bariatric surgery. J Gastrointest Surg. 2004 Nov; 8(7):849-55. PMID: 15531238.
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    148. Cotler SJ, Kanji K, Keshavarzian A, Jensen DM, Jakate S. Prevalence and significance of autoantibodies in patients with non-alcoholic steatohepatitis. J Clin Gastroenterol. 2004 Oct; 38(9):801-4. PMID: 15365409.
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    149. Frantzides CT, Madan AK, Moore RE, Zografakis JG, Carlson MA, Keshavarzian A. Laparoscopic transgastric esophageal mucosal resection for high-grade dysplasia. J Laparoendosc Adv Surg Tech A. 2004 Oct; 14(5):261-5. PMID: 15630939.
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    150. Banan A, Zhang LJ, Farhadi A, Fields JZ, Shaikh M, Forsyth CB, Choudhary S, Keshavarzian A. Critical role of the atypical {lambda} isoform of protein kinase C (PKC-{lambda}) in oxidant-induced disruption of the microtubule cytoskeleton and barrier function of intestinal epithelium. J Pharmacol Exp Ther. 2005 Feb; 312(2):458-71. PMID: 15347733.
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    151. Banan A, Zhang LJ, Shaikh M, Fields JZ, Farhadi A, Keshavarzian A. Novel effect of NF-kappaB activation: carbonylation and nitration injury to cytoskeleton and disruption of monolayer barrier in intestinal epithelium. Am J Physiol Cell Physiol. 2004 Oct; 287(4):C1139-51. PMID: 15175222.
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    152. Banan A, Zhang LJ, Shaikh M, Fields JZ, Farhadi A, Keshavarzian A. Theta-isoform of PKC is required for alterations in cytoskeletal dynamics and barrier permeability in intestinal epithelium: a novel function for PKC-theta. Am J Physiol Cell Physiol. 2004 Jul; 287(1):C218-34. PMID: 14985240.
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    153. Banan A, Zhang LJ, Shaikh M, Fields JZ, Farhadi A, Keshavarzian A. Inhibition of oxidant-induced nuclear factor-kappaB activation and inhibitory-kappaBalpha degradation and instability of F-actin cytoskeletal dynamics and barrier function by epidermal growth factor: key role of phospholipase-gamma isoform. J Pharmacol Exp Ther. 2004 Apr; 309(1):356-68. PMID: 14724221.
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    154. Madan AK, Frantzides CT, Keshavarzian A, Smith C. Laparoscopic wedge resection of gastric leiomyoma. JSLS. 2004 Jan-Mar; 8(1):77-80. PMID: 14974670; PMCID: PMC3015518.
    155. Frantzides CT, Moore RE, Carlson MA, Madan AK, Zografakis JG, Keshavarzian A, Smith C. Minimally invasive surgery for achalasia: a 10-year experience. J Gastrointest Surg. 2004 Jan; 8(1):18-23. PMID: 14746831.
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    156. Banan A, Zhang LJ, Farhadi A, Fields JZ, Shaikh M, Keshavarzian A. PKC-beta1 isoform activation is required for EGF-induced NF-kappaB inactivation and IkappaBalpha stabilization and protection of F-actin assembly and barrier function in enterocyte monolayers. Am J Physiol Cell Physiol. 2004 Mar; 286(3):C723-38. PMID: 14602581.
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    157. Kaplan M, Mutlu EA, Jakate S, Bruninga K, Losurdo J, Losurdo J, Keshavarzian A. Endoscopy in eosinophilic esophagitis: "feline" esophagus and perforation risk. Clin Gastroenterol Hepatol. 2003 Nov; 1(6):433-7. PMID: 15017642.
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    158. Keshavarzian A, Fields J. Alcoholic liver disease: is it an "extraintestinal" complication of alcohol-induced intestinal injury? J Lab Clin Med. 2003 Nov; 142(5):285-7. PMID: 14647031.
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    159. Banan A, Fields JZ, Zhang LJ, Shaikh M, Farhadi A, Keshavarzian A. Zeta isoform of protein kinase C prevents oxidant-induced nuclear factor-kappaB activation and I-kappaBalpha degradation: a fundamental mechanism for epidermal growth factor protection of the microtubule cytoskeleton and intestinal barrier integrity. J Pharmacol Exp Ther. 2003 Oct; 307(1):53-66. PMID: 12893839.
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    160. Banan A, Farhadi A, Fields JZ, Mutlu E, Zhang L, Keshavarzian A. Evidence that nuclear factor-kappa B activation is critical in oxidant-induced disruption of the microtubule cytoskeleton and barrier integrity and that its inactivation is essential in epidermal growth factor-mediated protection of the monolayers of intestinal epithelia. J Pharmacol Exp Ther. 2003 Jul; 306(1):13-28. PMID: 12815011.
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    161. Banan A, Zhang LJ, Shaikh M, Fields JZ, Farhadi A, Keshavarzian A. Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly. Am J Physiol Cell Physiol. 2003 Oct; 285(4):C977-93. PMID: 12788694.
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    162. Farhadi A, Banan A, Fields J, Keshavarzian A. Intestinal barrier: an interface between health and disease. J Gastroenterol Hepatol. 2003 May; 18(5):479-97. PMID: 12702039.
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    163. Keshavarzian A, Banan A, Farhadi A, Komanduri S, Mutlu E, Zhang Y, Fields JZ. Increases in free radicals and cytoskeletal protein oxidation and nitration in the colon of patients with inflammatory bowel disease. Gut. 2003 May; 52(5):720-8. PMID: 12692059; PMCID: PMC1773652.
    164. Bhattacharya B, Jakate S, Saclarides TJ, Keshavarzian A. Gastric heterotopia presenting as a mass in jejunum. Arch Pathol Lab Med. 2003 Apr; 127(4):506-7. PMID: 12683890.
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    165. Banan A, Farhadi A, Fields JZ, Zhang LJ, Shaikh M, Keshavarzian A. The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide up-regulation: key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of intestinal epithelia. J Pharmacol Exp Ther. 2003 May; 305(2):482-94. PMID: 12606598.
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    166. Farhadi A, Keshavarzian A, Holmes EW, Fields J, Zhang L, Banan A. Gas chromatographic method for detection of urinary sucralose: application to the assessment of intestinal permeability. J Chromatogr B Analyt Technol Biomed Life Sci. 2003 Jan 25; 784(1):145-54. PMID: 12504193.
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    167. Banan A, Zhang L, Fields JZ, Farhadi A, Talmage DA, Keshavarzian A. PKC-zeta prevents oxidant-induced iNOS upregulation and protects the microtubules and gut barrier integrity. Am J Physiol Gastrointest Liver Physiol. 2002 Oct; 283(4):G909-22. PMID: 12223351.
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    168. Banan A, Fields JZ, Farhadi A, Talmage DA, Zhang L, Keshavarzian A. Activation of delta-isoform of protein kinase C is required for oxidant-induced disruption of both the microtubule cytoskeleton and permeability barrier of intestinal epithelia. J Pharmacol Exp Ther. 2002 Oct; 303(1):17-28. PMID: 12235228.
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    169. Alnadjim Z, Kayali Z, Haddad W, Holmes EW, Keshavarzian A, Mittal N, Ivancic D, Koehler R, Goldsmith D, Waltenbaugh C, Barrett TA. Differential effects of T-cell activation on gastric and small bowel permeability in alcohol-consuming mice. Alcohol Clin Exp Res. 2002 Sep; 26(9):1436-43. PMID: 12351940.
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    170. Komanduri S, Jakate S, Keshavarzian A. Focal rectal capillaritis: microscopic polyangiitis presenting as painless rectal bleeding. J Clin Gastroenterol. 2002 Aug; 35(2):157-9. PMID: 12172362.
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    171. Banan A, Fields JZ, Farhadi A, Talmage DA, Zhang L, Keshavarzian A. The beta 1 isoform of protein kinase C mediates the protective effects of epidermal growth factor on the dynamic assembly of F-actin cytoskeleton and normalization of calcium homeostasis in human colonic cells. J Pharmacol Exp Ther. 2002 Jun; 301(3):852-66. PMID: 12023512.
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    172. Farhadi A, Keshavarzian A, Fitzpatrick LR, Mutlu E, Zhang Y, Banan A. Modulatory effects of plasma and colonic milieu of patients with ulcerative colitis on neutrophil reactive oxygen species production in presence of a novel antioxidant, rebamipide. Dig Dis Sci. 2002 Jun; 47(6):1342-8. PMID: 12064811.
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    173. Banan A, Fields JZ, Talmage DA, Zhang L, Keshavarzian A. PKC-zeta is required in EGF protection of microtubules and intestinal barrier integrity against oxidant injury. Am J Physiol Gastrointest Liver Physiol. 2002 May; 282(5):G794-808. PMID: 11960776.
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    174. DeMeo MT, Mutlu EA, Keshavarzian A, Tobin MC. Intestinal permeation and gastrointestinal disease. J Clin Gastroenterol. 2002 Apr; 34(4):385-96. PMID: 11907349.
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    175. Mutlu EA, Farhadi A, Keshavarzian A. New developments in the treatment of inflammatory bowel disease. Expert Opin Investig Drugs. 2002 Mar; 11(3):365-85. PMID: 11866666.
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    176. Farhadi A, Fields J, Banan A, Keshavarzian A. Reactive oxygen species: are they involved in the pathogenesis of GERD, Barrett's esophagus, and the latter's progression toward esophageal cancer? Am J Gastroenterol. 2002 Jan; 97(1):22-6. PMID: 11808965.
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    177. Keshavarzian A, Choudhary S, Holmes EW, Yong S, Banan A, Jakate S, Fields JZ. Preventing gut leakiness by oats supplementation ameliorates alcohol-induced liver damage in rats. J Pharmacol Exp Ther. 2001 Nov; 299(2):442-8. PMID: 11602653.
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    178. Choudhary S, Keshavarzian A, Yong S, Wade M, Bocckino S, Day BJ, Banan A. Novel antioxidants zolimid and AEOL11201 ameliorate colitis in rats. Dig Dis Sci. 2001 Oct; 46(10):2222-30. PMID: 11680601.
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    179. Banan A, Fields JZ, Talmage DA, Zhang Y, Keshavarzian A. PKC-beta1 mediates EGF protection of microtubules and barrier of intestinal monolayers against oxidants. Am J Physiol Gastrointest Liver Physiol. 2001 Sep; 281(3):G833-47. PMID: 11518696.
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    180. Banan A, Fields JZ, Zhang Y, Keshavarzian A. Phospholipase C-gamma inhibition prevents EGF protection of intestinal cytoskeleton and barrier against oxidants. Am J Physiol Gastrointest Liver Physiol. 2001 Aug; 281(2):G412-23. PMID: 11447022.
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    181. Farhadi A, Bruninga K, Fields J, Keshavarzian A. Irritable bowel syndrome: an update on therapeutic modalities. Expert Opin Investig Drugs. 2001 Jul; 10(7):1211-22. PMID: 11772245.
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    182. Banan A, Fields JZ, Zhang Y, Keshavarzian A. iNOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers. Am J Physiol Gastrointest Liver Physiol. 2001 Jun; 280(6):G1234-46. PMID: 11352817.
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    183. Bu P, Keshavarzian A, Stone DD, Liu J, Le PT, Fisher S, Qiao L. Apoptosis: one of the mechanisms that maintains unresponsiveness of the intestinal mucosal immune system. J Immunol. 2001 May 15; 166(10):6399-403. PMID: 11342665.
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    184. Banan A, Fields JZ, Zhang Y, Keshavarzian A. Key role of PKC and Ca2+ in EGF protection of microtubules and intestinal barrier against oxidants. Am J Physiol Gastrointest Liver Physiol. 2001 May; 280(5):G828-43. PMID: 11292590.
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    185. Kennedy M, Bruninga K, Mutlu EA, Losurdo J, Choudhary S, Keshavarzian A. Successful and sustained treatment of chronic radiation proctitis with antioxidant vitamins E and C. Am J Gastroenterol. 2001 Apr; 96(4):1080-4. PMID: 11316150.
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    186. Banan A, Fitzpatrick L, Zhang Y, Keshavarzian A. OPC-compounds prevent oxidant-induced carbonylation and depolymerization of the F-actin cytoskeleton and intestinal barrier hyperpermeability. Free Radic Biol Med. 2001 Feb 01; 30(3):287-98. PMID: 11165875.
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    187. Mathurin P, Deng QG, Keshavarzian A, Choudhary S, Holmes EW, Tsukamoto H. Exacerbation of alcoholic liver injury by enteral endotoxin in rats. Hepatology. 2000 Nov; 32(5):1008-17. PMID: 11050051.
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    188. Banan A, Fields JZ, Decker H, Zhang Y, Keshavarzian A. Nitric oxide and its metabolites mediate ethanol-induced microtubule disruption and intestinal barrier dysfunction. J Pharmacol Exp Ther. 2000 Sep; 294(3):997-1008. PMID: 10945852.
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    189. Banan A, Zhang Y, Losurdo J, Keshavarzian A. Carbonylation and disassembly of the F-actin cytoskeleton in oxidant induced barrier dysfunction and its prevention by epidermal growth factor and transforming growth factor alpha in a human colonic cell line. Gut. 2000 Jun; 46(6):830-7. PMID: 10807896; PMCID: PMC1756435.
    190. Keshavarzian A, Fields J. Alcohol: "ice-breaker" yes, "gut barrier-breaker," maybe. Am J Gastroenterol. 2000 May; 95(5):1124-5. PMID: 10811316.
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    191. Banan A, Choudhary S, Zhang Y, Fields JZ, Keshavarzian A. Oxidant-induced intestinal barrier disruption and its prevention by growth factors in a human colonic cell line: role of the microtubule cytoskeleton. Free Radic Biol Med. 2000 Mar 01; 28(5):727-38. PMID: 10754268.
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    192. Banan A, Choudhary S, Zhang Y, Fields JZ, Keshavarzian A. Ethanol-induced barrier dysfunction and its prevention by growth factors in human intestinal monolayers: evidence for oxidative and cytoskeletal mechanisms. J Pharmacol Exp Ther. 1999 Dec; 291(3):1075-85. PMID: 10565827.
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    193. Keshavarzian A, Fusunyan RD, Jacyno M, Winship D, MacDermott RP, Sanderson IR. Increased interleukin-8 (IL-8) in rectal dialysate from patients with ulcerative colitis: evidence for a biological role for IL-8 in inflammation of the colon. Am J Gastroenterol. 1999 Mar; 94(3):704-12. PMID: 10086655.
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    194. Robinson CE, Keshavarzian A, Pasco DS, Frommel TO, Winship DH, Holmes EW. Determination of protein carbonyl groups by immunoblotting. Anal Biochem. 1999 Jan 01; 266(1):48-57. PMID: 9887212.
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    195. Keshavarzian A, Holmes EW, Patel M, Iber F, Fields JZ, Pethkar S. Leaky gut in alcoholic cirrhosis: a possible mechanism for alcohol-induced liver damage. Am J Gastroenterol. 1999 Jan; 94(1):200-7. PMID: 9934756.
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    196. Bruninga K, Riedy L, Keshavarzian A, Walter J. The effect of electrical stimulation on colonic transit following spinal cord injury in cats. Spinal Cord. 1998 Dec; 36(12):847-53. PMID: 9881734.
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    197. DeMeo M, Kolli S, Keshavarzian A, Borton M, Al-Hosni M, Dyavanapalli M, Shiau A, Tu N, Frommel T, Zarling E, Goris G, Shawaryn G, Mobarhan S. Beneficial effect of a bile acid resin binder on enteral feeding induced diarrhea. Am J Gastroenterol. 1998 Jun; 93(6):967-71. PMID: 9647030.
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    198. Holmes EW, Yong SL, Eiznhamer D, Keshavarzian A. Glutathione content of colonic mucosa: evidence for oxidative damage in active ulcerative colitis. Dig Dis Sci. 1998 May; 43(5):1088-95. PMID: 9590426.
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    199. Robinson CE, Kottapalli V, D'Astice M, Fields JZ, Winship D, Keshavarzian A. Regulation of neutrophils in ulcerative colitis by colonic factors: a possible mechanism of neutrophil activation and tissue damage. J Lab Clin Med. 1997 Dec; 130(6):590-602. PMID: 9422333.
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    200. Keshavarzian A, Haydek JM, Jacyno M, Holmes EW, Harford F. Modulatory effects of the colonic milieu on neutrophil oxidative burst: a possible pathogenic mechanism of ulcerative colitis. J Lab Clin Med. 1997 Aug; 130(2):216-25. PMID: 9280150.
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    201. Kristopaitis T, Neghme C, Yong SL, Chejfec G, Aranha G, Keshavarzian A. Giant antral ulcer: a rare presentation of eosinophilic gastroenteritis--case report and review of the literature. Am J Gastroenterol. 1997 Jul; 92(7):1205-8. PMID: 9219801.
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    202. Breuer RI, Soergel KH, Lashner BA, Christ ML, Hanauer SB, Vanagunas A, Harig JM, Keshavarzian A, Robinson M, Sellin JH, Weinberg D, Vidican DE, Flemal KL, Rademaker AW. Short chain fatty acid rectal irrigation for left-sided ulcerative colitis: a randomised, placebo controlled trial. Gut. 1997 Apr; 40(4):485-91. PMID: 9176076; PMCID: PMC1027123.
    203. Riedy L, Bruninga K, Keshavarzian A, Walter J. Placement of colonic manometric catheters and electrodes in cats. Lab Anim Sci. 1997 Feb; 47(1):78-81. PMID: 9051651.
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    204. Kazi N, Radvany R, Oldham T, Keshavarzian A, Frommel TO, Libertin C, Mobarhan S. Immunomodulatory effect of beta-carotene on T lymphocyte subsets in patients with resected colonic polyps and cancer. Nutr Cancer. 1997; 28(2):140-5. PMID: 9290119.
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    205. Ashrani A, Keshavarzian A, Jacyno M, Winship D, Fields JZ. Are dipyridamole (sensitive) calcium channels present in esophageal smooth muscle? Life Sci. 1997; 60(26):PL423-30. PMID: 9199491.
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    206. Pouderoux P, Friedman N, Shirazi P, Ringelstein JG, Keshavarzian A. Effect of carbonated water on gastric emptying and intragastric meal distribution. Dig Dis Sci. 1997 Jan; 42(1):34-9. PMID: 9009113.
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    207. Aranha GV, Walsh RM, Jacobs HK, Freeark RJ, Harford FJ, Keshavarzian A, Zarling EJ. Factors influencing bowel function following total abdominal colectomy. Dis Colon Rectum. 1996 Dec; 39(12):1418-22. PMID: 8969669.
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    208. Keshavarzian A, Jacyno M, Urban G, Winship D, Fields JZ. The role of nitric oxide in ethanol-induced gastrointestinal dysfunction. Alcohol Clin Exp Res. 1996 Dec; 20(9):1618-24. PMID: 8986213.
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    209. Zarif A, Eiznhamer D, Callaghan C, Doria MI, Broutman L, Keshavarzian A. The effect of a selective 5-lipoxygenase inhibitor, zileuton, on tissue damage in acute colonic inflammation in rats. Inflammation. 1996 Jun; 20(3):217-27. PMID: 8796377.
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    210. Figler TJ, Keshavarzian A, Nand S, Demos TC. Retroperitoneal amyloidosis, factor IX and X deficiency,and gastrointestinal bleeding. Abdom Imaging. 1996 May-Jun; 21(3):266-8. PMID: 8661563.
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    211. Patel M, Keshavarzian A, Kottapalli V, Badie B, Winship D, Fields JZ. Human neutrophil functions are inhibited in vitro by clinically relevant ethanol concentrations. Alcohol Clin Exp Res. 1996 Apr; 20(2):275-83. PMID: 8730218.
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    212. Keshavarzian A, Muska B, Sundaresan R, Urban G, Fields J. Ethanol at pharmacologically relevant concentrations inhibits contractility of isolated smooth muscle cells of cat esophagus. Alcohol Clin Exp Res. 1996 Feb; 20(1):180-4. PMID: 8651450.
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    213. Gaginella TS, Kachur JF, Tamai H, Keshavarzian A. Reactive oxygen and nitrogen metabolites as mediators of secretory diarrhea. Gastroenterology. 1995 Dec; 109(6):2019-28. PMID: 7498670.
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    214. Haydek JM, Keshavarzian A. Circulating neutrophils from patients with ulcerative colitis have a normal respiratory burst. Inflammation. 1995 Dec; 19(6):701-15. PMID: 8595936.
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    215. Fields JZ, Jacyno M, Wasyliw R, Winship D, Keshavarzian A. Ethanol inhibits contractility of esophageal smooth muscle strips. Alcohol Clin Exp Res. 1995 Dec; 19(6):1403-13. PMID: 8749802.
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    216. Miles AM, Owens MW, Milligan S, Johnson GG, Fields JZ, Ing TS, Kottapalli V, Keshavarzian A, Grisham MB. Nitric oxide synthase in circulating vs. extravasated polymorphonuclear leukocytes. J Leukoc Biol. 1995 Nov; 58(5):616-22. PMID: 7595064.
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    217. Olyaee M, Sontag S, Salman W, Schnell T, Mobarhan S, Eiznhamer D, Keshavarzian A. Mucosal reactive oxygen species production in oesophagitis and Barrett's oesophagus. Gut. 1995 Aug; 37(2):168-73. PMID: 7557561; PMCID: PMC1382711.
    218. Keshavarzian A, Barnes WE, Bruninga K, Nemchausky B, Mermall H, Bushnell D. Delayed colonic transit in spinal cord-injured patients measured by indium-111 Amberlite scintigraphy. Am J Gastroenterol. 1995 Aug; 90(8):1295-300. PMID: 7639233.
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    219. Kazi N, Fields JZ, Sedghi S, Kottapalli V, Eiznhamer D, Winship D, Keshavarzian A. Modulation of neutrophil function by novel colonic factors: possible role in the pathophysiology of ulcerative colitis. J Lab Clin Med. 1995 Jul; 126(1):70-80. PMID: 7602238.
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    220. Kachur JF, Keshavarzian A, Sundaresan R, Doria M, Walsh R, de las Alas MM, Gaginella TS. Colitis reduces short-circuit current response to inflammatory mediators in rat colonic mucosa. Inflammation. 1995 Apr; 19(2):245-59. PMID: 7541393.
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    221. Keshavarzian A, Fields JZ. A radical perspective on ulcerative colitis. J Gastroenterol Hepatol. 1995 Mar-Apr; 10(2):208-9. PMID: 7787169.
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    222. Keshavarzian A, Fields JZ, Vaeth J, Holmes EW. The differing effects of acute and chronic alcohol on gastric and intestinal permeability. Am J Gastroenterol. 1994 Dec; 89(12):2205-11. PMID: 7977243.
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    223. Sedghi S, Keshavarzian A, Klamut M, Eiznhamer D, Zarling EJ. Elevated breath ethane levels in active ulcerative colitis: evidence for excessive lipid peroxidation. Am J Gastroenterol. 1994 Dec; 89(12):2217-21. PMID: 7977245.
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    224. Keshavarzian A, Zorub O, Sayeed M, Urban G, Sweeney C, Winship D, Fields J. Acute ethanol inhibits calcium influxes into esophageal smooth but not striated muscle: a possible mechanism for ethanol-induced inhibition of esophageal contractility. J Pharmacol Exp Ther. 1994 Sep; 270(3):1057-62. PMID: 7932153.
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    225. Firouzi M, Keshavarzian A. Guillain-Barre syndrome and achalasia: two manifestations of a viral disease or coincidental association? Am J Gastroenterol. 1994 Sep; 89(9):1585-7. PMID: 8079948.
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    226. Fields JZ, Turk A, Durkin M, Ravi NV, Keshavarzian A. Increased gastrointestinal symptoms in chronic alcoholics. Am J Gastroenterol. 1994 Mar; 89(3):382-6. PMID: 8122650.
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    227. Keshavarzian A, Rentsch R, Hodgson HJ. Clinical implications of liver biopsy findings in collagen-vascular disorders. J Clin Gastroenterol. 1993 Oct; 17(3):219-26. PMID: 8228083.
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    228. Sedghi S, Fields JZ, Klamut M, Urban G, Durkin M, Winship D, Fretland D, Olyaee M, Keshavarzian A. Increased production of luminol enhanced chemiluminescence by the inflamed colonic mucosa in patients with ulcerative colitis. Gut. 1993 Sep; 34(9):1191-7. PMID: 8406152; PMCID: PMC1375452.
    229. Stinneford JG, Keshavarzian A, Nemchausky BA, Doria MI, Durkin M. Esophagitis and esophageal motor abnormalities in patients with chronic spinal cord injuries. Paraplegia. 1993 Jun; 31(6):384-92. PMID: 8337002.
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    230. Steck TB, Durkin MG, Costanzo-Nordin MR, Keshavarzian A. Gastrointestinal complications and endoscopic findings in heart transplant patients. J Heart Lung Transplant. 1993 Mar-Apr; 12(2):244-51. PMID: 8476897.
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    231. Keshavarzian A, Isaac RM. Erythromycin accelerates gastric emptying of indigestible solids and transpyloric migration of the tip of an enteral feeding tube in fasting and fed states. Am J Gastroenterol. 1993 Feb; 88(2):193-7. PMID: 8424419.
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    232. Keshavarzian A, Olyaee M, Sontag S, Mobarhan S. Increased levels of luminol-enhanced chemiluminescence by rectal mucosa of patients with colonic neoplasia: a possible marker for colonic neoplasia. Nutr Cancer. 1993; 19(2):201-6. PMID: 8502590.
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    233. Keshavarzian A, Haydek J, Zabihi R, Doria M, D'Astice M, Sorenson JR. Agents capable of eliminating reactive oxygen species. Catalase, WR-2721, or Cu(II)2(3,5-DIPS)4 decrease experimental colitis. Dig Dis Sci. 1992 Dec; 37(12):1866-73. PMID: 1335406.
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    234. Keshavarzian A, Doria MI, Sedghi S, Kanofsky JR, Hecht D, Holmes EW, Ibrahim C, List T, Urban G, Gaginella T, et al. Mitomycin C-induced colitis in rats: a new animal model of acute colonic inflammation implicating reactive oxygen species. J Lab Clin Med. 1992 Nov; 120(5):778-91. PMID: 1431507.
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    235. Keshavarzian A, Sedghi S, Kanofsky J, List T, Robinson C, Ibrahim C, Winship D. Excessive production of reactive oxygen metabolites by inflamed colon: analysis by chemiluminescence probe. Gastroenterology. 1992 Jul; 103(1):177-85. PMID: 1612325.
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    236. Keshavarzian A, Polepalle C, Iber FL, Durkin M. Secondary esophageal contractions are abnormal in chronic alcoholics. Dig Dis Sci. 1992 Apr; 37(4):517-22. PMID: 1551339.
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    237. Keshavarzian A, Gordon JH, Willson C, Urban G, Fields JZ. Chronic ethanol feeding produces a muscarinic receptor upregulation, but not a muscarinic supersensitivity in lower esophageal sphincter muscle. J Pharmacol Exp Ther. 1992 Feb; 260(2):601-7. PMID: 1346638.
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    238. Klamut MJ, Keshavarzian A. Stress ulcer. J Assoc Acad Minor Phys. 1992; 3(3):89-94. PMID: 1498526.
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    239. Keshavarzian A, Zapeda D, List T, Mobarhan S. High levels of reactive oxygen metabolites in colon cancer tissue: analysis by chemiluminescence probe. Nutr Cancer. 1992; 17(3):243-9. PMID: 1331990.
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    240. Steck TB, Costanzo-Nordin MR, Keshavarzian A. Prevalence and management of cholelithiasis in heart transplant patients. J Heart Lung Transplant. 1991 Nov-Dec; 10(6):1029-32. PMID: 1756150.
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    241. Keshavarzian A, Bushnell DL, Sontag S, Yegelwel EJ, Smid K. Gastric emptying in patients with severe reflux esophagitis. Am J Gastroenterol. 1991 Jun; 86(6):738-42. PMID: 2038997.
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    242. Keshavarzian A, Urban G, Sedghi S, Willson C, Sabella L, Sweeny C, Anderson K. Effect of acute ethanol on esophageal motility in cat. Alcohol Clin Exp Res. 1991 Feb; 15(1):116-21. PMID: 2024723.
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    243. Keshavarzian A, Haydek JM, Zepeda DO, Stinneford JG, Fields JZ. Gastroduodenal ulcers in rats induced by 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP): requirement for gastric acid secretion and the role of prostaglandins. Res Commun Chem Pathol Pharmacol. 1990 Oct; 70(1):21-48. PMID: 2124715.
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    244. Keshavarzian A, Polepalle C, Iber FL, Durkin M. Esophageal motor disorder in alcoholics: result of alcoholism or withdrawal? Alcohol Clin Exp Res. 1990 Aug; 14(4):561-7. PMID: 2221284.
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    245. Keshavarzian A, Morgan G, Sedghi S, Gordon JH, Doria M. Role of reactive oxygen metabolites in experimental colitis. Gut. 1990 Jul; 31(7):786-90. PMID: 2164491; PMCID: PMC1378536.
    246. Berger SA, Keshavarzian A, DeMeo MT, Mobarhan S. Erythromycin in chronic intestinal pseudo-obstruction. J Clin Gastroenterol. 1990 Jun; 12(3):363. PMID: 2362109.
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    247. Willson CA, Bushnell D, Keshavarzian A. The effect of acute and chronic ethanol administration on gastric emptying in cats. Dig Dis Sci. 1990 Apr; 35(4):444-8. PMID: 2318090.
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    248. Keshavarzian A, Steck TB, Conway D, Gordon JH, Fields JZ. Canine gastric muscarinic receptors up-regulate after vagotomy. Dig Dis Sci. 1990 Apr; 35(4):449-52. PMID: 2318091.
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    249. Keshavarzian A, Wibowo A, Gordon JH, Fields JZ. MPTP-induced duodenal ulcers in rat. Prevention by reuptake blockers for serotonin and norepinephrine, but not dopamine. Gastroenterology. 1990 Mar; 98(3):554-60. PMID: 2298362.
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    250. Keshavarzian A, Rizk G, Urban G, Willson C. Ethanol-induced esophageal motor disorder: development of an animal model. Alcohol Clin Exp Res. 1990 Feb; 14(1):76-81. PMID: 2178477.
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    251. Posniak HV, Keshavarzian A, Jabamoni R. Diaphragmatic endometriosis: CT and MR findings. Gastrointest Radiol. 1990; 15(4):349-51. PMID: 2210213.
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    252. Keshavarzian A, Schoenau G, Isaac R. Percutaneous endoscopic gastrostomy tube placement in cats. Lab Anim Sci. 1989 Sep; 39(5):459-61. PMID: 2811293.
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    253. Yegelwel EJ, Bushnell DL, Fisher SG, Keshavarzian A. Technetium pertechnetate esophageal imaging for detection of Barrett's esophagus. Dig Dis Sci. 1989 Jul; 34(7):1075-8. PMID: 2545424.
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    254. Keshavarzian A, Dutta SK. Carbohydrate malabsorption in alcoholic pancreatic insufficiency. The effect of pancreatic enzyme therapy on intestinal transit time. J Clin Gastroenterol. 1988 Oct; 10(5):528-32. PMID: 2460519.
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    255. Chadwick VS, Mellor DM, Myers DB, Selden AC, Keshavarzian A, Broom MF, Hobson CH. Production of peptides inducing chemotaxis and lysosomal enzyme release in human neutrophils by intestinal bacteria in vitro and in vivo. Scand J Gastroenterol. 1988 Jan; 23(1):121-8. PMID: 3278364.
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    256. Keshavarzian A, Iber FL. Gastrointestinal involvement in insulin-requiring diabetes mellitus. J Clin Gastroenterol. 1987 Dec; 9(6):685-92. PMID: 3443733.
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    257. Keshavarzian A, Dunne M, Iber FL. Gallbladder volume and emptying in insulin-requiring male diabetics. Dig Dis Sci. 1987 Aug; 32(8):824-8. PMID: 3301231.
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    258. Keshavarzian A, Iber FL, Nasrallah S. Radionuclide esophageal emptying and manometric studies in diabetes mellitus. Am J Gastroenterol. 1987 Jul; 82(7):625-31. PMID: 3605023.
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    259. Keshavarzian A, Sladen GE, Isaacs PE. Selection of patients for jejunal biopsy. Dig Dis Sci. 1987 Jun; 32(6):669. PMID: 3568955.
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    260. Keshavarzian A, Iber FL, Ferguson Y. Esophageal manometry and radionuclide emptying in chronic alcoholics. Gastroenterology. 1987 Mar; 92(3):651-7. PMID: 3817388.
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    261. Gupta S, Walker DL, Keshavarzian A, Hodgson HJ. Upper endoscopy for occult bleeding in renal failure. J Clin Gastroenterol. 1987 Feb; 9(1):43-5. PMID: 3559112.
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    262. Keshavarzian A, Iber FL, Vaeth J. Gastric emptying in patients with insulin-requiring diabetes mellitus. Am J Gastroenterol. 1987 Jan; 82(1):29-35. PMID: 3799578.
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    263. Keshavarzian A, Iber FL, Greer P, Wobbleton J. Gastric emptying of solid meal in male chronic alcoholics. Alcohol Clin Exp Res. 1986 Aug; 10(4):432-5. PMID: 3530022.
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    264. Keshavarzian A, Iber FL, Dangleis MD, Cornish R. Intestinal-transit and lactose intolerance in chronic alcoholics. Am J Clin Nutr. 1986 Jul; 44(1):70-6. PMID: 3728351.
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    265. Keshavarzian A, Gupta S, Saverymuttu SH, Hodgson HJ. Are there ethnic differences in inflammatory bowel disease? Indian J Gastroenterol. 1986 Apr; 5(2):95-7. PMID: 3699862.
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    266. Keshavarzian A, Iber FL. Intestinal transit in insulin-requiring diabetics. Am J Gastroenterol. 1986 Apr; 81(4):257-60. PMID: 3962951.
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    267. Keshavarzian A, Gibson R, Guest J, Spencer J, Lavender JP, Hodgson HJ. Granulocyte migration in uncomplicated intestinal anastomosis in man. Dig Dis Sci. 1986 Mar; 31(3):268-72. PMID: 3948630.
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    268. Saverymuttu SH, Gupta S, Keshavarzian A, Donovan B, Hodgson HJ. Effect of a slow-release 5'-aminosalicylic acid preparation on disease activity in Crohn's disease. Digestion. 1986; 33(2):89-91. PMID: 3512352.
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    269. Isaacs JD, Keshavarzian A, Blumgart LH, Hodgson HJ. Juvenile chronic pancreatitis--a cause of painless jaundice in a patient with multiple somatic abnormalities. J Clin Gastroenterol. 1985 Dec; 7(6):533-6. PMID: 4086750.
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    270. Keshavarzian A, Price YE, Peters AM, Lavender JP, Wright NA, Hodgson HJ. Specificity of indium-111 granulocyte scanning and fecal excretion measurement in inflammatory bowel disease--an autoradiographic study. Dig Dis Sci. 1985 Dec; 30(12):1156-60. PMID: 4064866.
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    271. Gupta S, Saverymuttu SH, Keshavarzian A, Hodgson HJ. Is the pattern of inflammatory bowel disease different in the elderly? Age Ageing. 1985 Nov; 14(6):366-70. PMID: 4072825.
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    272. Saverymuttu SH, Keshavarzian A, Gibson R, Chadwick VS, Hodgson HJ. Hepatic abscesses associated with Crohn's disease detected by 111Indium leucocyte scanning. J Clin Gastroenterol. 1985 Jun; 7(3):273-6. PMID: 4020088.
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    273. Keshavarzian A, Saverymuttu SH, Tai PC, Thompson M, Barter S, Spry CJ, Chadwick VS. Activated eosinophils in familial eosinophilic gastroenteritis. Gastroenterology. 1985 Apr; 88(4):1041-9. PMID: 3918913.
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    274. Keshavarzian A, Meek J, Sutton C, Emery VM, Hughes EA, Hodgson HJ. Dietary protein supplementation from vegetable sources in the management of chronic portal systemic encephalopathy. Am J Gastroenterol. 1984 Dec; 79(12):945-9. PMID: 6391154.
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    275. Keshavarzian A, Saverymuttu SH, Chadwick VS, Lavender JP, Hodgson HJ. Noninvasive investigation of the gastrointestinal tract in collagen-vascular disease. Am J Gastroenterol. 1984 Nov; 79(11):873-7. PMID: 6507410.
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    276. Keshavarzian A, Saverymuttu SH, Chadwick VS. 111Indium leucocyte scanning in ampicillin-associated right-sided hemorrhagic colitis. Am J Gastroenterol. 1984 Jul; 79(7):541-2. PMID: 6611087.
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    277. Keshavarzian A, Isaacs P, McColl I, Sladen GE. Idiopathic intestinal pseudo-obstruction and contaminated small bowel syndrome--treatment with metronidazole, ileostomy, and indomethacin. Am J Gastroenterol. 1983 Sep; 78(9):562-5. PMID: 6688501.
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