 Up-Regulation
"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
| Descriptor ID |
D015854
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| MeSH Number(s) |
G02.111.087.880 G02.149.115.880 G05.355.315.850 G07.690.812.925 G07.700.680.925
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| Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
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Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 2 | 2 | 4 | | 2001 | 1 | 5 | 6 | | 2002 | 0 | 2 | 2 | | 2003 | 1 | 7 | 8 | | 2004 | 0 | 4 | 4 | | 2005 | 2 | 3 | 5 | | 2006 | 1 | 8 | 9 | | 2007 | 1 | 10 | 11 | | 2008 | 1 | 9 | 10 | | 2009 | 1 | 5 | 6 | | 2010 | 0 | 5 | 5 | | 2011 | 3 | 4 | 7 | | 2012 | 3 | 6 | 9 | | 2013 | 3 | 5 | 8 | | 2014 | 2 | 6 | 8 | | 2015 | 1 | 9 | 10 | | 2016 | 1 | 4 | 5 | | 2017 | 0 | 3 | 3 | | 2018 | 1 | 3 | 4 | | 2019 | 2 | 8 | 10 | | 2020 | 2 | 2 | 4 | | 2021 | 1 | 4 | 5 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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Ruge M, Gomez JMD, du Fay de Lavallaz J, Hlepas A, Rahman A, Patel P, Lavani P, Nair GG, Jahan N, Simmons JA, Rao AK, Williams KA, Volgman AS, Marinescu K, Suboc T. The prognostic value of cardiac troponin for 60 day mortality and major adverse events in COVID-19 patients. Cardiovasc Pathol. 2021 Nov-Dec; 55:107374.
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Zalocusky KA, Najm R, Taubes AL, Hao Y, Yoon SY, Koutsodendris N, Nelson MR, Rao A, Bennett DA, Bant J, Amornkul DJ, Xu Q, An A, Cisne-Thomson O, Huang Y. Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease. Nat Neurosci. 2021 06; 24(6):786-798.
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Qin S, Predescu D, Carman B, Patel P, Chen J, Kim M, Lahm T, Geraci M, Predescu SA. Up-Regulation of the Long Noncoding RNA X-Inactive-Specific Transcript and the Sex Bias in Pulmonary Arterial Hypertension. Am J Pathol. 2021 06; 191(6):1135-1150.
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Mazzotta C, Basu S, Gower AC, Karki S, Farb MG, Sroczynski E, Zizza E, Sarhan A, Pande AN, Walsh K, Dobrilovic N, Gokce N. Perivascular Adipose Tissue Inflammation in Ischemic Heart Disease. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1239-1250.
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Liu Y, Fan L, Cheng Z, Yu L, Cong S, Hu Y, Zhu L, Zhang B, Cheng Y, Zhao P, Zhao X, Cheng M. Fecal transplantation alleviates acute liver injury in mice through regulating Treg/Th17 cytokines balance. Sci Rep. 2021 01 15; 11(1):1611.
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Yao J, Sun B, Institoris A, Zhan X, Guo W, Song Z, Liu Y, Hiess F, Boyce AKJ, Ni M, Wang R, Ter Keurs H, Back TG, Fill M, Thompson RJ, Turner RW, Gordon GR, Chen SRW. Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not ß-Amyloid Accumulation. Cell Rep. 2020 09 22; 32(12):108169.
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Patel D, Roy A, Raha S, Kundu M, Gonzalez FJ, Pahan K. Upregulation of BDNF and hippocampal functions by a hippocampal ligand of PPARa. JCI Insight. 2020 05 21; 5(10).
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Zhang XZ, Luo DX, Bai XH, Ding HH, Liu M, Deng J, Mai JW, Yang YL, Zhang SB, Ruan XC, Zhang XQ, Xin WJ, Xu T. Upregulation of TRPC6 Mediated by PAX6 Hypomethylation Is Involved in the Mechanical Allodynia Induced by Chemotherapeutics in Dorsal Root Ganglion. Int J Neuropsychopharmacol. 2020 04 23; 23(4):257-267.
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Li J, Zhang B, Liu WX, Lu K, Pan H, Wang T, Oh CD, Yi D, Huang J, Zhao L, Ning G, Xing C, Xiao G, Liu-Bryan R, Feng S, Chen D. Metformin limits osteoarthritis development and progression through activation of AMPK signalling. Ann Rheum Dis. 2020 05; 79(5):635-645.
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Werneck-de-Castro JP, Blandino-Rosano M, Hilfiker-Kleiner D, Bernal-Mizrachi E. Glucose stimulates microRNA-199 expression in murine pancreatic ß-cells. J Biol Chem. 2020 01 31; 295(5):1261-1270.
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