 Up-Regulation
"Up-Regulation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A positive regulatory effect on physiological processes at the molecular, cellular, or systemic level. At the molecular level, the major regulatory sites include membrane receptors, genes (GENE EXPRESSION REGULATION), mRNAs (RNA, MESSENGER), and proteins.
| Descriptor ID |
D015854
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| MeSH Number(s) |
G02.111.087.880 G02.149.115.880 G05.355.315.850 G07.690.812.925 G07.700.680.925
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| Concept/Terms |
Up-Regulation- Up-Regulation
- Up Regulation
- Upregulation
- Up-Regulation (Physiology)
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Below are MeSH descriptors whose meaning is more general than "Up-Regulation".
Below are MeSH descriptors whose meaning is more specific than "Up-Regulation".
This graph shows the total number of publications written about "Up-Regulation" by people in this website by year, and whether "Up-Regulation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 0 | 1 | | 1992 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 2 | 2 | 4 | | 2001 | 1 | 5 | 6 | | 2002 | 0 | 2 | 2 | | 2003 | 1 | 7 | 8 | | 2004 | 0 | 4 | 4 | | 2005 | 2 | 3 | 5 | | 2006 | 1 | 8 | 9 | | 2007 | 1 | 10 | 11 | | 2008 | 1 | 9 | 10 | | 2009 | 1 | 5 | 6 | | 2010 | 0 | 4 | 4 | | 2011 | 3 | 4 | 7 | | 2012 | 3 | 5 | 8 | | 2013 | 3 | 5 | 8 | | 2014 | 2 | 6 | 8 | | 2015 | 1 | 9 | 10 | | 2016 | 1 | 4 | 5 | | 2017 | 0 | 3 | 3 | | 2018 | 1 | 3 | 4 | | 2019 | 2 | 8 | 10 | | 2020 | 2 | 1 | 3 | | 2021 | 3 | 8 | 11 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Up-Regulation" by people in Profiles.
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Kundu M, Raha S, Roy A, Pahan K. Regression of Triple-Negative Breast Cancer in a Patient-Derived Xenograft Mouse Model by Monoclonal Antibodies against IL-12 p40 Monomer. Cells. 2022 01 13; 11(2).
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Cong S, Liu Y, Li Y, Chen Y, Chen R, Zhang B, Yu L, Hu Y, Zhao X, Mu M, Cheng M, Huang Z. MiR-571 affects the development and progression of liver fibrosis by regulating the Notch3 pathway. Sci Rep. 2021 11 08; 11(1):21854.
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Ruge M, Gomez JMD, du Fay de Lavallaz J, Hlepas A, Rahman A, Patel P, Lavani P, Nair GG, Jahan N, Simmons JA, Rao AK, Williams KA, Volgman AS, Marinescu K, Suboc T. The prognostic value of cardiac troponin for 60 day mortality and major adverse events in COVID-19 patients. Cardiovasc Pathol. 2021 Nov-Dec; 55:107374.
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Zalocusky KA, Najm R, Taubes AL, Hao Y, Yoon SY, Koutsodendris N, Nelson MR, Rao A, Bennett DA, Bant J, Amornkul DJ, Xu Q, An A, Cisne-Thomson O, Huang Y. Neuronal ApoE upregulates MHC-I expression to drive selective neurodegeneration in Alzheimer's disease. Nat Neurosci. 2021 06; 24(6):786-798.
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Qin S, Predescu D, Carman B, Patel P, Chen J, Kim M, Lahm T, Geraci M, Predescu SA. Up-Regulation of the Long Noncoding RNA X-Inactive-Specific Transcript and the Sex Bias in Pulmonary Arterial Hypertension. Am J Pathol. 2021 06; 191(6):1135-1150.
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Arif M, Alam P, Ahmed RP, Pandey R, Faridi HM, Sadayappan S. Upregulated Angiogenesis Is Incompetent to Rescue Dilated Cardiomyopathy Phenotype in Mice. Cells. 2021 03 31; 10(4).
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Feng J, Zong P, Yan J, Yue Z, Li X, Smith C, Ai X, Yue L. Upregulation of transient receptor potential melastatin 4 (TRPM4) in ventricular fibroblasts from heart failure patients. Pflugers Arch. 2021 03; 473(3):521-531.
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Mazzotta C, Basu S, Gower AC, Karki S, Farb MG, Sroczynski E, Zizza E, Sarhan A, Pande AN, Walsh K, Dobrilovic N, Gokce N. Perivascular Adipose Tissue Inflammation in Ischemic Heart Disease. Arterioscler Thromb Vasc Biol. 2021 03; 41(3):1239-1250.
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Werneck-de-Castro JP, Peçanha FLM, Silvestre DH, Bernal-Mizrachi E. The RNA-binding protein LARP1 is dispensable for pancreatic ß-cell function and mass. Sci Rep. 2021 01 22; 11(1):2079.
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Liu Y, Fan L, Cheng Z, Yu L, Cong S, Hu Y, Zhu L, Zhang B, Cheng Y, Zhao P, Zhao X, Cheng M. Fecal transplantation alleviates acute liver injury in mice through regulating Treg/Th17 cytokines balance. Sci Rep. 2021 01 15; 11(1):1611.
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