 Calcium Signaling
"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
| Descriptor ID |
D020013
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| MeSH Number(s) |
G02.111.087.800.800.100 G02.149.115.800.800.100 G03.495.166.500.100 G04.299.880.800.100
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| Concept/Terms |
Calcium Signaling- Calcium Signaling
- Calcium Signalings
- Signaling, Calcium
- Signalings, Calcium
Calcium Waves- Calcium Waves
- Calcium Wave
- Wave, Calcium
- Waves, Calcium
- Calcium Oscillations
- Calcium Oscillation
- Oscillation, Calcium
- Oscillations, Calcium
Calcium Spikes- Calcium Spikes
- Calcium Spike
- Spike, Calcium
- Spikes, Calcium
Calcium Puffs- Calcium Puffs
- Calcium Puff
- Puff, Calcium
- Puffs, Calcium
Calcium Sparks- Calcium Sparks
- Calcium Spark
- Spark, Calcium
- Sparks, Calcium
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Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".
Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".
This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 3 | 1 | 4 | | 2003 | 2 | 4 | 6 | | 2004 | 4 | 3 | 7 | | 2005 | 6 | 1 | 7 | | 2006 | 9 | 2 | 11 | | 2007 | 8 | 3 | 11 | | 2008 | 7 | 2 | 9 | | 2009 | 8 | 0 | 8 | | 2010 | 5 | 1 | 6 | | 2011 | 2 | 2 | 4 | | 2012 | 4 | 1 | 5 | | 2013 | 9 | 4 | 13 | | 2014 | 4 | 2 | 6 | | 2015 | 3 | 0 | 3 | | 2016 | 3 | 2 | 5 | | 2017 | 6 | 5 | 11 | | 2018 | 1 | 2 | 3 | | 2019 | 1 | 1 | 2 | | 2020 | 4 | 0 | 4 | | 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Calcium Signaling" by people in Profiles.
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Yin L, Zahradnikova A, Rizzetto R, Boncompagni S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marqués-Sulé E, Aguilar-Sánchez Y, Fernández-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, Gerbaud P, Lai FA, Perrier R, Álvarez JL, Niggli E, Valdivia HH, Valdivia CR, Ramos-Franco J, Zorio E, Zissimopoulos S, Protasi F, Benitah JP, Gómez AM. Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation. Circ Res. 2021 07 23; 129(3):e35-e52.
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Bare DJ, Yue L, Ai X. A special issue on calcium dynamics of the heart: remodeling of ion channels and regulatory pathways. Pflugers Arch. 2021 03; 473(3):313-316.
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McKee C, Bare DJ, Ai X. Stress-driven cardiac calcium mishandling via a kinase-to-kinase crosstalk. Pflugers Arch. 2021 03; 473(3):363-375.
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Yan J, Bare DJ, DeSantiago J, Zhao W, Mei Y, Chen Z, Ginsburg K, Solaro RJ, Wolska BM, Bers DM, Chen SRW, Ai X. JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship. Circ Res. 2021 02 19; 128(4):455-470.
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Oropeza-Almazán Y, Blatter LA. Mitochondrial calcium uniporter complex activation protects against calcium alternans in atrial myocytes. Am J Physiol Heart Circ Physiol. 2020 10 01; 319(4):H873-H881.
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Gussak G, Marszalec W, Yoo S, Modi R, O'Callaghan C, Aistrup GL, Cordeiro JM, Goodrow R, Kanaporis G, Blatter LA, Shiferaw Y, Arora R, Zhou J, Burrell AR, Wasserstrom JA. Triggered Ca2+ Waves Induce Depolarization of Maximum Diastolic Potential and Action Potential Prolongation in Dog Atrial Myocytes. Circ Arrhythm Electrophysiol. 2020 06; 13(6):e008179.
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Martinez-Hernandez E, Blatter LA. Effect of carvedilol on atrial excitation-contraction coupling, Ca2+ release, and arrhythmogenicity. Am J Physiol Heart Circ Physiol. 2020 05 01; 318(5):H1245-H1255.
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Søndergaard MT, Liu Y, Brohus M, Guo W, Nani A, Carvajal C, Fill M, Overgaard MT, Chen SRW. Diminished inhibition and facilitated activation of RyR2-mediated Ca2+ release is a common defect of arrhythmogenic calmodulin mutations. FEBS J. 2019 11; 286(22):4554-4578.
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Treinys R, Kanaporis G, Fischmeister R, Jurevicius J. Metabolic Inhibition Induces Transient Increase of L-type Ca2+ Current in Human and Rat Cardiac Myocytes. Int J Mol Sci. 2019 Mar 26; 20(6).
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Kanaporis G, Kalik ZM, Blatter LA. Action potential shortening rescues atrial calcium alternans. J Physiol. 2019 02; 597(3):723-740.
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