 Calcium Signaling
"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
| Descriptor ID |
D020013
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| MeSH Number(s) |
G02.111.087.800.800.100 G02.149.115.800.800.100 G03.495.166.500.100 G04.299.880.800.100
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| Concept/Terms |
Calcium Signaling- Calcium Signaling
- Calcium Signalings
- Signaling, Calcium
- Signalings, Calcium
Calcium Waves- Calcium Waves
- Calcium Wave
- Wave, Calcium
- Waves, Calcium
- Calcium Oscillations
- Calcium Oscillation
- Oscillation, Calcium
- Oscillations, Calcium
Calcium Spikes- Calcium Spikes
- Calcium Spike
- Spike, Calcium
- Spikes, Calcium
Calcium Puffs- Calcium Puffs
- Calcium Puff
- Puff, Calcium
- Puffs, Calcium
Calcium Sparks- Calcium Sparks
- Calcium Spark
- Spark, Calcium
- Sparks, Calcium
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Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".
Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".
This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 3 | 1 | 4 | | 2003 | 1 | 4 | 5 | | 2004 | 4 | 2 | 6 | | 2005 | 5 | 1 | 6 | | 2006 | 9 | 2 | 11 | | 2007 | 8 | 3 | 11 | | 2008 | 7 | 2 | 9 | | 2009 | 8 | 0 | 8 | | 2010 | 5 | 1 | 6 | | 2011 | 2 | 2 | 4 | | 2012 | 4 | 1 | 5 | | 2013 | 9 | 4 | 13 | | 2014 | 4 | 2 | 6 | | 2015 | 3 | 0 | 3 | | 2016 | 3 | 2 | 5 | | 2017 | 4 | 5 | 9 |
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Below are the most recent publications written about "Calcium Signaling" by people in Profiles.
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Ferreira Gregorio J, Pequera G, Manno C, Ríos E, Brum G. The voltage sensor of excitation-contraction coupling in mammals: Inactivation and interaction with Ca2. J Gen Physiol. 2017 Nov 06; 149(11):1041-1058.
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Pereira L, Bare DJ, Galice S, Shannon TR, Bers DM. ß-Adrenergic induced SR Ca2+ leak is mediated by an Epac-NOS pathway. J Mol Cell Cardiol. 2017 07; 108:8-16.
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Karam C, Yi J, Xiao Y, Dhakal K, Zhang L, Li X, Manno C, Xu J, Li K, Cheng H, Ma J, Zhou J. Absence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation. Skelet Muscle. 2017 04 10; 7(1):6.
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Aguilar-Sanchez Y, Fainstein D, Mejia-Alvarez R, Escobar AL. Local Field Fluorescence Microscopy: Imaging Cellular Signals in Intact Hearts. J Vis Exp. 2017 03 08; (121).
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Kanaporis G, Blatter LA. Membrane potential determines calcium alternans through modulation of SR Ca2+ load and L-type Ca2+ current. J Mol Cell Cardiol. 2017 04; 105:49-58.
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Maxwell JT, Blatter LA. A novel mechanism of tandem activation of ryanodine receptors by cytosolic and SR luminal Ca2+ during excitation-contraction coupling in atrial myocytes. J Physiol. 2017 06 15; 595(12):3835-3845.
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Bovo E, Huke S, Blatter LA, Zima AV. The effect of PKA-mediated phosphorylation of ryanodine receptor on SR Ca2+ leak in ventricular myocytes. J Mol Cell Cardiol. 2017 03; 104:9-16.
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Uehara A, Murayama T, Yasukochi M, Fill M, Horie M, Okamoto T, Matsuura Y, Uehara K, Fujimoto T, Sakurai T, Kurebayashi N. Extensive Ca2+ leak through K4750Q cardiac ryanodine receptors caused by cytosolic and luminal Ca2+ hypersensitivity. J Gen Physiol. 2017 Feb; 149(2):199-218.
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Blatter LA. Tissue Specificity: SOCE: Implications for Ca2+ Handling in Endothelial Cells. Adv Exp Med Biol. 2017; 993:343-361.
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Søndergaard MT, Liu Y, Larsen KT, Nani A, Tian X, Holt C, Wang R, Wimmer R, Van Petegem F, Fill M, Chen SR, Overgaard MT. The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. J Biol Chem. 2017 01 27; 292(4):1385-1395.
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