 Calcium Signaling
"Calcium Signaling" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transduction mechanisms whereby calcium mobilization (from outside the cell or from intracellular storage pools) to the cytoplasm is triggered by external stimuli. Calcium signals are often seen to propagate as waves, oscillations, spikes, sparks, or puffs. The calcium acts as an intracellular messenger by activating calcium-responsive proteins.
| Descriptor ID |
D020013
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| MeSH Number(s) |
G02.111.087.800.800.100 G02.149.115.800.800.100 G03.495.166.500.100 G04.299.880.800.100
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| Concept/Terms |
Calcium Signaling- Calcium Signaling
- Calcium Signalings
- Signaling, Calcium
- Signalings, Calcium
Calcium Waves- Calcium Waves
- Calcium Wave
- Wave, Calcium
- Waves, Calcium
- Calcium Oscillations
- Calcium Oscillation
- Oscillation, Calcium
- Oscillations, Calcium
Calcium Spikes- Calcium Spikes
- Calcium Spike
- Spike, Calcium
- Spikes, Calcium
Calcium Puffs- Calcium Puffs
- Calcium Puff
- Puff, Calcium
- Puffs, Calcium
Calcium Sparks- Calcium Sparks
- Calcium Spark
- Spark, Calcium
- Sparks, Calcium
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Below are MeSH descriptors whose meaning is more general than "Calcium Signaling".
Below are MeSH descriptors whose meaning is more specific than "Calcium Signaling".
This graph shows the total number of publications written about "Calcium Signaling" by people in this website by year, and whether "Calcium Signaling" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 0 | 2 | | 2002 | 3 | 1 | 4 | | 2003 | 2 | 4 | 6 | | 2004 | 4 | 3 | 7 | | 2005 | 6 | 1 | 7 | | 2006 | 9 | 2 | 11 | | 2007 | 8 | 3 | 11 | | 2008 | 7 | 2 | 9 | | 2009 | 8 | 0 | 8 | | 2010 | 5 | 1 | 6 | | 2011 | 2 | 2 | 4 | | 2012 | 4 | 1 | 5 | | 2013 | 9 | 4 | 13 | | 2014 | 4 | 2 | 6 | | 2015 | 3 | 0 | 3 | | 2016 | 3 | 2 | 5 | | 2017 | 6 | 5 | 11 | | 2018 | 1 | 2 | 3 | | 2019 | 1 | 1 | 2 | | 2020 | 4 | 0 | 4 | | 2021 | 3 | 1 | 4 | | 2022 | 2 | 1 | 3 |
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Below are the most recent publications written about "Calcium Signaling" by people in Profiles.
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Martinez-Hernandez E, Kanaporis G, Blatter LA. Mechanism of carvedilol induced action potential and calcium alternans. Channels (Austin). 2022 Dec; 16(1):97-112.
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Manno C, Tammineni E, Figueroa L, Marty I, Ríos E. Quantification of the calcium signaling deficit in muscles devoid of triadin. PLoS One. 2022; 17(2):e0264146.
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Hamilton S, Terentyeva R, Bogdanov V, Kim TY, Perger F, Yan J, Ai X, Carnes CA, Belevych AE, George CH, Davis JP, Gyorke S, Choi BR, Terentyev D. Ero1a-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia. Circ Res. 2022 03 04; 130(5):711-724.
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Yin L, Zahradnikova A, Rizzetto R, Boncompagni S, Rabesahala de Meritens C, Zhang Y, Joanne P, Marqués-Sulé E, Aguilar-Sánchez Y, Fernández-Tenorio M, Villejoubert O, Li L, Wang YY, Mateo P, Nicolas V, Gerbaud P, Lai FA, Perrier R, Álvarez JL, Niggli E, Valdivia HH, Valdivia CR, Ramos-Franco J, Zorio E, Zissimopoulos S, Protasi F, Benitah JP, Gómez AM. Impaired Binding to Junctophilin-2 and Nanostructural Alteration in CPVT Mutation. Circ Res. 2021 07 23; 129(3):e35-e52.
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Bare DJ, Yue L, Ai X. A special issue on calcium dynamics of the heart: remodeling of ion channels and regulatory pathways. Pflugers Arch. 2021 03; 473(3):313-316.
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Fill M, Gillespie D. Simulating cardiac Ca2+ release units: effects of RyR cluster size and Ca2+ buffers on diastolic Ca2+ leak. Pflugers Arch. 2021 03; 473(3):435-446.
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McKee C, Bare DJ, Ai X. Stress-driven cardiac calcium mishandling via a kinase-to-kinase crosstalk. Pflugers Arch. 2021 03; 473(3):363-375.
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Yan J, Bare DJ, DeSantiago J, Zhao W, Mei Y, Chen Z, Ginsburg K, Solaro RJ, Wolska BM, Bers DM, Chen SRW, Ai X. JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship. Circ Res. 2021 02 19; 128(4):455-470.
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Oropeza-Almazán Y, Blatter LA. Mitochondrial calcium uniporter complex activation protects against calcium alternans in atrial myocytes. Am J Physiol Heart Circ Physiol. 2020 10 01; 319(4):H873-H881.
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Gussak G, Marszalec W, Yoo S, Modi R, O'Callaghan C, Aistrup GL, Cordeiro JM, Goodrow R, Kanaporis G, Blatter LA, Shiferaw Y, Arora R, Zhou J, Burrell AR, Wasserstrom JA. Triggered Ca2+ Waves Induce Depolarization of Maximum Diastolic Potential and Action Potential Prolongation in Dog Atrial Myocytes. Circ Arrhythm Electrophysiol. 2020 06; 13(6):e008179.
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