 Binding, Competitive
"Binding, Competitive" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The interaction of two or more substrates or ligands with the same binding site. The displacement of one by the other is used in quantitative and selective affinity measurements.
| Descriptor ID |
D001667
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| MeSH Number(s) |
E05.196.080 G02.111.087.090 G02.111.570.120.309 G02.149.115.090
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Binding, Competitive".
Below are MeSH descriptors whose meaning is more specific than "Binding, Competitive".
This graph shows the total number of publications written about "Binding, Competitive" by people in this website by year, and whether "Binding, Competitive" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1982 | 0 | 1 | 1 | | 1983 | 0 | 1 | 1 | | 1985 | 0 | 1 | 1 | | 1990 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1992 | 0 | 1 | 1 | | 1993 | 0 | 1 | 1 | | 1994 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 1 | 1 | | 1999 | 0 | 1 | 1 | | 2000 | 0 | 1 | 1 | | 2001 | 0 | 1 | 1 | | 2002 | 0 | 2 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 2 | 2 | | 2009 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Binding, Competitive" by people in Profiles.
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de Wolf C, van der Zee R, den Braber I, Glant T, Maillère B, Favry E, van Lummel M, Koning F, Hoek A, Ludwig I, van Eden W, Broere F. An Arthritis-Suppressive and Treg Cell-Inducing CD4+ T Cell Epitope Is Functional in the Context of HLA-Restricted T Cell Responses. Arthritis Rheumatol. 2016 Mar; 68(3):639-47.
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Lockett AD, Petrusca DN, Justice MJ, Poirier C, Serban KA, Rush NI, Kamocka M, Predescu D, Predescu S, Petrache I. Scavenger receptor class B, type I-mediated uptake of A1AT by pulmonary endothelial cells. Am J Physiol Lung Cell Mol Physiol. 2015 Aug 15; 309(4):L425-34.
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Boda D, Valiskó M, Henderson D, Eisenberg B, Gillespie D, Nonner W. Ionic selectivity in L-type calcium channels by electrostatics and hard-core repulsion. J Gen Physiol. 2009 May; 133(5):497-509.
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Wittwer AJ, Hills RL, Keith RH, Munie GE, Arner EC, Anglin CP, Malfait AM, Tortorella MD. Substrate-dependent inhibition kinetics of an active site-directed inhibitor of ADAMTS-4 (Aggrecanase 1). Biochemistry. 2007 May 29; 46(21):6393-401.
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DeCoursey TE, Cherny VV. Pharmacology of voltage-gated proton channels. Curr Pharm Des. 2007; 13(23):2400-20.
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Riccardi P, Li R, Ansari MS, Zald D, Park S, Dawant B, Anderson S, Doop M, Woodward N, Schoenberg E, Schmidt D, Baldwin R, Kessler R. Amphetamine-induced displacement of [18F] fallypride in striatum and extrastriatal regions in humans. Neuropsychopharmacology. 2006 May; 31(5):1016-26.
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Ji X, Olinger GG, Aris S, Chen Y, Gewurz H, Spear GT. Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus neutralization. J Gen Virol. 2005 Sep; 86(Pt 9):2535-2542.
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Cheung TC, Humphreys IR, Potter KG, Norris PS, Shumway HM, Tran BR, Patterson G, Jean-Jacques R, Yoon M, Spear PG, Murphy KM, Lurain NS, Benedict CA, Ware CF. Evolutionarily divergent herpesviruses modulate T cell activation by targeting the herpesvirus entry mediator cosignaling pathway. Proc Natl Acad Sci U S A. 2005 Sep 13; 102(37):13218-23.
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Rosenkilde MM, McLean KA, Holst PJ, Schwartz TW. The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins. J Biol Chem. 2004 Jul 30; 279(31):32524-33.
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Srinivasan C, Toon J, Amari L, Abukhdeir AM, Hamm H, Geraldes CF, Ho YK, Mota de Freitas D. Competition between lithium and magnesium ions for the G-protein transducin in the guanosine 5'-diphosphate bound conformation. J Inorg Biochem. 2004 May; 98(5):691-701.
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