"Spermine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic polyamine formed from spermidine. It is found in a wide variety of organisms and tissues and is an essential growth factor in some bacteria. It is found as a polycation at all pH values. Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.
Descriptor ID |
D013096
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MeSH Number(s) |
D02.092.211.415.701.801.821 D02.092.782.802
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Spermine".
Below are MeSH descriptors whose meaning is more specific than "Spermine".
This graph shows the total number of publications written about "Spermine" by people in this website by year, and whether "Spermine" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2014 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spermine" by people in Profiles.
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Mitochondrial calcium uniporter complex activation protects against calcium alternans in atrial myocytes. Am J Physiol Heart Circ Physiol. 2020 10 01; 319(4):H873-H881.
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Cardiac responses to ß-adrenoceptor stimulation is partly dependent on mitochondrial calcium uniporter activity. Br J Pharmacol. 2014 Sep; 171(18):4207-21.
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Modulation of mitochondrial Ca2+ by nitric oxide in cultured bovine vascular endothelial cells. Am J Physiol Cell Physiol. 2005 Oct; 289(4):C836-45.
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Rectification of rabbit cardiac ryanodine receptor current by endogenous polyamines. Biophys J. 1996 Aug; 71(2):769-77.