"ADAM Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of membrane-anchored glycoproteins that contain a disintegrin and metalloprotease domain. They are responsible for the proteolytic cleavage of many transmembrane proteins and the release of their extracellular domain.
| Descriptor ID |
D051722
|
| MeSH Number(s) |
D08.811.277.656.675.374.102 D09.400.430.500 D12.776.395.033
|
| Concept/Terms |
ADAM Proteins- ADAM Proteins
- A Disintegrin and Metalloprotease Proteins
- ADAM (A Disintegrin and Metalloprotease) Proteins
|
Below are MeSH descriptors whose meaning is more general than "ADAM Proteins".
Below are MeSH descriptors whose meaning is more specific than "ADAM Proteins".
This graph shows the total number of publications written about "ADAM Proteins" by people in this website by year, and whether "ADAM Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 2 | 0 | 2 |
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Below are the most recent publications written about "ADAM Proteins" by people in Profiles.
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Therapeutic effects of an anti-ADAMTS-5 antibody on joint damage and mechanical allodynia in a murine model of osteoarthritis. Osteoarthritis Cartilage. 2016 Feb; 24(2):299-306.
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Translational development of an ADAMTS-5 antibody for osteoarthritis disease modification. Osteoarthritis Cartilage. 2015 Aug; 23(8):1254-66.
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Regulation of anabolic and catabolic gene expression in normal and osteoarthritic adult human articular chondrocytes by osteogenic protein-1. Clin Exp Rheumatol. 2004 Jan-Feb; 22(1):103-6.
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ADAM-10 protein is present in human articular cartilage primarily in the membrane-bound form and is upregulated in osteoarthritis and in response to IL-1alpha in bovine nasal cartilage. J Histochem Cytochem. 2001 Sep; 49(9):1165-76.
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ADAM-10 message is expressed in human articular cartilage. J Histochem Cytochem. 1998 Jun; 46(6):723-9.