"Lactoferrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An iron-binding protein that was originally characterized as a milk protein. It is widely distributed in secretory fluids and is found in the neutrophilic granules of LEUKOCYTES. The N-terminal part of lactoferrin possesses a serine protease which functions to inactivate the TYPE III SECRETION SYSTEM used by bacteria to export virulence proteins for host cell invasion.
| Descriptor ID |
D007781
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| MeSH Number(s) |
D08.811.277.656.300.760.471 D08.811.277.656.959.350.471 D12.776.157.427.750.249 D12.776.256.626.816.500.507 D12.776.377.457.507 D12.776.395.507 D12.776.556.579.750.249
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lactoferrin".
Below are MeSH descriptors whose meaning is more specific than "Lactoferrin".
This graph shows the total number of publications written about "Lactoferrin" by people in this website by year, and whether "Lactoferrin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 2 | 0 | 2 |
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Below are the most recent publications written about "Lactoferrin" by people in Profiles.
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Bovine lactoferricin-induced anti-inflammation is, in part, via up-regulation of interleukin-11 by secondary activation of STAT3 in human articular cartilage. J Biol Chem. 2013 Nov 01; 288(44):31655-69.
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Bovine lactoferricin is anti-inflammatory and anti-catabolic in human articular cartilage and synovium. J Cell Physiol. 2013 Feb; 228(2):447-56.