Urokinase-Type Plasminogen Activator
"Urokinase-Type Plasminogen Activator" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A proteolytic enzyme that converts PLASMINOGEN to FIBRINOLYSIN where the preferential cleavage is between ARGININE and VALINE. It was isolated originally from human URINE, but is found in most tissues of most VERTEBRATES.
Descriptor ID |
D014568
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MeSH Number(s) |
D08.811.277.656.300.760.910 D08.811.277.656.959.350.910 D12.776.124.125.662.884
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Concept/Terms |
Urokinase-Type Plasminogen Activator- Urokinase-Type Plasminogen Activator
- Urokinase Type Plasminogen Activator
- Plasminogen Activator, Urokinase-Type
- U-Plasminogen Activator
- U Plasminogen Activator
- U-PA
- Urinary Plasminogen Activator
- Urokinase
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Below are MeSH descriptors whose meaning is more general than "Urokinase-Type Plasminogen Activator".
Below are MeSH descriptors whose meaning is more specific than "Urokinase-Type Plasminogen Activator".
This graph shows the total number of publications written about "Urokinase-Type Plasminogen Activator" by people in this website by year, and whether "Urokinase-Type Plasminogen Activator" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2020 | 1 | 0 | 1 |
2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Urokinase-Type Plasminogen Activator" by people in Profiles.
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Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis. J Clin Invest. 2022 12 15; 132(24).
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Soluble Urokinase Plasminogen Activator Receptor and Venous Thromboembolism in COVID-19. J Am Heart Assoc. 2022 09 20; 11(18):e025198.
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Soluble Urokinase Receptor and Mortality in Kidney Transplant Recipients. Transpl Int. 2021; 35:10071.
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Soluble Urokinase Receptor and Acute Kidney Injury. Reply. N Engl J Med. 2020 05 28; 382(22):2167-2168.
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Soluble Urokinase Receptor and Acute Kidney Injury. N Engl J Med. 2020 01 30; 382(5):416-426.
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Podocyte injury-driven intracapillary plasminogen activator inhibitor type 1 accelerates podocyte loss via uPAR-mediated ?1-integrin endocytosis. Am J Physiol Renal Physiol. 2015 Mar 15; 308(6):F614-26.
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Acute occlusion of popliteal and/or tibial arteries: the value of percutaneous treatment. Eur J Vasc Endovasc Surg. 2000 Aug; 20(2):138-45.
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A grading scale to predict outcomes after intra-arterial thrombolysis for stroke complicated by contrast extravasation. Neurosurgery. 2000 Jun; 46(6):1307-14; discussion 1314-5.
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Improved cerebral perfusion after stenting of a petrous carotid stenosis: technical case report. Neurosurgery. 1999 Sep; 45(3):638-42.
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Production of recombinant proteins in Chinese hamster ovary cells using a protein-free cell culture medium. Biotechnology (N Y). 1995 Apr; 13(4):389-92.