"Protein Phosphatase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A eukayrotic protein serine-threonine phosphatase subtype that dephosphorylates a wide variety of cellular proteins. The enzyme is comprised of a catalytic subunit and regulatory subunit. Several isoforms of the protein phosphatase catalytic subunit exist due to the presence of multiple genes and the alternative splicing of their mRNAs. A large number of proteins have been shown to act as regulatory subunits for this enzyme. Many of the regulatory subunits have additional cellular functions.
Descriptor ID |
D054645
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MeSH Number(s) |
D08.811.277.352.650.625.687
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Concept/Terms |
Protein Phosphatase 1- Protein Phosphatase 1
- Protein Phosphatase-1
- Type 1 Serine Threonine Protein Phosphatase
- PP1c Enzyme
|
Below are MeSH descriptors whose meaning is more general than "Protein Phosphatase 1".
Below are MeSH descriptors whose meaning is more specific than "Protein Phosphatase 1".
This graph shows the total number of publications written about "Protein Phosphatase 1" by people in this website by year, and whether "Protein Phosphatase 1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Phosphatase 1" by people in Profiles.
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Protein Phosphatase 1 Beta is Modulated by Chronic Hypoxia and Involved in the Angiogenic Endothelial Cell Migration. Cell Physiol Biochem. 2015; 36(1):384-94.
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Repeated cocaine administration decreases calcineurin (PP2B) but enhances DARPP-32 modulation of sodium currents in rat nucleus accumbens neurons. Neuropsychopharmacology. 2005 May; 30(5):916-26.
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Inhibitors of protein phosphatase 1 and 2A differentially regulate the expression of inducible nitric-oxide synthase in rat astrocytes and macrophages. J Biol Chem. 1998 May 15; 273(20):12219-26.