Tartrate-Resistant Acid Phosphatase
"Tartrate-Resistant Acid Phosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of several acid phosphatases in humans, other mammals, plants, and a few prokaryotes. The protein fold of tartrate-resistant acid phosphatase (TRAP) resembles that of the catalytic domain of plant purple acid phosphatase and other serine/threonine-protein phosphatases that also contain a metallophosphoesterase domain. One gene produces the various forms which include purple acid phosphatases from spleen and other tissues. Tartrate-resistant acid phosphatase is a biomarker for pathological states in which it is over-expressed. Such conditions include GAUCHER DISEASE; HODGKIN DISEASE; BONE RESORPTION; and NEOPLASM METASTASIS.
Descriptor ID |
D000071681
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MeSH Number(s) |
D08.811.277.352.650.025.500 D08.811.277.352.650.625.862
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Concept/Terms |
Tartrate-Resistant Acid Phosphatase- Tartrate-Resistant Acid Phosphatase
- Acid Phosphatase, Tartrate-Resistant
- Phosphatase, Tartrate-Resistant Acid
- Tartrate Resistant Acid Phosphatase
- TRAcP
TRAP Type 5 AcPase- TRAP Type 5 AcPase
- Acid Phosphatase V
- Phosphatase V, Acid
- V, Acid Phosphatase
- AcPase V
- V, AcPase
- Type 5 Acid Phosphatase
- Tartrate-Resistant Acid Phosphatase Type 5
- Tartrate Resistant Acid Phosphatase Type 5
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