"Cardiomegaly" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Descriptor ID |
D006332
|
| MeSH Number(s) |
C14.280.195 C23.300.775.250
|
| Concept/Terms |
Cardiomegaly- Cardiomegaly
- Heart Enlargement
- Enlargement, Heart
- Enlarged Heart
- Heart, Enlarged
|
Below are MeSH descriptors whose meaning is more general than "Cardiomegaly".
Below are MeSH descriptors whose meaning is more specific than "Cardiomegaly".
This graph shows the total number of publications written about "Cardiomegaly" by people in this website by year, and whether "Cardiomegaly" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cardiomegaly" by people in Profiles.
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The cardiac ryanodine receptor luminal Ca2+ sensor governs Ca2+ waves, ventricular tachyarrhythmias and cardiac hypertrophy in calsequestrin-null mice. Biochem J. 2014 Jul 01; 461(1):99-106.
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The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy. J Mol Cell Cardiol. 2014 Jan; 66:27-40.
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Functional integrity of the T-tubular system in cardiomyocytes depends on p21-activated kinase 1. J Mol Cell Cardiol. 2013 Jul; 60:121-8.
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Ca flux, contractility, and excitation-contraction coupling in hypertrophic rat ventricular myocytes. Am J Physiol. 1998 04; 274(4):H1348-60.