"Connexin 43" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 43-kDa peptide which is a member of the connexin family of gap junction proteins. Connexin 43 is a product of a gene in the alpha class of connexin genes (the alpha-1 gene). It was first isolated from mammalian heart, but is widespread in the body including the brain.
| Descriptor ID |
D018031
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| MeSH Number(s) |
D12.776.543.585.250.200
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Connexin 43".
Below are MeSH descriptors whose meaning is more specific than "Connexin 43".
This graph shows the total number of publications written about "Connexin 43" by people in this website by year, and whether "Connexin 43" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
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Below are the most recent publications written about "Connexin 43" by people in Profiles.
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Regulation of cardiac gap junctions by protein phosphatases. J Mol Cell Cardiol. 2017 06; 107:52-57.
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Connexin40 abnormalities and atrial fibrillation in the human heart. J Mol Cell Cardiol. 2014 Nov; 76:159-68.
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Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signaling. Am J Physiol Heart Circ Physiol. 2013 Feb 15; 304(4):H600-9.
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Enhanced activation of p21-activated kinase 1 in heart failure contributes to dephosphorylation of connexin 43. Cardiovasc Res. 2011 Oct 01; 92(1):106-14.
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Connexin43 knockdown or overexpression modulates cell coupling in control and failing rabbit left ventricular myocytes. Cardiovasc Res. 2010 Mar 01; 85(4):751-62.