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Patricia A Boyle

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentBehavioral Sciences and Health Psychology
Address600 S. Paulina St.
Chicago IL 60612
Phone312-942-8749
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    Patricia Boyle, PhD, is a neuropsychologist with the Rush Alzheimer’s Disease Center and associate professor in the Department of Behavioral Sciences. Boyle’s primary interest is the prevention of age-related cognitive and functional decline and dementia. Her research examines risk factors for and the neuropathologic basis of age related changes in cognition, decision making and physical function. The goal of this research is to identify factors that promote health and well being in late life. Boyle has published extensively in the areas of cognitive aging, Alzheimer’s disease and functional status, and her research is funded by the National Institute on Aging.

    My Scopus ID is 55651785200.
    My NIH COMMONS name is PBOYLE.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ng TKS, Beck T, Boyle P, Dhana K, Desai P, Evans DA, Rajan KB. APOE4, Blood Neurodegenerative Biomarkers, and Cognitive Decline in Community-Dwelling Older Adults. JAMA Netw Open. 2025 May 01; 8(5):e258903. PMID: 40332937; PMCID: PMC12059971.
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    2. Yu L, Wang T, Wilson RS, Leurgans S, Schneider JA, Bennett DA, Boyle PA. Common age-related neuropathologies and yearly variability in cognition. Ann Clin Transl Neurol. 2019 11; 6(11):2140-2149. PMID: 31568713.
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    3. Wilson RS, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Bennett DA, Boyle PA. Postmortem neurodegenerative markers and trajectories of decline in cognitive systems. Neurology. 2019 02 19; 92(8):e831-e840. PMID: 30674595.
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    4. Kapasi A, Leurgans SE, James BD, Boyle PA, Arvanitakis Z, Nag S, Bennett DA, Buchman AS, Schneider JA. Watershed microinfarct pathology and cognition in older persons. Neurobiol Aging. 2018 10; 70:10-17. PMID: 29935416.
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    5. Wilson RS, Capuano AW, Yu L, Yang J, Kim N, Leurgans SE, Lamar M, Schneider JA, Bennett DA, Boyle PA. Neurodegenerative disease and cognitive retest learning. Neurobiol Aging. 2018 06; 66:122-130. PMID: 29558667.
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    6. Stewart CC, Yu L, Wilson RS, Bennett DA, Boyle PA. Correlates of healthcare and financial decision making among older adults without dementia. Health Psychol. 2018 07; 37(7):618-626. PMID: 29565601.
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    7. Boyle PA, Yu L, Wilson RS, Leurgans SE, Schneider JA, Bennett DA. Person-specific contribution of neuropathologies to cognitive loss in old age. Ann Neurol. 2018 01; 83(1):74-83. PMID: 29244218.
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    8. Yu L, Dawe RJ, Boyle PA, Gaiteri C, Yang J, Buchman AS, Schneider JA, Arfanakis K, De Jager PL, Bennett DA. Association Between Brain Gene Expression, DNA Methylation, and Alteration of Ex Vivo Magnetic Resonance Imaging Transverse Relaxation in Late-Life Cognitive Decline. JAMA Neurol. 2017 12 01; 74(12):1473-1480. PMID: 29084334.
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    9. Jansen WJ, Wilson RS, Visser PJ, Nag S, Schneider JA, James BD, Leurgans SE, Capuano AW, Bennett DA, Boyle PA. Age and the association of dementia-related pathology with trajectories of cognitive decline. Neurobiol Aging. 2018 01; 61:138-145. PMID: 29078129.
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    10. Wilson RS, Capuano AW, James BD, Amofa P, Arvanitakis Z, Shah R, Bennett DA, Boyle PA. Purpose in Life and Hospitalization for Ambulatory Care-Sensitive Conditions in Old Age. Am J Geriatr Psychiatry. 2018 03; 26(3):364-374. PMID: 28780129.
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    11. Yu L, Wilson RS, Han SD, Leurgans S, Bennett DA, Boyle PA. Decline in Literacy and Incident AD Dementia Among Community-Dwelling Older Persons. J Aging Health. 2018 10; 30(9):1389-1405. PMID: 28645223.
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    12. Boyle PA, Yang J, Yu L, Leurgans SE, Capuano AW, Schneider JA, Wilson RS, Bennett DA. Varied effects of age-related neuropathologies on the trajectory of late life cognitive decline. Brain. 2017 03 01; 140(3):804-812. PMID: 28082297.
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    13. Yu L, Wilson RS, Schneider JA, Bennett DA, Boyle PA. Financial and Health Literacy Predict Incident Alzheimer's Disease Dementia and Pathology. J Alzheimers Dis. 2017; 56(4):1485-1493. PMID: 28157101.
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    14. James BD, Wilson RS, Boyle PA, Trojanowski JQ, Bennett DA, Schneider JA. TDP-43 stage, mixed pathologies, and clinical Alzheimer's-type dementia. Brain. 2016 11 01; 139(11):2983-2993. PMID: 27694152.
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    15. Boyle PA, Yu L, Fleischman DA, Leurgans S, Yang J, Wilson RS, Schneider JA, Arvanitakis Z, Arfanakis K, Bennett DA. White matter hyperintensities, incident mild cognitive impairment, and cognitive decline in old age. Ann Clin Transl Neurol. 2016 10; 3(10):791-800. PMID: 27752514.
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    16. Wilson RS, Sytsma J, Barnes LL, Boyle PA. Anosognosia in Dementia. Curr Neurol Neurosci Rep. 2016 09; 16(9):77. PMID: 27438597.
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    17. Wilson RS, Yu L, James BD, Bennett DA, Boyle PA. Association of financial and health literacy with cognitive health in old age. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2017 Mar; 24(2):186-197. PMID: 27263546.
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    18. Okbay A, Beauchamp JP, Fontana MA, Lee JJ, Pers TH, Rietveld CA, Turley P, Chen GB, Emilsson V, Meddens SF, Oskarsson S, Pickrell JK, Thom K, Timshel P, de Vlaming R, Abdellaoui A, Ahluwalia TS, Bacelis J, Baumbach C, Bjornsdottir G, Brandsma JH, Pina Concas M, Derringer J, Furlotte NA, Galesloot TE, Girotto G, Gupta R, Hall LM, Harris SE, Hofer E, Horikoshi M, Huffman JE, Kaasik K, Kalafati IP, Karlsson R, Kong A, Lahti J, van der Lee SJ, deLeeuw C, Lind PA, Lindgren KO, Liu T, Mangino M, Marten J, Mihailov E, Miller MB, van der Most PJ, Oldmeadow C, Payton A, Pervjakova N, Peyrot WJ, Qian Y, Raitakari O, Rueedi R, Salvi E, Schmidt B, Schraut KE, Shi J, Smith AV, Poot RA, St Pourcain B, Teumer A, Thorleifsson G, Verweij N, Vuckovic D, Wellmann J, Westra HJ, Yang J, Zhao W, Zhu Z, Alizadeh BZ, Amin N, Bakshi A, Baumeister SE, Biino G, B?nnelykke K, Boyle PA, Campbell H, Cappuccio FP, Davies G, De Neve JE, Deloukas P, Demuth I, Ding J, Eibich P, Eisele L, Eklund N, Evans DM, Faul JD, Feitosa MF, Forstner AJ, Gandin I, Gunnarsson B, Halld?rsson BV, Harris TB, Heath AC, Hocking LJ, Holliday EG, Homuth G, Horan MA, Hottenga JJ, de Jager PL, Joshi PK, Jugessur A, Kaakinen MA, K?h?nen M, Kanoni S, Keltigangas-J?rvinen L, Kiemeney LA, Kolcic I, Koskinen S, Kraja AT, Kroh M, Kutalik Z, Latvala A, Launer LJ, Lebreton MP, Levinson DF, Lichtenstein P, Lichtner P, Liewald DC, Loukola A, Madden PA, M?gi R, M?ki-Opas T, Marioni RE, Marques-Vidal P, Meddens GA, McMahon G, Meisinger C, Meitinger T, Milaneschi Y, Milani L, Montgomery GW, Myhre R, Nelson CP, Nyholt DR, Ollier WE, Palotie A, Paternoster L, Pedersen NL, Petrovic KE, Porteous DJ, R?ikk?nen K, Ring SM, Robino A, Rostapshova O, Rudan I, Rustichini A, Salomaa V, Sanders AR, Sarin AP, Schmidt H, Scott RJ, Smith BH, Smith JA, Staessen JA, Steinhagen-Thiessen E, Strauch K, Terracciano A, Tobin MD, Ulivi S, Vaccargiu S, Quaye L, van Rooij FJ, Venturini C, Vinkhuyzen AA, V?lker U, V?lzke H, Vonk JM, Vozzi D, Waage J, Ware EB, Willemsen G, Attia JR, Bennett DA, Berger K, Bertram L, Bisgaard H, Boomsma DI, Borecki IB, B?ltmann U, Chabris CF, Cucca F, Cusi D, Deary IJ, Dedoussis GV, van Duijn CM, Eriksson JG, Franke B, Franke L, Gasparini P, Gejman PV, Gieger C, Grabe HJ, Gratten J, Groenen PJ, Gudnason V, van der Harst P, Hayward C, Hinds DA, Hoffmann W, Hypp?nen E, Iacono WG, Jacobsson B, J?rvelin MR, J?ckel KH, Kaprio J, Kardia SL, Lehtim?ki T, Lehrer SF, Magnusson PK, Martin NG, McGue M, Metspalu A, Pendleton N, Penninx BW, Perola M, Pirastu N, Pirastu M, Polasek O, Posthuma D, Power C, Province MA, Samani NJ, Schlessinger D, Schmidt R, S?rensen TI, Spector TD, Stefansson K, Thorsteinsdottir U, Thurik AR, Timpson NJ, Tiemeier H, Tung JY, Uitterlinden AG, Vitart V, Vollenweider P, Weir DR, Wilson JF, Wright AF, Conley DC, Krueger RF, Davey Smith G, Hofman A, Laibson DI, Medland SE, Meyer MN, Yang J, Johannesson M, Visscher PM, Esko T, Koellinger PD, Cesarini D, Benjamin DJ. Genome-wide association study identifies 74 loci associated with educational attainment. Nature. 2016 05 26; 533(7604):539-42. PMID: 27225129.
      Citations:    
    19. Wilson RS, Capuano AW, Bennett DA, Schneider JA, Boyle PA. Temporal course of neurodegenerative effects on cognition in old age. Neuropsychology. 2016 07; 30(5):591-9. PMID: 27111293.
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    20. Wilson RS, Boyle PA, Capuano AW, Shah RC, Hoganson GM, Nag S, Bennett DA. Late-life depression is not associated with dementia-related pathology. Neuropsychology. 2016 Feb; 30(2):135-42. PMID: 26237627.
      Citations:    
    21. Boyle PA, Yu L, Nag S, Leurgans S, Wilson RS, Bennett DA, Schneider JA. Cerebral amyloid angiopathy and cognitive outcomes in community-based older persons. Neurology. 2015 Dec 01; 85(22):1930-6. PMID: 26537052.
      Citations:    
    22. Buchman AS, Wilson RS, Yu L, Boyle PA, Bennett DA, Barnes LL. Motor Function Is Associated With Incident Disability in Older African Americans. J Gerontol A Biol Sci Med Sci. 2016 May; 71(5):696-702. PMID: 26525087.
      Citations:    
    23. Wilson RS, Boyle PA, Yu L, Barnes LL, Sytsma J, Buchman AS, Bennett DA, Schneider JA. Temporal course and pathologic basis of unawareness of memory loss in dementia. Neurology. 2015 Sep 15; 85(11):984-91. PMID: 26311746.
      Citations:    
    24. Yu L, Boyle PA, Nag S, Leurgans S, Buchman AS, Wilson RS, Arvanitakis Z, Farfel JM, De Jager PL, Bennett DA, Schneider JA. APOE and cerebral amyloid angiopathy in community-dwelling older persons. Neurobiol Aging. 2015 Nov; 36(11):2946-2953. PMID: 26341746.
      Citations:    
    25. Yu L, Boyle PA, Leurgans S, Schneider JA, Kryscio RJ, Wilson RS, Bennett DA. Effect of common neuropathologies on progression of late life cognitive impairment. Neurobiol Aging. 2015 Jul; 36(7):2225-2231. PMID: 25976345.
      Citations:    
    26. Yu L, Boyle PA, Wilson RS, Levine SR, Schneider JA, Bennett DA. Purpose in life and cerebral infarcts in community-dwelling older people. Stroke. 2015 Apr; 46(4):1071-6. PMID: 25791714.
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    27. Wilson RS, Boyle PA, Yu L, Segawa E, Sytsma J, Bennett DA. Conscientiousness, dementia related pathology, and trajectories of cognitive aging. Psychol Aging. 2015 Mar; 30(1):74-82. PMID: 25664558.
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    28. Yu L, Boyle PA, Segawa E, Leurgans S, Schneider JA, Wilson RS, Bennett DA. Residual decline in cognition after adjustment for common neuropathologic conditions. Neuropsychology. 2015 May; 29(3):335-43. PMID: 25495832.
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    29. Wilson RS, Boyle PA, James BD, Leurgans SE, Buchman AS, Bennett DA. Negative social interactions and risk of mild cognitive impairment in old age. Neuropsychology. 2015 Jul; 29(4):561-70. PMID: 25495828.
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    30. Buchman AS, Boyle PA, Yu L, Shah RC, Wilson RS, Bennett DA. Total daily physical activity and the risk of AD and cognitive decline in older adults. Neurology. 2012 Apr 24; 78(17):1323-9. PMID: 22517108.
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    31. Wilson RS, Krueger KR, Boyle PA, Bennett DA. Loss of basic lexical knowledge in old age. J Neurol Neurosurg Psychiatry. 2011 Apr; 82(4):369-72. PMID: 20802026.
      Citations:    
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