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Konstantinos Arfanakis

TitleProfessor
InstitutionRush University, Rush Medical College
DepartmentDiagnostic Radiology and Nuclear Medicine
Address
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    Collapse Biography 
    Collapse awards and honors
    1999Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2000Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2001Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2001Vilas Fellowship
    2002Student Stipend, International Society for Magnetic Resonance in Medicine (ISMRM)
    2002Magna Cum Laude, Radiological Society of North America (RSNA)
    2002Excellence in Design of Education Exhibit, Radiological Society of North America (RSNA)
    2002Figures from journal article AJNR Am. J. Neuroradiol 2002;23:794-802, Cover of that issue of the journal
    2003Journal article Magn. Reson. Med. 2002;47:354-363 was ranked in the Top 10 most assessed papers , Magnetic Resonance in Medicine for the period 2002-2003
    2004Dean's commendation for receiving outstanding teaching evaluations for my BME 535 course
    2005Dean's commendation for receiving outstanding teaching evaluations for my BME 430 course
    2006Dean's commendation for receiving outstanding teaching evaluations for my BME 438 course
    2007Sigma Xi / IIT Award for Excellence in University Research, Junior faculty category
    2008Top 3 for the Bodossaki Foundation Academic Prize , "Theories, Methods, and Techniques, of Biomedical Applications of Informtics and Telecommunications"
    2009Journal article Neuroimage 2009;46:967-980 ranked #11, List of "hottest articles" in Neuromage for April-June (out of 168 papers)
    2010Journal article Am. J. Neuroradiol. 2002:23:794-802 ranked #28, Most Frequently Cited Article in the history of the journal
    2012ISMRM Magna Cum Laude Merit Award, 20th Annual ISMRM international conference
    2012Journal article Nat Genet 2012;44:545-552, received the "Best paper" award, 2012 de Leon Prize in Neuroimaging
    2015Merit Abstract Award, Organization for Human Brain Mapping
    2015ISMRM Summa Cum Laude Merit Award, 23rd Annuial ISMRM international conference
    2017Scientific Sessions, Best Nursing Abstract, American Heart Association
    2017ISMRM Magna Cum Laude Merit Award, 25th Annual ISMRM international conference

    Collapse Overview 
    Collapse overview
    Konstantinos Arfanakis, PhD, is Professor of Biomedical Engineering at the Illinois Institute of Technology, and Leader of the Imaging and Bioengineering Studies at the Rush Alzheimer’s Disease Center. Dr. Arfanakis has expertise in MRI pulse sequence development, image reconstruction, and image processing. His research focuses on multi-parametric MRI in aging and dementia, ex-vivo brain MRI, and brain atlas development.

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zanon Zotin MC, Makkinejad N, Schneider JA, Arfanakis K, Charidimou A, Greenberg SM, van Veluw SJ. Sensitivity and Specificity of the Boston Criteria Version 2.0 for the Diagnosis of Cerebral Amyloid Angiopathy in a Community-Based Sample. Neurology. 2024 Jan 09; 102(1):e207940. PMID: 38165367.
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    2. Lamar M, Arfanakis K, Evia A, Makkinejad N, Capuano AW, Kim N, Leurgans SE, Fleischman DA, Duke Han S, Poole V, Barnes LL. Changes in an in-vivo classifier of ARTerioloSclerosis (ARTS) with simultaneous change in cognition for older African Americans. Neurobiol Aging. 2024 Feb; 134:21-27. PMID: 37979249.
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    3. Poole VN, Oveisgharan S, Yu L, Dawe RJ, Leurgans SE, Zhang S, Arfanakis K, Buchman AS, Bennett DA. Volumetric brain correlates of gait associated with cognitive decline in community-dwelling older adults. Front Aging Neurosci. 2023; 15:1194986. PMID: 37860122.
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    4. Wu Y, Ridwan AR, Niaz MR, Bennett DA, Arfanakis K. High resolution 0.5mm isotropic T1-weighted and diffusion tensor templates of the brain of non-demented older adults in a common space for the MIITRA atlas. Neuroimage. 2023 11 15; 282:120387. PMID: 37783362.
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    5. Wang Z, Wang J, Guo J, Dove A, Arfanakis K, Qi X, Bennett DA, Xu W. Association of Motor Function With Cognitive Trajectories and Structural Brain Differences: A Community-Based Cohort Study. Neurology. 2023 10 24; 101(17):e1718-e1728. PMID: 37657942.
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    6. Wuestefeld A, Pichet Binette A, Berron D, Spotorno N, van Westen D, Stomrud E, Mattsson-Carlgren N, Strandberg O, Smith R, Palmqvist S, Glenn T, Moes S, Honer M, Arfanakis K, Barnes LL, Bennett DA, Schneider JA, Wisse LEM, Hansson O. Age-related and amyloid-beta-independent tau deposition and its downstream effects. Brain. 2023 08 01; 146(8):3192-3205. PMID: 37082959.
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    7. Lamar M, Arfanakis K, Yu L, Kapasi A, Duke Han S, Fleischman DA, Bennett DA, Boyle P. The Relationship of MRI-Derived Alzheimer's and Cerebrovascular-Related Signatures With Level of and Change in Health and Financial Literacy. Am J Geriatr Psychiatry. 2023 12; 31(12):1129-1139. PMID: 37541932.
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    8. Barnes LL, Dhana K, Liu X, Carey VJ, Ventrelle J, Johnson K, Hollings CS, Bishop L, Laranjo N, Stubbs BJ, Reilly X, Agarwal P, Zhang S, Grodstein F, Tangney CC, Holland TM, Aggarwal NT, Arfanakis K, Morris MC, Sacks FM. Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons. N Engl J Med. 2023 Aug 17; 389(7):602-611. PMID: 37466280.
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    9. Liu X, Barisano G, Shao X, Jann K, Ringman JM, Lu H, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Maillard P, Satizabal CL, Fadaee E, Habes M, Stables L, Singh H, Fischl B, Kouwe AV, Schwab K, Helmer KG, Greenberg SM, Wang DJJ. Cross-Vendor Test-Retest Validation of Diffusion Tensor Image Analysis along the Perivascular Space (DTI-ALPS) for Evaluating Glymphatic System Function. Aging Dis. 2023 May 26. PMID: 37307817.
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    10. Nikseresht G, Evia AM, Nag S, Leurgans SE, Capuano AW, Agam G, Barnes LL, Bennett DA, Schneider JA, Arfanakis K. Neuropathologic correlates of cerebral microbleeds in community-based older adults. Neurobiol Aging. 2023 09; 129:89-98. PMID: 37279617.
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    11. Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Lamar M, Han SD, Poole VN, Kim N, Bennett DA, Barnes LL. Late-life depressive symptoms and white matter structural integrity within older Black adults. Front Aging Neurosci. 2023; 15:1138568. PMID: 37205056.
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    12. Lee AJ, Ma Y, Yu L, Dawe RJ, McCabe C, Arfanakis K, Mayeux R, Bennett DA, Klein HU, De Jager PL. Multi-region brain transcriptomes uncover two subtypes of aging individuals with differences in Alzheimer risk and the impact of APOEe4. bioRxiv. 2023 Jan 25. PMID: 36747803.
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    13. Fleischman DA, Arfanakis K, Zhang S, Leurgans SE, Barnes LL, Bennett DA, Marquez DX, Lamar M. Acculturation in Context and Brain Health in Older Latino Adults: A Diffusion Tensor Imaging Study. J Alzheimers Dis. 2023; 95(4):1585-1595. PMID: 37718813.
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    14. Glover CM, Arfanakis K, Aggarwal NT, Bennett DA, Marquez DX, Barnes LL. A Qualitative Examination of Knowledge, Experiences, and Considerations of PET Brain Scan Participation Among Older Black and Latino Adults. J Alzheimers Dis. 2023; 91(3):961-976. PMID: 36530086.
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    15. Bahrani AA, Abner EL, DeCarli CS, Barber JM, Sutton AC, Maillard P, Sandoval F, Arfanakis K, Yang YC, Evia AM, Schneider JA, Habes M, Franklin CG, Seshadri S, Satizabal CL, Caprihan A, Thompson JF, Rosenberg GA, Wang DJJ, Jann K, Zhao C, Lu H, Rosenberg PB, Albert MS, Ali DG, Singh H, Schwab K, Greenberg SM, Helmer KG, Powel DK, Gold BT, Goldstein LB, Wilcock DM, Jicha GA. Multi-Site Cross-Site Inter-Rater and Test-Retest Reliability and Construct Validity of the MarkVCID White Matter Hyperintensity Growth and Regression Protocol. J Alzheimers Dis. 2023; 96(2):683-693. PMID: 37840499.
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    16. Agrawal S, Farfel JM, Arfanakis K, Al-Harthi L, Shull T, Teppen TL, Evia AM, Patel MB, Ely EW, Leurgans SE, Bennett DA, Mehta R, Schneider JA. Brain autopsies of critically ill COVID-19 patients demonstrate heterogeneous profile of acute vascular injury, inflammation and age-linked chronic brain diseases. Acta Neuropathol Commun. 2022 Dec 17; 10(1):186. PMID: 36528671.
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    17. Maillard P, Hillmer LJ, Lu H, Arfanakis K, Gold BT, Bauer CE, Kramer JH, Staffaroni AM, Stables L, Wang DJJ, Seshadri S, Satizabal CL, Beiser A, Habes M, Fornage M, Mosley TH, Rosenberg GA, Singh B, Singh H, Schwab K, Helmer KG, Greenberg SM, DeCarli C, Caprihan A. MRI free water as a biomarker for cognitive performance: Validation in the MarkVCID consortium. Alzheimers Dement (Amst). 2022; 14(1):e12362. PMID: 36523847.
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    18. Nelson PT, Lee EB, Cykowski MD, Alafuzoff I, Arfanakis K, Attems J, Brayne C, Corrada MM, Dugger BN, Flanagan ME, Ghetti B, Grinberg LT, Grossman M, Grothe MJ, Halliday GM, Hasegawa M, Hokkanen SRK, Hunter S, Jellinger K, Kawas CH, Keene CD, Kouri N, Kovacs GG, Leverenz JB, Latimer CS, Mackenzie IR, Mao Q, McAleese KE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Neltner JH, Newell KL, Rissman RA, Saito Y, Sajjadi SA, Schwetye KE, Teich AF, Thal DR, Tom? SO, Troncoso JC, Wang SJ, White CL, Wisniewski T, Yang HS, Schneider JA, Dickson DW, Neumann M. LATE-NC staging in routine neuropathologic diagnosis: an update. Acta Neuropathol. 2023 02; 145(2):159-173. PMID: 36512061.
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    19. Oveisgharan S, Kim N, Agrawal S, Yu L, Leurgans S, Kapasi A, Arfanakis K, Bennett DA, Schneider JA, Buchman AS. Brain and spinal cord arteriolosclerosis and its associations with cerebrovascular disease risk factors in community-dwelling older adults. Acta Neuropathol. 2023 02; 145(2):219-233. PMID: 36469116.
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    20. Oveisgharan S, Dawe RJ, Yu L, Kapasi A, Arfanakis K, Hachinski V, Schneider JA, Bennett DA. Frequency and Underlying Pathology of Pure Vascular Cognitive Impairment. JAMA Neurol. 2022 12 01; 79(12):1277-1286. PMID: 36279115.
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    21. Han SD, Fleischman DA, Yu L, Poole V, Lamar M, Kim N, Leurgans SE, Bennett DA, Arfanakis K, Barnes LL. Cognitive decline and hippocampal functional connectivity within older Black adults. Hum Brain Mapp. 2022 11; 43(16):5044-5052. PMID: 36066181.
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    22. Heywood A, Stocks J, Schneider JA, Arfanakis K, Bennett DA, Beg MF, Wang L. The unique effect of TDP-43 on hippocampal subfield morphometry and cognition. Neuroimage Clin. 2022; 35:103125. PMID: 36002965.
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    23. Abdelhak A, Solomon I, Montes SC, Saias A, Cordano C, Asken B, Fonseca C, Oertel FC, Arfanakis K, Staffaroni AM, Kramer JH, Geschwind M, Miller BL, Elahi FM, Green AJ. Retinal arteriolar parameters as a surrogate marker of intracranial vascular pathology. Alzheimers Dement (Amst). 2022; 14(1):e12338. PMID: 35814617.
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    24. Wu Y, Ridwan AR, Niaz MR, Qi X, Zhang S, Bennett DA, Arfanakis K. Development of high quality T1-weighted and diffusion tensor templates of the older adult brain in a common space. Neuroimage. 2022 10 15; 260:119417. PMID: 35793748.
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    25. Tazwar M, Evia AM, Tamhane AA, Ridwan AR, Leurgans SE, Bennett DA, Schneider JA, Arfanakis K. Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is associated with lower R2 relaxation rate: an ex-vivo MRI and pathology investigation. Neurobiol Aging. 2022 09; 117:128-138. PMID: 35728463.
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    26. Maillard P, Lu H, Arfanakis K, Gold BT, Bauer CE, Zachariou V, Stables L, Wang DJJ, Jann K, Seshadri S, Duering M, Hillmer LJ, Rosenberg GA, Snoussi H, Sepehrband F, Habes M, Singh B, Kramer JH, Corriveau RA, Singh H, Schwab K, Helmer KG, Greenberg SM, Caprihan A, DeCarli C, Satizabal CL. Instrumental validation of free water, peak-width of skeletonized mean diffusivity, and white matter hyperintensities: MarkVCID neuroimaging kits. Alzheimers Dement (Amst). 2022; 14(1):e12261. PMID: 35382232.
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    27. Anad A, Barker MK, Katanga JA, Arfanakis K, Bridges LR, Esiri MM, Isaacs JD, Prpar Mihevc S, Pereira AC, Schneider JA, Hainsworth AH. Vasculocentric Axonal NfH in Small Vessel Disease. J Neuropathol Exp Neurol. 2022 02 24; 81(3):182-192. PMID: 35086142.
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    28. Lamar M, Fleischman DA, Leurgans SE, Aggarwal N, Yu L, Kim N, Poole V, Han SD, Arfanakis K, Barnes LL. Relationship of Blood Pressure and White Matter Hyperintensity Burden With Level of and Change in Cognition in Older Black Adults. Psychosom Med. 2022 05 01; 84(4):437-445. PMID: 35100182.
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    29. Kapasi A, Yu L, Petyuk V, Arfanakis K, Bennett DA, Schneider JA. Association of small vessel disease with tau pathology. Acta Neuropathol. 2022 03; 143(3):349-362. PMID: 35044500.
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    30. van Veluw SJ, Arfanakis K, Schneider JA. Neuropathology of Vascular Brain Health: Insights From Ex Vivo Magnetic Resonance Imaging-Histopathology Studies in Cerebral Small Vessel Disease. Stroke. 2022 02; 53(2):404-415. PMID: 35000425.
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    31. Niaz MR, Ridwan AR, Wu Y, Bennett DA, Arfanakis K. Development and evaluation of a high resolution 0.5mm isotropic T1-weighted template of the older adult brain. Neuroimage. 2022 03; 248:118869. PMID: 34986396.
      Citations:    
    32. Nag S, Chen EY, Johnson R, Tamhane A, Arfanakis K, Schneider JA. Ex vivo MRI facilitates localization of cerebral microbleeds of different ages during neuropathology assessment. Free Neuropathol. 2021 Jan; 2. PMID: 37284642.
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    33. Oveisgharan S, Yu L, Poole VN, Evia AM, Barnes LL, Schneider JA, Arfanakis K, Bennett DA, Buchman AS. Association of White Matter Hyperintensities With Pathology and Progression of Parkinsonism in Aging. JAMA Neurol. 2021 12 01; 78(12):1494-1502. PMID: 34724033.
      Citations:    
    34. Fleischman DA, Arfanakis K, Leurgans SE, Zhang S, Poole VN, Han SD, Yu L, Lamar M, Kim N, Bennett DA, Barnes LL. Associations of deformation-based brain morphometry with cognitive level and decline within older Blacks without dementia. Neurobiol Aging. 2022 03; 111:35-43. PMID: 34963062.
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    35. Krueger KR, Dhana K, Aggarwal NT, Arfanakis K, Carey VJ, Sacks FM, Barnes LL. Properties of the Cognitive Function Battery for the MIND Diet Intervention to Prevent Alzheimer's Disease. J Int Neuropsychol Soc. 2022 09; 28(8):790-797. PMID: 34612190.
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    36. Lamar M, Leurgans S, Kapasi A, Barnes LL, Boyle PA, Bennett DA, Arfanakis K, Schneider JA. Complex Profiles of Cerebrovascular Disease Pathologies in the Aging Brain and Their Relationship With Cognitive Decline. Stroke. 2022 01; 53(1):218-227. PMID: 34601898.
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    37. Agrawal S, Yu L, Nag S, Arfanakis K, Barnes LL, Bennett DA, Schneider JA. The association of Lewy bodies with limbic-predominant age-related TDP-43 encephalopathy neuropathologic changes and their role in cognition and Alzheimer's dementia in older persons. Acta Neuropathol Commun. 2021 09 25; 9(1):156. PMID: 34563269.
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    38. Lef?vre-Arbogast S, Dhana K, Aggarwal NT, Zhang S, Agarwal P, Liu X, Laranjo N, Carey V, Sacks F, Barnes LL, Arfanakis K. Vitamin D Intake and Brain Cortical Thickness in Community-Dwelling Overweight Older Adults: A Cross-Sectional Study. J Nutr. 2021 09 04; 151(9):2760-2767. PMID: 34113981.
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    39. Boyle PA, Wang T, Yu L, Wilson RS, Dawe R, Arfanakis K, Schneider JA, Bennett DA. To what degree is late life cognitive decline driven by age-related neuropathologies? Brain. 2021 08 17; 144(7):2166-2175. PMID: 33742668.
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    40. Han SD, Lamar M, Fleischman D, Kim N, Bennett DA, Lewis TT, Arfanakis K, Barnes LL. Self-reported experiences of discrimination in older black adults are associated with insula functional connectivity. Brain Imaging Behav. 2021 Aug; 15(4):1718-1727. PMID: 32720182.
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    41. Makkinejad N, Evia AM, Tamhane AA, Javierre-Petit C, Leurgans SE, Lamar M, Barnes LL, Bennett DA, Schneider JA, Arfanakis K. ARTS: A novel In-vivo classifier of arteriolosclerosis for the older adult brain. Neuroimage Clin. 2021; 31:102768. PMID: 34330087.
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    42. Dawe RJ, Yu L, Leurgans SE, James BD, Poole VN, Arfanakis K, Schneider JA, Bennett DA, Buchman AS. Physical activity, brain tissue microstructure, and cognition in older adults. PLoS One. 2021; 16(7):e0253484. PMID: 34232955.
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    43. Boyle PA, Wang T, Yu L, Wilson RS, Dawe R, Arfanakis K, Schneider JA, Beck T, Rajan KB, Evans D, Bennett DA. The "cognitive clock": A novel indicator of brain health. Alzheimers Dement. 2021 12; 17(12):1923-1937. PMID: 34060702.
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    44. Kim N, Arfanakis K, Leurgans SE, Yang J, Fleischman DA, Han SD, Aggarwal NT, Lamar M, Yu L, Poole VN, Bennett DA, Barnes LL. Bootstrap approach for meta-synthesis of MRI findings from multiple scanners. J Neurosci Methods. 2021 08 01; 360:109229. PMID: 34052288.
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    45. Agrawal S, Yu L, Kapasi A, James BD, Arfanakis K, Barnes LL, Bennett DA, Nag S, Schneider JA. Limbic-predominant age-related TDP-43 encephalopathy neuropathologic change and microvascular pathologies in community-dwelling older persons. Brain Pathol. 2021 05; 31(3):e12939. PMID: 33624322.
      Citations:    
    46. Lu H, Kashani AH, Arfanakis K, Caprihan A, DeCarli C, Gold BT, Li Y, Maillard P, Satizabal CL, Stables L, Wang DJJ, Corriveau RA, Singh H, Smith EE, Fischl B, van der Kouwe A, Schwab K, Helmer KG, Greenberg SM. MarkVCID cerebral small vessel consortium: II. Neuroimaging protocols. Alzheimers Dement. 2021 04; 17(4):716-725. PMID: 33480157.
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    47. Ridwan AR, Niaz MR, Wu Y, Qi X, Zhang S, Kontzialis M, Javierre-Petit C, Tazwar M, Bennett DA, Yang Y, Arfanakis K. Development and evaluation of a high performance T1-weighted brain template for use in studies on older adults. Hum Brain Mapp. 2021 04 15; 42(6):1758-1776. PMID: 33449398.
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    48. Liu X, Morris MC, Dhana K, Ventrelle J, Johnson K, Bishop L, Hollings CS, Boulin A, Laranjo N, Stubbs BJ, Reilly X, Carey VJ, Wang Y, Furtado JD, Marcovina SM, Tangney C, Aggarwal NT, Arfanakis K, Sacks FM, Barnes LL. Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline. Contemp Clin Trials. 2021 03; 102:106270. PMID: 33434704.
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    49. Yu L, Tasaki S, Schneider JA, Arfanakis K, Duong DM, Wingo AP, Wingo TS, Kearns N, Thatcher GRJ, Seyfried NT, Levey AI, De Jager PL, Bennett DA. Cortical Proteins Associated With Cognitive Resilience in Community-Dwelling Older Persons. JAMA Psychiatry. 2020 11 01; 77(11):1172-1180. PMID: 32609320.
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    50. Qi X, Arfanakis K. Regionconnect: Rapidly extracting standardized brain connectivity information in voxel-wise neuroimaging studies. Neuroimage. 2021 01 15; 225:117462. PMID: 33075560.
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    51. Lamar M, Boots EA, Arfanakis K, Barnes LL, Schneider JA. Common Brain Structural Alterations Associated with Cardiovascular Disease Risk Factors and Alzheimer's Dementia: Future Directions and Implications. Neuropsychol Rev. 2020 12; 30(4):546-557. PMID: 33011894.
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    52. Lamar M, Arfanakis K, Yu L, Zhang S, Han SD, Fleischman DA, Bennett DA, Boyle PA. White matter correlates of scam susceptibility in community-dwelling older adults. Brain Imaging Behav. 2020 Oct; 14(5):1521-1530. PMID: 30895444.
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    53. Javierre-Petit C, Schneider JA, Kapasi A, Makkinejad N, Tamhane AA, Leurgans SE, Mehta RI, Barnes LL, Bennett DA, Arfanakis K. Neuropathologic and Cognitive Correlates of Enlarged Perivascular Spaces in a Community-Based Cohort of Older Adults. Stroke. 2020 09; 51(9):2825-2833. PMID: 32757750.
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    54. Arfanakis K, Evia AM, Leurgans SE, Cardoso LFC, Kulkarni A, Alqam N, Lopes LF, Vieira D, Bennett DA, Schneider JA. Neuropathologic Correlates of White Matter Hyperintensities in a Community-Based Cohort of Older Adults. J Alzheimers Dis. 2020; 73(1):333-345. PMID: 31771057.
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    55. Dawe RJ, Yu L, Arfanakis K, Schneider JA, Bennett DA, Boyle PA. Late-life cognitive decline is associated with hippocampal volume, above and beyond its associations with traditional neuropathologic indices. Alzheimers Dement. 2020 01; 16(1):209-218. PMID: 31914231.
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    56. Yu L, Boyle PA, Dawe RJ, Bennett DA, Arfanakis K, Schneider JA. Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons. Neurology. 2020 01 14; 94(2):e142-e152. PMID: 31757868.
      Citations:    
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    89. Felsky D, De Jager PL, Schneider JA, Arfanakis K, Fleischman DA, Arvanitakis Z, Honer WG, Pouget JG, Mizrahi R, Pollock BG, Kennedy JL, Bennett DA, Voineskos AN. Cerebrovascular and microglial states are not altered by functional neuroinflammatory gene variant. J Cereb Blood Flow Metab. 2016 Apr; 36(4):819-30. PMID: 26762507.
      Citations:    
    90. Lim AS, Fleischman DA, Dawe RJ, Yu L, Arfanakis K, Buchman AS, Bennett DA. Regional Neocortical Gray Matter Structure and Sleep Fragmentation in Older Adults. Sleep. 2016 Jan 01; 39(1):227-35. PMID: 26350471.
      Citations:    
    91. Kotrotsou A, Schneider JA, Bennett DA, Leurgans SE, Dawe RJ, Boyle PA, Golak T, Arfanakis K. Neuropathologic correlates of regional brain volumes in a community cohort of older adults. Neurobiol Aging. 2015 Oct; 36(10):2798-805. PMID: 26195068.
      Citations:    
    92. Arvanitakis Z, Fleischman DA, Arfanakis K, Leurgans SE, Barnes LL, Bennett DA. Association of white matter hyperintensities and gray matter volume with cognition in older individuals without cognitive impairment. Brain Struct Funct. 2016 05; 221(4):2135-46. PMID: 25833685.
      Citations:    
    93. Fleischman DA, Yang J, Arfanakis K, Arvanitakis Z, Leurgans SE, Turner AD, Barnes LL, Bennett DA, Buchman AS. Physical activity, motor function, and white matter hyperintensity burden in healthy older adults. Neurology. 2015 Mar 31; 84(13):1294-300. PMID: 25762710.
      Citations:    
    94. Yokoyama JS, Sturm VE, Bonham LW, Klein E, Arfanakis K, Yu L, Coppola G, Kramer JH, Bennett DA, Miller BL, Dubal DB. Variation in longevity gene KLOTHO is associated with greater cortical volumes. Ann Clin Transl Neurol. 2015 Mar; 2(3):215-30. PMID: 25815349.
      Citations:    
    95. Chauhan G, Adams HHH, Bis JC, Weinstein G, Yu L, T?glhofer AM, Smith AV, van der Lee SJ, Gottesman RF, Thomson R, Wang J, Yang Q, Niessen WJ, Lopez OL, Becker JT, Phan TG, Beare RJ, Arfanakis K, Fleischman D, Vernooij MW, Mazoyer B, Schmidt H, Srikanth V, Knopman DS, Jack CR, Amouyel P, Hofman A, DeCarli C, Tzourio C, van Duijn CM, Bennett DA, Schmidt R, Longstreth WT, Mosley TH, Fornage M, Launer LJ, Seshadri S, Ikram MA, Debette S. Association of Alzheimer's disease GWAS loci with MRI markers of brain aging. Neurobiol Aging. 2015 Apr; 36(4):1765.e7-1765.e16. PMID: 25670335.
      Citations:    
    96. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Leurgans S, Bennett DA. Financial literacy is associated with medial brain region functional connectivity in old age. Arch Gerontol Geriatr. 2014 Sep-Oct; 59(2):429-38. PMID: 24893911.
      Citations:    
    97. Dawe RJ, Bennett DA, Schneider JA, Leurgans SE, Kotrotsou A, Boyle PA, Arfanakis K. Ex vivo T2 relaxation: associations with age-related neuropathology and cognition. Neurobiol Aging. 2014 Jul; 35(7):1549-61. PMID: 24582637.
      Citations:    
    98. Varentsova A, Zhang S, Arfanakis K. Development of a high angular resolution diffusion imaging human brain template. Neuroimage. 2014 May 01; 91:177-86. PMID: 24440528.
      Citations:    
    99. Zhang S, Arfanakis K. White matter segmentation based on a skeletonized atlas: effects on diffusion tensor imaging studies of regions of interest. J Magn Reson Imaging. 2014 Nov; 40(5):1189-98. PMID: 24925050.
      Citations:    
    100. Han SD, Boyle PA, Yu L, Fleischman DA, Arfanakis K, Bennett DA. Ventromedial PFC, parahippocampal, and cerebellar connectivity are associated with temporal discounting in old age. Exp Gerontol. 2013 Dec; 48(12):1489-98. PMID: 24135750.
      Citations:    
    101. Arfanakis K, Fleischman DA, Grisot G, Barth CM, Varentsova A, Morris MC, Barnes LL, Bennett DA. Systemic inflammation in non-demented elderly human subjects: brain microstructure and cognition. PLoS One. 2013; 8(8):e73107. PMID: 23991174.
      Citations:    
    102. Fleischman DA, Leurgans S, Arfanakis K, Arvanitakis Z, Barnes LL, Boyle PA, Han SD, Bennett DA. Gray-matter macrostructure in cognitively healthy older persons: associations with age and cognition. Brain Struct Funct. 2014 Nov; 219(6):2029-49. PMID: 23955313.
      Citations:    
    103. Fleischman DA, Yu L, Arfanakis K, Han SD, Barnes LL, Arvanitakis Z, Boyle PA, Bennett DA. Faster cognitive decline in the years prior to MR imaging is associated with smaller hippocampal volumes in cognitively healthy older persons. Front Aging Neurosci. 2013; 5:21. PMID: 23760360.
      Citations:    
    104. Kotrotsou A, Bennett DA, Schneider JA, Dawe RJ, Golak T, Leurgans SE, Yu L, Arfanakis K. Ex vivo MR volumetry of human brain hemispheres. Magn Reson Med. 2014 Jan; 71(1):364-74. PMID: 23440751.
      Citations:    
    105. . Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization. J Magn Reson Imaging. 2013; 37:372-381.
    106. Duke Han S, Buchman AS, Arfanakis K, Fleischman DA, Bennett DA. Functional connectivity networks associated with chronic musculoskeletal pain in old age. Int J Geriatr Psychiatry. 2013 Aug; 28(8):858-67. PMID: 23124844.
      Citations:    
    107. Arvanitakis Z, Brey RL, Rand JH, Schneider JA, Leurgans SE, Yu L, Buchman AS, Arfanakis K, Fleischman DA, Boyle PA, Bennett DA, Levine SR. Antiphospholipid antibodies, brain infarcts, and cognitive and motor decline in aging (ABICMA): design of a community-based, longitudinal, clinical-pathological study. Neuroepidemiology. 2013; 40(2):73-84. PMID: 23095514.
      Citations:    
    108. Zhang S, Arfanakis K. Role of standardized and study-specific human brain diffusion tensor templates in inter-subject spatial normalization. J Magn Reson Imaging. 2013 Feb; 37(2):372-81. PMID: 23034880.
      Citations:    
    109. Tamhane AA, Arfanakis K, Anastasio M, Guo X, Vannier M, Gao JH. Rapid PROPELLER-MRI: a combination of iterative reconstruction and under-sampling. J Magn Reson Imaging. 2012 Nov; 36(5):1241-7. PMID: 22689510.
      Citations:    
    110. Bis JC, DeCarli C, Smith AV, van der Lijn F, Crivello F, Fornage M, Debette S, Shulman JM, Schmidt H, Srikanth V, Schuur M, Yu L, Choi SH, Sigurdsson S, Verhaaren BF, DeStefano AL, Lambert JC, Jack CR, Struchalin M, Stankovich J, Ibrahim-Verbaas CA, Fleischman D, Zijdenbos A, den Heijer T, Mazoyer B, Coker LH, Enzinger C, Danoy P, Amin N, Arfanakis K, van Buchem MA, de Bruijn RF, Beiser A, Dufouil C, Huang J, Cavalieri M, Thomson R, Niessen WJ, Chibnik LB, Gislason GK, Hofman A, Pikula A, Amouyel P, Freeman KB, Phan TG, Oostra BA, Stein JL, Medland SE, Vasquez AA, Hibar DP, Wright MJ, Franke B, Martin NG, Thompson PM, Nalls MA, Uitterlinden AG, Au R, Elbaz A, Beare RJ, van Swieten JC, Lopez OL, Harris TB, Chouraki V, Breteler MM, De Jager PL, Becker JT, Vernooij MW, Knopman D, Fazekas F, Wolf PA, van der Lugt A, Gudnason V, Longstreth WT, Brown MA, Bennett DA, van Duijn CM, Mosley TH, Schmidt R, Tzourio C, Launer LJ, Ikram MA, Seshadri S. Common variants at 12q14 and 12q24 are associated with hippocampal volume. Nat Genet. 2012 Apr 15; 44(5):545-51. PMID: 22504421.
      Citations:    
    111. Han SD, Boyle PA, Arfanakis K, Fleischman DA, Yu L, Edmonds EC, Bennett DA. Neural intrinsic connectivity networks associated with risk aversion in old age. Behav Brain Res. 2012 Feb 01; 227(1):233-40. PMID: 22044475.
      Citations:    
    112. Han SD, Arfanakis K, Fleischman DA, Leurgans SE, Tuminello ER, Edmonds EC, Bennett DA. Functional connectivity variations in mild cognitive impairment: associations with cognitive function. J Int Neuropsychol Soc. 2012 Jan; 18(1):39-48. PMID: 22005016.
      Citations:    
    113. Dawe RJ, Bennett DA, Schneider JA, Arfanakis K. Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study. PLoS One. 2011; 6(10):e26286. PMID: 22043314.
      Citations:    
    114. Wang Y, West JD, Flashman LA, Wishart HA, Santulli RB, Rabin LA, Pare N, Arfanakis K, Saykin AJ. Selective changes in white matter integrity in MCI and older adults with cognitive complaints. Biochim Biophys Acta. 2012 Mar; 1822(3):423-30. PMID: 21867750.
      Citations:    
    115. Zhang S, Peng H, Dawe RJ, Arfanakis K. Enhanced ICBM diffusion tensor template of the human brain. Neuroimage. 2011 Jan 15; 54(2):974-84. PMID: 20851772.
      Citations:    
    116. Fleischman DA, Arfanakis K, Kelly JF, Rajendran N, Buchman AS, Morris MC, Barnes LL, Bennett DA. Regional brain cortical thinning and systemic inflammation in older persons without dementia. J Am Geriatr Soc. 2010 Sep; 58(9):1823-5. PMID: 20863359.
      Citations:    
    117. Tamhane AA, Anastasio MA, Gui M, Arfanakis K. Iterative image reconstruction for PROPELLER-MRI using the nonuniform fast fourier transform. J Magn Reson Imaging. 2010 Jul; 32(1):211-7. PMID: 20578028.
      Citations:    
    118. . Clinical MR Neuroimaging, 2nd Edition. Diffusion and perfusion MR imaging in seizure disorders. 2010; 546-556.
    119. Tamhane AA, Arfanakis K. Motion correction in periodically-rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) and turboprop MRI. Magn Reson Med. 2009 Jul; 62(1):174-82. PMID: 19365858.
      Citations:    
    120. Phan KL, Orlichenko A, Boyd E, Angstadt M, Coccaro EF, Liberzon I, Arfanakis K. Preliminary evidence of white matter abnormality in the uncinate fasciculus in generalized social anxiety disorder. Biol Psychiatry. 2009 Oct 01; 66(7):691-4. PMID: 19362707.
      Citations:    
    121. Dawe RJ, Bennett DA, Schneider JA, Vasireddi SK, Arfanakis K. Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation. Magn Reson Med. 2009 Apr; 61(4):810-8. PMID: 19189294.
      Citations:    
    122. Peng H, Orlichenko A, Dawe RJ, Agam G, Zhang S, Arfanakis K. Development of a human brain diffusion tensor template. Neuroimage. 2009 Jul 15; 46(4):967-80. PMID: 19341801.
      Citations:    
    123. . Handbook of Research on Afvanced Techniques in Diagnostic Imaging and Biomedical Applications. Optimal diffusion encoding strategies for fiber mapping n diffusion MRI. 2009; 90-107.
    124. Gui M, Peng H, Carew JD, Lesniak MS, Arfanakis K. A tractography comparison between turboprop and spin-echo echo-planar diffusion tensor imaging. Neuroimage. 2008 Oct 01; 42(4):1451-62. PMID: 18621131.
      Citations:    
    125. Gui M, Tamhane AA, Arfanakis K. Contribution of cardiac-induced brain pulsation to the noise of the diffusion tensor in Turboprop diffusion tensor imaging (DTI). J Magn Reson Imaging. 2008 May; 27(5):1164-8. PMID: 18425837.
      Citations:    
    126. Lukic AS, Wernick MN, Yang Y, Hansen LK, Arfanakis K, Strother SC. Effect of spatial alignment transformations in PCA and ICA of functional neuroimages. IEEE Trans Med Imaging. 2007 Aug; 26(8):1058-68. PMID: 17695126.
      Citations:    
    127. . Investigating the Medial Temporal Lobe in Alzheimer's Disease and Mild Cognitive Impairment, with Turboprop Diffusion Tensor Imaging, MRI-Volumetry and T2-relaxometry. Brain Imaging and Behav. 2007; 1:11-21.
    128. Peng H, Arfanakis K. Diffusion tensor encoding schemes optimized for white matter fibers with selected orientations. Magn Reson Imaging. 2007 Feb; 25(2):147-53. PMID: 17275608.
      Citations:    
    129. Arfanakis K, Gui M, Lazar M. Optimization of white matter tractography for pre-surgical planning and image-guided surgery. Oncol Rep. 2006; 15(4):1061-1064. PMID: 16525701.
      Citations:    
    130. Arfanakis K, Gui M, Lazar M. White matter tractography by means of Turboprop diffusion tensor imaging. Ann N Y Acad Sci. 2005 Dec; 1064:78-87. PMID: 16394149.
      Citations:    
    131. Arfanakis K, Tamhane AA, Pipe JG, Anastasio MA. k-space undersampling in PROPELLER imaging. Magn Reson Med. 2005 Mar; 53(3):675-83. PMID: 15723398.
      Citations:    
    132. . Imaging of the Nervous System: Diagnostic and Therapeutic Applications, Philadelphia, PA. Mapping brain function with functional magnetic resonance imaging. 2005; 89-100.
    133. . Clinical MR Neuroimaging: Diffusion, Perfusion and Spectroscopy. Diffusion and perfusion MR imaging in seizure disorders. 2005; 509-520.
    134. Hurley RA, McGowan JC, Arfanakis K, Taber KH. Traumatic axonal injury: novel insights into evolution and identification. J Neuropsychiatry Clin Neurosci. 2004; 16(1):1-7. PMID: 14990753.
      Citations:    
    135. Field AS, Hasan K, Jellison BJ, Arfanakis K, Alexander AL. Diffusion tensor imaging in an infant with traumatic brain swelling. AJNR Am J Neuroradiol. 2003 Aug; 24(7):1461-4. PMID: 12917147.
      Citations:    
    136. Lazar M, Weinstein DM, Tsuruda JS, Hasan KM, Arfanakis K, Meyerand ME, Badie B, Rowley HA, Haughton V, Field A, Alexander AL. White matter tractography using diffusion tensor deflection. Hum Brain Mapp. 2003 Apr; 18(4):306-21. PMID: 12632468.
      Citations:    
    137. Rogers BP, Haughton VM, Arfanakis K, Meyerand ME. Application of image registration to measurement of intervertebral rotation in the lumbar spine. Magn Reson Med. 2002 Dec; 48(6):1072-5. PMID: 12465120.
      Citations:    
    138. Witwer BP, Moftakhar R, Hasan KM, Deshmukh P, Haughton V, Field A, Arfanakis K, Noyes J, Moritz CH, Meyerand ME, Rowley HA, Alexander AL, Badie B. Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm. J Neurosurg. 2002 Sep; 97(3):568-75. PMID: 12296640.
      Citations:    
    139. Arfanakis K, Hermann BP, Rogers BP, Carew JD, Seidenberg M, Meyerand ME. Diffusion tensor MRI in temporal lobe epilepsy. Magn Reson Imaging. 2002 Sep; 20(7):511-9. PMID: 12413596.
      Citations:    
    140. Laird AR, Rogers BP, Carew JD, Arfanakis K, Moritz CH, Meyerand ME. Characterizing instantaneous phase relationships in whole-brain fMRI activation data. Hum Brain Mapp. 2002 Jun; 16(2):71-80. PMID: 11954057.
      Citations:    
    141. Cordes D, Haughton V, Carew JD, Arfanakis K, Maravilla K. Hierarchical clustering to measure connectivity in fMRI resting-state data. Magn Reson Imaging. 2002 May; 20(4):305-17. PMID: 12165349.
      Citations:    
    142. Arfanakis K, Haughton VM, Carew JD, Rogers BP, Dempsey RJ, Meyerand ME. Diffusion tensor MR imaging in diffuse axonal injury. AJNR Am J Neuroradiol. 2002 May; 23(5):794-802. PMID: 12006280.
      Citations:    
    143. Arfanakis K, Cordes D, Haughton VM, Carew JD, Meyerand ME. Independent component analysis applied to diffusion tensor MRI. Magn Reson Med. 2002 Feb; 47(2):354-63. PMID: 11810680.
      Citations:    
    144. . Application of image registration to measurement of intervertebral rotation in the lumbar spine. Magn Reson Med. 2002; 48:1072-1075.
    145. Cordes D, Haughton VM, Arfanakis K, Carew JD, Turski PA, Moritz CH, Quigley MA, Meyerand ME. Frequencies contributing to functional connectivity in the cerebral cortex in "resting-state" data. AJNR Am J Neuroradiol. 2001 Aug; 22(7):1326-33. PMID: 11498421.
      Citations:    
    146. Arfanakis K, Cordes D, Haughton VM, Moritz CH, Quigley MA, Meyerand ME. Combining independent component analysis and correlation analysis to probe interregional connectivity in fMRI task activation datasets. Magn Reson Imaging. 2000 Oct; 18(8):921-30. PMID: 11121694.
      Citations:    
    147. Cordes D, Haughton VM, Arfanakis K, Wendt GJ, Turski PA, Moritz CH, Quigley MA, Meyerand ME. Mapping functionally related regions of brain with functional connectivity MR imaging. AJNR Am J Neuroradiol. 2000 Oct; 21(9):1636-44. PMID: 11039342.
      Citations:    
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