"Isoproterenol" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Isopropyl analog of EPINEPHRINE; beta-sympathomimetic that acts on the heart, bronchi, skeletal muscle, alimentary tract, etc. It is used mainly as bronchodilator and heart stimulant.
| Descriptor ID |
D007545
|
| MeSH Number(s) |
D02.033.100.291.439 D02.092.063.291.439 D02.092.311.649
|
| Concept/Terms |
Isoproterenol- Isoproterenol
- Isoprenaline
- Isopropylnorepinephrine
- Isopropylarterenol
- Isopropylnoradrenaline
- 4-(1-Hydroxy-2-((1-methylethyl)amino)ethyl)-1,2-benzenediol
- Isopropyl Noradrenaline
- Noradrenaline, Isopropyl
|
Below are MeSH descriptors whose meaning is more general than "Isoproterenol".
Below are MeSH descriptors whose meaning is more specific than "Isoproterenol".
This graph shows the total number of publications written about "Isoproterenol" by people in this website by year, and whether "Isoproterenol" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 1 | 2 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 2 | 2 |
| 2017 | 0 | 2 | 2 |
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Below are the most recent publications written about "Isoproterenol" by people in Profiles.
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Ero1a-Dependent ERp44 Dissociation From RyR2 Contributes to Cardiac Arrhythmia. Circ Res. 2022 03 04; 130(5):711-724.
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Proinflammatory Cytokines Are Soluble Mediators Linked with Ventricular Arrhythmias and Contractile Dysfunction in a Rat Model of Metabolic Syndrome. Oxid Med Cell Longev. 2017; 2017:7682569.
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Metabolic inhibition reduces cardiac L-type Ca2+ channel current due to acidification caused by ATP hydrolysis. PLoS One. 2017; 12(8):e0184246.
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Inositol 1,4,5-trisphosphate-mediated sarcoplasmic reticulum-mitochondrial crosstalk influences adenosine triphosphate production via mitochondrial Ca2+ uptake through the mitochondrial ryanodine receptor in cardiac myocytes. Cardiovasc Res. 2016 10; 112(1):491-501.
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Cardiac responses to ß-adrenoceptor stimulation is partly dependent on mitochondrial calcium uniporter activity. Br J Pharmacol. 2014 Sep; 171(18):4207-21.
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Nitric oxide-dependent activation of CaMKII increases diastolic sarcoplasmic reticulum calcium release in cardiac myocytes in response to adrenergic stimulation. PLoS One. 2014; 9(2):e87495.
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Isoproterenol increases the fraction of spark-dependent RyR-mediated leak in ventricular myocytes. Biophys J. 2013 Mar 05; 104(5):976-85.
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?-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca2+ threshold for Ca2+ wave generation. J Physiol. 2012 Dec 01; 590(23):6093-108.
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Absence of myocardial thyroid hormone inactivating deiodinase results in restrictive cardiomyopathy in mice. Mol Endocrinol. 2012 May; 26(5):809-18.
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Effects of increased systolic Ca?? and phospholamban phosphorylation during ?-adrenergic stimulation on Ca?? transient kinetics in cardiac myocytes. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1570-8.